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Author: Mark V. Bloom
Publisher: Benjamin-Cummings Publishing Company
ISBN:
Category : Medical
Languages : en
Pages : 468
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Book Description
This one-of-a-kind manual offers twenty-three foolproof labs designed to make molecular biology accessible and interesting to beginning biology students. Covering the basic techniques of gene manipulation and analysis, these "tried and true" experiments were tested and re-tested by the experienced author team to ensure absolute accuracy and ease of use.
Author: Mark V. Bloom
Publisher: Benjamin-Cummings Publishing Company
ISBN:
Category : Medical
Languages : en
Pages : 468
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Book Description
This one-of-a-kind manual offers twenty-three foolproof labs designed to make molecular biology accessible and interesting to beginning biology students. Covering the basic techniques of gene manipulation and analysis, these "tried and true" experiments were tested and re-tested by the experienced author team to ensure absolute accuracy and ease of use.
Author: David A. Micklos
Publisher: CSHL Press
ISBN: 9780879696368
Category : Medical
Languages : en
Pages : 858
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Book Description
This is the second edition of a highly successful textbook (over 50,000 copies sold) in which a highly illustrated, narrative text is combined with easy–to–use thoroughly reliable laboratory protocols. It contains a fully up–to–date collection of 12 rigorously tested and reliable lab experiments in molecular biology, developed at the internationally renowned Dolan DNA Learning Center of Cold Spring Harbor Laboratory, which culminate in the construction and cloning of a recombinant DNA molecule. Proven through more than 10 years of teaching at research and nonresearch colleges and universities, junior colleges, community colleges, and advanced biology programs in high school, this book has been successfully integrated into introductory biology, general biology, genetics, microbiology, cell biology, molecular genetics, and molecular biology courses. The first eight chapters have been completely revised, extensively rewritten, and updated. The new coverage extends to the completion of the draft sequence of the human genome and the enormous impact these and other sequence data are having on medicine, research, and our view of human evolution. All sections on the concepts and techniques of molecular biology have been updated to reflect the current state of laboratory research. The laboratory experiments cover basic techniques of gene isolation and analysis, honed by over 10 years of classroom use to be thoroughly reliable, even in the hands of teachers and students with no prior experience. Extensive prelab notes at the beginning of each experiment explain how to schedule and prepare, while flow charts and icons make the protocols easy to follow. As in the first edition of this book, the laboratory course is completely supported by quality–assured products from the Carolina Biological Supply Company, from bulk reagents, to useable reagent systems, to single–use kits, thus satisfying a broad range of teaching applications.
Author: Kelly M. Elkins
Publisher: Academic Press
ISBN: 0123945852
Category : Law
Languages : en
Pages : 226
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Book Description
A collection of forensic DNA typing laboratory experiments designed for academic and training courses at the collegiate level.
Author: J. Thomas McClintock
Publisher: CRC Press
ISBN: 1040084222
Category : Law
Languages : en
Pages : 165
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Book Description
In its short but active history, the use of DNA typing has revolutionized criminal investigations. It is almost inconceivable to bring a case to trial without positive identification through what is now our most accurate means. Proficiency with the methodology, principles, and interpretation of DNA evidence is crucial for today‘s criminalist.
Author: Jeffre L. Witherly
Publisher: CSHL Press
ISBN: 9780879696009
Category : Medical
Languages : en
Pages : 140
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Book Description
Defines "over 200 terms" dealing with "the language of genes, genomes, DNA, biotechnology, and heredity"--Publisher marketing.
Author: Morteza Jalali
Publisher: Academic Press
ISBN: 012803078X
Category : Science
Languages : en
Pages : 383
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Book Description
Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data. This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow's clinician scientists and future leaders in discovery science. - Serves as a helpful guide for clinical researchers who lack a conventional science background - Organized around research themes pertaining to key biological molecules, from genes, to proteins, cells, and model organisms - Features protocols, techniques for troubleshooting common problems, and an explanation of the advantages and limitations of a technique in generating conclusive data - Appendices provide resources for practical research methodology, including legal frameworks for using stem cells and animals in the laboratory, ethical considerations, and good laboratory practice (GLP)
Author: David A. Micklos
Publisher: Cold Spring Harbor Laboratory Press
ISBN:
Category : Science
Languages : en
Pages : 504
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Book Description
This laboratory text combines the theory, practice, and applications of recombinant DNA technology into one articulated package. Unlike super texts that can only be sampled by even the most ambitious instructor or student, DNA Science is designed to be read from cover to cover. The eight text chapters are written in a semi-journalistic style and adopt a historical perspective to explain where DNA science has come from and where it is going. Combining the unique perspectives of both a research biologist and a science writer, the topical treatment integrates up-to-the-minute examples drawn directly from the research literature. Extensively tested by thousands of high school and college teachers and students in 25 states and Canada, the ten laboratory experiments cover the basic techniques of gene isolation and analysis. The experiments engender systematic repetition to build student confidence and mastery of techniques. Extensive prelab notes at the beginning of each experiment explain how to schedule and prepare, and flowcharts and icons make the protocols easy to follow. The laboratory course is completely supported by quality-assured Carolina Biological Supply Company products -- from bulk reagents, to reusable reagent systems, to single-use kits -- satisfying a range of teaching applications. Truly a first course in recombinant DNA technology, the laboratory sequence presupposes no prior experience on the part of the instructor or student. Structured to follow directly from an introduction to principles of biology, the experiments are equally appropriate for the advanced high school student and the beginning college student. The book can be used as the first course in a molecularbiology sequence, be integrated as a genetics/DNA structure component of a general biology course, or be used as a unit within a microbiology or genetics course. The text is suitable for introducing recombinant DNA in science and society courses.
Author:
Publisher: Elsevier
ISBN: 0124199542
Category : Science
Languages : en
Pages : 405
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Book Description
Methods in Enzymology volumes provide an indispensable tool for the researcher. Each volume is carefully written and edited by experts to contain state-of-the-art reviews and step-by-step protocols. In this volume, we have brought together a number of core protocols concentrating on DNA, complementing the traditional content that is found in past, present and future Methods in Enzymology volumes. - Indispensable tool for the researcher - Carefully written and edited by experts to contain step-by-step protocols - In this volume we have brought together a number of core protocols concentrating on DNA
Author: Jan Anthony Witkowski
Publisher:
ISBN: 9781621821083
Category : Biography & Autobiography
Languages : en
Pages : 0
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Book Description
The Road to Discovery: A Short History of Cold Spring Harbor Laboratory was published in 2015 to mark the 125th anniversary of Cold Spring Harbor Laboratory. At Cold Spring Harbor, in a bucolic setting on the north shore of New York's Long Island, two interdependent research centers in biology were founded as Charles Darwin's insights into heredity and evolution shook the world of science. Fifty years later, those centers would emerge as a single institution that would cradle another revolution, the new science of molecular biology, and advance to world renown in research and professional education. It is a remarkable story, with a path of progress that was neither simple nor assured. The Road to Discovery traces half a century of changes in name, leadership, governance, and financial fortune. And scientific missteps, most notoriously in eugenics, were triumphed by innovative work in genetics, human metabolism, and cancer. From the 1940s through the 1960s, the Laboratory was home to fundamental discoveries about the nature of genetic material and a cauldron of critical assessment of ideas about genes by sharp-tongued summer visitors. James D. Watson, a junior member of that group, would go on to deduce the structure of DNA with Francis Crick in 1953 and help create the new field of molecular genetics before returning to Cold Spring Harbor as Director 15 years later. As the book shows, his "Bold Plan" would inspire, cajole, and goad into existence an era of expansion, new research directions, and initiatives in conferences, courses, publishing, and education that redefined the scope of the Laboratory. Under Bruce Stillman's leadership, that scope has grown still more, making the Laboratory unique among research institutions worldwide--envied, imitated, but not reproduced. The book's author is the science historian Jan Witkowski. His knowledge of the subject is wide and his affection for it deep. He brings to his task insights that only a decades-long career as a staff member can provide. For over a century, the Laboratory has been influenced by exceptional personalities, outstanding achievements, and dramatic events. The Road to Discovery captures that history in a lively narrative illuminated by vignettes on the importance of individual scientists and their discoveries. Abundantly documented with material from the Laboratory's archives, it is an accessible book that will appeal to anyone interested in the development of biomedical science and biotechnology through the 20th century to the present day.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309134404
Category : Science
Languages : en
Pages : 270
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Book Description
In 1992 the National Research Council issued DNA Technology in Forensic Science, a book that documented the state of the art in this emerging field. Recently, this volume was brought to worldwide attention in the murder trial of celebrity O. J. Simpson. The Evaluation of Forensic DNA Evidence reports on developments in population genetics and statistics since the original volume was published. The committee comments on statements in the original book that proved controversial or that have been misapplied in the courts. This volume offers recommendations for handling DNA samples, performing calculations, and other aspects of using DNA as a forensic toolâ€"modifying some recommendations presented in the 1992 volume. The update addresses two major areas: Determination of DNA profiles. The committee considers how laboratory errors (particularly false matches) can arise, how errors might be reduced, and how to take into account the fact that the error rate can never be reduced to zero. Interpretation of a finding that the DNA profile of a suspect or victim matches the evidence DNA. The committee addresses controversies in population genetics, exploring the problems that arise from the mixture of groups and subgroups in the American population and how this substructure can be accounted for in calculating frequencies. This volume examines statistical issues in interpreting frequencies as probabilities, including adjustments when a suspect is found through a database search. The committee includes a detailed discussion of what its recommendations would mean in the courtroom, with numerous case citations. By resolving several remaining issues in the evaluation of this increasingly important area of forensic evidence, this technical update will be important to forensic scientists and population geneticistsâ€"and helpful to attorneys, judges, and others who need to understand DNA and the law. Anyone working in laboratories and in the courts or anyone studying this issue should own this book.
