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Author: Luigi Preziosi
Publisher: Springer
ISBN: 3319426796
Category : Mathematics
Languages : en
Pages : 332
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Book Description
The aim of these lecture notes is to give an introduction to several mathematical models and methods that can be used to describe the behaviour of living systems. This emerging field of application intrinsically requires the handling of phenomena occurring at different spatial scales and hence the use of multiscale methods.Modelling and simulating the mechanisms that cells use to move, self-organise and develop in tissues is not only fundamental to an understanding of embryonic development, but is also relevant in tissue engineering and in other environmental and industrial processes involving the growth and homeostasis of biological systems. Growth and organization processes are also important in many tissue degeneration and regeneration processes, such as tumour growth, tissue vascularization, heart and muscle functionality, and cardio-vascular diseases.
Author: Luigi Preziosi
Publisher: Springer
ISBN: 3319426796
Category : Mathematics
Languages : en
Pages : 332
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Book Description
The aim of these lecture notes is to give an introduction to several mathematical models and methods that can be used to describe the behaviour of living systems. This emerging field of application intrinsically requires the handling of phenomena occurring at different spatial scales and hence the use of multiscale methods.Modelling and simulating the mechanisms that cells use to move, self-organise and develop in tissues is not only fundamental to an understanding of embryonic development, but is also relevant in tissue engineering and in other environmental and industrial processes involving the growth and homeostasis of biological systems. Growth and organization processes are also important in many tissue degeneration and regeneration processes, such as tumour growth, tissue vascularization, heart and muscle functionality, and cardio-vascular diseases.
Author: Philip Nelson
Publisher: Macmillan Higher Education
ISBN: 1319036902
Category : Science
Languages : en
Pages : 365
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Book Description
Written for intermediate-level undergraduates pursuing any science or engineering major, Physical Models of Living Systems helps students develop many of the competencies that form the basis of the new MCAT2015. The only prerequisite is first-year physics. With the more advanced "Track-2" sections at the end of each chapter, the book can be used in graduate-level courses as well.
Author: Andreas Kremling
Publisher: CRC Press
ISBN: 1466567899
Category : Mathematics
Languages : en
Pages : 382
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Book Description
Drawing on the latest research in the field, Systems Biology: Mathematical Modeling and Model Analysis presents many methods for modeling and analyzing biological systems, in particular cellular systems. It shows how to use predictive mathematical models to acquire and analyze knowledge about cellular systems. It also explores how the models are systematically applied in biotechnology. The first part of the book introduces biological basics, such as metabolism, signaling, gene expression, and control as well as mathematical modeling fundamentals, including deterministic models and thermodynamics. The text also discusses linear regression methods, explains the differences between linear and nonlinear regression, and illustrates how to determine input variables to improve estimation accuracy during experimental design. The second part covers intracellular processes, including enzymatic reactions, polymerization processes, and signal transduction. The author highlights the process–function–behavior sequence in cells and shows how modeling and analysis of signal transduction units play a mediating role between process and function. The third part presents theoretical methods that address the dynamics of subsystems and the behavior near a steady state. It covers techniques for determining different time scales, sensitivity analysis, structural kinetic modeling, and theoretical control engineering aspects, including a method for robust control. It also explores frequent patterns (motifs) in biochemical networks, such as the feed-forward loop in the transcriptional network of E. coli. Moving on to models that describe a large number of individual reactions, the last part looks at how these cellular models are used in biotechnology. The book also explains how graphs can illustrate the link between two components in large networks with several interactions.
Author: Leah Edelstein-Keshet
Publisher: SIAM
ISBN: 9780898719147
Category : Mathematics
Languages : en
Pages : 629
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Book Description
Mathematical Models in Biology is an introductory book for readers interested in biological applications of mathematics and modeling in biology. A favorite in the mathematical biology community, it shows how relatively simple mathematics can be applied to a variety of models to draw interesting conclusions. Connections are made between diverse biological examples linked by common mathematical themes. A variety of discrete and continuous ordinary and partial differential equation models are explored. Although great advances have taken place in many of the topics covered, the simple lessons contained in this book are still important and informative. Audience: the book does not assume too much background knowledge--essentially some calculus and high-school algebra. It was originally written with third- and fourth-year undergraduate mathematical-biology majors in mind; however, it was picked up by beginning graduate students as well as researchers in math (and some in biology) who wanted to learn about this field.
Author: Rudy Slingerland
Publisher: Princeton University Press
ISBN: 1400839114
Category : Science
Languages : en
Pages : 246
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Book Description
A concise guide to representing complex Earth systems using simple dynamic models Mathematical Modeling of Earth's Dynamical Systems gives earth scientists the essential skills for translating chemical and physical systems into mathematical and computational models that provide enhanced insight into Earth's processes. Using a step-by-step method, the book identifies the important geological variables of physical-chemical geoscience problems and describes the mechanisms that control these variables. This book is directed toward upper-level undergraduate students, graduate students, researchers, and professionals who want to learn how to abstract complex systems into sets of dynamic equations. It shows students how to recognize domains of interest and key factors, and how to explain assumptions in formal terms. The book reveals what data best tests ideas of how nature works, and cautions against inadequate transport laws, unconstrained coefficients, and unfalsifiable models. Various examples of processes and systems, and ample illustrations, are provided. Students using this text should be familiar with the principles of physics, chemistry, and geology, and have taken a year of differential and integral calculus. Mathematical Modeling of Earth's Dynamical Systems helps earth scientists develop a philosophical framework and strong foundations for conceptualizing complex geologic systems. Step-by-step lessons for representing complex Earth systems as dynamical models Explains geologic processes in terms of fundamental laws of physics and chemistry Numerical solutions to differential equations through the finite difference technique A philosophical approach to quantitative problem-solving Various examples of processes and systems, including the evolution of sandy coastlines, the global carbon cycle, and much more Professors: A supplementary Instructor's Manual is available for this book. It is restricted to teachers using the text in courses. For information on how to obtain a copy, refer to: http://press.princeton.edu/class_use/solutions.html
Author: Philip Nelson
Publisher: Chiliagon Science
ISBN: 9781737540243
Category : Science
Languages : en
Pages : 492
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Book Description
Award-winning prof brings you from first-year classes to the frontiers of systems and synthetic biology, epidemic modeling, and imaging. Physical Models of Living Systems first develops the frameworks needed to understand modern ideas about inference from data, as they relate to biological physics research. Later chapters develop stochastic simulation as a tool to handle more complex systems, and then dynamical systems theory applied to cellular control networks, both natural and synthetic. Along the way, you'll also see the foundations of revolutionary advances in imaging (superresolution and cryo-electron microscopy), along with epidemic modeling, mechanobiology, excitable media, and more. The text also has significant overlap with competencies covered in the MCAT exam. Dozens of problems at all levels, many of them new in this edition, will help you to gain simulation and data visualization skills useful in any branch of quantitative science research.
Author: Edward Beltrami
Publisher: Academic Press
ISBN: 0124046932
Category : Social Science
Languages : en
Pages : 281
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Book Description
Mathematical Models for Society and Biology, 2e, is a useful resource for researchers, graduate students, and post-docs in the applied mathematics and life science fields. Mathematical modeling is one of the major subfields of mathematical biology. A mathematical model may be used to help explain a system, to study the effects of different components, and to make predictions about behavior. Mathematical Models for Society and Biology, 2e, draws on current issues to engagingly relate how to use mathematics to gain insight into problems in biology and contemporary society. For this new edition, author Edward Beltrami uses mathematical models that are simple, transparent, and verifiable. Also new to this edition is an introduction to mathematical notions that every quantitative scientist in the biological and social sciences should know. Additionally, each chapter now includes a detailed discussion on how to formulate a reasonable model to gain insight into the specific question that has been introduced. - Offers 40% more content – 5 new chapters in addition to revisions to existing chapters - Accessible for quick self study as well as a resource for courses in molecular biology, biochemistry, embryology and cell biology, medicine, ecology and evolution, bio-mathematics, and applied math in general - Features expanded appendices with an extensive list of references, solutions to selected exercises in the book, and further discussion of various mathematical methods introduced in the book
Author: Vladislav Mantic
Publisher: World Scientific
ISBN: 178326411X
Category : Technology & Engineering
Languages : en
Pages : 521
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Book Description
This book provides a representative selection of the most relevant, innovative, and useful mathematical methods and models applied to the analysis and characterization of composites and their behaviour on micro-, meso-, and macroscale. It establishes the fundamentals for meaningful and accurate theoretical and computer modelling of these materials in the future. Although the book is primarily concerned with fibre-reinforced composites, which have ever-increasing applications in fields such as aerospace, many of the results presented can be applied to other kinds of composites. The topics covered include: scaling and homogenization procedures in composite structures, thin plate and wave solutions in anisotropic materials, laminated structures, instabilities, fracture and damage analysis of composites, and highly efficient methods for simulation of composites manufacturing. The results presented are useful in the design, fabrication, testing, and industrial applications of composite components and structures. The book is written by well-known experts in different areas of applied mathematics, physics, and composite engineering and is an essential source of reference for graduate and doctoral students, as well as researchers. It is also suitable for non-experts in composites who wish to have an overview of both the mathematical methods and models used in this area and the related open problems requiring further research.
Author: Alan Garfinkel
Publisher: Springer
ISBN: 3319597310
Category : Mathematics
Languages : en
Pages : 456
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Book Description
This book develops the mathematical tools essential for students in the life sciences to describe interacting systems and predict their behavior. From predator-prey populations in an ecosystem, to hormone regulation within the body, the natural world abounds in dynamical systems that affect us profoundly. Complex feedback relations and counter-intuitive responses are common in nature; this book develops the quantitative skills needed to explore these interactions. Differential equations are the natural mathematical tool for quantifying change, and are the driving force throughout this book. The use of Euler’s method makes nonlinear examples tractable and accessible to a broad spectrum of early-stage undergraduates, thus providing a practical alternative to the procedural approach of a traditional Calculus curriculum. Tools are developed within numerous, relevant examples, with an emphasis on the construction, evaluation, and interpretation of mathematical models throughout. Encountering these concepts in context, students learn not only quantitative techniques, but how to bridge between biological and mathematical ways of thinking. Examples range broadly, exploring the dynamics of neurons and the immune system, through to population dynamics and the Google PageRank algorithm. Each scenario relies only on an interest in the natural world; no biological expertise is assumed of student or instructor. Building on a single prerequisite of Precalculus, the book suits a two-quarter sequence for first or second year undergraduates, and meets the mathematical requirements of medical school entry. The later material provides opportunities for more advanced students in both mathematics and life sciences to revisit theoretical knowledge in a rich, real-world framework. In all cases, the focus is clear: how does the math help us understand the science?
Author: Elizabeth Spencer Allman
Publisher: Cambridge University Press
ISBN: 9780521525862
Category : Mathematics
Languages : en
Pages : 388
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Book Description
This introductory textbook on mathematical biology focuses on discrete models across a variety of biological subdisciplines. Biological topics treated include linear and non-linear models of populations, Markov models of molecular evolution, phylogenetic tree construction, genetics, and infectious disease models. The coverage of models of molecular evolution and phylogenetic tree construction from DNA sequence data is unique among books at this level. Computer investigations with MATLAB are incorporated throughout, in both exercises and more extensive projects, to give readers hands-on experience with the mathematical models developed. MATLAB programs accompany the text. Mathematical tools, such as matrix algebra, eigenvector analysis, and basic probability, are motivated by biological models and given self-contained developments, so that mathematical prerequisites are minimal.
