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Author: Anaïs Chapuy
Publisher:
ISBN:
Category :
Languages : fr
Pages : 116
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Book Description
Le pelliculage polymérique de comprimés est une méthode couramment utilisée dans l’ industrie pharmaceutique car elle peut apporter de nombreuses fonctionnalités aux comprimés auxquels elle est appliquée grâce aux multiples excipients et polymères disponibles : -Libération immédiate : o Masquage de goût, o Amélioration de l'aspect/identification, o Protection du principe actif de la lumière et du milieu extérieur, o Déglutition facilitée, o Dépôt de principe actif à la surface de comprimés.-Libération modifiée : o Libération retardée, o Libération prolongée. Le pelliculage est un procédé complexe car de nombreux paran1ètres peuvent influer sur sa réussite. La connaissance et la maîtrise de ce procédé est essentielle. La régulation de ces paramètres et un exemple de procédé sont développés dans ce document.
Author: Anaïs Chapuy
Publisher:
ISBN:
Category :
Languages : fr
Pages : 116
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Book Description
Le pelliculage polymérique de comprimés est une méthode couramment utilisée dans l’ industrie pharmaceutique car elle peut apporter de nombreuses fonctionnalités aux comprimés auxquels elle est appliquée grâce aux multiples excipients et polymères disponibles : -Libération immédiate : o Masquage de goût, o Amélioration de l'aspect/identification, o Protection du principe actif de la lumière et du milieu extérieur, o Déglutition facilitée, o Dépôt de principe actif à la surface de comprimés.-Libération modifiée : o Libération retardée, o Libération prolongée. Le pelliculage est un procédé complexe car de nombreux paran1ètres peuvent influer sur sa réussite. La connaissance et la maîtrise de ce procédé est essentielle. La régulation de ces paramètres et un exemple de procédé sont développés dans ce document.
Author: Michael Faraday
Publisher:
ISBN:
Category : Gold
Languages : en
Pages : 42
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Book Description
Author: Hiroshi Maruta
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 326
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Book Description
This volume discusses the value of research on tumor suppressor genes and the structure-function relationship of the corresponding proteins. The applicability of these non-peptide molecules to anti-cancer drugs is also taken up; and by focusing on contemporary research issues in the field, the book aims to promote understanding and cooperation between industrial and academic researchers.
Author: Itamar Willner
Publisher: John Wiley & Sons
ISBN: 3527604189
Category : Science
Languages : en
Pages : 492
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Book Description
Medicine, chemistry, physics and engineering stand poised to benefit within the next few years from the ingenuity of complex biological structures invented and perfected by nature over millions of years. This book provides both researchers and engineers as well as students of all the natural sciences a vivid insight into the world of bioelectronics and nature's own nanotechnological treasure chamber.
Author: Nicolay Ferrari
Publisher: John Wiley & Sons
ISBN: 1118537335
Category : Medical
Languages : en
Pages : 576
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Book Description
A comprehensive review of contemporary antisense oligonucleotides drugs and therapeutic principles, methods, applications, and research Oligonucleotide-based drugs, in particular antisense oligonucleotides, are part of a growing number of pharmaceutical and biotech programs progressing to treat a wide range of indications including cancer, cardiovascular, neurodegenerative, neuromuscular, and respiratory diseases, as well as other severe and rare diseases. Reviewing fundamentals and offering guidelines for drug discovery and development, this book is a practical guide covering all key aspects of this increasingly popular area of pharmacology and biotech and pharma research, from the basic science behind antisense oligonucleotides chemistry, toxicology, manufacturing, to safety assessments, the design of therapeutic protocols, to clinical experience. Antisense oligonucleotides are single strands of DNA or RNA that are complementary to a chosen sequence. While the idea of antisense oligonucleotides to target single genes dates back to the 1970's, most advances have taken place in recent years. The increasing number of antisense oligonucleotide programs in clinical development is a testament to the progress and understanding of pharmacologic, pharmacokinetic, and toxicologic properties as well as improvement in the delivery of oligonucleotides. This valuable book reviews the fundamentals of oligonucleotides, with a focus on antisense oligonucleotide drugs, and reports on the latest research underway worldwide. • Helps readers understand antisense molecules and their targets, biochemistry, and toxicity mechanisms, roles in disease, and applications for safety and therapeutics • Examines the principles, practices, and tools for scientists in both pre-clinical and clinical settings and how to apply them to antisense oligonucleotides • Provides guidelines for scientists in drug design and discovery to help improve efficiency, assessment, and the success of drug candidates • Includes interdisciplinary perspectives, from academia, industry, regulatory and from the fields of pharmacology, toxicology, biology, and medicinal chemistry Oligonucleotide-Based Drugs and Therapeutics belongs on the reference shelves of chemists, pharmaceutical scientists, chemical biologists, toxicologists and other scientists working in the pharmaceutical and biotechnology industries. It will also be a valuable resource for regulatory specialists and safety assessment professionals and an important reference for academic researchers and post-graduates interested in therapeutics, antisense therapy, and oligonucleotides.
Author: Canadian Intellectual Property Office. Patent Office
Publisher:
ISBN:
Category : Copyright
Languages : un
Pages : 1404
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Book Description
