Treatment Strategy for Unexplained Infertility and Recurrent Miscarriage

Treatment Strategy for Unexplained Infertility and Recurrent Miscarriage PDF Author: Keiji Kuroda
Publisher: Springer
ISBN: 9811086907
Category : Medical
Languages : en
Pages : 125

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Book Description
This book offers a highly informative guide to treating unexplained infertility and recurrent miscarriage (RM). In particular, it provides detailed treatment strategies for infertility or RM derived from uterine circumstance such as chronic endometritis and perturbation of endometrial decidualization, as well as maternal immunological rejection of an embryo as semi-allograft. Unexplained infertility refers to those types that cannot be detected by the general screening test. The causes are sometimes detected in the course of treatment with assisted reproductive technology including IVF. However, some unexplained infertility is intractable even after intracytoplasmic sperm injection or repeated implantation of morphologically suitable embryos. Patients with unexplained RM also have a high likelihood of undetectable risk factors of miscarriage. As a result, gynecologists often repeatedly provide these couples with general treatments for infertility and miscarriage or even discontinue treatment because they cannot detect the reason, which places serious financial, physical and mental burdens on the couples affected. This book offers gynecologists essential insights into the pathological condition of unexplained infertility and RM, equipping them to identify it, explain it to patients, and consider further examinations and more aggressive fertility treatments.

Treatment Strategy for Unexplained Infertility and Recurrent Miscarriage

Treatment Strategy for Unexplained Infertility and Recurrent Miscarriage PDF Author: Keiji Kuroda
Publisher: Springer
ISBN: 9811086907
Category : Medical
Languages : en
Pages : 125

Get Book Here

Book Description
This book offers a highly informative guide to treating unexplained infertility and recurrent miscarriage (RM). In particular, it provides detailed treatment strategies for infertility or RM derived from uterine circumstance such as chronic endometritis and perturbation of endometrial decidualization, as well as maternal immunological rejection of an embryo as semi-allograft. Unexplained infertility refers to those types that cannot be detected by the general screening test. The causes are sometimes detected in the course of treatment with assisted reproductive technology including IVF. However, some unexplained infertility is intractable even after intracytoplasmic sperm injection or repeated implantation of morphologically suitable embryos. Patients with unexplained RM also have a high likelihood of undetectable risk factors of miscarriage. As a result, gynecologists often repeatedly provide these couples with general treatments for infertility and miscarriage or even discontinue treatment because they cannot detect the reason, which places serious financial, physical and mental burdens on the couples affected. This book offers gynecologists essential insights into the pathological condition of unexplained infertility and RM, equipping them to identify it, explain it to patients, and consider further examinations and more aggressive fertility treatments.

Clinical Gynecology

Clinical Gynecology PDF Author: Eric J. Bieber
Publisher: Cambridge University Press
ISBN: 1107040396
Category : Medical
Languages : en
Pages : 1127

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Book Description
Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.

Immunology of Recurrent Pregnancy Loss and Implantation Failure

Immunology of Recurrent Pregnancy Loss and Implantation Failure PDF Author: Joanna Kwak-Kim
Publisher: Elsevier
ISBN: 0323908055
Category : Medical
Languages : en
Pages : 456

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Book Description
Immunology of Recurrent Pregnancy Loss provides doctors and immunologists with the information they need to help couples who experience recurrent pregnancy losses. Sections cover unexplained infertility, repeated in vitro fertilization, embryo transfer failures, history of second or third trimester pregnancy losses of unknown cause, or pregnancy with a history of or active autoimmune and/or alloimmune disease. Reproductive failure (RF), including recurrent pregnancy losses (RPL) and repeated implantation failures (RIF) is rather a syndrome than a disease caused by multiple etiologies, such as anatomical, endocrine, genetic, infectious, immunological, thrombotic and unexplained etiologies, hence this book strives to present the latest information. In 27 chapters, divided in 5 sections, the book introduces the current update of reproductive immunology topics in RF and provides systematic diagnostic guidelines, systemic and immune etiologies and therapeutic approaches. Provides detailed immunological background for understanding the etiology and management of reproduction failure Evaluates various immunological factors involved in the pathogenesis and management of reproduction failure Gives insights into various immunological and therapeutic approaches for reproduction failure

Not Broken

Not Broken PDF Author: Lora Shahine
Publisher:
ISBN: 9780998714608
Category : Fetal death
Languages : en
Pages : 148

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Book Description
Not Broken is a comprehensive, evidence-based but easy-to-read guide for anyone who wants to understand all aspects of miscarriage and recurrent pregnancy loss. Whether you are a patient struggling with miscarriages or a medical provider caring for patients with recurrent pregnancy loss, you will learn something from this resource. Dr. Shahine explains not only a typical Western medicine approach to evaluation and treatment for miscarriage but also includes Eastern approaches to care, lifestyle factors that will decrease your risk of miscarriage, and the emotional impact of recurrent pregnancy loss. You will finish this book feeling more empowered to be an advocate for your care and more hopeful than ever to continue towards your family goals. "I have one word to describe this fabulous book: FINALLY. Women with recurrent pregnancy loss have been needing this book for years." - Dr. Alice Domar, associate professor of obstetrics, gynecology, and reproductive biology at Harvard Medical School and author of Conquering Infertility and Finding Calm for the Expectant Mom

Immunology of Pregnancy

Immunology of Pregnancy PDF Author: Udo R. Markert
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805579705
Category : Medical
Languages : en
Pages : 201

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Book Description
This book presents the discipline of immunology which studies a unique physiological phenomenon contradicting many of the generally established rules in the field: immunology of pregnancy. It provides a wide overview of the current research of this topic. Prominent and leading international groups contributed by reviewing the most significant findings in the field.

Polycystic Ovary Syndrome

Polycystic Ovary Syndrome PDF Author: Andrea Dunaif
Publisher: Springer Science & Business Media
ISBN: 1597451088
Category : Medical
Languages : en
Pages : 361

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Book Description
This volume includes the latest diagnostic criteria for PCOS and comprises the most up-to-date information about the genetic features and pathogenesis of PCOS. It critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. The book also discusses additional familial phenotypes of PCOS and their potential genetic basis. All four editors of this title are extremely prominent in the field of PCOS.

Clinical Gynaecology

Clinical Gynaecology PDF Author: T. F. Kruger
Publisher: Juta and Company Ltd
ISBN: 9780702173059
Category : Medical
Languages : en
Pages : 716

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Book Description
Presenting the basis for gynecological studies in South Africa, this comprehensive examination, compiled by 32 leaders in the field, describes the history and basics of gynecology—including genetics, embryology, anatomy, physiology, and cytology bioethics. Incorporating information on the latest diagnostic and therapeutic procedures, HIV/AIDS, abuse and violence against women, and access to gynecological data via electronic media, this third edition includes eight new chapters, a DVD that shows live techniques and procedures, and a quick-reference guide summarizing the salient points of each chapter. An invaluable resource for undergraduates, postgraduate students, and practicing physicians, the topics covered in this authoritative handbook apply not only to sub-Saharan Africa but to any developing community.

Fertility Breakthrough

Fertility Breakthrough PDF Author: Gabriela Rosa
Publisher:
ISBN: 9781781333631
Category : Health & Fitness
Languages : en
Pages : 0

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Book Description
Fertility Breakthrough is an indispensable guide for those who wish to overcome infertility and recurrent miscarriage. Written by world-renowned fertility specialist, Gabriela Rosa, the advice in this book has helped thousands of couples overcome infertility and recurrent miscarriage when other treatments have failed.

Early Pregnancy Loss

Early Pregnancy Loss PDF Author: Richard W. Beard
Publisher: Springer
ISBN: 9783540195306
Category : Medical
Languages : en
Pages : 442

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Book Description
The first few months of any pregnancy are of supreme importance to the success of that pregnancy. This statement is so obvious as to be almost a platitude, yet it must be said that no aspect of pregnancy has been more neglected in the human than the first three months. Little is known of the morphological changes that occur at that time and our knowledge of the mechanisms that control this vital stage of pregnancy is almost non-existent. The explanation for this neglect of what is an obvious area for study is the difficulty of obtaining normal material. It is rare to have material to study from a healthy first trimester pregnancy and the study by Hertig and Rock!l) of early conception found by chance in hysterectomy speci mens must be unique. The information that we do have about early pregnancy is mostly gained from animal studies or single miscarriages in humans. Chromosomal defects are common but are not an explanation for the majority of recurrent miscarriages. Obstetricians have hypothesised many causes for this condition and have deve loped numerous metQods for treating it, but the studies have been poorly con trolled so that our understanding of the cause(s) has not advanced. Treatment of women with a history of recurrent miscarriage by paternal leuco cyte infusion (immunotherapy) may be yet another form of treatment that is hailed as a new advance only to be rejected when subject to rigorous testing.

Endometrial Gene Expression

Endometrial Gene Expression PDF Author: Joanne Kwak-Kim
Publisher: Springer
ISBN: 9783030285869
Category : Health & Fitness
Languages : en
Pages : 0

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Book Description
The endometrium goes through cyclical changes under the influence of hormones, and immune effectors in the endometrium change their populations cyclically as well. Dynamic changes in immune effectors determine endometrial cytokine and chemokine milieus and, consequently, the endometrial immune response. Endometrial immune responses have been shown to be important for trophoblast invasion and early pregnancy. Indeed, dysregulated endometrial inflammatory immune responses are associated with reproductive failures, such as recurrent pregnancy losses, repeated implantation failure, and gynecological diseases with oncogenic potential. Hence, the investigation of endometrial gene expression may predict infertility, gynecological and oncological conditions. This book presents the state of the art in endometrial gene expression as well as recent developmental findings relating to reproduction and reproductive disorders. It begins with a review of the genetic regulation of urogenital tract formation and molecular mechanism underlying the physiology of menstrual cycle before moving on to the current and emerging technological advances in molecular biology. Endometrial gene expressions of immune inflammatory conditions, viral infection, metabolic and nutritional conditions, and reproductive disorders are then presented in following chapters. Examples of the use and interpretation of gene expression in clinical scenarios including recurrent pregnancy losses, infertility and multiple implantation failures are presented with currently available endometrial gene analysis. Utilizing the latest evidence and clinical guidelines, Endometrial Gene Expression will be a cutting-edge resource for gynecologist, reproductive immunologist, reproductive endocrinologists, obstetrician, maternal fetal medicine specialist and other health care providers in the field of reproductive medicine.