Modulation of Protein-protein Interactions by Small-molecule Inducers of Proteasomal Protein Degradation PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Modulation of Protein-protein Interactions by Small-molecule Inducers of Proteasomal Protein Degradation PDF full book. Access full book title Modulation of Protein-protein Interactions by Small-molecule Inducers of Proteasomal Protein Degradation by Florian Nietzold. Download full books in PDF and EPUB format.
Author: Florian Nietzold
Publisher:
ISBN:
Category :
Languages : de
Pages :
Get Book Here
Book Description
Author: Florian Nietzold
Publisher:
ISBN:
Category :
Languages : de
Pages :
Get Book Here
Book Description
Author: Joseph William Barco
Publisher:
ISBN:
Category :
Languages : en
Pages : 376
Get Book Here
Book Description
Author: Sumit Mittal
Publisher:
ISBN:
Category :
Languages : en
Pages :
Get Book Here
Book Description
Author: Stefano Mangani
Publisher: Springer Science & Business Media
ISBN: 3642379990
Category : Science
Languages : en
Pages : 167
Get Book Here
Book Description
"Disruption of Protein-Protein Interfaces" reviews the latest developments and future perspectives in drug discovery at protein-protein interfaces. The authors detail experimental and computational tools to tackle the subject and highlight the contribution of the Italian research community to the field. Evidence shows that blocking or modulating protein-protein interactions might lead to the development of useful new drugs. Consequently, in recent years great effort has been dedicated to unveiling the molecular details of protein-protein interfaces by structural techniques e.g. X-ray diffraction, NMR spectroscopy. This book, written and edited by leaders in the field, provides examples from the literature of successes and failures to develop drug-like molecules effective in interacting at protein-protein interfaces.
Author: Pascal Markus Engelhardt
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Get Book Here
Book Description
Author: Craig Crews
Publisher: Royal Society of Chemistry
ISBN: 1788016866
Category : Medical
Languages : en
Pages : 382
Get Book Here
Book Description
Targeting protein degradation using small molecules is one of the most exciting small-molecule therapeutic strategies in decades and a rapidly growing area of research. In particular, the development of proteolysis targeting chimera (PROTACs) as potential drugs capable of recruiting target proteins to the cellular quality control machinery for elimination has opened new avenues to address traditionally 'difficult to target' proteins. This book provides a comprehensive overview from the leading academic and industrial experts on recent developments, scope and limitations in this dynamically growing research area; an ideal reference work for researchers in drug discovery and chemical biology as well as advanced students.
Author: Christian Lis
Publisher:
ISBN:
Category :
Languages : en
Pages :
Get Book Here
Book Description
Author: Siddhartha Roy
Publisher: Royal Society of Chemistry
ISBN: 1839160500
Category : Science
Languages : en
Pages : 399
Get Book Here
Book Description
New genomic information has revealed the crucial role that protein–protein interactions (PPIs) play in regulating numerous cellular functions. Aberrant forms of these interactions are common in numerous diseases and thus PPIs have emerged as a vast class of critical drug targets. Despite the importance of PPIs in biology, it has been extremely challenging to convert targets into therapeutics and targeting PPIs had long been considered a very difficult task. However, over the past decade the field has advanced with increasing growth in the number of successful PPI regulators. Protein–Protein Interaction Regulators surveys the latest advances in the structural understanding of PPIs as well as recent developments in modulator discovery.
Author:
Publisher: Elsevier
ISBN: 0323992013
Category : Science
Languages : en
Pages : 342
Get Book Here
Book Description
Targeted Protein Degradation, Volume 680 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of timely topics, with each. Each written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Methods in Enzymology serials Updated release includes the latest information on Targeted Protein Degradation
Author: Lyubomir Vassilev
Publisher: Springer Science & Business Media
ISBN: 3642170838
Category : Medical
Languages : en
Pages : 180
Get Book Here
Book Description
In this volume, the editors have collected the knowledgeable insights of a number of leaders in this field - researchers who have achieved success in addressing the difficult problem of inhibiting protein-protein interactions. These researchers describe their unique approaches, and share experiences, results, thoughts, and opinions. The content of the articles is rich, and in terms of scope ranges from generalized approaches to specific case studies. There are various focal points, including methodologies and the molecules themselves. Ultimately, there are numerous lessons to be taken away from this collection, and the editors hope that this snapshot of the current state of the art in developing protein-protein inhibitors not only pays tribute to the past successes, but also generates excitement about the future potential of this field
