Investigation of the Pharmacokinetics of Diazepam in Juvenile Channel Catfish (Ictalurus Punctatus)

Investigation of the Pharmacokinetics of Diazepam in Juvenile Channel Catfish (Ictalurus Punctatus) PDF Author: Carmen L. Overturf
Publisher:
ISBN:
Category : Channel catfish
Languages : en
Pages : 99

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The Pharmacokinetics of Sulfachlorpyridazine in Channel Catfish (Ictalurus Punctatus)

The Pharmacokinetics of Sulfachlorpyridazine in Channel Catfish (Ictalurus Punctatus) PDF Author: Fereidon Khan Alavi
Publisher:
ISBN:
Category :
Languages : en
Pages : 132

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The Pharmacokinetics of Gentamicin in Channel Catfish (Ictalurus Punctatus)

The Pharmacokinetics of Gentamicin in Channel Catfish (Ictalurus Punctatus) PDF Author: Mark Duane Setser
Publisher:
ISBN:
Category :
Languages : en
Pages : 188

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Temperature and Species Comparisons of Benzocaine Pharmacokinetics, Metabolism and Physiologically Based Pharmacokinetic Model Within Channel Catfish, Ictalurus Punctatus, and Yellow Perch, Perca Flavescens

Temperature and Species Comparisons of Benzocaine Pharmacokinetics, Metabolism and Physiologically Based Pharmacokinetic Model Within Channel Catfish, Ictalurus Punctatus, and Yellow Perch, Perca Flavescens PDF Author: Kelli J. Clark
Publisher:
ISBN:
Category :
Languages : en
Pages : 520

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Abstract: Benzocaine, a local anesthetic for mammals, has potential for use as a general anesthetic in finfish. Its pharmacokinetics, metabolism, and residue profiles were characterized to support its approval in fish. To compare interspecies and temperature differences of these parameters channel catfish were studied at 16, 21, and 260C and yellow perch at 160C. The feasibility of "crop grouping" was investigated with a physiologically based pharmacokinetic (PBPK) model as a means to reduce the amount of testing required for aquaculture drug registration.

Pharmacokinetics and Metabolism of Sulfadimethoxine in Channel Catfish (Ictalurus Punctatus)

Pharmacokinetics and Metabolism of Sulfadimethoxine in Channel Catfish (Ictalurus Punctatus) PDF Author: Catherine M. F. Michel
Publisher:
ISBN:
Category :
Languages : en
Pages : 400

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Anaesthetic and Sedative Techniques for Aquatic Animals

Anaesthetic and Sedative Techniques for Aquatic Animals PDF Author: Lindsay G. Ross
Publisher: John Wiley & Sons
ISBN: 1444302272
Category : Technology & Engineering
Languages : en
Pages : 240

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Book Description
The second edition of Anaesthetic and Sedative Techniques forAquatic Animals provided the fisheries and aquaculture industrywith vital information on the use of sedation and anaesthetics inthe avoidance of stress and physical damage, which can easily becaused by crowding, capture, handling, transportation and release. Now fully revised and expanded, the third edition has maintainedits accessible format and incorporates much new emphasis on: • Fish pain and welfare: a rapidly developing area ofinterest and debate • Anaesthesia and legislation: with an internationalperspective Personnel involved in the aquaculture industry including fishfarmers, fish veterinarians, fisheries scientists and fishbiologists along with small animal veterinarians, animal laboratorymanagers and government and regulatory personnel will find thisbook a valuable and practical resource.

Arterial Chemoreception

Arterial Chemoreception PDF Author: Colin A. Nurse
Publisher: Springer Science & Business Media
ISBN: 9400745834
Category : Medical
Languages : en
Pages : 399

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Book Description
Arterial chemoreceptors are unique structures which continuously monitor changes in arterial blood oxygen, carbon dioxide, glucose, and acid. Alterations in these gases are almost instantaneously sensed by arterial chemoreceptors and relayed into a physiological response which restores blood homeostasis. Arterial Chemoreception contains updated material regarding the physiology of the primary arterial chemoreceptor; the carotid body. Moreover, this book also explores tantalizing evidence regarding the contribution of the aortic bodies, chromaffin cells, lung neuroepithelial bodies, and brainstem areas involved in monitoring changes in blood gases. Furthermore this collection includes data showing the critical importance of these chemoreceptors in the pathophysiology of human disease and possible therapeutic treatments. This book is a required text for any researcher in the field of arterial chemoreception for years to come. It is also a critical text for physicians searching for bench-to-bedside treatments for heart failure, sleep apnea, and pulmonary hypertension.

Target Organ Toxicity in Marine and Freshwater Teleosts

Target Organ Toxicity in Marine and Freshwater Teleosts PDF Author: Daniel Schlenk
Publisher: CRC Press
ISBN: 0203361407
Category : Medical
Languages : en
Pages : 426

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Book Description
Addressing the numerous gaps in current information, Target Organ Toxicology in Marine and Freshwater Teleosts is an essential resource for researchers and professionals in aquatic toxicology and environmental risk assessment. All the chapters are written by researchers who are internationally recognised for their work in mechanistic aspects of aquatic toxicology. Each chapter focuses on a specific target organ or physiological system and describes how various agents disrupt the normal physiological system and processes. This volume is devoted to specific organs with coverage of the gill, kidney, skin, liver and gut. The companion volume, Systems, provides coverage of toxic effects in the central nervous, immune, neurobehavioural and reproductive systems as well as describing general mechanisms of toxicity.

Venomous Reptiles and Their Toxins

Venomous Reptiles and Their Toxins PDF Author: Bryan Fry
Publisher: Oxford University Press
ISBN: 0190297581
Category : Science
Languages : en
Pages : 576

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Book Description
Venom research and technology has advanced greatly, rapidly transforming our knowledge of reptile venoms. Research advances, like the development of molecular systematics, provide the framework necessary to reconstruct the evolutionary history of glands and fangs. Such research developments have expanded our understanding of venom's evolution and its usefulness in therapeutic development. The results of this punctuated toxin molecular evolutionary expansion include protein neofunctionalization. While these changes may impact antivenom efficacy, this molecular diversity also facilitates their usefulness in the development of novel drug therapies. Venomous Reptiles And Their Toxins brings together the world's leading toxinologists in this comprehensive study of the entire scope of reptile venoms, from clinical effects to evolution to drug design and development. The book contains detailed applied chapters on clinical care of the envenomed patient, ineffective traditional or modern remedies, occupational considerations involved in the maintenance of institutional venomous reptile collections, veterinary care for venomous reptiles and research methods used in venom research. This book also devotes a chapter to each toxin class found in reptile venoms, detailing the full trajectory of research on the peptide or protein in question. These chapters discuss each toxin's respective role in the envenomation process through to how each has been explored for their biomedical potential. This book is a unique resource for anyone working with venomous reptiles.

Environmental Contaminants in Biota

Environmental Contaminants in Biota PDF Author: W. Nelson Beyer
Publisher: CRC Press
ISBN: 1420084062
Category : Science
Languages : en
Pages : 750

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Book Description
Examining tissue residues of contaminants in biota reveals the movement of contaminants within organisms and through food chains as well as the context for understanding and quantifying injuries to organisms and their communities. Yet tissue concentrations of some contaminants are especially challenging to interpret and the ability of today’s analytical chemists to provide reliable analytical data of most important environmental contaminants often surpasses the ability of ecotoxicologists to interpret those data. Offering guidance on the ecotoxicologically meaningful interpretation of tissue concentrations, Environmental Contaminants in Biota, Interpreting Tissue Concentrations, Second Edition is updated with current data and new ways of analyzing those data as well as additional contaminants not previously considered. Beginning with a history of wildlife toxicology and data interpretation, chapters cover a wide range of contaminants and their hazardous and lethal concentrations in various animals including DDT, Dioxins, PCBs, and PBDEs in aquatic organisms; methylmurcury, selenium, and trace metals in fishes and aquatic invertebrates; and pharmaceuticals and organic contaminants in marine mammals. The book considers the impact of Polychlorinated Biphenyls, Dibenzo-p-Dioxins and Dibenzofurans, and Polybrominated Diphenyl Ethers; cyclodiene; and other organochlorine pesticides in birds and mammals. Later chapters examine the effects and analysis of lead, cadmium, and radionuclides in biota. With thousands of published research papers reporting tissue concentrations each year, Environmental Contaminants in Biota, Interpreting Tissue Concentrations, Second Edition gives ecotoxicologists the ability to draw actionable value regarding the toxicological consequences of those concentrations and relate tissue concentrations quantitatively to injury: the core of ecotoxicology.