Author: Manashjit Gogoi
Publisher: Springer Nature
ISBN: 9811951411
Category : Medical
Languages : en
Pages : 287
Book Description
This book examines the role of nanobiosensors in point-of-care applications for personalized healthcare and management. It begins by discussing various biomaterials that are used for the development of biosensors in medical diagnostics, and reviews advances in their fabrication and the miniaturization of biosensor devices for lab-on-chip analysis. In turn, it explores the rapidly evolving applications of nanomaterials in the context of biomaterial diagnostics. The book also explores the immense potential of biosensors in medical diagnostics, where they are increasingly being used to detect a wide range of biomolecules and biomarkers. In closing, it discusses the current challenges and outlines the future role of nanobiosensors in the development of next-generation point-of-care applications.
Nanobiosensors for point-of-care medical diagnostics
Author: Manashjit Gogoi
Publisher: Springer Nature
ISBN: 9811951411
Category : Medical
Languages : en
Pages : 287
Book Description
This book examines the role of nanobiosensors in point-of-care applications for personalized healthcare and management. It begins by discussing various biomaterials that are used for the development of biosensors in medical diagnostics, and reviews advances in their fabrication and the miniaturization of biosensor devices for lab-on-chip analysis. In turn, it explores the rapidly evolving applications of nanomaterials in the context of biomaterial diagnostics. The book also explores the immense potential of biosensors in medical diagnostics, where they are increasingly being used to detect a wide range of biomolecules and biomarkers. In closing, it discusses the current challenges and outlines the future role of nanobiosensors in the development of next-generation point-of-care applications.
Publisher: Springer Nature
ISBN: 9811951411
Category : Medical
Languages : en
Pages : 287
Book Description
This book examines the role of nanobiosensors in point-of-care applications for personalized healthcare and management. It begins by discussing various biomaterials that are used for the development of biosensors in medical diagnostics, and reviews advances in their fabrication and the miniaturization of biosensor devices for lab-on-chip analysis. In turn, it explores the rapidly evolving applications of nanomaterials in the context of biomaterial diagnostics. The book also explores the immense potential of biosensors in medical diagnostics, where they are increasingly being used to detect a wide range of biomolecules and biomarkers. In closing, it discusses the current challenges and outlines the future role of nanobiosensors in the development of next-generation point-of-care applications.
Drugs During Pregnancy and Lactation
Author: H. Garbis
Publisher: Elsevier Science
ISBN: 9780444507631
Category : Medical
Languages : en
Pages : 1300
Book Description
The care of pregnant women presents one of the paradoxes of modern medicine. Women usually require little medical intervention during an (uneventful) pregnancy. Conversely, those at high risk of damage to their own health or that of their unborn require the help of appropriate medicinal technology, including drugs. Accordingly, there are two classes of pregnant women, the larger group requires support but not much intervention, while the other needs the full range of diagnostic and therapeutic measures applied in any other branch of medicine. This book presents the current state of knowledge about drugs in pregnancy. In each chapter information is presented separately for two different aspects of the problem seeking a drug appropriate for prescription during pregnancy, and assessing the risk of a drug when exposure has already taken place. Practising clinicians who prescribe medicinal products to women who are, or who may become, pregnant, will find this volume an invaluable reference.
Publisher: Elsevier Science
ISBN: 9780444507631
Category : Medical
Languages : en
Pages : 1300
Book Description
The care of pregnant women presents one of the paradoxes of modern medicine. Women usually require little medical intervention during an (uneventful) pregnancy. Conversely, those at high risk of damage to their own health or that of their unborn require the help of appropriate medicinal technology, including drugs. Accordingly, there are two classes of pregnant women, the larger group requires support but not much intervention, while the other needs the full range of diagnostic and therapeutic measures applied in any other branch of medicine. This book presents the current state of knowledge about drugs in pregnancy. In each chapter information is presented separately for two different aspects of the problem seeking a drug appropriate for prescription during pregnancy, and assessing the risk of a drug when exposure has already taken place. Practising clinicians who prescribe medicinal products to women who are, or who may become, pregnant, will find this volume an invaluable reference.
Molecular Beacons
Author: Chaoyong James Yang
Publisher: Springer Science & Business Media
ISBN: 3642391095
Category : Science
Languages : en
Pages : 201
Book Description
Molecular Beacons explains working principle of molecular beacons, discusses their design, synthesis, purification and characterization, explores their thermodynamic and kinetic properties, and more importantly, reviews their in vivo and in vitro applications with the emphasis on the design and modification of molecular beacons for in vivo mRNA imaging applications. This book is designed to bring together in a single resource an organized and comprehensive view of molecular beacons and will be a valuable resource for academic, clinical and industrial scientists and graduate students who may consider exploring molecular beacons in their research or practice. Chaoyong James Yang is the Lu Jiaxi Professor of Chemistry at Xiamen University, China. Weihong Tan is a Distinguished Professor of Chemistry and Biomedical Engineering at Hunan University, China and also a University of Florida Distinguished Professor and V. T. and Louis Jackson Professor of Chemistry at the University of Florida, USA.
Publisher: Springer Science & Business Media
ISBN: 3642391095
Category : Science
Languages : en
Pages : 201
Book Description
Molecular Beacons explains working principle of molecular beacons, discusses their design, synthesis, purification and characterization, explores their thermodynamic and kinetic properties, and more importantly, reviews their in vivo and in vitro applications with the emphasis on the design and modification of molecular beacons for in vivo mRNA imaging applications. This book is designed to bring together in a single resource an organized and comprehensive view of molecular beacons and will be a valuable resource for academic, clinical and industrial scientists and graduate students who may consider exploring molecular beacons in their research or practice. Chaoyong James Yang is the Lu Jiaxi Professor of Chemistry at Xiamen University, China. Weihong Tan is a Distinguished Professor of Chemistry and Biomedical Engineering at Hunan University, China and also a University of Florida Distinguished Professor and V. T. and Louis Jackson Professor of Chemistry at the University of Florida, USA.
Electrochemical DNA Biosensors
Author: Mehmet Sengun Ozsoz
Publisher: CRC Press
ISBN: 9814241776
Category : Science
Languages : en
Pages : 568
Book Description
This book focuses on the basic electrochemical applications of DNA in various areas, from basic principles to the most recent discoveries. The book comprises theoretical and experimental analysis of various properties of nucleic acids, research methods, and some promising applications. The topics discussed in the book include electrochemical detection of DNA hybridization based on latex/gold nanoparticle and nanotubes; nanomaterial-based electrochemical DNA detection; electrochemical detection of microorganism-based DNA biosensors; gold nanoparticle-based electrochemical DNA biosensors; electrochemical detection of the aptamer-target interaction; nanoparticle-induced catalysis for DNA biosensing; basic terms regarding electrochemical DNA (nucleic acids) biosensors; screen-printed electrodes for electrochemical DNA detection; application of field-effect transistors to label free electrical DNA biosensor arrays; and electrochemical detection of nucleic acids using branched DNA amplifiers.
Publisher: CRC Press
ISBN: 9814241776
Category : Science
Languages : en
Pages : 568
Book Description
This book focuses on the basic electrochemical applications of DNA in various areas, from basic principles to the most recent discoveries. The book comprises theoretical and experimental analysis of various properties of nucleic acids, research methods, and some promising applications. The topics discussed in the book include electrochemical detection of DNA hybridization based on latex/gold nanoparticle and nanotubes; nanomaterial-based electrochemical DNA detection; electrochemical detection of microorganism-based DNA biosensors; gold nanoparticle-based electrochemical DNA biosensors; electrochemical detection of the aptamer-target interaction; nanoparticle-induced catalysis for DNA biosensing; basic terms regarding electrochemical DNA (nucleic acids) biosensors; screen-printed electrodes for electrochemical DNA detection; application of field-effect transistors to label free electrical DNA biosensor arrays; and electrochemical detection of nucleic acids using branched DNA amplifiers.
The Missions of James, Peter, and Paul
Author: Bruce D. Chilton
Publisher: BRILL
ISBN: 9047414748
Category : Religion
Languages : en
Pages : 552
Book Description
The Missions of James, Peter, and Paul investigates the nature, diversity, and relationship of three early and important expressions of Judaic Christianity. It is the conviction of the contributors that the Judaic origins of the Christian movement have not been sufficiently understood in both ecclesiastical and academic circles. Comparison with contemporary Judaism is foundational and leads to the question that guides discussion: How did James relate to such prominent figures as Peter and Paul? Given James' own eminence, those relationships must have been hallmarks of his own stance and status, and they open the prospect that we might delineate James' theological perspective more precisely than otherwise possible by means of this contrast with Peter and Paul. That is the reason for the division of the present volume into two parts. The Missions of James, Peter, and Paul is presented in two parts: James and Peter, and James Paul. Several studies investigate the literary and archaeological evidence that clarifies the world in which James, Peter, and Paul lived, while other studies probe exegetical and theological aspects of the discussion.
Publisher: BRILL
ISBN: 9047414748
Category : Religion
Languages : en
Pages : 552
Book Description
The Missions of James, Peter, and Paul investigates the nature, diversity, and relationship of three early and important expressions of Judaic Christianity. It is the conviction of the contributors that the Judaic origins of the Christian movement have not been sufficiently understood in both ecclesiastical and academic circles. Comparison with contemporary Judaism is foundational and leads to the question that guides discussion: How did James relate to such prominent figures as Peter and Paul? Given James' own eminence, those relationships must have been hallmarks of his own stance and status, and they open the prospect that we might delineate James' theological perspective more precisely than otherwise possible by means of this contrast with Peter and Paul. That is the reason for the division of the present volume into two parts. The Missions of James, Peter, and Paul is presented in two parts: James and Peter, and James Paul. Several studies investigate the literary and archaeological evidence that clarifies the world in which James, Peter, and Paul lived, while other studies probe exegetical and theological aspects of the discussion.
Detection of Non-Amplified Genomic DNA
Author: Giuseppe Spoto
Publisher: Springer Science & Business Media
ISBN: 940071226X
Category : Science
Languages : en
Pages : 320
Book Description
This book offers an overview of state-of-the-art in non amplified DNA detection methods and provides chemists, biochemists, biotechnologists and material scientists with an introduction to these methods. In fact all these fields have dedicated resources to the problem of nucleic acid detection, each contributing with their own specific methods and concepts. This book will explain the basic principles of the different non amplified DNA detection methods available, highlighting their respective advantages and limitations. Non-amplified DNA detection can be achieved by adopting different techniques. Such techniques have allowed the commercialization of innovative platforms for DNA detection that are expected to break into the DNA diagnostics market. The enhanced sensitivity required for the detection of non amplified genomic DNA has prompted new strategies that can achieve ultrasensitivity by combining specific materials with specific detection tools. Advanced materials play multiple roles in ultrasensitive detection. Optical and electrochemical detection tools are among the most widely investigated to analyze non amplified nucleic acids. Biosensors based on piezoelectric crystal have been also used to detect unamplified genomic DNA. The main scientific topics related to DNA diagnostics are discussed by an outstanding set of authors with proven experience in this field.
Publisher: Springer Science & Business Media
ISBN: 940071226X
Category : Science
Languages : en
Pages : 320
Book Description
This book offers an overview of state-of-the-art in non amplified DNA detection methods and provides chemists, biochemists, biotechnologists and material scientists with an introduction to these methods. In fact all these fields have dedicated resources to the problem of nucleic acid detection, each contributing with their own specific methods and concepts. This book will explain the basic principles of the different non amplified DNA detection methods available, highlighting their respective advantages and limitations. Non-amplified DNA detection can be achieved by adopting different techniques. Such techniques have allowed the commercialization of innovative platforms for DNA detection that are expected to break into the DNA diagnostics market. The enhanced sensitivity required for the detection of non amplified genomic DNA has prompted new strategies that can achieve ultrasensitivity by combining specific materials with specific detection tools. Advanced materials play multiple roles in ultrasensitive detection. Optical and electrochemical detection tools are among the most widely investigated to analyze non amplified nucleic acids. Biosensors based on piezoelectric crystal have been also used to detect unamplified genomic DNA. The main scientific topics related to DNA diagnostics are discussed by an outstanding set of authors with proven experience in this field.
Point-of-care testing
Author: Peter Luppa
Publisher: Springer
ISBN: 3662544970
Category : Medical
Languages : en
Pages : 451
Book Description
The underlying technology and the range of test parameters available are evolving rapidly. The primary advantage of POCT is the convenience of performing the test close to the patient and the speed at which test results can be obtained, compared to sending a sample to a laboratory and waiting for results to be returned. Thus, a series of clinical applications are possible that can shorten the time for clinical decision-making about additional testing or therapy, as delays are no longer caused by preparation of clinical samples, transport, and central laboratory analysis. Tests in a POC format can now be found for many medical disciplines including endocrinology/diabetes, cardiology, nephrology, critical care, fertility, hematology/coagulation, infectious disease and microbiology, and general health screening. Point-of-care testing (POCT) enables health care personnel to perform clinical laboratory testing near the patient. The idea of conventional and POCT laboratory services presiding within a hospital seems contradictory; yet, they are, in fact, complementary: together POCT and central laboratory are important for the optimal functioning of diagnostic processes. They complement each other, provided that a dedicated POCT coordination integrates the quality assurance of POCT into the overall quality management system of the central laboratory. The motivation of the third edition of the POCT book from Luppa/Junker, which is now also available in English, is to explore and describe clinically relevant analytical techniques, organizational concepts for application and future perspectives of POCT. From descriptions of the opportunities that POCT can provide to the limitations that clinician’s must be cautioned about, this book provides an overview of the many aspects that challenge those who choose to implement POCT. Technologies, clinical applications, networking issues and quality regulations are described as well as a survey of future technologies that are on the future horizon. The editors have spent considerable efforts to update the book in general and to highlight the latest developments, e.g., novel POCT applications of nucleic acid testing for the rapid identification of infectious agents. Of particular note is also that a cross-country comparison of POCT quality rules is being described by a team of international experts in this field.
Publisher: Springer
ISBN: 3662544970
Category : Medical
Languages : en
Pages : 451
Book Description
The underlying technology and the range of test parameters available are evolving rapidly. The primary advantage of POCT is the convenience of performing the test close to the patient and the speed at which test results can be obtained, compared to sending a sample to a laboratory and waiting for results to be returned. Thus, a series of clinical applications are possible that can shorten the time for clinical decision-making about additional testing or therapy, as delays are no longer caused by preparation of clinical samples, transport, and central laboratory analysis. Tests in a POC format can now be found for many medical disciplines including endocrinology/diabetes, cardiology, nephrology, critical care, fertility, hematology/coagulation, infectious disease and microbiology, and general health screening. Point-of-care testing (POCT) enables health care personnel to perform clinical laboratory testing near the patient. The idea of conventional and POCT laboratory services presiding within a hospital seems contradictory; yet, they are, in fact, complementary: together POCT and central laboratory are important for the optimal functioning of diagnostic processes. They complement each other, provided that a dedicated POCT coordination integrates the quality assurance of POCT into the overall quality management system of the central laboratory. The motivation of the third edition of the POCT book from Luppa/Junker, which is now also available in English, is to explore and describe clinically relevant analytical techniques, organizational concepts for application and future perspectives of POCT. From descriptions of the opportunities that POCT can provide to the limitations that clinician’s must be cautioned about, this book provides an overview of the many aspects that challenge those who choose to implement POCT. Technologies, clinical applications, networking issues and quality regulations are described as well as a survey of future technologies that are on the future horizon. The editors have spent considerable efforts to update the book in general and to highlight the latest developments, e.g., novel POCT applications of nucleic acid testing for the rapid identification of infectious agents. Of particular note is also that a cross-country comparison of POCT quality rules is being described by a team of international experts in this field.
Plant Pathology
Author: Christophe Lacomme
Publisher: Humana
ISBN: 9781493926190
Category : Science
Languages : en
Pages : 0
Book Description
The second edition of Plant Pathology: Techniques and Protocols covers diagnostic methods that are currently used in laboratories for a broad range of plant species and matrixes. These include serological and molecular methods that have one or more of the following characteristics: suitability for high-throughput testing, detection of a group of pathogens or of sometimes uncharacterized pathogens, detection and identification of specific pathogens, and high sensitivity. This volume discusses qualitative and quantitative tests, as well as recently developed diagnostic methods. It also provides background information on many pathogens, which are either endemic, non-endemic, or emerging and with different lifecycles that cause diseases of significant importance in a wide variety of hosts. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, background information on pathogens and the disease caused, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Informative and cutting-edge, Plant Pathology: Techniques and Protocols, Second Edition is the perfect book for plant pathologists and molecular biologists who will use this information to test out the latest research in their laboratories.
Publisher: Humana
ISBN: 9781493926190
Category : Science
Languages : en
Pages : 0
Book Description
The second edition of Plant Pathology: Techniques and Protocols covers diagnostic methods that are currently used in laboratories for a broad range of plant species and matrixes. These include serological and molecular methods that have one or more of the following characteristics: suitability for high-throughput testing, detection of a group of pathogens or of sometimes uncharacterized pathogens, detection and identification of specific pathogens, and high sensitivity. This volume discusses qualitative and quantitative tests, as well as recently developed diagnostic methods. It also provides background information on many pathogens, which are either endemic, non-endemic, or emerging and with different lifecycles that cause diseases of significant importance in a wide variety of hosts. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, background information on pathogens and the disease caused, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Informative and cutting-edge, Plant Pathology: Techniques and Protocols, Second Edition is the perfect book for plant pathologists and molecular biologists who will use this information to test out the latest research in their laboratories.
Molecular Identification of Fungi
Author: Youssuf Gherbawy
Publisher: Springer Science & Business Media
ISBN: 3642050425
Category : Science
Languages : en
Pages : 511
Book Description
Fungi enjoy great popularity in pharmaceutical, agricultural, and biotechnological applications. Recent advances in the decipherment of whole fungal genomes promise an acceleration of these trends. This timely book links scientists from different parts of the world who are interested in the molecular identification of fungi combined with the exploration of the fungal biodiversity in different ecosystems. It provides a compendium for scientists who rely on a rapid and reliable detection of fungal specimens in environmental as well as clinical resources in order to ensure the benefit of industrial and clinical applications. Chapters focus on the opportunities and limits of the molecular marker-mediated identification of fungi. Various methods, procedures and strategies are outlined. Furthermore, the book offers an update of the current progress in the development of fungal molecular techniques, and draws attention to potential and associated problems, as well as integrating theory and practice.
Publisher: Springer Science & Business Media
ISBN: 3642050425
Category : Science
Languages : en
Pages : 511
Book Description
Fungi enjoy great popularity in pharmaceutical, agricultural, and biotechnological applications. Recent advances in the decipherment of whole fungal genomes promise an acceleration of these trends. This timely book links scientists from different parts of the world who are interested in the molecular identification of fungi combined with the exploration of the fungal biodiversity in different ecosystems. It provides a compendium for scientists who rely on a rapid and reliable detection of fungal specimens in environmental as well as clinical resources in order to ensure the benefit of industrial and clinical applications. Chapters focus on the opportunities and limits of the molecular marker-mediated identification of fungi. Various methods, procedures and strategies are outlined. Furthermore, the book offers an update of the current progress in the development of fungal molecular techniques, and draws attention to potential and associated problems, as well as integrating theory and practice.
Modulating Gene Expression
Author: Aditi Singh
Publisher: BoD – Books on Demand
ISBN: 1838806962
Category : Medical
Languages : en
Pages : 136
Book Description
RNA interference (RNAi) is a widely used technology for gene silencing and has become a key tool in a myriad of research and lead discoveries. In recent years, the mechanism of RNAi agents has been well investigated, and the technique has been optimized for better effectiveness and safety. On the other hand, the clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9/gRNA system is a recent, novel, targeted genome-editing technique derived from the bacterial immune system. Recent advances in gene-editing research and technologies have enabled the CRISPR Cas9 system to become a popular tool for sequence-specific gene editing to correct and modify eukaryotic systems. In this book, we will focus on the mechanisms, applications, regulations (their pros and cons), and various ways in which RNAi-based methods and CRIPSR-Cas9 technology have stimulated the modulation of gene expression, thereby making them a promising therapeutic tool to treat and prevent complex diseases and disorders.
Publisher: BoD – Books on Demand
ISBN: 1838806962
Category : Medical
Languages : en
Pages : 136
Book Description
RNA interference (RNAi) is a widely used technology for gene silencing and has become a key tool in a myriad of research and lead discoveries. In recent years, the mechanism of RNAi agents has been well investigated, and the technique has been optimized for better effectiveness and safety. On the other hand, the clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9/gRNA system is a recent, novel, targeted genome-editing technique derived from the bacterial immune system. Recent advances in gene-editing research and technologies have enabled the CRISPR Cas9 system to become a popular tool for sequence-specific gene editing to correct and modify eukaryotic systems. In this book, we will focus on the mechanisms, applications, regulations (their pros and cons), and various ways in which RNAi-based methods and CRIPSR-Cas9 technology have stimulated the modulation of gene expression, thereby making them a promising therapeutic tool to treat and prevent complex diseases and disorders.