Microsomes and Drug Oxidations

Microsomes and Drug Oxidations PDF Author: Volker Ullrich
Publisher: Elsevier
ISBN: 1483159086
Category : Medical
Languages : en
Pages : 805

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Book Description
Microsomes and Drug Oxidations is a record of the proceedings of the Third International Symposium on Microsomes and Drug Oxidations, held in Berlin, Germany in July 1976. The compendium provides an overview of knowledge on the oxidative metabolism of drugs, carcinogens, and various other environmental chemicals. Topics discussed include lipid structure of liver microsomal membranes; interactions between cytochrome p-450 and nadphcytochrome p-450 reductase in the microsomal membrane; impact of drug monoxygenases in clinical pharmacology; and the manner in which oxygen participates in mixed-function oxidation reactions. Pharmacologists, toxicologists, biochemists, and researchers in the pharmaceutical industry will find the book highly insightful.

Microsomes and Drug Oxidations

Microsomes and Drug Oxidations PDF Author: Volker Ullrich
Publisher: Elsevier
ISBN: 1483159086
Category : Medical
Languages : en
Pages : 805

Get Book Here

Book Description
Microsomes and Drug Oxidations is a record of the proceedings of the Third International Symposium on Microsomes and Drug Oxidations, held in Berlin, Germany in July 1976. The compendium provides an overview of knowledge on the oxidative metabolism of drugs, carcinogens, and various other environmental chemicals. Topics discussed include lipid structure of liver microsomal membranes; interactions between cytochrome p-450 and nadphcytochrome p-450 reductase in the microsomal membrane; impact of drug monoxygenases in clinical pharmacology; and the manner in which oxygen participates in mixed-function oxidation reactions. Pharmacologists, toxicologists, biochemists, and researchers in the pharmaceutical industry will find the book highly insightful.

Current Catalog

Current Catalog PDF Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1144

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Book Description
First multi-year cumulation covers six years: 1965-70.

National Library of Medicine Current Catalog

National Library of Medicine Current Catalog PDF Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1256

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Book Description
First multi-year cumulation covers six years: 1965-70.

Microsomes, Drug Oxidations and Chemical Carcinogenesis V2

Microsomes, Drug Oxidations and Chemical Carcinogenesis V2 PDF Author: Minor Coon
Publisher: Elsevier
ISBN: 0323143873
Category : Medical
Languages : en
Pages : 655

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Book Description
Microsomes, Drug Oxidations, and Chemical Carcinogenesis, Volume II, documents the proceedings of the 4th International Symposium on Microsomes and Drug Oxidations held in Ann Arbor, July 1979. The symposium reviewed progress in the understanding of scientific and biomedical problems from a biochemical, biophysical, pharmacological, and toxicological perspective. Volume I contained 117 contributions made by researchers at the symposium, which were organized into three sections (Sections I-III). This second volume contains 122 contributions, divided into four sections (Sections IV-VII). The papers on Section IV examine the metabolic fate of oxygenated compounds. Section V provides studies on microsomal enzymes and lipid metabolism. Section VI includes papers on microsomal enzymes and toxicity of foreign compounds. Section VII covers microsomal enzymes and chemical mutagenesis and carcinogenesis. This book seeks to aid future progress in understanding the complexities of metabolic transformations by these versatile enzyme systems that act on physiologically important lipids as well as on a wide array of foreign substances, including drugs, anesthetics, industrial chemicals, food additives, pesticides, carcinogens, and nonnutrient dietary chemicals.

Environmental Health Perspectives

Environmental Health Perspectives PDF Author:
Publisher:
ISBN:
Category : Environmental health
Languages : en
Pages : 584

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Book Description


Toxicological Evaluation of Chemical Interactions

Toxicological Evaluation of Chemical Interactions PDF Author:
Publisher:
ISBN:
Category : Toxicological interactions
Languages : en
Pages : 704

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Book Description


American Book Publishing Record

American Book Publishing Record PDF Author:
Publisher: R. R. Bowker
ISBN:
Category : Reference
Languages : en
Pages : 1438

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Book Description


Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells

Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells PDF Author: T.E. Gram
Publisher: Elsevier
ISBN: 1483287629
Category : Medical
Languages : en
Pages : 325

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Book Description
Research has shown that the lung is capable of metabolically activating xenobiotics into intermediates that can covalently bind to pulmonary tissue. Further, it has been shown that the lung consists of many distinct cell types with the ability to take up and sequester metabolically unchanged drugs and chemicals that are ultimately toxic in effect. This volume reflects the extent of these developments and provides a state-of-the art reference in a rapidly evolving field incorporating both drug metabolism and pulmonary toxicology research.

国立国会図書館所蔵科学技術関係欧文会議錄目錄

国立国会図書館所蔵科学技術関係欧文会議錄目錄 PDF Author: 国立国会図書館 (Japan)
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 672

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Book Description


Guide to Cytochromes

Guide to Cytochromes PDF Author: David F.V. Lewis
Publisher: CRC Press
ISBN: 0748404430
Category : Science
Languages : en
Pages : 344

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Book Description
This guide to the structure, function and mechanism of the cytochromes P450 focuses on the role of P450s in xenobiotic metabolism and toxicity. Colour illustrations show how modelling of P450s can rationalize their substrate specificity for the metabolism of both endogenous and exogenous chemicals.