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Author: Yu Sun
Publisher: Cambridge University Press
ISBN: 1316462544
Category : Technology & Engineering
Languages : en
Pages : 385
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Book Description
The first of its kind, this comprehensive resource integrates cellular mechanobiology with micro-nano techniques to provide unrivalled in-depth coverage of the field, including state-of-the-art methods, recent advances, and biological discoveries. Structured in two parts, the first part offers detailed analysis of innovative micro-nano techniques including FRET imaging, electron cryo-microscopy, micropost arrays, nanotopography devices, laser ablation, and computational image analysis. The second part of the book provides valuable insights into the most recent technological advances and discoveries in areas such as stem cell, heart, bone, brain, tumor, and fibroblast mechanobiology. Written by a team of leading experts and well-recognised researchers, this is an essential resource for students and researchers in biomedical engineering.
Author: Yu Sun
Publisher: Cambridge University Press
ISBN: 1316462544
Category : Technology & Engineering
Languages : en
Pages : 385
Get Book Here
Book Description
The first of its kind, this comprehensive resource integrates cellular mechanobiology with micro-nano techniques to provide unrivalled in-depth coverage of the field, including state-of-the-art methods, recent advances, and biological discoveries. Structured in two parts, the first part offers detailed analysis of innovative micro-nano techniques including FRET imaging, electron cryo-microscopy, micropost arrays, nanotopography devices, laser ablation, and computational image analysis. The second part of the book provides valuable insights into the most recent technological advances and discoveries in areas such as stem cell, heart, bone, brain, tumor, and fibroblast mechanobiology. Written by a team of leading experts and well-recognised researchers, this is an essential resource for students and researchers in biomedical engineering.
Author: Clark Spencer Larsen
Publisher: John Wiley & Sons
ISBN: 111982804X
Category : Social Science
Languages : en
Pages : 677
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Book Description
A Companion to Biological Anthropology The discipline of biological anthropology—the study of the variation and evolution of human beings and their evolutionary relationships with past and living hominin and primate relatives—has undergone enormous growth in recent years. Advances in DNA research, behavioral anthropology, nutrition science, and other fields are transforming our understanding of what makes us human. A Companion to Biological Anthropology provides a timely and comprehensive account of the foundational concepts, historical development, current trends, and future directions of the discipline. Authoritative yet accessible, this field-defining reference work brings together 37 chapters by established and younger scholars on the biological and evolutionary components of the study of human development. The authors discuss all facets of contemporary biological anthropology including systematics and taxonomy, population and molecular genetics, human biology and functional adaptation, early primate evolution, paleoanthropology, paleopathology, bioarchaeology, forensic anthropology, and paleogenetics. Updated and expanded throughout, this second edition explores new topics, revisits key issues, and examines recent innovations and discoveries in biological anthropology such as race and human variation, epidemiology and catastrophic disease outbreaks, global inequalities, migration and health, resource access and population growth, recent primate behavior research, the fossil record of primates and humans, and much more. A Companion to Biological Anthropology, Second Edition is an indispensable guide for researchers and advanced students in biological anthropology, geosciences, ancient and modern disease, bone biology, biogeochemistry, behavioral ecology, forensic anthropology, systematics and taxonomy, nutritional anthropology, and related disciplines.
Author: Sam D. Stout
Publisher: CRC Press
ISBN: 1040151205
Category : Social Science
Languages : en
Pages : 751
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Book Description
Bone Histology: A Biological Anthropological Perspective, Second Edition builds on the success of the first edition, recognizing the significant advances that have occurred in bone biology, histology, and histological techniques and methods in subsequent years. Bones and teeth are of considerable importance for anthropological and related research, due to their nature as hard tissues. The physical remains of humans available to biological anthropologists, bioarchaeologists, paleopathologists, and paleontologists are, with exception to forensic anthropology, limited to skeletal material; fortunately, the same characteristics of hard tissues that lead to their persistence after death make them a storehouse of information about biological processes experienced during the life of the individual. This book covers important aspects of bone biology which underlie the microstructure of hard tissues that are crucial for histological analysis. This includes an overview of two major metabolic processes, bone remodelling and modelling, and their importance for understanding and interpreting bone histomorphology. Subsequent chapters apply histological methods to the biological profile, such as estimation of age and evaluation of pathological conditions that affect the skeleton, or to determine whether remains are human or nonhuman. Finally, there is a discussion of current research trends in bone histology, with a focus on technological advances in imaging and methods. Reviews of four well-documented skeletal collections—developed specifically for bone histological and imaging research—are discussed, as well as, the importance of such collections for future research. Bone Histology, Second Edition has assembled a collection of contributing authors, with extensive experience and expertise in various aspects of hard tissue biology, to provide readers with an overview of the current state of research and potential applications of histological analysis in biological anthropology, forensic anthropology, and skeletal biology. It serves as a valuable resource for students, researchers, and practitioners in these and related disciplines.
Author: Przemyslaw Wojtaszek
Publisher: Springer Science & Business Media
ISBN: 364219091X
Category : Science
Languages : en
Pages : 356
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Book Description
Chemical reactions and interactions between molecules are commonly considered the basis of life, and thus the biochemical nature of cells and organisms is relatively well recognized. Research conducted in recent years, however, increasingly indicates that physical forces profoundly affect the functioning of life at all levels of its organization. To detect and to respond to such forces, plant cells and plants need to be structured mechanically. This volume focuses on mechanical aspects of plant life. It starts with a consideration of the mechanical integration of supracellular structures and mechanical properties of cellular building blocks to show how the structural integrity of plant cells is achieved and maintained during growth and development. The following chapters reveal how the functioning of integrated plant cells contributes to the mechanical integration of plants, and how the latter are able to detect physical stimuli and to reorganize their own cells in response to them. The mechanical aspects of plant responses to stresses are also presented. Finally, all these aspects are placed in an evolutionary context.
Author: Xinyu Liu
Publisher: Academic Press
ISBN: 0128242434
Category : Science
Languages : en
Pages : 406
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Book Description
Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms provides a comprehensive introduction to the state-of-the-art micro and nano systems that have recently been developed and applied to biophysical studies of cells and small organisms. These micro and nano systems span from microelectromechanical systems (MEMS) and microfluidic devices to robotic micro-nanomanipulation systems. These biophysical studies range from cell mechanics to the neural science of worms and Drosophila. This book will help readers understand the fundamentals surrounding the development of these tools and teach them the most recent advances in cellular and organismal biophysics enabled by these technologies. - Comprehensive coverage of micro and nano-system technology and application to biophysical studies of cells and small organisms. - Highlights the most recent advances in cellular and organismal biophysics enabled by micro and nano systems. - Insightful outlook on future directions and trends in each chapter covering a sub-area of the book topic.
Author: J. F. Stoltz
Publisher: IOS Press
ISBN: 9781586039271
Category : Medical
Languages : en
Pages : 372
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Book Description
This book covers the proceedings of the Fifth Symposium on Mechanobiology of Cartilage and Chondrocyte. Mechanobiology can be now considered as a vigorous branch of biomechanics, biorheology and physiology mainly concerned with the study of the influence of mechanical forces on cells and tissues and their clinical or therapeutical applications. As we are now in the age of proteomics, genomics and cell micro mechanical approaches, suing methods like laser tweezers or confocal microscopy, mechanobiology brings new challenges. With such new research, mechanobiology promises new diagnostic and therapeutic approaches. In other respect there has been increasing interest over recent years in the fundamental role played by local mechanical parameters in chondrocyte regulations and cartilage dysfunctions as a first step in the development of osteoarthritis. These proceedings are sub-divided into four parts: Theoretical approaches and mechanobiology of chondrocyte; Cartilage and chondrocyte studies; Osteoarthritis: inflammation degradation and clinical approaches; and, Cartilage engineering
Author: Catherine Coutand
Publisher: Frontiers Media SA
ISBN: 2889450740
Category :
Languages : en
Pages : 95
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Book Description
During the 1970s, renewed interest in plant mechanical signaling led to the discovery that plants subjected to mechanical stimulation develop shorter and thicker axes than undisturbed plants, a syndrome called thigmomorphogenesis. Currently, mechanosensing is being intensively studied because of its involvement in many physiological processes in plants and particularly in the control of plant morphogenesis. From an ecological point of view, the shaping of plant architecture has to be precisely organized in space to ensure light capture as well as mechanical stability. In natural environments terrestrial plants are subjected to mechanical stimulation mainly due to wind, but also due to precipitation, while aquatic and marine plants are subjected to current and wave energy. Plants acclimate to mechanically challenging environments by sensing mechanical stimulations and modifying their growth in length and diameter and their tissue properties to reduce potential for buckling or breakage. From a morphogenetic point of view, both external and internal mechanical cues play an important role in the control of cell division and meristem development likely by modulating microtubule orientation. How mechanical stimulations are being sensed by plants is an area of intense research. Different types of mechanosensors have been discovered or proposed, including ion channels gated by membrane tension (stretch activation) and plasma membrane receptor-like kinases that monitor the cell wall deformations. Electrophysiologists have measured the conductances of some stretch-activated channels and have showed that SAC of different structures can exhibit different conductances. The role of these differences in conductance has not yet been established. Once a mechanical stimulus has been perceived, it must be converted into a biological signal that can lead to variations of plant phenotype. Calcium has been shown to function as an early second messenger, tightly linked with changes in cytosolic and apoplastic pH. Transcriptional analyses of the effect of mechanical stimulation have revealed a considerable number of differentially expressed genes, some of which appear to be specific to mechanical signal transduction. These genes can thus serve as markers of mechanosensing, for example, in studies attempting to define signalling threshold, or variations of mechanosensitivity (accommodation). Quantitative biomechanical studies have lead to a model of mechanoperception which links mechanical state and plant responses, and provides an integrative tool to study the regulation of mechanosensing. This model includes parameters (sensitivity and threshold) that can be estimated experimentally. It has also been shown that plants are desensitized when exposed to multiple mechanical signals as a function of their mechanical history. Finally, mechanosensing is also involved in osmoregulation or cell expansion. The links between these different processes involving mechanical signalling need further investigation. This frontier research topic provides an overview of the different aspects of mechanical signaling in plants, spanning perception, effects on plant growth and morphogenesis, and broad ecological significance.
Author:
Publisher: ScholarlyEditions
ISBN: 1464963339
Category : Science
Languages : en
Pages : 5108
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Book Description
Issues in Biological and Life Sciences Research: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biological and Life Sciences Research. The editors have built Issues in Biological and Life Sciences Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biological and Life Sciences Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biological and Life Sciences Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author: Charles M. Cuerrier
Publisher: CRC Press
ISBN: 9814613371
Category : Medical
Languages : en
Pages : 399
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Book Description
With the recent development of new experimental approaches and methodologies, it is becoming clear that cells and tissues are not regulated by biochemical signals alone. Indeed, physical cues arising in the biological microenvironment are directly coupled to the biochemical regulation of living systems. This book provides a broad overview of how me
Author: Shu Chien
Publisher: Springer
ISBN: 9781493956159
Category : Medical
Languages : en
Pages : 0
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Book Description
This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across different scales from molecular sensing to mechanotransduction and gene modulation for physiological regulation of cellular functions will be explored, as well as applications to pathophysiological states in disease. A comprehensive understanding of the roles of physicochemical microenvironment and intracellular responses in determining cellular function in health and disease will also be discussed.
