Integrative Approaches to Molecular Biology PDF Download
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Author: Julio Collado-Vides
Publisher: MIT Press
ISBN: 9780262032391
Category : Bioinformatics
Languages : en
Pages : 372
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Book Description
It charts the course of the emerging discipline of integrative molecular biology from macromolecular sequences to a biological (and theoretical) perspective, showing that novel integrative methodologies and paradigms are emerging at the confluence of such disciplines as computer science, logic, linguistics, and mathematics.
Author: Julio Collado-Vides
Publisher: MIT Press
ISBN: 9780262032391
Category : Bioinformatics
Languages : en
Pages : 372
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Book Description
It charts the course of the emerging discipline of integrative molecular biology from macromolecular sequences to a biological (and theoretical) perspective, showing that novel integrative methodologies and paradigms are emerging at the confluence of such disciplines as computer science, logic, linguistics, and mathematics.
Author: Julio Collado-Vides (ed)
Publisher:
ISBN: 9788180520549
Category :
Languages : en
Pages : 345
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Book Description
Author: J. Colicelli
Publisher:
ISBN: 9781118305577
Category : Science
Languages : en
Pages : 832
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Book Description
Author: Manish Kumar Gupta
Publisher: Elsevier
ISBN: 0443160937
Category : Science
Languages : en
Pages : 434
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Book Description
Integrative Omics: Concepts, Methodology and Applications provides a holistic and integrated view of defining and applying network approaches, integrative tools, and methods to solve problems for the rationalization of genotype to phenotype relationships. The reference includes a range of chapters in a systemic ‘step by step’ manner, which begins with the basic concepts from Omic to Multi Integrative Omics approaches, followed by their full range of approaches, applications, emerging trends, and future trends. All key areas of Omics are covered including biological databases, sequence alignment, pharmacogenomics, nutrigenomics and microbial omics, integrated omics for Food Science and Identification of genes associated with disease, clinical data integration and data warehousing, translational omics as well as omics technology policy and society research. Integrative Omics: Concepts, Methodology and Applications highlights the recent concepts, methodologies, advancements in technologies and is also well-suited for researchers from both academic and industry background, undergraduate and graduate students who are mainly working in the area of computational systems biology, integrative omics and translational science. The book bridges the gap between biological sciences, physical sciences, computer science, statistics, data science, information technology and mathematics by presenting content specifically dedicated to mathematical models of biological systems. Provides a holistic, integrated view of a defining and applying network approach, integrative tools, and methods to solve problems for rationalization of genotype to phenotype relationships Offers an interdisciplinary approach to Databases, data analytics techniques, biological tools, network construction, analysis, modeling, prediction and simulation of biological systems leading to ‘translational research’, i.e., drug discovery, drug target prediction, and precision medicine Covers worldwide methods, concepts, databases, and tools used in the construction of integrated pathways
Author: Julio Collado-Vides
Publisher: MIT Press
ISBN: 9780262532686
Category : Computers
Languages : en
Pages : 326
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Book Description
An overview of current computational approaches to metabolism and gene regulation.
Author: Enrique Hernández-Lemus
Publisher: Frontiers Media SA
ISBN: 2889458008
Category :
Languages : en
Pages : 334
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Book Description
"Integrative Approaches to the Molecular Physiology of Inflammation" presents contributions from the many different fields and approaches to the physiology and the molecular origins of inflammation; particularly those that may be involved in the development and evolution of diseased phenotypes. We selected among the wide scope and multiple views used to probe into the molecular origins of complex inflammatory phenotypes. This book consists of an Introductory Editorial and 6 thematic chapters encompassing 24 articles: 17 original research contributions and 7 review articles (5 reviews, 1 systematic review, and 1 minireview). Both, the research papers and the reviews provide varied and insightful approaches to different facets of inflammation with approaches ranging from general inflammation and signaling depictions deeply rooted on functional biology and physiology, to computational systems biology analyses, translational medicine, and pharmacological explorations. Model systems are also quite diverse: human subjects, mice and other mammal models, cell cultures and in silico, complex networks and database studies.
Author: Haruki Nakamura
Publisher: Springer
ISBN: 9811322007
Category : Science
Languages : en
Pages : 272
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Book Description
This book presents a new emerging concept of "Integrative Structural Biology". It covers current trends of the molecular and cellular structural biology, providing new methods to observe, validate, and keep the structural models of the large cellular machines with recent scientific results. Structures of very large macromolecular machines in cells are being determined by combining observations from complementary experimental methods. Thus, this volume presents the each methods such as X-ray crystallography, NMR spectroscopy, 3DEM, small-angle scattering (SAS), FRET, crosslinking, and enables the readers to understand the hybrid methods. This book discusses how those integrative models should be represented, validated and archived. A unique highlight of this book is discussion of the data validation and archive, which are big problems in this filed along with the progress of this field. The researchers in biology will be interested in this book as a guide book for learning the current structure biology, but also those in structure biology may use this book as a comprehensive reference to cover broad topics.
Author: Colicelli
Publisher:
ISBN: 9781118294444
Category :
Languages : en
Pages : 832
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Book Description
Author: John T. Tansey
Publisher: John Wiley & Sons
ISBN: 1119610559
Category : Science
Languages : en
Pages : 994
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Book Description
Biochemistry: An Integrative Approach with Expanded Topics is addressed to premed, biochemistry, and life science majors taking a two-semester biochemistry course. This version includes all 25 chapters, offering a holistic approach to learning biochemistry. An integrated, skill-focused approach to the study of biochemistry and metabolism Biochemistry integrates subjects of interest to undergraduates majoring in premed, biochemistry, life science, and beyond, while preserving a chemical perspective. Respected biochemistry educator John Tansey takes a unique approach to the subject matter, emphasizing problem solving and critical thinking over rote memorization. Key concepts such as metabolism, are introduced and then revisited and cross-referenced throughout the text to establish pattern recognition and help students commit their new knowledge to long-term memory. As part of WileyPLUS, Biochemistry includes access to video walkthroughs of worked problems, interactive elements, and expanded end-of-chapter problems with a wide range of subject matter and difficulty. Students will have access to both qualitative and quantitative worked problems, and videos model the biochemical reasoning students will need to master. This approach helps students learn to analyze data and make critical assessments of experiments—key skills for success across scientific disciplines. Introduces students in scientific majors to the basics of biochemistry and metabolism Integrates and synthesizes topics throughout the text, allowing students to learn through repetition and pattern recognition Emphasizes problem solving and reasoning skills essential to life sciences, including data analysis and research assessment Provides access to video walkthroughs of worked problems, interactive features, and additional study material through WileyPLUS This volume covers DNA, RNA, gene regulation, synthetic proteins, omics, plant biochemistry, and more. With this text, students studying a range of disciplines are empowered to develop a lasting foundation in biochemistry and metabolism that will serve them as they advance through their careers.
Author: Andrea T. da Poian
Publisher: Springer
ISBN: 1493930583
Category : Medical
Languages : en
Pages : 433
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Book Description
This book covers in detail the mechanisms for how energy is managed in the human body. The basic principles that elucidate the reactivity and physical interactions of matter are addressed and quantified with simple approaches. Three-dimensional representations of molecules are presented throughout the book so molecules can be viewed as unique entities in their shape and function. The book is focused on the molecular mechanisms of cellular processes in the context of human physiological situations such as fasting, feeding and physical exercise, in which metabolic regulation is highlighted. Furthermore the book uses key historical experiments that opened up new concepts in Biochemistry to further illustrate how the human body functions at molecular level, helping students to appreciate how scientific knowledge emerges. This book also: Elucidates the foundations of the molecular events of life Uses key historical experiments that opened up new concepts in Biochemistry to further illustrate how the human body functions at molecular level, helping students to appreciate how scientific knowledge emerges Provides realistic representations of molecules throughout the book Advance Praise for Integrative Human Biochemistry “This textbook provides a modern and integrative perspective of human biochemistry and will be a faithful companion to health science students following curricula in which this discipline is addressed. This textbook will be a most useful tool for the teaching community.” –Joan Guinovart Director of the Institute for Research in Biomedicine, Barcelona, Spain President-elect of the International Union of Biochemistry and Molecular Biology, IUBMB
