Mechanisms of Vessel Development: From a Primitive Draft to a Mature Vasculature PDF Download
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Author: Tullio Genova
Publisher: Frontiers Media SA
ISBN: 2889713350
Category : Science
Languages : en
Pages : 198
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Book Description
Author: Tullio Genova
Publisher: Frontiers Media SA
ISBN: 2889713350
Category : Science
Languages : en
Pages : 198
Get Book Here
Book Description
Author: Derek J. Chadwick
Publisher: John Wiley & Sons
ISBN: 0470319429
Category : Science
Languages : en
Pages : 260
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Book Description
The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, including tissue and organ growth and regeneration. It is also part of the pathology of tumour formation and certain inflammatory conditions. In recent years, comprehension of the molecular genetics of blood vessel formation has progressed enormously and studies in vertebrate model systems, especially the mouse and the zebrafish, have identified a common set of molecules and processes that are conserved throughout vertebrate embryogenesis while, in addition, highlighting aspects that may differ between different animal groups. The discovery in the past decade of the crucial role of new blood vessel formation for the development of cancers has generated great interest in angiogenesis (the formation of new blood vessels from pre-existing ones), with its major implications for potential cancer-control strategies. In addition, there are numerous situations where therapeutic treatments either require or would be assisted by vasculogenesis (the de novo formation of blood vessels). In particular, post-stroke therapies could include treatments that stimulate neovascularization of the affected tissues. The development of such treatments, however, requires thoroughly understanding the developmental properties of endothelial cells and the basic biology of blood vessel formation. While there are many books on angiogenesis, this unique book focuses on exactly this basic biology and explores blood vessel formation in connection with tissue development in a range of animal models. It includes detailed discussions of relevant cell biology, genetics and embryogenesis of blood vessel formation and presents insights into the cross-talk between developing blood vessels and other tissues. With contributions from vascular biologists, cell biologists and developmental biologists, a comprehensive and highly interdisciplinary volume is the outcome.
Author: Robert J. Tomanek
Publisher: Springer Science & Business Media
ISBN: 1461201098
Category : Science
Languages : en
Pages : 292
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Book Description
The overall scope of this new series will be to evolve an understanding of the genetic basis of (1) how early mesoderm commits to cells of a heart lineage that progressively and irreversibly assemble into a segmented, primary heart tube that can be remodeled into a four-chambered organ, and (2) how blood vessels are derived and assembled both in the heart and in the body. Our central aim is to establish a four-dimensional, spatiotemporal foundation for the heart and blood vessels that can be genetically dissected for function and mechanism. Since Robert DeHaan's seminal chapter "Morphogenesis of the Vertebrate Heart" published in Organogenesis (Holt Rinehart & Winston, NY) in 1965, there have been surprisingly few books devoted to the subject of cardiovascular mor phogenesis, despite the enormous growth of interest that occurred nationally and internationally. Most writings on the subject have been scholarly compilations of the proceedings of major national or international symposia or multiauthored volumes, often without a specific theme. What is missing are the unifying concepts that can make sense out of a burgeoning database of facts. The Editorial Board of this new series believes the time has come for a book series dedicated to cardio vascular morphogenesis that will serve not only as an important archival and didac tic reference source for those who have recently come into the field but also as a guide to the evolution of afield that is clearly coming of age.
Author: Dan Simionescu
Publisher: BoD – Books on Demand
ISBN: 9533078820
Category : Medical
Languages : en
Pages : 242
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Book Description
Vasculogenesis is the process of new blood vessel formation during embryonic development of the cardiovascular system. This is followed by formation of a vascular tree and finally the cardiovascular system with the myriad of blood vessels that nourish all tissues and organs. Angiogenesis, on the other hand is the process by which new blood vessels take shape from existing blood vessels by "sprouting" of endothelial cells thus expanding the vascular tree. Both scenarios are based on activation, migration, proliferation and maturation of unique precursor cells. The study of blood vessel formation is an essential component of embryonic development, congenital malformations, degenerative diseases, inflammation and cancer and thus has widespread appeal to the biomedical field. Moreover, scientists are now harnessing this information for the purpose of building living blood vessel substitutes for replacement of diseased arteries and veins. This book highlights novel advances in the field of vasculogenesis and angiogenesis, including embryogenesis and development, regulation of progenitor cells, cancer and blood vessel regeneration. We consider this book a good initial source of information for graduate students, medical students and scientists interested in the intricacies of blood vessel formation, maturation, disease and replacement.
Author: Richard N. Feinberg
Publisher: S. Karger AG (Switzerland)
ISBN:
Category : Medical
Languages : en
Pages : 208
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Book Description
Author: Domenico Ribatti
Publisher: Academic Press
ISBN: 0128140216
Category : Science
Languages : en
Pages : 130
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Book Description
In Vivo Models to Study Angiogenesis provides the latest information and an overview of the most common assays for studying angiogenesis in vivo. Under physiological conditions, angiogenesis is tightly controlled, whereas increased production of angiogenic stimuli and/or reduced production of angiogenic inhibitors leads to abnormal neovascularization, such as occurs in cancer, chronic inflammatory disease, diabetic retinopathy, macular degeneration and cardiovascular disorders. Several genetic and epigenetic mechanisms are involved in the early development of the vascular system. This book presents the latest information from the extensive literature and research available. Evidence is now emerging that blood vessels themselves have the ability to provide instructive regulatory signals to surrounding non-vascular target cells during organ development. Thus, endothelial cell signaling is currently believed to promote fundamental cues for cell fate specification, embryo patterning, organ differentiation and postnatal tissue remodeling. - Provides information on the most common assays to study angiogenesis in vivo - Presents an ideal reference for those interested in angiogenesis as a normal and vital process in growth and development - Covers wound healing, the formation of granulation tissue, and the transition of tumors from benign to malignant
Author: István Rusznyák
Publisher: Elsevier
ISBN: 1483185974
Category : Medical
Languages : en
Pages : 973
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Book Description
Lymphatics and Lymph Circulation: Physiology and Pathology is a comprehensive account of the physiology and pathology of lymphatics and lymph circulation, with emphasis on the question of lymph flow as well as the problems of capillary filtration and diffusion in the connective tissue. These intricate processes are explained from a uniform point of view. Comprised of 27 chapters, this book begins with a discussion on the origin and architecture of the lymphatic system, paying particular attention to the discovery of lymphatics and lymph circulation; the phylogenesis and ontogenesis of lymphatics; and general and special anatomy of the lymphatic system. The second part explores the general physiology and pathology of the lymphatic system and includes chapters dealing with the role of the connective tissue in lymph formation; absorption into lymph capillaries; filtration and absorption through serous membranes; and lymph flow and composition. The remaining chapters consider the central nervous system and other organs such as the heart, lung, liver, kidney, and pancreas. This monograph will be useful for students, practitioners, and researchers in physiology and pathology.
Author:
Publisher: Academic Press
ISBN: 0123944104
Category : Science
Languages : en
Pages : 385
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Book Description
This new volume of Current Topics in Developmental Biology covers the area of mechanisms in regeneration. With an international board of authors, it provides a comprehensive set of reviews covering such topics as control of growth during regeneration, skeletal muscle degeneration and regeneration in mammals and flies, and suppression of regeneration in mammals. - Covers the area of mechanisms in regeneration - International board of authors - Provides a comprehensive set of reviews
Author: Joseph R. Geraci
Publisher: National Aquarium in Baltimore
ISBN: 0977460908
Category : Marine mammals
Languages : en
Pages : 386
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Book Description
Comprehensive manual for understanding and carrying out marine mammal rescue activities for stranded seals, manatees, dolphins, whales, or sea otters.
Author: Wilbert S. Aronow
Publisher: Academic Press
ISBN: 0128026057
Category : Science
Languages : en
Pages : 246
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Book Description
Translational Research in Coronary Artery Disease: Pathophysiology to Treatment covers the entire spectrum of basic science, genetics, drug treatment, and interventions for coronary artery disease. With an emphasis on vascular biology, this reference fully explains the fundamental aspects of coronary artery disease pathophysiology. Included are important topics, including endothelial function, endothelial injury, and endothelial repair in various disease states, vascular smooth muscle function and its interaction with the endothelium, and the interrelationship between inflammatory biology and vascular function. By providing this synthesis of current research literature, this reference allows the cardiovascular scientist and practitioner to access everything they need from one source. - Provides a concise summary of recent developments in coronary and vascular research, including previously unpublished data - Summarizes in-depth discussions of the pathobiology and novel treatment strategies for coronary artery disease - Provides access to an accompanying website that contains photos and videos of noninvasive diagnostic modalities for evaluation of coronary artery disease
