Integrated Study of Gastritis PDF Download
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Author: Mikhael Kular
Publisher:
ISBN: 9781632412669
Category :
Languages : en
Pages : 0
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Book Description
This book provides an integrated analysis of gastritis. The term Gastritis was first coined around 150 years ago, yet its etiology and prognosis has changed as medical complications related to gastritis are in the focus of distinct sub-disciplines like ga
Author: Mikhael Kular
Publisher:
ISBN: 9781632412669
Category :
Languages : en
Pages : 0
Get Book Here
Book Description
This book provides an integrated analysis of gastritis. The term Gastritis was first coined around 150 years ago, yet its etiology and prognosis has changed as medical complications related to gastritis are in the focus of distinct sub-disciplines like ga
Author: Rodolfo Cheli
Publisher: Springer
ISBN: 9783642718465
Category : Medical
Languages : en
Pages : 242
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Book Description
This comprehensive and important book examines gastritis in all its aspects with scholarship that arises from the authors' intimate knowledge of the subject. Professor CHELl has contributed to the study of gastritis for over 30 years, and every section of this book lists references to his important publications. I share the view of the authors that endoscopic or macroscopic appearances are only an introduction to the proper study of gastritis. They correctly stress the histologic basis for diagnosing, classifying and understanding gastritis, leading us from an histori cal review through normal morphology, and from acute gastritis to chronic gastritis which is examined critically in great detail with respect to clinical manifestations ans pathophysiologic changes, and is then related to other disorders such as peptic ulcer, polyps and endocrine tumors. The description continues with specific forms of gastritis including that most difficult condi tion, gastritis of the surgically operated stomach. The coverage in all areas is comprehensive and fully documented from the litera ture, which has been critically interpreted. The organization and completeness of this work will long serve as guide and reference to those who seek to know gastritis.
Author: Shruti Marwaha
Publisher:
ISBN:
Category :
Languages : en
Pages : 134
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Book Description
Gastric cancer is the fifth most common malignancy in the world and third the leading cause of cancer-related mortality worldwide, with five-year survival rate of only 20-29%. In order to develop better drugs, diagnostics and preventive measures for gastric cancer, it is critical to understand the underlying molecular biology of the disease and factors that increase the risk for the disease. Helicobacter pylori-induced chronic gastritis is a major risk factor associated with gastric cancer development. We analyzed publically available gene expression data from patients with gastric cancer and patients with H. pylori mediated gastritis, to identify genes and pathways that play an important role in the two diseases. We further integrated the identified disease signature with Broad Institute's Connectivity Map to identify and prioritize drugs that can potentially reverse the molecular signature of gastric cancer cells and that of gastric tumors resistant to Cisplatin-Flurouracil (CF) chemotherapy. Our analysis identified vorinostat, trichostatin A and thiostrepton as potential therapeutic compounds for gastric cancer treatment. We identified genes and pathways that are differentially expressed (57 up-regulated and 86 down-regulated) in both gastric cancer and H. pylori mediated atrophic gastritis. The topmost pathways enriched for these genes include - cell-cell adhesion/communication, tight junctions, leukocyte transendothelial migration, gastric acid secretion, potassium ion transport and creatine pathways. Analysis of CF resistant and sensitive tumors suggests the role of metabolic and statin pathways towards resistance to the chemotherapy. We also developed a mathematical model of a sub-network comprising of sonic hedgehog (SHH), pro-inflammatory cytokines and anti-inflammatory cytokines, which play a critical role in H. pylori mediated gastritis. We integrated qPCR results, mathematical modeling technique and microarray data from H. pylori infected mice to explore the temporal behavior of the cytokine-SHH sub-network. Our mathematical model suggests that NF?B, SHH and the cytokines engage in a feedback loop which can result in damped oscillations. The model helps to bring out emergent properties of the network and generate testable hypotheses. Future experiments capturing cytokines and SHH profile over time can reveal more insights about the relationship between the different genes, their regulation and improve our current understanding of the dynamics and sequence of the events in the system.
Author: Paola Tonino
Publisher: BoD – Books on Demand
ISBN: 9533073756
Category : Medical
Languages : en
Pages : 312
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Book Description
This book is a comprehensive overview of invited contributions on Helicobacter pylori infection in gastritis and gastric carcinogenesis. The first part of the book covers topics related to the pathophysiology of gastric mucosal defense system and gastritis including the gastroprotective function of the mucus, the capsaicin-sensitive afferent nerves and the oxidative stress pathway involved in inflammation, apoptosis and autophagy in H. pylori related gastritis. The next chapters deal with molecular pathogenesis and treatment, which consider the role of neuroendocrine cells in gastric disease, DNA methylation in H. pylori infection, the role of antioxidants and phytotherapy in gastric disease. The final part presents the effects of cancer risk factors associated with H. pylori infection. These chapters discuss the serum pepsinogen test, K-ras mutations, cell kinetics, and H. pylori lipopolysaccharide, as well as the roles of several bacterial genes (cagA, cagT, vacA and dupA) as virulence factors in gastric cancer, and the gastrokine-1 protein in cancer progression.
Author: L G Capellan
Publisher: Independently Published
ISBN:
Category :
Languages : en
Pages : 256
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Book Description
Break Free from Gastritis and Get Back to Enjoying Your Life Fully―Your complete guide One of the main reasons why gastritis-especially chronic cases-is often difficult to cure is that an effective treatment option does not exist. Eliminating gastritis and its annoying symptoms calls for more than acid-blocking medications. It requires a comprehensive treatment approach that tackles the root cause and provides a real solution to the problem―which is exactly what this book is all about. The Gastritis Healing Book offers a completely new treatment approach that incorporates precise advice and recommendations about the changes you should make in your diet, habits, and lifestyle, in order to heal your stomach. Inside this book, you will discover: A complete step-by-step healing program that provides the tools you need to fight gastritis effectively. A gastritis overview that teaches you everything you need to know about gastritis, including the main factors that might be holding you back from healing. A seven-day meal plan that removes the stress of dietary change with planned meals, a shopping list, and meal prep advice. More than 50 gastritis-friendly, gluten-free, and dairy-free recipes for breakfast, lunch, dinner, and snacks, so that you can also create your own meal plan and stick to the gastritis diet long after the one-week meal plan is over. A list of science-backed natural supplements and remedies that will help you speed up the healing process of your stomach. With The Gastritis Healing Book, you'll be on the road to a healthier, happier, and symptom-free life!
Author: Gerard E. Mullin
Publisher: Oxford University Press
ISBN: 0190933062
Category : Medical
Languages : en
Pages : 464
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Book Description
Digestive complaints have become increasingly common. Recent statistics show that gastrointestinal complaints account for nearly a third of all visits to primary care doctors and that nearly one in two Americans suffer from digestive disease. Millions more suffer from conditions such as migraine headaches, arthritis, mood disorders, chronic fatigue, asthma, allergies, and menstrual dysfunction, which are all related to a disorder in digestive health. Despite the evidence in support of integrative approaches to treatment and prevention of digestive symptoms, these approaches are largely overlooked in treating gastrointestinal disorders. Rather, treatment plans tend to be exclusively pharmacologically based and have appreciable toxicity. Integrative Gastroenterology, Second edition, is a comprehensive guide to helping health care practitioners understand and appreciate how to manage patients with gastrointestinal conditions integrating conventional and complimentary approaches. This text reviews the latest advances in science and research with regards to the gut microbiome, physiology, and interconnections between the gut and other organ systems. Coverage includes a diverse range of treatment methods, such as probiotics, meditation, massage, yoga, supplements, special diets, energy medicine, homeopathy, and acupuncture, as well as a special section devoted to mind-body medicine in digestive health and disease. In discussing unconventional treatments, the authors address many of the controversies that surround the remedies.
Author: Vijaya B. Reddy
Publisher: Elsevier Health Sciences
ISBN: 0323261973
Category : Medical
Languages : en
Pages : 1087
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Book Description
Confidently sign out your most complex and challenging cases with the updated edition of Differential Diagnosis in Surgical Pathology. Widely used by residents and practicing pathologists alike, this comprehensive medical reference provides brief, bulleted descriptions of both common and rare disorders, integrating excellent illustrative examples of the pathology with selected references. It's the perfect go-to resource to have by your microscope! Quickly access essential information through concise, bulleted text; a consistent approach to diagnosis and interpretation; and a comprehensive yet manageable size. Formulate an accurate diagnosis with coverage of all of the relevant ancillary diagnostic techniques, and ensure every diagnostic possibility is explored with help from quick checklists throughout. Make informed decisions when delineating one disease from another with discussions covering all of the major organ systems. Understand what diagnostic criteria to consider or exclude with expert "pearls" and practical tips throughout. Take advantage of extensive updates on tumor classifications and diseases, as well as expanded coverage of medical renal pathology. Stay abreast of the latest developments in molecular testing, including diagnostics, biomarkers, and targeted therapies, for entities such as the breast, lung, gastrointestinal tract, and melanoma. View over 1,350 full-color macro and microphotographs that provide a realistic basis for comparison to what you see under the microscope. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.
Author: Bruna Maria Roesler
Publisher: BoD – Books on Demand
ISBN: 1789846641
Category : Medical
Languages : en
Pages : 127
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Book Description
The isolation and identification of Helicobacter pylori as the cause of gastrointestinal diseases had major implications for public health and led to curative treatments that reduced suffering from many acute and chronic conditions. Although alternative therapies have been used to improve eradication, current treatments still rely on a combination of antimicrobial agents often associated with antisecretory agents, such as proton pump inhibitors. In this book there is a comprehensive overview by contributors on H. pylori infection in diverse areas, including a general overview of H. pylori infection, and discussions about the principal therapeutic regimens of bacterium eradication, considering antimicrobial resistance. Also, certain aspects of autoimmune gastritis, an important condition that has been related to microorganism infection, is also considered. H. pylori is clearly a very interesting bacterium and great studies and discussions about all its aspects are welcomed by the medical and scientific communities.
Author: P. Malfertheiner
Publisher: S. Karger AG (Switzerland)
ISBN: 9783318026320
Category :
Languages : en
Pages : 0
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Book Description
This special topic issue of 'Digestive Diseases' contains contributions discussing the subject in-depth. 'Digestive Diseases' is a well-respected, international peer-reviewed journal in Gastroenterology. Special topic issues are included in the subscription.
Author: Peter R McNally
Publisher: Elsevier Health Sciences
ISBN: 0323082785
Category : Medical
Languages : en
Pages : 638
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Book Description
GI/Liver Secrets Plus, 4th Edition, by Peter R. McNally, DO, FACP, FACG - a volume in the popular Secrets Series® - uses a convenient Q&A approach to provide rapid reference and review of today's most common GI and liver disorders and their management. An expanded size and layout, user-friendly two-color page layout, question-and-answer approach, and list of the "Top 100 GI/Liver Secrets" make it a perfect concise board review tool and a handy clinical reference. Updated coverage throughout equips you with all of the most current and essential knowledge in the field. Uses bulleted lists, tables, boxes, short answers, and a highly detailed index to expedite reference. Includes Key Points and memory aids in each chapter that make it perfect for board review or clinical reference. Covers all of today's most common GI and liver disorders and their management. Features the new "Secrets PLUS" format - with an expanded size and layout, more information, and more visual elements - for easier review and an overall enhanced reference experience. Contains new images and illustrations to provide more detail and offer a clearer picture of what is seen in practice. Incorporates revisions throughout to provide you with an up-to-date overview of gastroenterology and hepatology, including new chapters on Esophageal and Stomach Pathology, Pathology of the Lower GI Tract, Gastroesophageal Reflux and Esophageal Hernias, and Surgery of Achalasia and Esophageal Cancer. Offers reorganized and expanded sections covering the bowels and colon for more specific and easier reference: Small and Large Bowel Disorders; Colon Disorders; and General Symptoms and Conditions.
