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Author: Akio Tani
Publisher: Academic Press
ISBN: 9780443133077
Category : Science
Languages : en
Pages : 0
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Book Description
Lanthanides in Enzymology and Microbiology, a new volume in the Foundations and Frontiers in Enzymology series, offers a discussion of lanthanides and lanthanide-dependent enzyme biology. In this book, global experts consider lanthanide enzymology fundamentals, organismal utilization of lanthanides, distribution and diversity of lanthanide-dependent enzymes, regulation of intracellular levels of lanthanides, gene expression regulation via lanthanides, as well as likely applications of lanthanide binding proteins. Lanthanide-dependent methanol and alcohol dehydrogenase metabolism are considered in both methylotrophs and non-methylotrophs, alongside various application areas, from recovery of rare earth elements to developing lanthanide ion binding peptides and biosynthesis of terpolymers through reverse-oxidation pathways. In providing this deep context and pathways for future research, this book acts as an invaluable resource in this emerging field for researchers and students of biochemistry, biotechnology, and environmental microbiology alike.
Author: Akio Tani
Publisher: Academic Press
ISBN: 9780443133077
Category : Science
Languages : en
Pages : 0
Get Book Here
Book Description
Lanthanides in Enzymology and Microbiology, a new volume in the Foundations and Frontiers in Enzymology series, offers a discussion of lanthanides and lanthanide-dependent enzyme biology. In this book, global experts consider lanthanide enzymology fundamentals, organismal utilization of lanthanides, distribution and diversity of lanthanide-dependent enzymes, regulation of intracellular levels of lanthanides, gene expression regulation via lanthanides, as well as likely applications of lanthanide binding proteins. Lanthanide-dependent methanol and alcohol dehydrogenase metabolism are considered in both methylotrophs and non-methylotrophs, alongside various application areas, from recovery of rare earth elements to developing lanthanide ion binding peptides and biosynthesis of terpolymers through reverse-oxidation pathways. In providing this deep context and pathways for future research, this book acts as an invaluable resource in this emerging field for researchers and students of biochemistry, biotechnology, and environmental microbiology alike.
Author:
Publisher: Academic Press
ISBN: 0128238577
Category : Science
Languages : en
Pages : 276
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Book Description
Methods in Enzymology, Volume 650 continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this new release include Biophysical methods to study lanthanide-protein interactions, Genetically encoded sensors to study lanthanide biology, Spectrophotometric methods to determine the stability constants of lanthanide-macromolecule complexes, Lanthanide-based probes for amino acid modifications, In vitro selection and application of lanthanide-dependent DNAzymes, LRET biosensors for imaging protein interactions in living cells, Synthetic Modeling of the Structure and Function of the Lanthanide-Dependent, MDH Cofactor, EPR spectroscopy of lanthanides, Macromolecular crystallography for f-element complex characterization, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series
Author: Christopher H. Evans
Publisher: Springer Science & Business Media
ISBN: 1468487485
Category : Science
Languages : en
Pages : 453
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Book Description
By a happy coincidence, the completion of this text coincided with the 200th anniversary of the discovery of gadolinite, the mineral with which the lanthanide story begins. For a group of elements which occur in only trace amounts biologically, and which have no known metabolic role, the lanthanides have spawned a surprisingly large biochemicalliterature. Se rious interest in the biochemical properties ofthese elements can be traced to concerns about the safety of radioactive lanthanides toward the end of World War 11. As recent events at Chernobyl indicate, this concern re mains topical. However, the literature on lanthanide biochemistry pre dates the atomic era, beginning with sporadic, medically motivated studies in the latter part of the 19th century. Much of the present biochemical activity involving the lanthanides centers around their ability to provide 2 important information on the interactions of Ca + with macromolecules and with eukafyotic cells. With the increasing industrial use of the lan thanides, their toxicological properties will need to be examined more closely. Rare earth pneumonoconiosis has already been identified as a disease produced by industrial exposure to lanthanides. Several of the biochemical properties of the lanthanides are of relevance to modern medicine. Already cerium-based ointments are used to treat burn wounds, while paramagnetic lanthanides find application in nuclear magnetic res onance imaging. This book is an attempt to collate and to present in reasonable detail existing knowledge of lanthanide biochemistry before the literature be comes unmanageable.
Author: P. Jolles
Publisher: Birkhäuser
ISBN: 9783034899529
Category : Science
Languages : en
Pages : 458
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Book Description
More than seventy years after Fleming's discovery of lysozyme, this enzyme continues to play a crucial role as a model enzyme in protein chemistry, enzymology, crystallography, molecular biology and genetics, immunology and also in evolutionary biology. The classical representative of this widespread enzyme family is the hen egg-white lysozyme. Chicken (c)-type lysozymes have also been characterized in many other animals including mammals, reptiles and invertebrates. Besides this c-type lysozyme, other distinct types, differing on the basis of structural, catalytic and immunological critera, have been described as well, these in birds, phages, bacteria, fungi, invertebrates and plants. The specificity, however, of all these enzymes is the same: they cleave a ß-glycosidic bond between the C-1 of N-acetylmuramic acid and the C-4 of N-acetylglucosamine of the bacterial peptidoglycan. In this volume special emphasis is placed on results obtained during the last ten years. Lysozymes are by no means merely defence or, in certain cases, digestion enzymes. In fact, peptidoglycan fragments released by the lytic action of this enzyme family can trigger the synthesis of immunostimulating or antibacterial substances, and a host of other unexpected, biological reactions may be provoked by lysozymes as well. As Fleming has prophesized: ''We shall hear more about lysozyme''.
Author:
Publisher: Academic Press
ISBN: 0323910866
Category : Science
Languages : en
Pages : 414
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Book Description
Rare-Earth Element Biochemistry: Characterization and Applications of Lanthanide-Binding Biomolecules, Volume 651 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this new release include Spectrophotometric methods to probe the solution chemistry of lanthanide complexes with macromolecules, Determination of affinities of lanthanide-binding proteins using chelator-buffered titrations, Electron Paramagnetic Resonance of Lanthanides, Characterization of lanthanoid binding proteins using NMR spectroscopy, Macromolecular crystallography for f-element complex characterization, Infrared spectroscopy probes ion binding geometries, Predicting lanthanide coordination structures in solution with molecular simulation, and much more. Additional sections cover the Characteristics of Gd(III) spin labels for the study of protein conformations, Lanthanide-based resonance energy transfer biosensors for live-cell applications, Yttrium-86 PET imaging, Aqueous Chemistry of the Smallest Rare Earth: Comprehensive Characterization of Radioactive and Non-radioactive Scandium Complexes for Biological Applications, and In vitro selection and application of lanthanide-dependent DNAzymes. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series
Author: Anna Frances Huff
Publisher:
ISBN: 9780355503258
Category : Electronic dissertations
Languages : en
Pages : 61
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Book Description
Author: C. Anthony
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 458
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Book Description
Author: Joseph A. Cotruvo
Publisher: Elsevier
ISBN: 0323910858
Category : Science
Languages : en
Pages : 412
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Book Description
Spectrophotometric methods to probe the solution chemistry of lanthanide complexes with macromolecules / Gauthier J.-P. Deblonde -- Determination of affinities of lanthanide-binding proteins using chelator-buffered titrations / Joseph A. Mattocks, Jonathan L. Tirsch, and Joseph A. Cotruvo, Jr. -- Electron paramagnetic resonance of lanthanides / Joseph E. McPeak, Sandra S. Eaton, and Gareth R. Eaton -- Characterization of lanthanoid-binding proteins using NMR spectroscopy / Enrico Ravera, Linda Cerofolini, Marco Fragai, Giacomo Parigi, and Claudio Luchinat -- Macromolecular crystallography for f-element complex characterization / Roger M. Pallares, Korey P. Carter, David Faulkner, and Rebecca J. Abergel -- Infrared spectroscopy probes ion binding geometries / Sean C. Edington, Stephanie Liu, and Carlos R. Baiz -- Predicting lanthanide coordination structures in solution with molecular simulation / David C. Cantu -- Characteristics of Gd(III) spin labels for the study of protein conformations / Angeliki Giannoulis, Yasmin Ben-Ishay, and Daniella Goldfarb - Lanthanide-based resonance energy transfer biosensors for live-cell applications / Ha Pham and Lawrence W. Miller -- 86Y PET imaging / Mariane Le Fur and Peter Caravan -- Aqueous chemistry of the smallest rare earth : Comprehensive characterization of radioactive and non-radioactive scandium complexes for biological applications / Brett A. Vaughn, Angus J. Koller, and Eszter Boros -- In vitro selection and application of lanthanide-dependent DNAzymes / Po-Jung Jimmy Huang and Juewen Liu.
Author:
Publisher:
ISBN:
Category : Ecology
Languages : en
Pages : 760
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Book Description
Author: Young Je Yoo
Publisher: Springer
ISBN: 9402410260
Category : Technology & Engineering
Languages : en
Pages : 208
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Book Description
This book provides a comprehensive introduction to all aspects of enzyme engineering, from fundamental principles through to the state-of-the-art in research and industrial applications. It begins with a brief history, describing the milestones of advancement in enzyme science and technology, before going on to cover the fundamentals of enzyme chemistry, the biosynthesis of enzymes and their production. Enzyme stability and the reaction kinetics during enzymatic reactions are presented to show how enzymes function during catalysis and the factors that affect their activity. Methods to improve enzyme performance are also presented, such as cofactor regeneration and enzyme immobilization. The book emphasizes and elaborates on the performance and characteristics of enzymes at the molecular level. Finally, the book presents recent advances in enzyme engineering and some key industrial application of enzymes addressing the present needs of society. This book presents essential information not only for undergraduate and graduate students, but also for researchers in academia and industry, providing a valuable reference for the development of commercial applications of enzyme technology.
