Mesoporous Silica Nanoparticle-based Protein Delivery Systems for Biomedical Applications PDF Download
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Author:
Publisher:
ISBN: 9789463321198
Category :
Languages : en
Pages : 142
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Book Description
Author:
Publisher:
ISBN: 9789463321198
Category :
Languages : en
Pages : 142
Get Book Here
Book Description
Author:
Publisher: Academic Press
ISBN: 0128155213
Category : Science
Languages : en
Pages : 226
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Book Description
Cancer Therapy and Diagnosis, Part A, Volume 43 in The Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on Mesoporous silica nanoparticle synthesis, Periodic mesoporous organosilica, Nanovalves and other nanomachine-equipped nanoparticles and controlled release, Two-photon light control and photodynamic therapy, Biodegradable PMO nanoparticles, Cationic mesoporous silica and protein delivery, Drug loading, stimuli-responsive delivery and cancer treatment, Animal models and cancer therapy, siRNA delivery and TWIST shutdown for ovarian cancer treatment, and TBC (mesoporous silica nanoparticles and cancer therapy or biodistribution of MSN). Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in The Enzymes series Updated release includes the latest information on Cancer Therapy and Diagnosis
Author: Yu Chen
Publisher: Springer
ISBN: 3662486229
Category : Technology & Engineering
Languages : en
Pages : 100
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Book Description
This thesis reports on essential advances in the design, synthesis and biomedical applications of multifunctional Mesoporous Silica Nanoparticles (MSNs). It provides several examples of multifunctional MSN-based drug delivery nanosystems and demonstrates successful synergistic cancer therapies combining MSNs and high-intensity focused ultrasound. The book will especially be of interest to researchers and graduate students in the fields of biomaterials, biology, chemistry, medicine and the life sciences who are working to develop new methods and technologies to combat cancer.
Author: Zongxi Li
Publisher:
ISBN:
Category :
Languages : en
Pages : 208
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Book Description
The work covered in this thesis focuses on the development of mesoporous silica nanoparticle-based platforms for the controlled delivery of therapeutic agents. The first part of the thesis discusses the physical chemical properties of mesoporous silica nanoparticles, including the studies on their uptake and release capacities and the physical states of the encapsulated cargo molecules using spectroscopic methods. The second part of the thesis describes the organic functionalizations of the mesoporous silica nanoparticles with novel cyclodextrin-based nanogate systems, achieving pH and redox responsive controlled release mechanisms, as well as cargo size selectivity for the release from a dual-loaded system. In the third part of this thesis, several examples of the biomedical applications of the mesoporous silica nanoparticle based drug delivery systems are shown. This includes the in vitro delivery of small interference RNA to shutdown endogenous and exogenous gene expressions in cells using the polyethyleneimine coated nanoparticles, the in vivo delivery of anti-cancer therapeutic to achieve tumor suppression effects on mice models, and the in vivo delivery of anti-microbial therapeutic to achieve animal protection from anthrax lethal toxins. A combination of all these areas of research demonstrate the advancement of the mesoporous silica nanoparticle based drug delivery system towards utilization within living organisms, and realization of medicine on the nanoscale.
Author:
Publisher: Academic Press
ISBN: 9780128151112
Category : Science
Languages : en
Pages : 0
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Book Description
Cancer Therapy and Diagnosis, Part B, Volume 44 in The Enzymes series highlights new advances in the field, with this new volume presenting interesting chapters on Mesoporous silica nanoparticle synthesis, Periodic mesoporous organosilica, Nanovalves and other nanomachine-equipped nanoparticles and controlled release, Two-photon light control and photodynamic therapy, Biodegradable PMO nanoparticles, Cationic mesoporous silica and protein delivery, Drug loading, stimuli-responsive delivery and cancer treatment, Animal models and cancer therapy, siRNA delivery and TWIST shutdown for ovarian cancer treatment, and TBC (mesoporous silica nanoparticles and cancer therapy or biodistribution of MSN).
Author: Yvonne Perrie
Publisher: Pharmaceutical Press
ISBN: 0857110594
Category : Medical
Languages : en
Pages : 257
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Book Description
"Pharmaceutics - Drug delivery and targeting focuses on what pharmacy students really need to know in order to pass exams, providing concise, bulleted information, key points, tips and an all-important self-assessment section which includes MCQs."--Page 4 of cover.
Author: Luigi Pasqua
Publisher: Smithers Rapra
ISBN: 1847355099
Category : Medical
Languages : en
Pages : 182
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Book Description
This book provides an insightful understanding of the mesoporous silica structure and its special properties. The details of synthesis and modification strategies are discussed by reviewing the open literature. The discussion concerning the potential of mesoporous silica in modern biomedical applications will be related to a critical analysis in the field of material science. This book will help the reader rapidly develop the necessary tools to follow the design of the different mesoporous silica-based devices presented in the various studies. The structure of the different devices is examined in detail and the relationship between the structure and the expected activity are discussed. It will also assist in the ability to design new therapeutic devices in a field where the applications seem to be without limits.
Author: Mariela A. Agotegaray
Publisher: Springer
ISBN: 3319501585
Category : Technology & Engineering
Languages : en
Pages : 93
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Book Description
This brief offers a comprehensive discussion of magnetic targeted drug delivery of silica-coated nanodevices. Focusing on the latest trend in pharmaceutical applications of these nanodevices, a multidisciplinary overview is displayed, from synthesis and design to pharmacokenetics, biodistribution and toxicology. Chapters include design of silica-coated magnetic nanodevices; techniques for drug loading with features applicable to biological systems; synthesis, characterization and the assessment of biomedical issues with both in vitro and in vivo experiments. Applications in the treatment of different localized diseases are also addressed in order to present the potential use of these nanosystems as global, commercially available therapeutics.
Author: Amit Singh
Publisher: Royal Society of Chemistry
ISBN: 1788014669
Category : Technology & Engineering
Languages : en
Pages : 376
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Book Description
The increased understanding of molecular aspects associated with chronic diseases, such as cancer and the role of tumor microenvironment, has led to the identification of endogenous and exogenous stimuli that can be exploited to devise “stimuli-responsive” materials for site-specific drug delivery applications. This book provides a comprehensive account on the design, materials chemistry, and application aspects behind these novel stimuli-responsive materials. Setting the scene, the editors open with a chapter addressing the need for smart materials in delivery applications for therapy, imaging and disease diagnosis. The following chapter describes the key physical and chemical aspects of smart materials, from lipids to polymers to hybrid materials, providing the reader with a springboard to delve into the more application oriented chapters that follow. With in-depth coverage of key drug delivery systems such as pH-responsive, temperature responsive, enzyme-responsive and light responsive systems, this book provides a rigorous foundation to the field. A perfect resource for graduate students and newcomers, the closing chapter on regulatory and commercialization challenges also makes the book ideal for those wanting to take the next step towards clinical translation.
Author: David J. Hauss
Publisher: CRC Press
ISBN: 1420017268
Category : Medical
Languages : en
Pages : 370
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Book Description
Oral lipid-based formulations are attracting considerable attention due to their capacity to facilitate gastrointestinal absorption and reduce or eliminate the effect of food on the absorption of poorly water-soluble, lipophilic drugs. Despite the obvious and demonstrated utility of these formulations for addressing a persistent and growing problem