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Author: C. Klaasen
Publisher: Birkhäuser
ISBN: 3034888473
Category : Science
Languages : en
Pages : 641
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Book Description
The Proceedings of the Fourth International Metallothionein Meeting (MT-97) feature the latest research on metallothionein. The book covers a broad range of topics which provide important information for both basic and clinical investigators. The selected 94 articles in this book are written by the leading scientists in the field around the world. This is an increasingly important, multi-disciplinary area of study that has benefitted from recent advances in concepts and methodologies from other fields.
Author: C. Klaasen
Publisher: Birkhäuser
ISBN: 3034888473
Category : Science
Languages : en
Pages : 641
Get Book Here
Book Description
The Proceedings of the Fourth International Metallothionein Meeting (MT-97) feature the latest research on metallothionein. The book covers a broad range of topics which provide important information for both basic and clinical investigators. The selected 94 articles in this book are written by the leading scientists in the field around the world. This is an increasingly important, multi-disciplinary area of study that has benefitted from recent advances in concepts and methodologies from other fields.
Author: Paolo Zatta
Publisher: World Scientific
ISBN: 9814472379
Category : Medical
Languages : en
Pages : 335
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Book Description
Metallothioneins (MTs) represent a large family of proteins characterized by high heavy metal content (mainly CuII and ZnII) and by an unusual cysteine abundance. They have a powerful protective function in all animal tissues, due most likely to their properties as free radical scavengers protecting against oxidative damage. Moreover, the presence and overexpression of MTs in various pathological conditions, such as metal dyshomeostasis, cell proliferation, neurological disorders, and chemotherapy and radiotherapy resistance, could be used as an important prognostic marker, as a histopathological diagnostic tool, and to follow specific pharmacological treatments.This important book explores the role of MTs in the field of neurological disorders (brain inflammation, Alzheimer's and prion diseases, autism, ALS, etc.), cardiology (cardiomyopathy, atherosclerosis), and oncology (melanoma, prostate and breast cancer), through authoritative contributions and a description of basic biochemical information and paradigmatic pathological events.
Author: Astrid Sigel
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110436272
Category : Science
Languages : en
Pages : 544
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Book Description
These sulfur-rich chelators, being important in metal ion homeostasis, find increasing attention. MILS-5, written by 30 internationally recognized experts, focuses on this hot topic. The reader is supported by about 20 tables, more than 80 illustrations and nearly 2000 references. This book is an essential resource for scientists working in a wide range of disciplines from environmental toxicology and inorganic biochemistry all the way through to physiology and medicine.
Author: Emil Roduner
Publisher: Royal Society of Chemistry
ISBN: 1849739072
Category : Education
Languages : en
Pages : 938
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Book Description
An accessible overview of the underlying physico-chemical and physical principles of nanoscience.
Author: Rene Lontie
Publisher: CRC Press
ISBN: 1351079344
Category : Medical
Languages : en
Pages : 251
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Book Description
These volumes of Copper Proteins and Copper Enzymes are intended to describe the contemporary spectroscopy and other biophysical chemistry now being applied to copper proteins in order to determine the structures of their active sites. Several chapters of the treatise describe the functional understanding which is emerging from the new work. The authors are all major contributors to research progress on copper proteins and the volumes will be found to be definitive and authoritative.
Author:
Publisher: Elsevier
ISBN: 0080496962
Category : Science
Languages : en
Pages : 439
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Book Description
This volume of Methods in Enzymology is a companion to Volume 347 and addresses direct sensing of reactive oxygen species and related free radicals by thiol enzymes and proteins.
Author: Helmut Sies
Publisher: Academic Press
ISBN: 0121822516
Category : Active oxygen
Languages : en
Pages : 440
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Book Description
This volume of Methods in Enzymology is a companion to Volume 347 and addresses direct sensing of reactive oxygen species and related free radicals by thiol enzymes and proteins.
Author: United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Health
Publisher:
ISBN:
Category : Cosmetics
Languages : en
Pages : 540
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Book Description
Author: Lars T. Friberg
Publisher: CRC Press
ISBN: 042952272X
Category : Medical
Languages : en
Pages : 320
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Book Description
Published in 1985: Volume 1: Exposure, Dose and Metabolism, treats analysis of cadmium, its uses and occurrence in the environment, cadmium and metallothionein, normal values in human tissues and fluids, metabolism, and presents a metabolic model for cadmium.
Author: Paolo Zatta
Publisher: World Scientific
ISBN: 9812383980
Category : Medical
Languages : en
Pages : 538
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Book Description
Numerous studies have established a clear connection between neuronal oxidative stress and several neurodegenerative diseases, with consequential damages to lipids, proteins, nucleic acids, etc. In addition, several modifications indicative of oxidative stress have been described in association with neurons, neurofibrillary tangles and senile plaques in Alzheimer's disease, including advanced glycation end products and free carbonyl oxidation.Oxidative damage and antioxidant responses are now well characterized, but sources of damaging free radicals are yet to be fully understood. Evidences of alteration in metal ions metabolism have been reported in various diseases like Alzheimer's, Wilson, Menkes, Prion, Pick, Huntington disease, epilepsy and other pathological events. Thus, metal ions play a pivotal role in neurodegenerative phenomena.Chelation therapy is still in the early days of its development, but research in this area could lead to new products that could revolutionize treatment. Two international conferences on ?Metals and the Brain: From Neurochemistry to Neurodegeneration? (Padova, Italy, 2000 and Fez, Morocco, 2002) were recently held to discuss the role of metal ions in neurophysiopathology. A third will be held in 2005 in Johannesburg, South Africa.This book follows the same train of thought as those conferences, in order to highlight the unquestionable importance of metal ions in the research on the neurophysiopathology of neurodegenerative diseases. The excellent reputation of the scientists who have contributed to this project ensures the quality of the chapters presented here, and hopefully this will help spur new research initiatives in the field, which is still in its infancy.
