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Author: Mikhail Pletnikov
Publisher: Academic Press
ISBN: 012801184X
Category : Psychology
Languages : en
Pages : 550
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Book Description
Modeling the Psychopathological Dimensions of Schizophrenia: From Molecules to Behavior is the first book to offer a comprehensive review of the new theoretical, clinical, and basic research framework that considers psychotic illness as a group of dimensional representations of psychopathology rather than as traditional distinct categorical diagnoses. Psychotic illness, typified by schizophrenia, is a devastating condition increasingly recognized as a disorder of abnormal brain development and dysconnectivity. Its complex etiology involves both genetic and environmental factors, as well as the interplay among them. This book describes the current understanding of the clinical and pathological features of schizophrenia, with a particular focus on the evolving conceptualization of schizophrenia and related diagnostic categories of psychotic illness as combinations of dimensional abnormalities. It provides an overview of modern strategies for generating cellular and whole animal models of schizophrenia as well as detailed reviews of the specific experimental preparations and paradigms aimed at molecular, developmental, and brain-network mechanisms that are the underlying aspects of abnormal behavior and various aspects of schizophrenia. This groundbreaking book is an authoritative overview of the translational impact of emerging clinical insights on basic research approaches in schizophrenia that will advance the reader's understanding of the five major dimensions of psychopathology in schizophrenia and related psychoses and resolve the genetic and neurobiological underpinnings of these dimensions. - Includes reviews of animal models that capture the most recent insights into the etiology and pathogenetic mechanisms of schizophrenia, with an emphasis on the translational potential of these models - Contains a series of reviews of recently available cellular models for analysis of signaling pathways and gene expression, which complement behavioral neuroscience research in schizophrenia - Edited and authored by leading researchers in the field of schizophrenia and related psychoses
Author: Mikhail Pletnikov
Publisher: Academic Press
ISBN: 012801184X
Category : Psychology
Languages : en
Pages : 550
Get Book Here
Book Description
Modeling the Psychopathological Dimensions of Schizophrenia: From Molecules to Behavior is the first book to offer a comprehensive review of the new theoretical, clinical, and basic research framework that considers psychotic illness as a group of dimensional representations of psychopathology rather than as traditional distinct categorical diagnoses. Psychotic illness, typified by schizophrenia, is a devastating condition increasingly recognized as a disorder of abnormal brain development and dysconnectivity. Its complex etiology involves both genetic and environmental factors, as well as the interplay among them. This book describes the current understanding of the clinical and pathological features of schizophrenia, with a particular focus on the evolving conceptualization of schizophrenia and related diagnostic categories of psychotic illness as combinations of dimensional abnormalities. It provides an overview of modern strategies for generating cellular and whole animal models of schizophrenia as well as detailed reviews of the specific experimental preparations and paradigms aimed at molecular, developmental, and brain-network mechanisms that are the underlying aspects of abnormal behavior and various aspects of schizophrenia. This groundbreaking book is an authoritative overview of the translational impact of emerging clinical insights on basic research approaches in schizophrenia that will advance the reader's understanding of the five major dimensions of psychopathology in schizophrenia and related psychoses and resolve the genetic and neurobiological underpinnings of these dimensions. - Includes reviews of animal models that capture the most recent insights into the etiology and pathogenetic mechanisms of schizophrenia, with an emphasis on the translational potential of these models - Contains a series of reviews of recently available cellular models for analysis of signaling pathways and gene expression, which complement behavioral neuroscience research in schizophrenia - Edited and authored by leading researchers in the field of schizophrenia and related psychoses
Author: Philip D. Harvey
Publisher: Cambridge University Press
ISBN: 1107013208
Category : Medical
Languages : en
Pages : 341
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Book Description
Provides state-of-the-art information about cognition in schizophrenia with a wide ranging focus on measuring and treating cognitive deficits.
Author: Massimo Biondi
Publisher: Springer
ISBN: 3319782029
Category : Medical
Languages : en
Pages : 307
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Book Description
This book presents an innovative approach to clinical assessment in psychiatry based on a number of psychopathological dimensions with a presumed underlying pathophysiology, that are related to fundamental phenomenological aspects and lie on a continuum from normality to pathology. It is described how the evaluation of these dimensions with a specific, validated rapid assessment instrument could easily integrate and enrich the classical diagnostic DSM-5 or ICD-10 assessment. The supplemental use of this dimensional approach can better capture the complexity underlying current categories of mental illness. The findings from a large patient sample suggest how this assessment could give a first glance at how variable and multifaceted the psychopathological components within a single diagnostic category can be, and thereby optimise diagnosis and treatment choices. Being short and easy to complete, this dimensional assessment can be done in a busy clinical setting, during an ordinary psychiatric visit, and in an acute clinical context, with limited effort by a minimally trained clinician. Therefore, it provides interesting and useful information without additional costs, and allows research work to be performed even in difficult settings.
Author: Carol A. Tamminga MD
Publisher: Oxford University Press
ISBN: 0190653299
Category : Medical
Languages : en
Pages : 709
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Book Description
Psychotic Disorders: Comprehensive Conceptualization and Treatments emphasizes a dimensional approach to psychosis--one of the most fascinating manifestations of altered brain behavior--that cuts across a broad array of psychiatric diagnoses from schizophrenia to affective psychosis and organic disorders like epilepsy and dementias. Written by an international roster of over seventy leading experts in the field, this volume comprehensively reviews, critiques, and integrates available knowledge on the etiology, mechanisms, and treatments of psychotic disorders, and outlines ways forward in both research and clinical practice towards more objective, mechanistically-based definitions of psychotic disorders. Chapters address topics such as psychosis phenomenology, biomarkers and treatments, the overlaps and interfaces between psychiatric disorders within the psychosis dimension, and novel disease definitions. Furthermore, the volume incorporates findings on potential mechanisms, bridges between various system levels (i.e., genetic, epigenetic, molecular and cellular, brain circuit and function, psychological, social, environmental and cultural) and their interactions, as well as the potential role in causation and/or mediation in psychotic disorders. Finally, the volume outlines a broad array of treatment approaches, from the readily available (e.g., psychopharmacology, various modalities of psychotherapy) to the experimental (e.g., cognitive interventions, neuromodulation). With a concluding section of forward perspectives conjecturing future directions and related challenges, this book aspires to stimulate new knowledge, generate novel frameworks, and carry new directions forward on psychotic disorders.
Author: Robin M. Murray
Publisher: Cambridge University Press
ISBN: 9780521121026
Category : Medical
Languages : en
Pages : 0
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Book Description
An international team of leading researchers and clinicians provides the first comprehensive, epidemiological overview of this multi-faceted and still-perplexing disorder. Controversial issues such as the validity of discrete or dimensional classifications of schizophrenia and the continuum between psychosis and 'normality' are explored in depth. Separate chapters are devoted to topics of particular relevance to schizophrenia such as suicide, violence and substance abuse. Finally, new prospects for treatment and prevention are considered.
Author: Giovanni Stanghellini
Publisher:
ISBN: 019960925X
Category : Medical
Languages : en
Pages : 345
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Book Description
2013 sees the centenary of Jaspers' foundation of psychopathology as a science with the publication of his magnum opus the Allgemeine Psychopathologie (General Psychopathology), Many of the issues concerning methodology and diagnosis are today the subject of much discussion and debate. This volume brings together leading psychiatrists and philosophers to discuss the impact of this volume, its relevance today, and the legacy it left.
Author: EUGENE. MINKOWSKI
Publisher:
ISBN: 9780810140608
Category :
Languages : en
Pages : 344
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Book Description
Eugène Minkowski's Lived Time articulates a phenomenology of time that is as inspired by the philosophical writings of Henri Bergson and Edmund Husserl as it is by the psychiatric descriptions of Eugen Bleuler. After providing a phenomenological description of the experience of time in normal life, Minkowski considers a number of mental illnesses, including schizophrenia, manic depression, and dementia, and he attempts to show that these pathological cases can be characterized in terms of a distortion of lived time and space. First published in French in 1933 as Le temps vécu, this edition of this classic work of phenomenological psychiatry and psychopathology includes a new foreword by Dan Zahavi that presents some of Minkowski's main ideas and discusses his contemporary relevance.
Author: Richard P Bentall
Publisher: Penguin UK
ISBN: 0141909323
Category : Psychology
Languages : en
Pages : 557
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Book Description
A revised edition of Madness Explained, Richard Bentall's groundbreaking classic on mental illness In Madness Explained, leading clinical psychologist Richard Bentall shatters the modern myths that surround psychosis. Is madness purely a medical condition that can be treated with drugs? Is there a clear dividing line between who is sane and who is insane? For this revised edition, he adds new material drawing on the recent advances in molecular genetics, new studies of the role of environment in psychosis, and important discoveries on early symptoms preceding illness, among other important developments in our understanding. 'Madness Explained is a substantial, yet highly accessible work. Full of insight and humanity, it deserves a wide readership.' Sunday Times 'Will give readers a glimpse both of answers to their own problems, and to questions about how the mind works' Independent Magazine Richard P. Bentall holds a Chair in Experimental Clinical Psychology at the University of Manchester. In 1989 he received the British Psychological Society's May Davidson Award for his contribution to the field of Clinical Psychology.
Author: Michael Poyurovsky
Publisher: Cambridge University Press
ISBN: 1107000122
Category : Medical
Languages : en
Pages : 249
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Book Description
This is the first book to address the clinical and neurobiological interface between schizophrenia and obsessive-compulsive disorder (OCD). There is growing evidence that obsessive-compulsive symptoms in schizophrenia are prevalent, persistent and characterized by a distinct pattern of familial inheritance, neurocognitive deficits and brain activation. This text provides guidelines for differential diagnosis of schizophrenic patients with obsessive-compulsive symptoms, and patients with primary OCD alongside poor insight, psychotic features or schizotypal personality. Written by a leading expert in the coexistence of obsessive-compulsive and schizophrenic phenomena, Schizo-Obsessive Disorder uses numerous case studies to present diagnostic guidelines and to describe a recommended treatment algorithm, demystifying this complex disorder and aiding its effective management. The book is essential reading for psychiatrists, neurologists and the wider range of multidisciplinary mental health practitioners.
Author: Matcheri Keshavan
Publisher: Cambridge University Press
ISBN: 1107194784
Category : Medical
Languages : en
Pages : 199
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Book Description
A practical guide on how to assess and treat schizophrenia and related disorders using cognitive rehabilitation.
