Modified Nucleosides in Cancer and Normal Metabolism - Methods and Applications

Modified Nucleosides in Cancer and Normal Metabolism - Methods and Applications PDF Author:
Publisher: Elsevier
ISBN: 9780080858524
Category : Science
Languages : en
Pages : 447

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Book Description
Modified Nucleosides in Cancer and Normal Metabolism - Methods and Applications

Modified Nucleosides and Cancer

Modified Nucleosides and Cancer PDF Author: G. Nass
Publisher: Springer Science & Business Media
ISBN: 3642819478
Category : Medical
Languages : en
Pages : 441

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Book Description
This book comprises the lectures presented at the workshop Modified Nuc1eosides and Cancer held from 28 September to 2 October, 1981 in Freiburg, West Germany. The workshop was organized by Gisela Nass and sponsored by the Deutsche Forschungsgemeinschaft. The purpose of the workshop was to cover the varied analytical methods for quantitative and qualitative determination of modified nucleosides and their metabolism including bio synthesis, all in relation to the function of these compounds in the origin and growth of cancer cells. The potential signi ficance of measuring modified nucleosides in body fluids for tumor diagnosis in humans received particular attention. Various fields of research which have previously been segregat ed are thus unified in this volume. Emphasis was also placed on the fact that modified nucleosides are constituents of the genetic material, the desoxyribonucleic> acid, on the one hand, and of the transfer ribonucleic acids on the other hand, with the latter macromolecules participating not only in the translation of genetic information into protein, but also in many regulatory processes in all single- and multi-, cellular organisms including man.

Analytical Methods for Major and Modified Nucleosides - HPLC, GC, MS, NMR, UV and FT-IR

Analytical Methods for Major and Modified Nucleosides - HPLC, GC, MS, NMR, UV and FT-IR PDF Author:
Publisher: Elsevier
ISBN: 9780080858500
Category : Science
Languages : en
Pages : 395

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Book Description
Analytical Methods for Major and Modified Nucleosides - HPLC, GC, MS, NMR, UV and FT-IR

Biological Roles and Function of Modification

Biological Roles and Function of Modification PDF Author:
Publisher: Elsevier
ISBN: 9780080858517
Category : Science
Languages : en
Pages : 364

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Book Description
Biological Roles and Function of Modification

Applications

Applications PDF Author:
Publisher: Elsevier
ISBN: 9780080858593
Category : Science
Languages : en
Pages : 624

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Book Description
Applications

Applications of LC-MS in Environmental Chemistry

Applications of LC-MS in Environmental Chemistry PDF Author: Damia Barcelo
Publisher: Elsevier
ISBN: 9780080858678
Category : Science
Languages : en
Pages : 540

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Book Description
Looking at the literature available, it is clear that there is a need for a book on LC-MS applications in environmental analysis. This book endeavours to answer the following questions: What interface to use to solve "my detection problem"? Can I obtain enough sensitivity for the confirmation of my compound in real-world environmental samples? Is there enough structural information? The present book aims to provide a critical evaluation of LC-MS in environmental chemistry and it is structured in different areas. Apart from an introductory section with fundamental aspects, application areas using the most relevant interfacing systems (PB, TSP, ES) for the characterization of environmental compounds are included. In this sense, applications are discussed on the characterization of the most relevant compounds of environmental interest such as pesticides, detergents, dyes, polar metabolites, waste streams, organotin compounds and marine toxins with comparison between different interfacing systems. Finally, new methods and strategies in LC-MS, e.g. the use of capillary electrophoresis, MS together with on-line post-column systems in LC-MS are also shown. By the nature of its content and written as it is by experienced practitioners, the book is intended to serve as a practical reference for analytical chemists who need to use LC-MS in environmental studies. Each chapter includes sufficient references to the literature to serve as a valuable starting point and also contains detailed investigations. The broad spectrum of the book and its application to environmental priority compounds makes it unique in many ways.

Advanced Chromatographic and Electromigration Methods in BioSciences

Advanced Chromatographic and Electromigration Methods in BioSciences PDF Author: I. Mikšík
Publisher: Elsevier
ISBN: 0080858686
Category : Science
Languages : en
Pages : 1149

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Book Description
This book deals with chromatographic and electrophoretic methods applied for the separation (quantitation and identification) of biologically relevant compounds. It is assumed that the potential reader is familiar with the basics of chromatographic and electromigration methods. Individual separation modes are dealt with to an extent which follows their applicability for biomedical purposes: liquid chromatography and electromigration methods are therefore highlighted. Each chapter is completed with a list of recent literature covering the 1987-1997 period, which can be used for further guidance of the reader in his/her own field. The chapters have been written by specialists in a particular area and with an emphasis on applications to the biomedical field. This implies that theoretical and instrumental aspects are kept to a minimum which allows the reader to understand the text. Considerable attention is paid to method selection, detection and derivatization procedures and troubleshooting. The majority of examples given represent the analyses of typical naturally-occurring mixtures. Adequate attention is paid to the role of the biological matrix and sample pretreatment, and special attention is given to forensic, toxicological and clinical applications. The book is completed with an extensive Index of Compounds Separated.

A Century of Separation Science

A Century of Separation Science PDF Author: Haleem J. Issaq
Publisher: CRC Press
ISBN: 1482270927
Category : Science
Languages : en
Pages : 776

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Book Description
A Century of Separation Science presents an extensive overview of the critical developments in separation science since 1900, covering recent advances in chromatography, electrophoresis, field-flow fractionation, countercurrent chromatography, and supercritical fluid chromatography for high-speed and high-throughput analysis.

Fundamentals and Techniques

Fundamentals and Techniques PDF Author:
Publisher: Elsevier
ISBN: 9780080858586
Category : Science
Languages : en
Pages : 588

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Book Description
Fundamentals and Techniques

Chromatography of Mycotoxins

Chromatography of Mycotoxins PDF Author: V. Betina
Publisher: Elsevier
ISBN: 9780080858623
Category : Science
Languages : en
Pages : 433

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Book Description
This work comprises two parts, Part A: Techniques and Part B: Applications. In Part A the most important principles of sample preparation, extraction, clean-up, and of established and prospective chromatographic techniques are discussed in relation to mycotoxins. In Part B the most important data, scattered in the literature, on thin-layer, liquid, and gas chromatography of mycotoxins have been compiled. Mycotoxins are mostly arranged according to families, such as aflatoxins, trichothecenes, lactones etc. Chromatography of individual important mycotoxins and multi-mycotoxin chromatographic analyses are also included. Applications are presented in three chapters devoted to thin-layer, liquid, and gas chromatography of mycotoxins.