Lytic Transglycosylases are Responsible for the Production of Peptidoglycan-derived Cytotoxin in Neisseria Gonorrhoeae PDF Download
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Author: Karen Ann Cloud
Publisher:
ISBN:
Category :
Languages : en
Pages : 280
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Book Description
Author: Karen Ann Cloud
Publisher:
ISBN:
Category :
Languages : en
Pages : 280
Get Book Here
Book Description
Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 804
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Book Description
Author: J.-M. Ghuysen
Publisher: Elsevier
ISBN: 0080860877
Category : Science
Languages : en
Pages : 607
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Book Description
Studies of the bacterial cell wall emerged as a new field of research in the early 1950s, and has flourished in a multitude of directions. This excellent book provides an integrated collection of contributions forming a fundamental reference for researchers and of general use to teachers, advanced students in the life sciences, and all scientists in bacterial cell wall research. Chapters include topics such as: Peptidoglycan, an essential constituent of bacterial endospores; Teichoic and teichuronic acids, lipoteichoic acids, lipoglycans, neural complex polysaccharides and several specialized proteins are frequently unique wall-associated components of Gram-positive bacteria; Bacterial cells evolving signal transduction pathways; Underlying mechanisms of bacterial resistance to antibiotics.
Author: Tony Romeo
Publisher: Springer Science & Business Media
ISBN: 3540754180
Category : Medical
Languages : en
Pages : 302
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Book Description
Throughout the biological world, bacteria thrive predominantly in surface-attached, matrix-enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiology and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the descriptive stage, and have begun to provide molecular details of the structural, biochemical, and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various species, but there are also commonalities. In most species, environmental and nutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections. This volume focuses on the biology of biofilms that affect human disease, although it is by no means comprehensive. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental, and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth.
Author: W. Scott Champney
Publisher: Springer Science & Business Media
ISBN: 1588299155
Category : Medical
Languages : en
Pages : 274
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Book Description
This book examines specific techniques which can be used to explore new drug targets and the effectiveness of new antibiotics. By testing new antimicrobial agents and modified existing drugs, the most vulnerable cell processes, such as cell wall and membrane synthesis, DNA replication, RNA transcription and protein synthesis, can be better exploited. This in-depth volume, however, delves even deeper by identifying additional novel cellular targets for these new therapies. The book will provide laboratory investigators with the vital tools they need to test the antimicrobial potential of products and to curb the rise of so many infectious diseases.
Author: Moselio Schaechter
Publisher: Academic Press
ISBN: 0080961282
Category : Science
Languages : en
Pages : 1277
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Book Description
The Desk Encyclopedia of Microbiology, Second Edition is a single-volume comprehensive guide to microbiology for the advanced reader. Derived from the six volume e-only Encyclopedia of Microbiology, Third Edition, it bridges the gap between introductory texts and specialized reviews. Covering topics ranging from the basic science of microbiology to the current "hot" topics in the field, it will be invaluable for obtaining background information on a broad range of microbiological topics, preparing lectures and preparing grant applications and reports. The most comprehensive single-volume source providing an overview of microbiology to non-specialists Bridges the gap between introductory texts and specialized reviews Provides concise and general overviews of important topics within the field making it a helpful resource when preparing for lectures, writing reports, or drafting grant applications
Author: P. Jolles
Publisher: Birkhäuser
ISBN: 9783034899529
Category : Science
Languages : en
Pages : 458
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Book Description
More than seventy years after Fleming's discovery of lysozyme, this enzyme continues to play a crucial role as a model enzyme in protein chemistry, enzymology, crystallography, molecular biology and genetics, immunology and also in evolutionary biology. The classical representative of this widespread enzyme family is the hen egg-white lysozyme. Chicken (c)-type lysozymes have also been characterized in many other animals including mammals, reptiles and invertebrates. Besides this c-type lysozyme, other distinct types, differing on the basis of structural, catalytic and immunological critera, have been described as well, these in birds, phages, bacteria, fungi, invertebrates and plants. The specificity, however, of all these enzymes is the same: they cleave a ß-glycosidic bond between the C-1 of N-acetylmuramic acid and the C-4 of N-acetylglucosamine of the bacterial peptidoglycan. In this volume special emphasis is placed on results obtained during the last ten years. Lysozymes are by no means merely defence or, in certain cases, digestion enzymes. In fact, peptidoglycan fragments released by the lytic action of this enzyme family can trigger the synthesis of immunostimulating or antibacterial substances, and a host of other unexpected, biological reactions may be provoked by lysozymes as well. As Fleming has prophesized: ''We shall hear more about lysozyme''.
Author: Bertram O. Fraser-Reid
Publisher: Springer Science & Business Media
ISBN: 3540361545
Category : Science
Languages : en
Pages : 2847
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Book Description
As a reflection of the quantum leap that has been made in the study of glycostructures, the first edition of this book has been completely revised and updated. The editors give up-to-date information on glycostructures, their chemistry and chemical biology in the form of a completely comprehensive survey. Glycostructures play highly diverse and crucial roles in a myriad of organisms and important systems in biology, physiology, medicine, bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and the chemistry behind them. While many facts remain undiscovered, this MRW has been contributed to by a large number of the world’s leading researchers in the field.
Author: Miguel Vicente
Publisher: Springer Science & Business Media
ISBN: 0306485788
Category : Science
Languages : en
Pages : 275
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Book Description
During the last decade a wealth of new data has arisen from the use of new fluorescent labelling techniques and the sequencing of whole microbial genomes. One important conclusion from these data is that bacterial cells are much more structured than previously thought. The wall and the outer membrane contain topological domains, some proteins localize or move in specific patterns inside the cells, and some genes appear clustered in the chromosome and form conserved evolutionary units. Many of these structures are related to the cell cycle and to the process of cell morphogenesis, two processes that are themselves related to each other. From these observations the dcw gene cluster appears as a phylogenetic trait that is mainly conserved in bacilli. Molecules in Time and Space reviews the data on the formation of subcellular patterns or structures in bacteria, presents observations and hypotheses on the establishment and the maintenance of cell shape, and on the organization of genetic information in the chromosome.
Author: Vishvanath Nene
Publisher: Springer Science & Business Media
ISBN: 3540740422
Category : Science
Languages : en
Pages : 253
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Book Description
Achievements and progress in genome mapping and the genomics of microbes supersede by far those for higher plants and animals, in part due to their enormous economic implication but also smaller genome size. In the post-genomic era, whole genome sequences of animal-associated microbes are providing clues to depicting the genetic basis of the complex host-pathogen relationships and the evolution of parasitism; and to improving methods of controlling pathogens. This volume focuses on a globally important group of intracellular prokaryotic pathogens which affect livestock animals. These include Brucella, Mycobacterium, Anaplasma and Ehrlichia, as well as the protozoan pathogens Cryptosporidium and Theileria, for which genome sequence data is available. Insights from comparative genomics of the microbes described provide clues to the adaptation involved in host-microbe interactions, as well as resources potentially useful for application in future research and product development.
