Micro-, Meso- and Macro-Connectomics of the Brain

Micro-, Meso- and Macro-Connectomics of the Brain PDF Author: Henry Kennedy
Publisher: Springer
ISBN: 3319277774
Category : Medical
Languages : en
Pages : 173

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Book Description
This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.

Micro-, Meso- and Macro-Connectomics of the Brain

Micro-, Meso- and Macro-Connectomics of the Brain PDF Author: Henry Kennedy
Publisher: Springer
ISBN: 3319277774
Category : Medical
Languages : en
Pages : 173

Get Book Here

Book Description
This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.

Manual Skills, Handedness, and the Organization of Language in the Brain

Manual Skills, Handedness, and the Organization of Language in the Brain PDF Author: Gregory Króliczak
Publisher: Frontiers Media SA
ISBN: 2889459683
Category :
Languages : en
Pages : 163

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Book Description
Whereas the cerebral specialization for skilled manual actions (praxis) seems closely linked to dominance for language, with both functions left lateralized in the vast majority of humans, the neural correlates of hand preference are still less well understood. Indeed, as a combination of inherited and non-inherited genomic factors (i.e., direct parental and concealed environmental contributions), handedness – in contrast to language – is less likely to have strong genetic indices and clearly lateralized functional organization. What about eye dominance, unimanual and bimanual object manipulation, and gestures, or attentional systems and the related egocentric or allocentric coding of space? Are these different categories functionally and structurally interconnected? Is their development and contribution to task performance linked, even if they are differently lateralized? How are they connected to language learning or its development? In trying to understand these relationships and their neural underpinnings we obtain a new insight into fundamental human behaviors, which depend either on shared or distinct cerebral resources that must, nevertheless, be harmonized by higher-order cerebral processing. In this Research Topic we assembled a dozen of original research contributions, as well as articles with more theoretically-driven perspectives, that directly speak to these issues. Hopefully this work will serve as a foundation for further discussions and will stimulate new research in this fascinating domain.

fMRI

fMRI PDF Author: Stephan Ulmer
Publisher: Springer Science & Business Media
ISBN: 3642343422
Category : Medical
Languages : en
Pages : 320

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Book Description
Over the past two decades, fMRI has evolved into an invaluable clinical tool for routine brain imaging. This book provides a state of the art overview of fMRI and its use in clinical practice. Experts in the field share their knowledge and explain how to overcome diverse potential technical barriers and problems. Starting from the very basics on the origin of the BOLD signal, the book covers technical issues, anatomical landmarks, the full range of clinical applications, methods of statistical analysis, and special issues in various clinical fields. Comparisons are made with other brain mapping techniques, such as DTI, PET, TMS, EEG, and MEG, and their combined use with fMRI is also discussed. Since the first edition, original chapters have been updated and new chapters added, covering both novel aspects of analysis and further important clinical applications.

The Lateralized Brain

The Lateralized Brain PDF Author: Sebastian Ocklenburg
Publisher: Academic Press
ISBN: 012803453X
Category : Science
Languages : en
Pages : 383

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Book Description
The Lateralized Brain: The Neuroscience and Evolution of Hemispheric Asymmetries is an up-to-date teaching resource for neuroscience faculty members that teach courses concerning hemispheric asymmetries. The book provides students with all relevant information on the subject, while also giving aspiring researchers in the field an up-to-date overview of relevant, previous work. It is ideal for courses on hemispheric asymmetries, that is, the functional or structural differences between the left and the right hemispheres of the brain, and also highlights how the widespread use of modern neuroimaging techniques, such as fMRI and DTI has completely changed the way hemispheric asymmetries are currently investigated. According to the preface, the main aim of The Lateralized Brain is to provide "an up-to-date teaching resource on hemispheric asymmetries ... [and] to introduce undergraduate students of all levels to the fascinating topics of hemispheric asymmetries" (p. xv)... (Sebastian Ocklenburg and Onur Güntürkün) have succeeded admirably in their stated aim and are to be congratulated on undertaking the mammoth task they set themselves. They can be proud of what they have accomplished.~ Alan A. Beaton, Department of Psychology, Swansea University, Swansea, UK, in Laterality: Asymmetries of Body, Brain and Cognition, July, 2018. - Includes references to key articles, books, protocols and online resources for additional, detailed study - Presents classic studies that helped define the field - Covers key concepts and methods that are explained in separate call out boxes for quick overview - Provides introductory short stories (e.g. classic clinical cases) as a starting point for each chapter

Latent Curve Models

Latent Curve Models PDF Author: Kenneth A. Bollen
Publisher: John Wiley & Sons
ISBN: 047145592X
Category : Mathematics
Languages : en
Pages : 312

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Book Description
An effective technique for data analysis in the social sciences The recent explosion in longitudinal data in the social sciences highlights the need for this timely publication. Latent Curve Models: A Structural Equation Perspective provides an effective technique to analyze latent curve models (LCMs). This type of data features random intercepts and slopes that permit each case in a sample to have a different trajectory over time. Furthermore, researchers can include variables to predict the parameters governing these trajectories. The authors synthesize a vast amount of research and findings and, at the same time, provide original results. The book analyzes LCMs from the perspective of structural equation models (SEMs) with latent variables. While the authors discuss simple regression-based procedures that are useful in the early stages of LCMs, most of the presentation uses SEMs as a driving tool. This cutting-edge work includes some of the authors' recent work on the autoregressive latent trajectory model, suggests new models for method factors in multiple indicators, discusses repeated latent variable models, and establishes the identification of a variety of LCMs. This text has been thoroughly class-tested and makes extensive use of pedagogical tools to aid readers in mastering and applying LCMs quickly and easily to their own data sets. Key features include: Chapter introductions and summaries that provide a quick overview of highlights Empirical examples provided throughout that allow readers to test their newly found knowledge and discover practical applications Conclusions at the end of each chapter that stress the essential points that readers need to understand for advancement to more sophisticated topics Extensive footnoting that points the way to the primary literature for more information on particular topics With its emphasis on modeling and the use of numerous examples, this is an excellent book for graduate courses in latent trajectory models as well as a supplemental text for courses in structural modeling. This book is an excellent aid and reference for researchers in quantitative social and behavioral sciences who need to analyze longitudinal data.

Sign Language and Linguistic Universals

Sign Language and Linguistic Universals PDF Author: Wendy Sandler
Publisher: Cambridge University Press
ISBN: 9780521483957
Category : Language Arts & Disciplines
Languages : en
Pages : 580

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Book Description
Sign languages are of great interest to linguists, because while they are the product of the same brain, their physical transmission differs greatly from that of spoken languages. In this pioneering and original study, Wendy Sandler and Diane Lillo-Martin compare sign languages with spoken languages, in order to seek the universal properties they share. Drawing on general linguistic theory, they describe and analyze sign language structure, showing linguistic universals in the phonology, morphology, and syntax of sign language, while also revealing non-universal aspects of its structure that must be attributed to its physical transmission system. No prior background in sign language linguistics is assumed, and numerous pictures are provided to make descriptions of signs and facial expressions accessible to readers. Engaging and informative, Sign Language and Linguistic Universals will be invaluable to linguists, psychologists, and all those interested in sign languages, linguistic theory and the universal properties of human languages.

The Symbolic Species: The Co-evolution of Language and the Brain

The Symbolic Species: The Co-evolution of Language and the Brain PDF Author: Terrence W. Deacon
Publisher: W. W. Norton & Company
ISBN: 0393343022
Category : Science
Languages : en
Pages : 532

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Book Description
"A work of enormous breadth, likely to pleasantly surprise both general readers and experts."—New York Times Book Review This revolutionary book provides fresh answers to long-standing questions of human origins and consciousness. Drawing on his breakthrough research in comparative neuroscience, Terrence Deacon offers a wealth of insights into the significance of symbolic thinking: from the co-evolutionary exchange between language and brains over two million years of hominid evolution to the ethical repercussions that followed man's newfound access to other people's thoughts and emotions. Informing these insights is a new understanding of how Darwinian processes underlie the brain's development and function as well as its evolution. In contrast to much contemporary neuroscience that treats the brain as no more or less than a computer, Deacon provides a new clarity of vision into the mechanism of mind. It injects a renewed sense of adventure into the experience of being human.

Statistical Parametric Mapping: The Analysis of Functional Brain Images

Statistical Parametric Mapping: The Analysis of Functional Brain Images PDF Author: William D. Penny
Publisher: Elsevier
ISBN: 0080466508
Category : Psychology
Languages : en
Pages : 689

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Book Description
In an age where the amount of data collected from brain imaging is increasing constantly, it is of critical importance to analyse those data within an accepted framework to ensure proper integration and comparison of the information collected. This book describes the ideas and procedures that underlie the analysis of signals produced by the brain. The aim is to understand how the brain works, in terms of its functional architecture and dynamics. This book provides the background and methodology for the analysis of all types of brain imaging data, from functional magnetic resonance imaging to magnetoencephalography. Critically, Statistical Parametric Mapping provides a widely accepted conceptual framework which allows treatment of all these different modalities. This rests on an understanding of the brain's functional anatomy and the way that measured signals are caused experimentally. The book takes the reader from the basic concepts underlying the analysis of neuroimaging data to cutting edge approaches that would be difficult to find in any other source. Critically, the material is presented in an incremental way so that the reader can understand the precedents for each new development. This book will be particularly useful to neuroscientists engaged in any form of brain mapping; who have to contend with the real-world problems of data analysis and understanding the techniques they are using. It is primarily a scientific treatment and a didactic introduction to the analysis of brain imaging data. It can be used as both a textbook for students and scientists starting to use the techniques, as well as a reference for practicing neuroscientists. The book also serves as a companion to the software packages that have been developed for brain imaging data analysis. - An essential reference and companion for users of the SPM software - Provides a complete description of the concepts and procedures entailed by the analysis of brain images - Offers full didactic treatment of the basic mathematics behind the analysis of brain imaging data - Stands as a compendium of all the advances in neuroimaging data analysis over the past decade - Adopts an easy to understand and incremental approach that takes the reader from basic statistics to state of the art approaches such as Variational Bayes - Structured treatment of data analysis issues that links different modalities and models - Includes a series of appendices and tutorial-style chapters that makes even the most sophisticated approaches accessible

The Cambridge Handbook of the International Psychology of Women

The Cambridge Handbook of the International Psychology of Women PDF Author: Fanny M. Cheung
Publisher: Cambridge University Press
ISBN: 1108602185
Category : Social Science
Languages : en
Pages : 1524

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Book Description
There is a growing knowledge base in understanding the differences and similarities between women and men, as well as the diversities among women and sexualities. Although genetic and biological characteristics define human beings conventionally as women and men, their experiences are contextualized in multiple dimensions in terms of gender, sexuality, class, age, ethnicity, and other social dimensions. Beyond the biological and genetic basis of gender differences, gender intersects with culture and other social locations which affect the socialization and development of women across their life span. This handbook provides a comprehensive and up-to-date resource to understand the intersectionality of gender differences, to dispel myths, and to examine gender-relevant as well as culturally relevant implications and appropriate interventions. Featuring a truly international mix of contributors, and incorporating cross-cultural research and comparative perspectives, this handbook will inform mainstream psychology of the international literature on the psychology of women and gender.

Anomia

Anomia PDF Author: Harold Goodglass
Publisher: Academic Press
ISBN: 0080527272
Category : Medical
Languages : en
Pages : 239

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Book Description
Anomia is the inability to access spoken names for objects, most often associated with the elderly or those with brain damage to the left hemisphere. Anomia offers the state-of-the-art review of disorders of naming, written by acknowledged experts from around the world, approached from both clinical and theoretical viewpoints. Goodglass, known around the world for his research in aphasia and speech pathology, edits this first book devoted exclusively to naming and its disorders. Wingfield is known for his classic studies of lexical processing in aphasic and normal speakers. The book includes comprehensive literature reviews, a summary of relevant research data, as well as astudy of recent advances in cognitive analysis and anatomic findings. Anomia is an immensely useful work for all those involved in the study of language, particularly those in cognitive neuroscience, neurology, speech pathology, and linguistics. - Devoted entirely to naming and its disorders - Includes up-to-date descriptions of advances in cognitive analysis - Contains approaches from both clinical and theoretical viewpoints - Brings together the top researchers from the U.S., England, and Italy