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Author:
Publisher:
ISBN:
Category : Brain
Languages : en
Pages : 76
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Book Description
Author:
Publisher:
ISBN:
Category : Brain
Languages : en
Pages : 76
Get Book Here
Book Description
Author: George F. Koob
Publisher: Academic Press
ISBN: 0123869595
Category : Medical
Languages : en
Pages : 351
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Book Description
Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain. - Full-color circuitry diagrams of brain regions implicated in each stage of the addiction cycle - Actual data figures from original sources illustrating key concepts and findings - Introduction to basic neuropharmacology terms and concepts - Introduction to numerous animal models used to study diverse aspects of drug use. - Thorough review of extant work on the neurobiology of addiction
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309439124
Category : Social Science
Languages : en
Pages : 171
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Book Description
Estimates indicate that as many as 1 in 4 Americans will experience a mental health problem or will misuse alcohol or drugs in their lifetimes. These disorders are among the most highly stigmatized health conditions in the United States, and they remain barriers to full participation in society in areas as basic as education, housing, and employment. Improving the lives of people with mental health and substance abuse disorders has been a priority in the United States for more than 50 years. The Community Mental Health Act of 1963 is considered a major turning point in America's efforts to improve behavioral healthcare. It ushered in an era of optimism and hope and laid the groundwork for the consumer movement and new models of recovery. The consumer movement gave voice to people with mental and substance use disorders and brought their perspectives and experience into national discussions about mental health. However over the same 50-year period, positive change in American public attitudes and beliefs about mental and substance use disorders has lagged behind these advances. Stigma is a complex social phenomenon based on a relationship between an attribute and a stereotype that assigns undesirable labels, qualities, and behaviors to a person with that attribute. Labeled individuals are then socially devalued, which leads to inequality and discrimination. This report contributes to national efforts to understand and change attitudes, beliefs and behaviors that can lead to stigma and discrimination. Changing stigma in a lasting way will require coordinated efforts, which are based on the best possible evidence, supported at the national level with multiyear funding, and planned and implemented by an effective coalition of representative stakeholders. Ending Discrimination Against People with Mental and Substance Use Disorders: The Evidence for Stigma Change explores stigma and discrimination faced by individuals with mental or substance use disorders and recommends effective strategies for reducing stigma and encouraging people to seek treatment and other supportive services. It offers a set of conclusions and recommendations about successful stigma change strategies and the research needed to inform and evaluate these efforts in the United States.
Author: Office of the Surgeon General
Publisher: Createspace Independent Publishing Platform
ISBN: 9781974580620
Category :
Languages : en
Pages : 420
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Book Description
All across the United States, individuals, families, communities, and health care systems are struggling to cope with substance use, misuse, and substance use disorders. Substance misuse and substance use disorders have devastating effects, disrupt the future plans of too many young people, and all too often, end lives prematurely and tragically. Substance misuse is a major public health challenge and a priority for our nation to address. The effects of substance use are cumulative and costly for our society, placing burdens on workplaces, the health care system, families, states, and communities. The Report discusses opportunities to bring substance use disorder treatment and mainstream health care systems into alignment so that they can address a person's overall health, rather than a substance misuse or a physical health condition alone or in isolation. It also provides suggestions and recommendations for action that everyone-individuals, families, community leaders, law enforcement, health care professionals, policymakers, and researchers-can take to prevent substance misuse and reduce its consequences.
Author: Stephen Kinzer
Publisher: Henry Holt and Company
ISBN: 1250140447
Category : History
Languages : en
Pages : 320
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Book Description
The bestselling author of All the Shah’s Men and The Brothers tells the astonishing story of the man who oversaw the CIA’s secret drug and mind-control experiments of the 1950s and ’60s. The visionary chemist Sidney Gottlieb was the CIA’s master magician and gentlehearted torturer—the agency’s “poisoner in chief.” As head of the MK-ULTRA mind control project, he directed brutal experiments at secret prisons on three continents. He made pills, powders, and potions that could kill or maim without a trace—including some intended for Fidel Castro and other foreign leaders. He paid prostitutes to lure clients to CIA-run bordellos, where they were secretly dosed with mind-altering drugs. His experiments spread LSD across the United States, making him a hidden godfather of the 1960s counterculture. For years he was the chief supplier of spy tools used by CIA officers around the world. Stephen Kinzer, author of groundbreaking books about U.S. clandestine operations, draws on new documentary research and original interviews to bring to life one of the most powerful unknown Americans of the twentieth century. Gottlieb’s reckless experiments on “expendable” human subjects destroyed many lives, yet he considered himself deeply spiritual. He lived in a remote cabin without running water, meditated, and rose before dawn to milk his goats. During his twenty-two years at the CIA, Gottlieb worked in the deepest secrecy. Only since his death has it become possible to piece together his astonishing career at the intersection of extreme science and covert action. Poisoner in Chief reveals him as a clandestine conjurer on an epic scale.
Author: Mary Torregrossa
Publisher: Academic Press
ISBN: 0128123311
Category : Medical
Languages : en
Pages : 308
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Book Description
Neural Mechanisms of Addiction is the only book available that synthesizes the latest research in the field into a single, accessible resource covering all aspects of how addiction develops and persists in the brain. The book summarizes our most recent understanding on the neural mechanisms underlying addiction. It also examines numerous biobehavioral aspects of addiction disorders, such as reinforcement learning, reward, cognitive dysfunction, stress, and sleep and circadian rhythms that are not covered in any other publication. Readers with find the most up-to-date information on which to build a foundation for their future research in this expanding field. Combining chapters from leading researchers and thought leaders, this book is an indispensable guide for students and investigators engaged in addiction research. - Transcends multiple neural, neurochemical and behavioral domains - Summarizes advances in the field of addiction research since the advent of optogenetics - Discusses the most current, leading theories of addiction, including molecular mechanisms and dopamine mechanisms
Author: Bertha Madras
Publisher: Elsevier
ISBN: 0124186858
Category : Psychology
Languages : en
Pages : 625
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Book Description
Drug use and abuse continues to thrive in contemporary society worldwide and the instance and damage caused by addiction increases along with availability. The Effects of Drug Abuse on the Human Nervous System presents objective, state-of-the-art information on the impact of drug abuse on the human nervous system, with each chapter offering a specific focus on nicotine, alcohol, marijuana, cocaine, methamphetamine, MDMA, sedative-hypnotics, and designer drugs. Other chapters provide a context for drug use, with overviews of use and consequences, epidemiology and risk factors, genetics of use and treatment success, and strategies to screen populations and provide appropriate interventions. The book offers meaningful, relevant and timely information for scientists, health-care professionals and treatment providers. - A comprehensive reference on the effects of drug addiction on the human nervous system - Focuses on core drug addiction issues from nicotine, cocaine, methamphetamine, alcohol, and other commonly abused drugs - Includes foundational science chapters on the biology of addiction - Details challenges in diagnosis and treatment options
Author: Michael J. Kuhar
Publisher: FT Press
ISBN: 0132542501
Category : Family & Relationships
Languages : en
Pages : 237
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Book Description
"The Addicted Brain" explains clearly and vividly what has been learned about how and why some people become addicted and abuse drugs or other substances, the relatively long-term changes these substances can make in the brain, and the progress being made on treatments.
Author: Hardin B. Jones
Publisher: Cambridge University Press
ISBN: 9780521212472
Category : Medical
Languages : en
Pages : 390
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Book Description
Introduction, sensual drug abuse; The brain, the senses, and pleasure; Action of sensual drugs; Hazards of sensual drugs; Addiction and dependency; Sexual deprivation; Drug abuse among American soldiers in Southeast Asia; Rehabilitation; Mind expansion; Marijuana; Effect of drugs on mental state; Fate of Marijuana in the body; Some information about opiates; Drug use among patients in treatment clinics; Some observable signs and symptoms of drug use; Rehabilitation of sexual functioning as an incentive to stop drug use; US Senate hearings on world drug traffic; US Senate hearings on marijuana and hashish; THC: two animal studies; Cannabis seizures; Mortality rate and drug abuse.
Author: Margareta Hammarlund-Udenaes
Publisher: Springer Science & Business Media
ISBN: 1461491053
Category : Medical
Languages : en
Pages : 737
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Book Description
The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics are dynamic and often changed by disease/trauma. Knowledge of all these factors and their interplay in different conditions is of utmost importance for proper CNS drug development and disease treatment. In recent years much information has become available for a better understanding of the many factors important for CNS drug delivery and how they interact to affect drug action. This book describes small and large drug delivery to the brain with an emphasis on the physiology of the BBB and the principles and concepts for drug delivery across the BBB and distribution within the brain. It contains methods descriptions for studying drug delivery, routes and approaches of administering drugs into the brain, the influence of disease, and drug industry perspectives. Therewith, it contributes to an in-depth understanding of the interplay between brain (patho)-physiology and drug characteristics. Furthermore, the content is designed to be both cutting-edge and educational, so that the book can be used in high-level training of academic and industry scientists with full references to original publications.
