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Author: Angela Casini
Publisher: Royal Society of Chemistry
ISBN: 1788017676
Category : Science
Languages : en
Pages : 370
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Book Description
Metal-based anticancer drugs are among the most successful therapeutic agents, as evidenced by the frequent prescription of selected platinum and arsenic compounds to patients. Metal-based Anticancer Agents covers the interdisciplinary world of inorganic drug discovery and development by introducing the most prominent compound classes based on different transition metals, discussing emerging concepts and enabling methods, as well as presenting key pre-clinical and clinical aspects. Recent progress on the unique features of next-generation targeted metal-based anticancer agents, including supramolecular coordination complexes used for both therapy and drug delivery, promise a bright future beyond the benefits of pure cytotoxic activity. With contributions from global leaders in the field, this book will serve as a useful reference to established researchers as well as a practical guide to those new to metallodrugs, and postgraduate students of medicinal chemistry and metallobiology.
Author: Angela Casini
Publisher: Royal Society of Chemistry
ISBN: 1788017676
Category : Science
Languages : en
Pages : 370
Get Book Here
Book Description
Metal-based anticancer drugs are among the most successful therapeutic agents, as evidenced by the frequent prescription of selected platinum and arsenic compounds to patients. Metal-based Anticancer Agents covers the interdisciplinary world of inorganic drug discovery and development by introducing the most prominent compound classes based on different transition metals, discussing emerging concepts and enabling methods, as well as presenting key pre-clinical and clinical aspects. Recent progress on the unique features of next-generation targeted metal-based anticancer agents, including supramolecular coordination complexes used for both therapy and drug delivery, promise a bright future beyond the benefits of pure cytotoxic activity. With contributions from global leaders in the field, this book will serve as a useful reference to established researchers as well as a practical guide to those new to metallodrugs, and postgraduate students of medicinal chemistry and metallobiology.
Author: D. R. F. West
Publisher: CRC Press
ISBN: 1040294960
Category : Technology & Engineering
Languages : en
Pages : 1124
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Book Description
In this book two distinguished metallurgists have traced the role of metallurgical technology in the creation of the scientific revolution and the formation of the Royal Society.
Author: D A Johnson
Publisher: Royal Society of Chemistry
ISBN: 1847557910
Category : Science
Languages : en
Pages : 274
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Book Description
This book looks at how molecules react, and how the feasibility and outcome of chemical reactions can be predicted. Beginning with an introduction to the concept of an activity series of metals, Metals and Chemical Change then introduces chemical thermodynamics (enthalpy, entropy and free energy) and applies the concept to both inorganic and organic elements. A Case Study on batteries and fuel cells is also included. The accompanying CD-ROM includes video sequences of the reactions of metals with water, acid and aqueous ions, and gives the reader an opportunity to make experimental observations and predictions about chemical behaviour. A comprehensive Data Book of chemical and physical constants is included, along with a set of interactive self-assessment questions. The Molecular World series provides an integrated introduction to all branches of chemistry for both students wishing to specialise and those wishing to gain a broad understanding of chemistry and its relevance to the everyday world and to other areas of science. The books, with their Case Studies and accompanying multi-media interactive CD-ROMs, will also provide valuable resource material for teachers and lecturers. (The CD-ROMs are designed for use on a PC running Windows 95, 98, ME or 2000.)
Author: Sanjay K. Sharma
Publisher: Royal Society of Chemistry
ISBN: 1849738858
Category : Medical
Languages : en
Pages : 382
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Book Description
This book highlights the latest research on dissolved heavy metals in drinking water and their removal.
Author: Reed M. Izatt
Publisher: John Wiley & Sons
ISBN: 111900912X
Category : Science
Languages : en
Pages : 552
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Book Description
The sustainable use of natural resources is an important global challenge, and improved metal sustainability is a crucial goal for the 21st century in order to conserve the supply of critical metals and mitigate the environmental and health issues resulting from unrecovered metals. Metal Sustainability: Global Challenges, Consequences and Prospects discusses important topics and challenges associated with sustainability in metal life cycles, from mining ore to beneficiation processes, to product manufacture, to recovery from end-of-life materials, to environmental and health concerns resulting from generated waste. The broad perspective presented highlights the global interdependence of the many stages of metal life cycles. Economic issues are emphasized and relevant environmental, health, political, industrial and societal issues are discussed. The importance of applying green chemistry principles to metal sustainability is emphasized. Topics covered include: • Recycling and sustainable utilization of precious and specialty metals • Formal and informal recycling from electronic and other high-tech wastes • Global management of electronic wastes • Metal reuse and recycling in developing countries • Effects of toxic and other metal releases on the environment and human health • Effect on bacteria of toxic metal release • Selective recovery of platinum group metals and rare earth metals • Metal sustainability from a manufacturing perspective • Economic perspectives on sustainability, mineral development, and metal life cycles • Closing the Loop – Minerals Industry Issues The aim of this book is to improve awareness of the increasingly important role metals play in our high-tech society, the need to conserve our metal supply throughout the metal life cycle, the importance of improved metal recycling, and the effects that unhindered metal loss can have on the environment and on human health.
Author: Anthony F. Hill
Publisher: Royal Society of Chemistry
ISBN: 9780854046225
Category : Education
Languages : en
Pages : 198
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Book Description
What do a pharmaceutical, polymer and solid state chemist have in common? Organometallic chemistry of course, since progress in their diverse fields has at many times relied on this. It is a discipline which stands at the crossroads of so many branches of chemistry, with industrial applications ranging from the gram to megatonne scale. This book aims to introduce undergraduates to the utility of organotransition metal chemistry, a discipline of importance to scientists and technologists in a variety of industry sectors. The main focus will be on the reactivity of organometallic compounds of the transition metals, supported by discussion of structure and bonding and their implications. The aim, on completion of the course, is that a student will be equipped to recognize the key classes of organometallic compounds, their methods of characterization, possible synthetic routes and anticipated reactivity. Ideal for the needs of undergraduate chemistry students, Tutorial Chemistry Texts is a major series consisting of short, single topic or modular texts concentrating on the fundamental areas of chemistry taught in undergraduate science courses. Each book provides a concise account of the basic principles underlying a given subject, embodying an independent-learning philosophy and including worked examples.
Author: Deborah Zamble
Publisher: Royal Society of Chemistry
ISBN: 1788010582
Category : Science
Languages : en
Pages : 396
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Book Description
Metal ions play key roles in biology. Many are essential for catalysis, for electron transfer and for the fixation, sensing, and metabolism of gases. Others compete with those essential metal ions or have toxic or pharmacological effects. This book is structured around the periodic table and focuses on the control of metal ions in cells. It addresses the molecular aspects of binding, transport and storage that ensure balanced levels of the essential elements. Organisms have also developed mechanisms to deal with the non-essential metal ions. However, through new uses and manufacturing processes, organisms are increasingly exposed to changing levels of both essential and non-essential ions in new chemical forms. They may not have developed defenses against some of these forms (such as nanoparticles). Many diseases such as cancer, diabetes and neurodegeneration are associated with metal ion imbalance. There may be a deficiency of the essential metals, overload of either essential or non-essential metals or perturbation of the overall natural balance. This book is the first to comprehensively survey the molecular nature of the overall natural balance of metal ions in nutrition, toxicology and pharmacology. It is written as an introduction to research for students and researchers in academia and industry and begins with a chapter by Professor R J P Williams FRS.
Author: Robert R Crichton
Publisher: Royal Society of Chemistry
ISBN: 1782623892
Category : Science
Languages : en
Pages : 336
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Book Description
Metal chelators are emerging as versatile tool with many medical applications. Their versatility allows them to be used in chelation therapy for treating diseases caused by toxic and heavy metal poisoning, chelating agents are capable of binding to toxic metal ions to form complex structures which are easily excreted from the body removing them from intracellular or extracellular spaces. In addition, metal chelators can also be applied as contrast agents in MRI scanning. Metal Chelation in Medicine provides a clear and timely perspective on the role of chelating agents in the management of metal intoxications and storage diseases. Written by leaders in the field of chelators, this publication is at the cutting-edge of the subject. It covers a broad range of topics such as the use of metal chelators in non-invasive assessment of brain iron overload, and the treatment of systemic iron overload and neurodegenerative diseases. As such it is particularly valuable to clinicians treating metal poisonings and metal storage diseases. However, it is also a useful text for researchers, industry professionals and university students with a specific interest in medicinal chemistry, chelation, metal ions, imaging and non-invasive techniques.
Author: Nadine M. Piatak
Publisher: Royal Society of Chemistry
ISBN: 1788018877
Category : Science
Languages : en
Pages : 321
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Book Description
This book is a definitive reference on the environmental geochemistry and resource potential of metallurgical slags
Author: Lars Öhrström
Publisher: Royal Society of Chemistry
ISBN: 1788010949
Category : Science
Languages : en
Pages : 234
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Book Description
Pink warships that vanish at dusk, urinary maladies of an emperor, and a gold test for cocaine - behold the chemistry of metal ions as never before. In this book you will learn about the sarcophagus molecule, the Chen-Kao test, and how murderers can be caught blue-handed with the wonders of glowing luminol. You will also meet the hidden chemistry of metal ions in everyday life, from the clever modern devices that measure blood-sugar levels, to the leather on your shoes and chewing gum stuck to their soles. Expect to encounter a fair share of heroes and villains, real and fictional, scientist and layperson. Such characters include an ex-MI5 employee running a hospital ward in London amid falling German V1 rockets, a notorious racing cyclist, a proud butler and the lady who first proposed nuclear fission (it's not who you think it is). With engaging, humorous and intelligent prose, the reader will discover the fascinating back-stories of chemical discoveries and inventions where metal ions have played a major role. Featuring a foreword by popular science communicator Dr Raychelle Burks of St. Edward's University, Texas.
