Matrix-assisted Laser Desorption/ionization and Ion Activation by Fourier-transform Mass Spectroscopy PDF Download
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Author: John Anthony Castoro
Publisher:
ISBN:
Category : Electron-stimulated desorption
Languages : en
Pages : 492
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Book Description
Author: John Anthony Castoro
Publisher:
ISBN:
Category : Electron-stimulated desorption
Languages : en
Pages : 492
Get Book Here
Book Description
Author: John Anthony Castoro
Publisher:
ISBN:
Category : Electron-stimulated desorption
Languages : en
Pages : 0
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Author: Jie Yao
Publisher:
ISBN:
Category : Biomolecules
Languages : en
Pages : 314
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Author: Donald Anthony Barkauskas
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Category :
Languages : en
Pages :
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Author: Steven Travis Fannin
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ISBN:
Category :
Languages : en
Pages : 312
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Author: Markus Knobeler
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ISBN:
Category :
Languages : en
Pages : 181
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Author:
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ISBN:
Category :
Languages : en
Pages : 9
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The recent development of matrix-assisted UV laser desorption (LD) mass spectrometry has made possible the ionization and detection of extremely large molecules (with molecular weights exceeding 100,000 Daltons). This technique has generated enormous interest in the biological community for the direct examination of large peptides and oligonucleotides. Although this matrix-assisted ionization method has been developed and used almost exclusively with time-of-flight (TOF) mass spectrometers, research is currently in progress to demonstrate this technique with trapped ion mass spectrometers, such as Fourier transform ion cyclotron resonance mass spectrometry (FTMS). The potential capabilities of FTMS for wide mass range, high resolution measurement, and ion trapping experiments suggest that this instrumental technique should be useful for the detailed structural characterization of large ions generated by the matrix-assisted technique. We have recently demonstrated that matrix-assisted ultraviolet laser desorption can be successfully used with FTMS for the ionization of small peptides. The objective of this report is to summarize the application and current limitations of matrix-assisted laser desorption FTMS for the characterization of peptides and oligonucleotides at the isomeric level. 4 refs., 3 figs., 2 tabs.
Author: Anissa Wai-Sinn Wong
Publisher:
ISBN:
Category :
Languages : en
Pages : 256
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Author: Touradj Solouki
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ISBN:
Category :
Languages : en
Pages : 362
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Author: Michael Lynn Easterling
Publisher:
ISBN:
Category :
Languages : en
Pages : 580
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