In Vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials

In Vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials PDF Author: Toru Takebayashi
Publisher: Springer Nature
ISBN: 9811384339
Category : Medical
Languages : en
Pages : 223

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Book Description
This edited volume discusses the short-term inhalation study (STIS) and intratracheal administration, the two major in vivo inhalation-toxicity screening methods, which play an important role in efficient hazard evaluation. It also provides a general overview of the inhalation toxicity of nanomaterials and related issues. For each screening method, it provides up-to-date information on the test procedures, interpretation of the test results, useful applications, and related technologies. In view of the increasing variety of nanomaterials in practical use, the book offers a basis for building a framework for grouping and read-across assessments of nanomaterials. With contributions by academic and industrial experts, In vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials is a pragmatic reference resource for readers who are responsible for assessing the safety of nanomaterials in R&D and business, as well as researchers.

In Vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials

In Vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials PDF Author: Toru Takebayashi
Publisher: Springer Nature
ISBN: 9811384339
Category : Medical
Languages : en
Pages : 223

Get Book Here

Book Description
This edited volume discusses the short-term inhalation study (STIS) and intratracheal administration, the two major in vivo inhalation-toxicity screening methods, which play an important role in efficient hazard evaluation. It also provides a general overview of the inhalation toxicity of nanomaterials and related issues. For each screening method, it provides up-to-date information on the test procedures, interpretation of the test results, useful applications, and related technologies. In view of the increasing variety of nanomaterials in practical use, the book offers a basis for building a framework for grouping and read-across assessments of nanomaterials. With contributions by academic and industrial experts, In vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials is a pragmatic reference resource for readers who are responsible for assessing the safety of nanomaterials in R&D and business, as well as researchers.

In Vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials

In Vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials PDF Author:
Publisher:
ISBN: 9789811384349
Category : Nanostructured materials
Languages : en
Pages : 221

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Book Description
This edited volume discusses the short-term inhalation study (STIS) and intratracheal administration, the two major in vivo inhalation-toxicity screening methods, which play an important role in efficient hazard evaluation. It also provides a general overview of the inhalation toxicity of nanomaterials and related issues. For each screening method, it provides up-to-date information on the test procedures, interpretation of the test results, useful applications, and related technologies. In view of the increasing variety of nanomaterials in practical use, the book offers a basis for building a framework for grouping and read-across assessments of nanomaterials. With contributions by academic and industrial experts, In vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials is a pragmatic reference resource for readers who are responsible for assessing the safety of nanomaterials in R&D and business, as well as researchers.

Nanotechnologies

Nanotechnologies PDF Author:
Publisher:
ISBN:
Category : Nanoparticles
Languages : en
Pages : 30

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Book Description


Modelling the Toxicity of Nanoparticles

Modelling the Toxicity of Nanoparticles PDF Author: Lang Tran
Publisher: Springer
ISBN: 3319477544
Category : Medical
Languages : en
Pages : 360

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Book Description
In today’s nanotechnology and pharmaceutical research, alternative toxicology testing methods are crucial for ethically and commercially sound practice. This book provides practical guidelines on how to develop and validate quantitative nanostructure-toxicity relationship (QNTR) models, which are ideal for rapidly exploring the effects of a large number of variables in complex scenarios. Through contributions by academic, industrial, and governmental experts, Modelling the Toxicity of Nanoparticles delivers clear instruction on these methods and their integration and use in risk assessment. Specific topics include the physico-chemical characteristics of engineered nanoparticles, nanoparticle interactions, in vivo nanoparticle processing, and more. A much-needed practical guide, Modelling the Toxicity of Nanoparticles is a key text for researchers as well as government and industry regulators.

Nanotoxicology

Nanotoxicology PDF Author: Nancy A. Monteiro-Riviere
Publisher: CRC Press
ISBN: 1482203871
Category : Medical
Languages : en
Pages : 516

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Book Description
Since the first publication of this book in 2007, the field of nanoscience and nanomedicine continues to grow substantially. This second edition, Nanotoxicology: Progress toward Nanomedicine, enlists internationally recognized experts to document the continuing development and rationale for the safe design of engineered nanomaterials (ENM). This includes new improved characterization endpoints, screening, and detection methods for in vitro and in vivo toxicity testing. These tools also contribute greatly to nanosafety research applied to nanomedicines. Topics include The impacts of nanotechnology on biomedicine, including functionalization for tissue-specific targeting, the biointeractions of multifunctional nanoparticle-based therapy, and the ability to control specific physicochemical properties of nanoparticles The requirements for proper detection, measurement, and assessment both for workplace exposure and in consumer products—with a focus on potential health and safety implications Predictive modeling, using quantitative nanostructure activity relationships to predict the pharmacokinetics and biodistribution of nanomaterials in the body Specific methodologies, imaging, and techniques to assess nanomaterials from the manufacturing process to nanomedicine applications Tools for assessing nanoparticle toxicity and the limitations of detection methods for assessing toxicity in both in vivo and in vitro systems and at the single cell and tissue levels Toxicity of nanomaterials to specific organ systems, cell–based targeting to tumors, and other biomedical applications The difficulty of conducting risk assessments and the need for addressing knowledge gaps, especially with long-term studies A roadmap for future research The development of nanotechnology-based products must be complemented with appropriate validated methods to assess, monitor, manage, and reduce the potential risks of ENM to human health and the environment. This volume provides a cogent survey of advances in this area by a well-respected and diverse group of international scientists.

Nanotechnologies. Compilation and Description of Toxicological Screening Methods for Manufactured Nanomaterials

Nanotechnologies. Compilation and Description of Toxicological Screening Methods for Manufactured Nanomaterials PDF Author: British Standards Institute Staff
Publisher:
ISBN: 9780580744853
Category :
Languages : en
Pages : 42

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Book Description
Nanotechnology, Nanomaterials, Nanoparticles, Fibres, Particle size measurement, Vocabulary, Terminology

Particle Toxicology

Particle Toxicology PDF Author: Ken Donaldson
Publisher: CRC Press
ISBN: 1420003143
Category : Medical
Languages : en
Pages : 462

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Book Description
Exposure to particles in industry and mining and from accidental anthropogenic sources constitutes an ongoing threat. Most recently nanoparticles arising from advances in technology are exposing a wider population to pathogenic stimuli. The effects of inhaled particles are no longer confined to the lung as nanoparticles have the potential to transl

Nanotechnologies. Characterization of Nanoparticles in Inhalation Exposure Chambers for Inhalation Toxicity Testing

Nanotechnologies. Characterization of Nanoparticles in Inhalation Exposure Chambers for Inhalation Toxicity Testing PDF Author: British Standards Institute Staff
Publisher:
ISBN: 9780580659362
Category :
Languages : en
Pages : 30

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Book Description
Nanotechnology, Nanomaterials, Nanoparticles, Toxic materials, Dangerous materials, Cytotoxicity tests, Respiratory system, Aerosols, Particulate air pollutants, Particle size distribution, Composition, Test equipment

Nanotechnologies

Nanotechnologies PDF Author:
Publisher:
ISBN:
Category : Nanoparticles
Languages : en
Pages : 22

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Book Description


Nanotechnologies. Generation of Metal Nanoparticles for Inhalation Toxicity Testing Using the Evaporation/Condensation Method

Nanotechnologies. Generation of Metal Nanoparticles for Inhalation Toxicity Testing Using the Evaporation/Condensation Method PDF Author: British Standards Institute Staff
Publisher:
ISBN: 9780580613982
Category :
Languages : en
Pages : 34

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Book Description
Nanotechnology, Nanomaterials, Nanoparticles, Metals, Toxic materials, Dangerous materials, Cytotoxicity tests, Respiratory system, Specimen preparation, Evaporation, Condensation, Aerosols, Particulate air pollutants