Modification of Vestibular Sensitivity in the Rat PDF Download
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Author: David C. Riccio
Publisher:
ISBN:
Category : Vestibular apparatus
Languages : en
Pages : 28
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Book Description
A study was made to determine the effects of vestibular damage or previous vestibular stimulation on the spontaneous activity of the rat during rotation. Unilateral destruction of the labyrinth through intratympanic injections of streptomycin sulfate decreased the sensitivity of unrestrained rats to rotation, as measured by the maintenance of high levels of spontaneous locomotor activity during rotation. Repeated exposure to rotation produced a similar threshold shift in undamaged rats. Normal control animals showed a marked decrement in activity while rotated. Rats were extremely resistant to streptomycin sulfate injected systemically; neither morphological damage to hair cells nor changes in the response to vestibular stimulation was found following a total dosage of 10,000 mg of the drug. The findings demonstrated that the spontaneous activity levels provide a sensitive behavioral measure of the effects of vestibular stimulation on the rat. (Author).
Author: David C. Riccio
Publisher:
ISBN:
Category : Vestibular apparatus
Languages : en
Pages : 28
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Book Description
A study was made to determine the effects of vestibular damage or previous vestibular stimulation on the spontaneous activity of the rat during rotation. Unilateral destruction of the labyrinth through intratympanic injections of streptomycin sulfate decreased the sensitivity of unrestrained rats to rotation, as measured by the maintenance of high levels of spontaneous locomotor activity during rotation. Repeated exposure to rotation produced a similar threshold shift in undamaged rats. Normal control animals showed a marked decrement in activity while rotated. Rats were extremely resistant to streptomycin sulfate injected systemically; neither morphological damage to hair cells nor changes in the response to vestibular stimulation was found following a total dosage of 10,000 mg of the drug. The findings demonstrated that the spontaneous activity levels provide a sensitive behavioral measure of the effects of vestibular stimulation on the rat. (Author).
Author: David C. Riccio
Publisher:
ISBN:
Category :
Languages : en
Pages : 18
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Book Description
A study was made to determine the effects of vestibular damage or previous vestibular stimulation on the spontaneous activity of the rat during rotation. Unilateral destruction of the labyrinth through intratympanic injections of streptomycin sulfate decreased the sensitivity of unrestrained rats to rotation, as measured by the maintenance of high levels of spontaneous locomotor activity during rotation. Repeated exposure to rotation produced a similar threshold shift in undamaged rats. Normal control animals showed a marked decrement in activity while rotated. Rats were extremely resistant to streptomycin sulfate injected systemically; neither morphological damage to hair cells nor changes in the response to vestibular stimulation was found following a total dosage of 10,000 mg of the drug. The findings demonstrated that the spontaneous activity levels provide a sensitive behavioral measure of the effects of vestibular stimulation on the rat. (Author).
Author: Michel Lacour
Publisher:
ISBN:
Category : Nervous system
Languages : en
Pages : 324
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Author: United States. National Aeronautics and Space Administration Scientific and Technical Information Division
Publisher:
ISBN:
Category : Aeronautics
Languages : en
Pages : 2300
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Author:
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 776
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Author:
Publisher:
ISBN:
Category : Aeronautics
Languages : en
Pages : 1108
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Author:
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 328
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Author: Naval School of Aviation Medicine (U.S.)
Publisher:
ISBN:
Category :
Languages : en
Pages : 304
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Author: Jordi Llorens
Publisher: Springer Nature
ISBN: 1071616374
Category : Medical
Languages : en
Pages : 488
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Book Description
This volume explores the latest methods that seek to address the vital questions being asked in neurotoxicology research. The chapters in this book cover a variety of available methods from the molecular level to the organism level, and both in vitro and in vivo approaches, including alternative model organisms. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and authoritative, Experimental Neurotoxicology Methods is a valuable resource for both young and experienced researchers who are looking for guidance to implement these methods in their laboratories or for understanding the data generated through these techniques.
Author: United States. National Aeronautics and Space Administration. Scientific and Technical Information Division
Publisher:
ISBN:
Category : Aeronautics
Languages : en
Pages : 2088
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Book Description
