Le cancer du sein métastatique de novo chez la femme de moins de 40 ans PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Le cancer du sein métastatique de novo chez la femme de moins de 40 ans PDF full book. Access full book title Le cancer du sein métastatique de novo chez la femme de moins de 40 ans by Amélie François. Download full books in PDF and EPUB format.
Author: Amélie François
Publisher:
ISBN:
Category :
Languages : en
Pages : 98
Get Book Here
Book Description
Contexte. Le cancer du sein chez la femme jeune nécessite une prise en charge spécifique, au vu de ses enjeux sur la fertilité, la génétique et les problèmes psycho-sociaux. Le cancer du sein métastatique (CSM) de novo est peu fréquent avec peu de données disponibles. Méthode. Nous avons évalué la prise en charge et le pronostic des femmes de = 40 ans suivies pour un CSM de novo dans la cohorte nationale multicentrique du programme ESME, regroupant 22 463 patientes traitées pour un cancer du sein entre 2008 et 2016. Toutes les patientes ayant un statut RH (récepteurs hormonaux) et HER2 connu ont été incluses. L'objectif principal était de comparer la survie globale (SG) des femmes de = 40 ans à celles des patientes plus âgées, globalement et dans chaque sous-type tumoral. Résultats. Sur les 5 997 femmes identifiées avec un CSM de novo dans la base de données, 598 (10%) avaient = 40 ans. L'âge médian au diagnostic était de 36 ans. La majorité avait une tumeur RH+/HER2- (n=289; 48.3%); tandis que 207 patientes (34.6%) avaient une tumeur HER2+ et 102 (17.1%) une tumeur HR-/HER2- (triple négative, TN). En comparaison avec les femmes de > 40 ans, les femmes de = 40 ans avaient plus fréquemment des tumeurs de grade III (49% vs 33.8%), HER2+ (34.6% vs 24.3%) et TN (17.1% vs 12.1%), p
Author: Amélie François
Publisher:
ISBN:
Category :
Languages : en
Pages : 98
Get Book Here
Book Description
Contexte. Le cancer du sein chez la femme jeune nécessite une prise en charge spécifique, au vu de ses enjeux sur la fertilité, la génétique et les problèmes psycho-sociaux. Le cancer du sein métastatique (CSM) de novo est peu fréquent avec peu de données disponibles. Méthode. Nous avons évalué la prise en charge et le pronostic des femmes de = 40 ans suivies pour un CSM de novo dans la cohorte nationale multicentrique du programme ESME, regroupant 22 463 patientes traitées pour un cancer du sein entre 2008 et 2016. Toutes les patientes ayant un statut RH (récepteurs hormonaux) et HER2 connu ont été incluses. L'objectif principal était de comparer la survie globale (SG) des femmes de = 40 ans à celles des patientes plus âgées, globalement et dans chaque sous-type tumoral. Résultats. Sur les 5 997 femmes identifiées avec un CSM de novo dans la base de données, 598 (10%) avaient = 40 ans. L'âge médian au diagnostic était de 36 ans. La majorité avait une tumeur RH+/HER2- (n=289; 48.3%); tandis que 207 patientes (34.6%) avaient une tumeur HER2+ et 102 (17.1%) une tumeur HR-/HER2- (triple négative, TN). En comparaison avec les femmes de > 40 ans, les femmes de = 40 ans avaient plus fréquemment des tumeurs de grade III (49% vs 33.8%), HER2+ (34.6% vs 24.3%) et TN (17.1% vs 12.1%), p
Author: Monica Castiglione
Publisher: Springer Science & Business Media
ISBN: 0387751157
Category : Medical
Languages : en
Pages : 483
Get Book Here
Book Description
Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable.
Author: William C. Faquin
Publisher: Springer Nature
ISBN: 3031266625
Category : Medical
Languages : en
Pages : 251
Get Book Here
Book Description
The Second Edition of The Milan System for Reporting Salivary Gland Cytopathology, like the First Edition, represents a collaborative effort by a multidisciplinary group of cytopathologists, surgical pathologists, molecular pathologists, radiologists, and head and neck surgeons. This international group shares the goal of creating a practical and uniform reporting system for salivary gland fine needle aspiration (FNA). This book is organized into six general diagnostic categories: “Non-Diagnostic,” “Non-Neoplastic,” “Atypia of Undetermined Significance (AUS),” “Neoplasm: Benign,” “Neoplasm: Salivary Gland Neoplasm of Uncertain Malignant Potential (SUMP),” “Suspicious for Malignancy,” and “Malignant.” It includes definitions, morphologic criteria, and explanations for each of the diagnostic categories. Specific chapters are dedicated to the application of the latest available ancillary studies, radiologic features of salivary gland lesions, clinical management, and histological considerations including updates from the most recent 5th Edition WHO blue book. The Milan System for Reporting Salivary Gland Cytopathology 2nd Edition represents an essential step towards increasing the overall effectiveness of salivary gland FNA and fostering better communication between clinicians and between institutions to improve overall patient care.
Author: Laszlo Muszbek
Publisher: CRC Press
ISBN: 1000013308
Category : Medical
Languages : en
Pages : 278
Get Book Here
Book Description
First Published in 1987: The book is to give insight into the multisided relationship of hemostatic systems and malignancies and to help biomedical scientists and practicing clinicians obtain a better understanding of cancer research.
Author: Marinos C. Dalakas
Publisher: Butterworth-Heinemann
ISBN: 1483163040
Category : Health & Fitness
Languages : en
Pages : 362
Get Book Here
Book Description
Polymyositis and Dermatomyositis provides extensive information regarding Polymyositis and Dermatomyositis (PM/DM), which is described as a heterogeneous disease complex. This book is divided into four sections: Part I (Clinical Features) covers the classification of PM/DM, details of the clinical presentation, and the disease's association with the other connective tissue disorders and malignancies. Part II (Etiology and Mechanisms) covers advances in the immunopathology and viral etiology of PM/DM along with a frequently recognized entity: inclusion body myositis. Part III (Diagnosis and Treatment) covers the histologic, muscle enzyme histochemical, electron microscopic, and resin histology features of PM/DM along with those electromyographic features that could help make a more accurate diagnosis. Part IV (Overview) summarizes the issues that may not have been clear and highlights differing and unsettled views or present available data. This text is directed to clinicians in private practice or in academic institutions concerned with PM/DM patients, including neurologists, rheumatologists, pediatricians, dermatologists, physiatrists, and neuromuscular investigators. This book is intended as well for neuromuscular pathologists who interpret muscle biopsy specimens and electromyographers who perform EMG studies to help determine the clinical diagnosis. Researchers in immunology and immunopathology of neuromuscular diseases will find discussions in this book invaluable.
Author: Linda Diann Urden
Publisher: Saunders
ISBN:
Category : Medical
Languages : en
Pages : 1242
Get Book Here
Book Description
Focusing on critical care nursing, this full-color text provides an examination of the important aspects of critical care nursing. It is organized in ten units around alterations in body systems.
Author: J. Zander
Publisher: Springer Science & Business Media
ISBN: 3642701922
Category : Medical
Languages : en
Pages : 384
Get Book Here
Book Description
March 23 and 24, 1983 saw the fIrst international symposium held under the auspices of the Wilhelm Vaillant Foundation for the Advancement of Pro phylactic Medicine in the I. Frauenklinik der Ludwig Maximilians Univer sitiit Miinchen. This symposium was concerned with Advances in Early Detection and Treatment of Breast Cancer and brought together patholo gists, gynecologists, and radiologists from Denmark, England, France, Italy, Sweden, Switzerland, the German Democratic Republic, and the Federal Republic of Germany. The fIrst session dealt with problems concerned with the biology, patho genesis, and histopathology of early carcinoma of the breast, with special reference to the clinical aspects. The second session was taken up with topi cal developments in the early diagnosis of breast carcinoma and indicated the present limitations of early diagnosis. In the third session the latest results of the experiences by groups working on the treatment of early carci noma of the breast in France, the United Kingdom, Italy, the United States of America, and the Federal Republic of Germany were discussed. The main emphasis lay on conservative treatment methods with complete or partial preservation of the breast. These vary quite widely. Some of the conclusions presented on the basis of long-term clinical studies must be regarded as signifIcant breakthroughs, and at the stage these have reached they must no longer be overlooked. The symposium has highlighted numerous unsolved problems and made it clear that conflicting opinions abound.
Author: Allen Burke
Publisher: Afip
ISBN:
Category : Medical
Languages : en
Pages : 248
Get Book Here
Book Description
Author: Vincent Cottin
Publisher: Springer
ISBN: 1447124014
Category : Medical
Languages : en
Pages : 623
Get Book Here
Book Description
Orphan Lung Diseases: A Clinical Guide to Rare Lung Disease provides a comprehensive, clinically focused textbook on rare and so-called ‘orphan’ pulmonary diseases. The book is oriented towards the diagnostic approach, including manifestations suggesting the disease, diagnostic criteria, methods of diagnostic confirmation, and differential diagnosis, with an overview of management.
Author: Louis B. Harrison
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781771368
Category : Medical
Languages : en
Pages : 1004
Get Book Here
Book Description
This comprehensive, multidisciplinary text addresses all aspects of head and neck cancer and represents a wide spectrum of specialists, including surgical, radiation, and medical oncologists, dentists, pathologists, radiologists, and nurses. The book focuses on a two-part approach to treatment that maximizes the chance for a cure while maintaining a strong emphasis on quality of life. This Third Edition's updated techniques section includes new radiation techniques such as IMRT and IGRT and new endoscopic and laser surgical techniques. Other highlights include a new chapter on reconstructive techniques; significant updates to all site-specific chapters; updates on chemoprevention and molecular targeting; and discussions of new imaging modalities such as fused PET/CT. A companion Website will offer the fully searchable text with all images.
