Initiation and Promotion in Skin Or Liver Neoplasia PDF Download
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Author: Edward B. Ilgren
Publisher: CRC Press
ISBN: 9780849344077
Category : Medical
Languages : en
Pages : 936
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Book Description
Initiation and Promotion in Skin or Liver Neoplasia is the only source of its kind that presents a comprehensive compilation of in vivo initiation/promotion studies that involve neoplastic changes in the skin or liver of experimental animals. The book surveys world literature over the past 65 years from almost 2,000 original studies covering nearly 200 journals in 9 languages. Publications reviewed consist of primary peer-reviewed papers, as well as those abstracts, meeting reports, and review articles, containing original data. Papers measuring both pre-neoplastic or neoplastic changes are included. The summaries for each study included in the book are highly formatted resumes that have four principal components which indicate: 1) What was done in the study; 2) How the study was done (e.g, methods); 3) The precise results obtained; 4) Individual critiques using GLP (Good Lab Practice) standards. Initiation and Promotion in Skin or Liver Neoplasia provides an indispensable abstracted reference resource for scientists, toxicologists, cancer researchers, litigators, regulators, environmentalists, policy analysts, and industry-based investigators.
Author: Edward B. Ilgren
Publisher: CRC Press
ISBN: 9780849344077
Category : Medical
Languages : en
Pages : 936
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Book Description
Initiation and Promotion in Skin or Liver Neoplasia is the only source of its kind that presents a comprehensive compilation of in vivo initiation/promotion studies that involve neoplastic changes in the skin or liver of experimental animals. The book surveys world literature over the past 65 years from almost 2,000 original studies covering nearly 200 journals in 9 languages. Publications reviewed consist of primary peer-reviewed papers, as well as those abstracts, meeting reports, and review articles, containing original data. Papers measuring both pre-neoplastic or neoplastic changes are included. The summaries for each study included in the book are highly formatted resumes that have four principal components which indicate: 1) What was done in the study; 2) How the study was done (e.g, methods); 3) The precise results obtained; 4) Individual critiques using GLP (Good Lab Practice) standards. Initiation and Promotion in Skin or Liver Neoplasia provides an indispensable abstracted reference resource for scientists, toxicologists, cancer researchers, litigators, regulators, environmentalists, policy analysts, and industry-based investigators.
Author: Elizabeth K. Weisburger
Publisher: Springer Science & Business Media
ISBN: 9400925263
Category : Medical
Languages : en
Pages : 210
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Book Description
but also the possibility of intervention in specific stages. In Human behavior, including stress and other factors, plays an important role in neoplasia, although too little is known addition, variables which affect cancer development as well on the reasons for such development. Carcinogens, which as some endogenous factors can be better delineated help initiate the neoplastic process, may be either synthetic through such investigations. The topics of this volume encompass premalignant non or naturally-occurring. Cancer causation may be ascribed to invasive lesions, species-specific aspects of carcinogenicity, certain chemicals, physical agents, radioactive materials, viruses, parasites, the genetic make-up of the organism, and radiation, viruses, a quantum theory of carinogenesis, onco bacteria. Humans, eumetazoan animals and vascular plants genes, and selected environmental carcinogens. are susceptible to the first six groups of cancer causes, whe reas the last group, bacteria, seems to affect only vascular plants. Neoplastic development may begin with impairment ofJmdy defenses by a toxic material (carcinogen) which acts as an initiator, followed by promotion and progression to an overt neoplastic state. Investigation of these processes Series Editor Volume Editor allows not only a better insight into the mechanism of action Hans E. Kaiser Elizabeth K. Weisburger vii ACKNOWLEDGEMENT Inspiration and encouragement for this wide ranging project on cancer distribution and dissemination from a comparative biological and clinical point of view, was given by my late friend E. H. Krokowski.
Author: Carey N. Pope
Publisher: Academic Press
ISBN: 0128136022
Category : Technology & Engineering
Languages : en
Pages : 644
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Book Description
An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from "simple” molecular systems, to complex human communities, with expertise from a spectrum of interacting disciplines. Chapters are written by specialists within a given subject, such as a chemical engineer, nutritional scientist, or a microbiologist, so subjects are clearly explained and discussed within the toxicology context. Many chapters are comparative across species so that students in ecotoxicology learn mammalian toxicology and vice versa. Specific citations, further reading, study questions, and other learning features are also included. The book allows students to concurrently learn concepts in both biomedical and environmental toxicology fields, thus better equipping them for the many career opportunities toxicology provides. This book will also be useful to those wishing to reference how disciplines interact within the broad field of toxicology.
Author:
Publisher:
ISBN:
Category : Carcinogenesis
Languages : en
Pages : 432
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Book Description
Author: Bharat B. Aggarwal
Publisher: Springer
ISBN: 3034808372
Category : Medical
Languages : en
Pages : 489
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Book Description
This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.
Author: Claudia Mierke
Publisher: Iph001
ISBN: 9780750317511
Category : Science
Languages : en
Pages : 500
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Book Description
This revised second edition is improved linguistically with multiple increases of the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion, and the active role of the tumor stroma in regulating cell invasion.
Author: National Research Council
Publisher: Legare Street Press
ISBN: 9781015691629
Category : History
Languages : en
Pages : 0
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Book Description
This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Author: A.E. Sirica
Publisher: Springer Science & Business Media
ISBN: 1468455230
Category : Medical
Languages : en
Pages : 591
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Book Description
This book is directed primarily to advanced graduate and medical students, postdoctoral trainees, and established investigators having basic research interests in neoplasia. Its content is based in part on the lecture outlines and selected histopathology laboratory components of an advanced course entitled The Pathobiology of Experimental Animal and Human Neoplasia, developed by me for the Experimental Pathology Curriculum of the Department of Pathology at the Medical College of Virginia. In this regard, an effort has been made to integrate pathology with carcinogenesis, genetics, biochemistry, and cellular and molecular biology in order to present a comprehensive and current view of the neoplastic process. For focus, emphasis is mainly being placed on the neoplastic cells themselves, and not on associated host-mediated responses. It ishoped that this book will accomplish its purpose of providing students and researchers who already possess strong but diverse basic science backgrounds with unifying concepts in tumor pathobiology, so as to stimulate new research aimed at furthering our understanding of neoplastic disease. I wish to express my appreciation and heartfelt thanks to the authors, whose individual ranges of expertise and research experience clearly bring to their respective chapters unique perspectives that easily transcend any redundancy that may be present. In addition, I am grateful to Drs. George Vennart, Saul Kay, and Fred Meier, and to Ms. Connie Wilkerson of the Department of Pathology at MCV, for their helpful comments and their review of some of the material.
Author:
Publisher:
ISBN:
Category : Aryl groups
Languages : en
Pages : 276
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Book Description
Author: Raymond W. Ruddon M.D.
Publisher: Oxford University Press
ISBN: 0199748152
Category : Medical
Languages : en
Pages : 569
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Book Description
A thorough yet concise account of cancer biology, this book emphasizes the cellular and molecular mechanisms involved in the transformation of normal into malignant cells, the invasiveness of cancer cells into host tissues, and the metastatic spread of cancer cells in the host organism. It also defines the fundamental pathophysiological changes that occur in tumor tissue and in the host animal or patient. The approach throughout the book is to discuss the historical development of a field, citing the key experimental advances to the present day, and to evaluate the current evidence that best supports or rules out concepts of the molecular and cellular mechanisms regulating cancer cell behavior. For all the areas of fundamental cancer research, an effort has been made to relate basic research findings to the clinical disease states. The book is well illustrated with schematic diagrams and actual research data to demonstrate points made in the text, and there is an extensive, up-to-date bibliography. In this revision, Dr. Ruddon has organized his text to provide more integrated discussion of the many topics covered in the third edition. At the same time, he has included much new material on molecular genetics and genetic diagnosis (e.g., DNA microarrays to mark tumors), RNA interference, stem cells, cell cycle regulation, angiogenesis, etc.
