Mathematical Models in Biological Discovery

Mathematical Models in Biological Discovery PDF Author: D.L. Solomon
Publisher: Springer Science & Business Media
ISBN: 3642930573
Category : Mathematics
Languages : en
Pages : 247

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Book Description
When I was asked to help organize an American Association for the Advancement of Science symposium about how mathematical models have con tributed to biology, I agreed immediately. The subject is of immense importance and wide-spread interest. However, too often it is discussed in biologically sterile environments by "mutual admiration society" groups of "theoreticians", many of whom have never seen, and most of whom have never done, an original scientific experiment with the biolog ical materials they attempt to describe in abstract (and often prejudiced) terms. The opportunity to address the topic during an annual meeting of the AAAS was irresistable. In order to try to maintain the integrity ;,f the original intent of the symposium, it was entitled, "Contributions of Mathematical Models to Biological Discovery". This symposium was organized by Daniel Solomon and myself, held during the 141st annual meeting of the AAAS in New York during January, 1975, sponsored by sections G and N (Biological and Medical Sciences) of the AAAS and the North American Regions of the Biometric Society, and supported by grant BMS 75-0280) from the National Science Foundation. What follows in this volume are papers by nine of the participants who not only felt that they had something to say in a symposium entitled, "Contributions of Mathematical Models to Biological Discovery", but who falso were willing to record their ideas in more detail here.

Mathematical Models in Biological Discovery

Mathematical Models in Biological Discovery PDF Author: D.L. Solomon
Publisher: Springer Science & Business Media
ISBN: 3642930573
Category : Mathematics
Languages : en
Pages : 247

Get Book

Book Description
When I was asked to help organize an American Association for the Advancement of Science symposium about how mathematical models have con tributed to biology, I agreed immediately. The subject is of immense importance and wide-spread interest. However, too often it is discussed in biologically sterile environments by "mutual admiration society" groups of "theoreticians", many of whom have never seen, and most of whom have never done, an original scientific experiment with the biolog ical materials they attempt to describe in abstract (and often prejudiced) terms. The opportunity to address the topic during an annual meeting of the AAAS was irresistable. In order to try to maintain the integrity ;,f the original intent of the symposium, it was entitled, "Contributions of Mathematical Models to Biological Discovery". This symposium was organized by Daniel Solomon and myself, held during the 141st annual meeting of the AAAS in New York during January, 1975, sponsored by sections G and N (Biological and Medical Sciences) of the AAAS and the North American Regions of the Biometric Society, and supported by grant BMS 75-0280) from the National Science Foundation. What follows in this volume are papers by nine of the participants who not only felt that they had something to say in a symposium entitled, "Contributions of Mathematical Models to Biological Discovery", but who falso were willing to record their ideas in more detail here.

Mathematical Models in Biology

Mathematical Models in Biology PDF Author: Leah Edelstein-Keshet
Publisher: SIAM
ISBN: 9780898719147
Category : Mathematics
Languages : en
Pages : 629

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Book Description
Mathematical Models in Biology is an introductory book for readers interested in biological applications of mathematics and modeling in biology. A favorite in the mathematical biology community, it shows how relatively simple mathematics can be applied to a variety of models to draw interesting conclusions. Connections are made between diverse biological examples linked by common mathematical themes. A variety of discrete and continuous ordinary and partial differential equation models are explored. Although great advances have taken place in many of the topics covered, the simple lessons contained in this book are still important and informative. Audience: the book does not assume too much background knowledge--essentially some calculus and high-school algebra. It was originally written with third- and fourth-year undergraduate mathematical-biology majors in mind; however, it was picked up by beginning graduate students as well as researchers in math (and some in biology) who wanted to learn about this field.

Mathematical Modeling of Biological Processes

Mathematical Modeling of Biological Processes PDF Author: Avner Friedman
Publisher: Springer
ISBN: 3319083147
Category : Mathematics
Languages : en
Pages : 152

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Book Description
This book on mathematical modeling of biological processes includes a wide selection of biological topics that demonstrate the power of mathematics and computational codes in setting up biological processes with a rigorous and predictive framework. Topics include: enzyme dynamics, spread of disease, harvesting bacteria, competition among live species, neuronal oscillations, transport of neurofilaments in axon, cancer and cancer therapy, and granulomas. Complete with a description of the biological background and biological question that requires the use of mathematics, this book is developed for graduate students and advanced undergraduate students with only basic knowledge of ordinary differential equations and partial differential equations; background in biology is not required. Students will gain knowledge on how to program with MATLAB without previous programming experience and how to use codes in order to test biological hypothesis.

Mathematical Models in Biology

Mathematical Models in Biology PDF Author: Elizabeth Spencer Allman
Publisher: Cambridge University Press
ISBN: 9780521525862
Category : Mathematics
Languages : en
Pages : 388

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Book Description
This introductory textbook on mathematical biology focuses on discrete models across a variety of biological subdisciplines. Biological topics treated include linear and non-linear models of populations, Markov models of molecular evolution, phylogenetic tree construction, genetics, and infectious disease models. The coverage of models of molecular evolution and phylogenetic tree construction from DNA sequence data is unique among books at this level. Computer investigations with MATLAB are incorporated throughout, in both exercises and more extensive projects, to give readers hands-on experience with the mathematical models developed. MATLAB programs accompany the text. Mathematical tools, such as matrix algebra, eigenvector analysis, and basic probability, are motivated by biological models and given self-contained developments, so that mathematical prerequisites are minimal.

A Primer in Mathematical Models in Biology

A Primer in Mathematical Models in Biology PDF Author: Lee A. Segel
Publisher: SIAM
ISBN: 1611972493
Category : Science
Languages : en
Pages : 435

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Book Description
A textbook on mathematical modelling techniques with powerful applications to biology, combining theoretical exposition with exercises and examples.

Mathematical Models for Society and Biology

Mathematical Models for Society and Biology PDF Author: Edward Beltrami
Publisher: Academic Press
ISBN: 0124046932
Category : Social Science
Languages : en
Pages : 281

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Book Description
Mathematical Models for Society and Biology, 2e, is a useful resource for researchers, graduate students, and post-docs in the applied mathematics and life science fields. Mathematical modeling is one of the major subfields of mathematical biology. A mathematical model may be used to help explain a system, to study the effects of different components, and to make predictions about behavior. Mathematical Models for Society and Biology, 2e, draws on current issues to engagingly relate how to use mathematics to gain insight into problems in biology and contemporary society. For this new edition, author Edward Beltrami uses mathematical models that are simple, transparent, and verifiable. Also new to this edition is an introduction to mathematical notions that every quantitative scientist in the biological and social sciences should know. Additionally, each chapter now includes a detailed discussion on how to formulate a reasonable model to gain insight into the specific question that has been introduced. Offers 40% more content – 5 new chapters in addition to revisions to existing chapters Accessible for quick self study as well as a resource for courses in molecular biology, biochemistry, embryology and cell biology, medicine, ecology and evolution, bio-mathematics, and applied math in general Features expanded appendices with an extensive list of references, solutions to selected exercises in the book, and further discussion of various mathematical methods introduced in the book

Mathematical Models for Biological Pattern Formation

Mathematical Models for Biological Pattern Formation PDF Author: Philip K. Maini
Publisher: Springer Science & Business Media
ISBN: 1461301335
Category : Mathematics
Languages : en
Pages : 327

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Book Description
This 121st IMA volume, entitled MATHEMATICAL MODELS FOR BIOLOGICAL PATTERN FORMATION is the first of a new series called FRONTIERS IN APPLICATION OF MATHEMATICS. The FRONTIERS volumes are motivated by IMA pro grams and workshops, but are specially planned and written to provide an entree to and assessment of exciting new areas for the application of mathematical tools and analysis. The emphasis in FRONTIERS volumes is on surveys, exposition and outlook, to attract more mathematicians and other scientists to the study of these areas and to focus efforts on the most important issues, rather than papers on the most recent research results aimed at an audience of specialists. The present volume of peer-reviewed papers grew out of the 1998-99 IMA program on "Mathematics in Biology," in particular the Fall 1998 em phasis on "Theoretical Problems in Developmental Biology and Immunol ogy." During that period there were two workshops on Pattern Formation and Morphogenesis, organized by Professors Murray, Maini and Othmer. James Murray was one of the principal organizers for the entire year pro gram. I am very grateful to James Murray for providing an introduction, and to Philip Maini and Hans Othmer for their excellent work in planning and preparing this first FRONTIERS volume. I also take this opportunity to thank the National Science Foundation, whose financial support of the IMA made the Mathematics in Biology pro gram possible.

Mathematical Models in Biology

Mathematical Models in Biology PDF Author: Valeria Zazzu
Publisher: Springer
ISBN: 3319234978
Category : Mathematics
Languages : en
Pages : 207

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Book Description
This book presents an exciting collection of contributions based on the workshop “Bringing Maths to Life” held October 27-29, 2014 in Naples, Italy. The state-of-the art research in biology and the statistical and analytical challenges facing huge masses of data collection are treated in this Work. Specific topics explored in depth surround the sessions and special invited sessions of the workshop and include genetic variability via differential expression, molecular dynamics and modeling, complex biological systems viewed from quantitative models, and microscopy images processing, to name several. In depth discussions of the mathematical analysis required to extract insights from complex bodies of biological datasets, to aid development in the field novel algorithms, methods and software tools for genetic variability, molecular dynamics, and complex biological systems are presented in this book. Researchers and graduate students in biology, life science, and mathematics/statistics will find the content useful as it addresses existing challenges in identifying the gaps between mathematical modeling and biological research. The shared solutions will aid and promote further collaboration between life sciences and mathematics.

Mathematical Models in Population Biology and Epidemiology

Mathematical Models in Population Biology and Epidemiology PDF Author: Fred Brauer
Publisher: Springer Science & Business Media
ISBN: 1475735162
Category : Science
Languages : en
Pages : 432

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Book Description
The goal of this book is to search for a balance between simple and analyzable models and unsolvable models which are capable of addressing important questions on population biology. Part I focusses on single species simple models including those which have been used to predict the growth of human and animal population in the past. Single population models are, in some sense, the building blocks of more realistic models -- the subject of Part II. Their role is fundamental to the study of ecological and demographic processes including the role of population structure and spatial heterogeneity -- the subject of Part III. This book, which will include both examples and exercises, is of use to practitioners, graduate students, and scientists working in the field.

Dynamics of Mathematical Models in Biology

Dynamics of Mathematical Models in Biology PDF Author: Alessandra Rogato
Publisher: Springer
ISBN: 3319457233
Category : Mathematics
Languages : en
Pages : 148

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Book Description
This volume focuses on contributions from both the mathematics and life science community surrounding the concepts of time and dynamicity of nature, two significant elements which are often overlooked in modeling process to avoid exponential computations. The book is divided into three distinct parts: dynamics of genomes and genetic variation, dynamics of motifs, and dynamics of biological networks. Chapters included in dynamics of genomes and genetic variation analyze the molecular mechanisms and evolutionary processes that shape the structure and function of genomes and those that govern genome dynamics. The dynamics of motifs portion of the volume provides an overview of current methods for motif searching in DNA, RNA and proteins, a key process to discover emergent properties of cells, tissues, and organisms. The part devoted to the dynamics of biological networks covers networks aptly discusses networks in complex biological functions and activities that interpret processes in cells. Moreover, chapters in this section examine several mathematical models and algorithms available for integration, analysis, and characterization. Once life scientists began to produce experimental data at an unprecedented pace, it become clear that mathematical models were necessary to interpret data, to structure information with the aim to unveil biological mechanisms, discover results, and make predictions. The second annual “Bringing Maths to Life” workshop held in Naples, Italy October 2015, enabled a bi-directional flow of ideas from and international group of mathematicians and biologists. The venue allowed mathematicians to introduce novel algorithms, methods, and software that may be useful to model aspects of life science, and life scientists posed new challenges for mathematicians.