Mitochondria and Bacterial Pathogens - Part A PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Mitochondria and Bacterial Pathogens - Part A PDF full book. Access full book title Mitochondria and Bacterial Pathogens - Part A by . Download full books in PDF and EPUB format.
Author:
Publisher: Elsevier
ISBN: 0323994113
Category : Science
Languages : en
Pages : 210
Get Book Here
Book Description
Mitochondria and Bacterial Pathogens, Volume 374, Part A. Mitochondria control various processes that are integral to cellular and organismal homeostasis, including Ca2+ fluxes, bioenergetic metabolism, and cell death. Perhaps not surprisingly, multiple pathogenic bacteria have evolved strategies to subvert mitochondrial functions in support of their survival and dissemination. In the IRCMB volume 375, the authors discus different pathogenic mechanisms that converge on the ability of bacteria to control the mitochondrial compartment of host cells. - Collection of articles reporting the role of mitochondria during bacterial infection - Mitochondria, the evolutionary successors of an ancient endosymbiotic prokaryote, occupy a central position in the biology of modern eukaryotic cells - Numerous pathogenic bacteria have evolved strategies to subvert the mitochondrial functions of host cells in support of proliferation and dissemination
Author:
Publisher: Elsevier
ISBN: 0323994113
Category : Science
Languages : en
Pages : 210
Get Book Here
Book Description
Mitochondria and Bacterial Pathogens, Volume 374, Part A. Mitochondria control various processes that are integral to cellular and organismal homeostasis, including Ca2+ fluxes, bioenergetic metabolism, and cell death. Perhaps not surprisingly, multiple pathogenic bacteria have evolved strategies to subvert mitochondrial functions in support of their survival and dissemination. In the IRCMB volume 375, the authors discus different pathogenic mechanisms that converge on the ability of bacteria to control the mitochondrial compartment of host cells. - Collection of articles reporting the role of mitochondria during bacterial infection - Mitochondria, the evolutionary successors of an ancient endosymbiotic prokaryote, occupy a central position in the biology of modern eukaryotic cells - Numerous pathogenic bacteria have evolved strategies to subvert the mitochondrial functions of host cells in support of proliferation and dissemination
Author:
Publisher: Elsevier
ISBN: 0443191247
Category : Science
Languages : en
Pages : 152
Get Book Here
Book Description
Mitochondria and Bacterial Pathogens, Part B, Volume 375 discusses different pathogenic mechanisms that converge on the ability of bacteria to control the mitochondrial compartment of host cells. Chapters in this new release include Interaction between host cell mitochondria and Coxiella Burnetii, Control of mitochondrial functions by Pseudomonas aeruginosa in cystic fibrosis, Mitochondrial and bacterial ATP synthase: Structural similarities and divergences to exploit in the battle against M. tuberculosis, Role of mitochondria in the enteropathogenic Escherichia coli disease, Mitochondria dynamics and antibiotic resistance, and more. - Provides a collection of articles reporting on the role of mitochondria during bacterial infection - Covers Mitochondria, the evolutionary successors of an ancient endosymbiotic prokaryote, occupy a central position in the biology of modern eukaryotic cells - Includes content on numerous pathogenic bacteria and how they have evolved strategies to subvert the mitochondrial functions of host cells in support of proliferation and dissemination
Author: Lorenzo Galluzzi
Publisher: Elsevier
ISBN: 0323994032
Category : Science
Languages : en
Pages : 208
Get Book Here
Book Description
Mitochondria and Bacterial Pathogens, Volume 374, Part A. Mitochondria control various processes that are integral to cellular and organismal homeostasis, including Ca2+ fluxes, bioenergetic metabolism, and cell death. Perhaps not surprisingly, multiple pathogenic bacteria have evolved strategies to subvert mitochondrial functions in support of their survival and dissemination. In the IRCMB volume 375, the authors discus different pathogenic mechanisms that converge on the ability of bacteria to control the mitochondrial compartment of host cells.
Author: Mauro Degli Esposti
Publisher: CRC Press
ISBN: 1351385526
Category : Medical
Languages : en
Pages : 381
Get Book Here
Book Description
Life on earth began with bacteria, which now colonize every corner of the planet. As the ancestors of mitochondria, bacteria are also fundamental for our cells. Most bacteria look alike, but have very different functions. Therefore, knowing the functional profile of bacteria helps understand their impact on our life. This book provides a wealth of information on the functional evolution of bacteria in a novel and coherent way. The book is aimed towards scientists as well as those who are curious about the world of bacteria and their relationships with mitochondria, the powerhouses of our cells, and us.
Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
Get Book Here
Book Description
Author: Nick Lane
Publisher: OUP Oxford
ISBN: 9780191513015
Category : Science
Languages : en
Pages : 370
Get Book Here
Book Description
Mitochondria are tiny structures located inside our cells that carry out the essential task of producing energy for the cell. They are found in all complex living things, and in that sense, they are fundamental for driving complex life on the planet. But there is much more to them than that. Mitochondria have their own DNA, with their own small collection of genes, separate from those in the cell nucleus. It is thought that they were once bacteria living independent lives. Their enslavement within the larger cell was a turning point in the evolution of life, enabling the development of complex organisms and, closely related, the origin of two sexes. Unlike the DNA in the nucleus, mitochondrial DNA is passed down exclusively (or almost exclusively) via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to 'Mitochondrial Eve'. Mitochondria give us important information about our evolutionary history. And that's not all. Mitochondrial genes mutate much faster than those in the nucleus because of the free radicals produced in their energy-generating role. This high mutation rate lies behind our ageing and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer, through their involvement in precipitating cell suicide. Mitochondria, then, are pivotal in power, sex, and suicide. In this fascinating and thought-provoking book, Nick Lane brings together the latest research findings in this exciting field to show how our growing understanding of mitochondria is shedding light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. This understanding is of fundamental importance, both in understanding how we and all other complex life came to be, but also in order to be able to control our own illnesses, and delay our degeneration and death. 'An extraordinary account of groundbreaking modern science... The book abounds with interesting and important ideas.' Mark Ridley, Department of Zoology, University of Oxford
Author: Alexander Tzagoloff
Publisher: Springer
ISBN:
Category : Science
Languages : en
Pages : 488
Get Book Here
Book Description
There are currently a growing number of laboratories actively studying the mechanism by which various biological membranes are assembled. This area of research is still relatively new to biochemists and molecular biologists, but in view of the rapid progress being made, a review of the field at this time is justified. The present volume focuses on the biogenesis of three related membranes. Mitochondria and chloroplasts are semiautonomous organelles whose biogenesis is carried out partly in the external cytoplasm and partly by the organelles themselves. Both membranes are principally concerned with the energy metabolism of the cell, and this commonality of function is reflected in a considerable degree of similarity in their ul trastructure and enzymatic composition. Although the bacterial cell membrane is a much more diversified structure, it also fulfills the basic energy requirements of the cell, and depending on the organism, this can take the form of photosynthesis or oxidative phosphorylation. The addi tional consideration that prokaryotic organisms may, in fact, be the evolu tionary ancestors of mitochondria and chloroplasts, makes it all the more compelling that those interested in biogenesis be aware of new develop ments in each of these three areas. In organizing this book, I felt that the contributors should summarize and bring up to date their own research and review the literature only in sofar as would be necessary to provide the proper perspective for their work.
Author: Sabzali Javadov
Publisher:
ISBN: 9783039363841
Category :
Languages : en
Pages : 434
Get Book Here
Book Description
Mitochondria are subcellular organelles evolved by the endosymbiosis of bacteria with eukaryotic cells. They are the main source of ATP in the cell and engaged in other aspects of cell metabolism and cell function, including the regulation of ion homeostasis, cell growth, redox status, and cell signaling. Due to their central role in cell life and death, mitochondria are also involved in the pathogenesis and progression of human diseases/conditions, including neurodegenerative and cardiovascular disorders, cancer, diabetes, inflammation, and aging. However, despite the increasing number of studies, precise mechanisms whereby mitochondria are involved in the regulation of basic physiological functions, as well as their role in the cell under pathophysiological conditions, remain unknown. A lack of in-depth knowledge of the regulatory mechanisms of mitochondrial metabolism and function, as well as interplay between the factors that transform the organelle from its role in pro-survival to pro-death, have hindered the development of new mitochondria-targeted pharmacological and conditional approaches for the treatment of human diseases. This book highlights the latest achievements in elucidating the role of mitochondria under physiological conditions, in various cell/animal models of human diseases, and in patients.
Author: Lawrence H. Lash
Publisher: Elsevier
ISBN: 1483218619
Category : Science
Languages : en
Pages : 527
Get Book Here
Book Description
Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.
Author: Charles E. Bullerwell
Publisher: Springer Science & Business Media
ISBN: 364222380X
Category : Science
Languages : en
Pages : 481
Get Book Here
Book Description
Mitochondria and chloroplasts are eukaryotic organelles that evolved from bacterial ancestors and harbor their own genomes. The gene products of these genomes work in concert with those of the nuclear genome to ensure proper organelle metabolism and biogenesis. This book explores the forces that have shaped the evolution of organelle genomes and the expression of the genes encoded by them. Some striking examples of trends in organelle evolution explored here are the reduction in genome size and gene coding content observed in most lineages, the complete loss of organelle DNA in certain lineages, and the unusual modes of gene expression that have emerged, such as the extensive and essential mRNA editing that occurs in plant mitochondria and chloroplasts. This book places particular emphasis on the current techniques used to study the evolution of organelle genomes and gene expression.
