Diagnostics at a Crossroads: Navigating IVD Regulation in a Changing Environment

Diagnostics at a Crossroads: Navigating IVD Regulation in a Changing Environment PDF Author: Jeffrey Gibbs
Publisher:
ISBN: 9781935065890
Category :
Languages : en
Pages :

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Diagnostics at a Crossroads: Navigating IVD Regulation in a Changing Environment

Diagnostics at a Crossroads: Navigating IVD Regulation in a Changing Environment PDF Author: Jeffrey Gibbs
Publisher:
ISBN: 9781935065890
Category :
Languages : en
Pages :

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Book Description


The selection and use of essential in vitro diagnostics

The selection and use of essential in vitro diagnostics PDF Author:
Publisher: World Health Organization
ISBN: 9240019103
Category : Medical
Languages : en
Pages : 380

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Rapid Expert Consultations on the COVID-19 Pandemic

Rapid Expert Consultations on the COVID-19 Pandemic PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309676908
Category : Medical
Languages : en
Pages : 81

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Book Description
In response to a request from the Office of Science and Technology Policy and the Office of the Assistant Secretary for Preparedness and Response, the National Academies of Sciences, Engineering, and Medicine convened a standing committee of experts to help inform the federal government on critical science and policy issues related to emerging infectious diseases and other 21st century health threats. This set of Rapid Expert Consultations are the first of their kind and represent the best evidence available to the Committee at the time each publication was released. The science on these issues is continually evolving, and the scientific consensus the Committee reaches on these topics will likely evolve with it. The standing committee includes members with expertise in emerging infectious diseases, public health, public health preparedness and response, biological sciences, clinical care and crisis standards of care, risk communication, and regulatory issues.

Pandemics: Insurance and Social Protection

Pandemics: Insurance and Social Protection PDF Author: María del Carmen Boado-Penas
Publisher: Springer Nature
ISBN: 3030783340
Category : Applied mathematics
Languages : en
Pages : 314

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Book Description
This open access book collects expert contributions on actuarial modelling and related topics, from machine learning to legal aspects, and reflects on possible insurance designs during an epidemic/pandemic. Starting by considering the impulse given by COVID-19 to the insurance industry and to actuarial research, the text covers compartment models, mortality changes during a pandemic, risk-sharing in the presence of low probability events, group testing, compositional data analysis for detecting data inconsistencies, behaviouristic aspects in fighting a pandemic, and insurers' legal problems, amongst others. Concluding with an essay by a practicing actuary on the applicability of the methods proposed, this interdisciplinary book is aimed at actuaries as well as readers with a background in mathematics, economics, statistics, finance, epidemiology, or sociology.

Molecular Allergy Diagnostics

Molecular Allergy Diagnostics PDF Author: Jörg Kleine-Tebbe
Publisher: Springer
ISBN: 3319424998
Category : Medical
Languages : en
Pages : 537

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Book Description
This book, based on a recent German publication, offers an overview of basic data and recent developments in the groundbreaking field of molecular allergology. It comprehensively explores the origin and structure of single allergen molecules ("components") and their utility in improving the management of type I, IgE-mediated allergic reactions and disorders like allergic respiratory diseases, food allergies, and anaphylaxis. Highly specific testing, called component-resolved diagnostics, aims to identify and utilize single molecules. Over 200 single allergens from plant or animal sources have been applied to single or multiplex laboratory testing for the presence of allergen-specific IgE. This leap in assay sensitivity and specificity has led to three major advances in patient management: discrimination between primary allergic sensitization and complex cross-reactivity, recognition of IgE profiles for certain allergens and identification of patients most likely to benefit from allergen-specific immunotherapy. The book discusses in detail the benefits and limitations of this 21st century technology, and offers suggestions for the use of molecular allergology in routine clinical practice. It is a “must read” for physicians treating allergic patients as well as scientists interested in natural allergic molecules and their interactions with the human immune system.

Viruses

Viruses PDF Author: Susan Payne
Publisher: Elsevier
ISBN: 0323984762
Category : Science
Languages : en
Pages : 439

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Book Description
Viruses: From Understanding to Investigation, Second Edition presents the definitions and unique characteristics of viruses. The book includes major topics such as virus lifecycle, structure, taxonomy, evolution, history, host-virus interactions, and methods to study. In addition, the book assesses the connections between the aforementioned topics and provides an integrated approach and in-depth understanding of how viruses work. The new edition also provides an expanded methods chapter containing new information on deep sequencing for in virus identification, mathematical formulas to calculate titers and a description of quantitiative PCR for enumerating viruses. The vaccine chapter has been updated to include vaccine efficacy, mRNA vaccines and SARS-CoV-2 vaccine development. The viral pathogenesis chapter has been expanded to include mechanisms of virally induced cancers. Viral taxonomy sections have been updated and chapters revised to accommodate new virus family designations. New chapters include nucleocytoplasmic viruses (very large DNA viruses), replication of viroids and COVID-19/SARS-CoV-2. - Employs a comparative strategy to emphasize unique structural and molecular characteristics that inform transmission, disease processes, vaccine strategies, and host responses - Presents a review of host cell, molecular biology, and the immune system - Features topical areas of research, including genomics in virus discovery, the virome, and beneficial interactions between viruses and their hosts - Includes text boxes throughout with experimental approaches used by virologists - Covers learning objectives in each chapter

Medical Devices Law and Regulation Answer Book

Medical Devices Law and Regulation Answer Book PDF Author: Suzan Onel
Publisher:
ISBN: 9781402441622
Category : Medical instruments and apparatus
Languages : en
Pages : 0

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Book Description


CDC Yellow Book 2018: Health Information for International Travel

CDC Yellow Book 2018: Health Information for International Travel PDF Author: Centers for Disease Control and Prevention CDC
Publisher: Oxford University Press
ISBN: 0190628634
Category : Medical
Languages : en
Pages : 705

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Book Description
THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.

Learning from SARS

Learning from SARS PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309182158
Category : Medical
Languages : en
Pages : 376

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Book Description
The emergence of severe acute respiratory syndrome (SARS) in late 2002 and 2003 challenged the global public health community to confront a novel epidemic that spread rapidly from its origins in southern China until it had reached more than 25 other countries within a matter of months. In addition to the number of patients infected with the SARS virus, the disease had profound economic and political repercussions in many of the affected regions. Recent reports of isolated new SARS cases and a fear that the disease could reemerge and spread have put public health officials on high alert for any indications of possible new outbreaks. This report examines the response to SARS by public health systems in individual countries, the biology of the SARS coronavirus and related coronaviruses in animals, the economic and political fallout of the SARS epidemic, quarantine law and other public health measures that apply to combating infectious diseases, and the role of international organizations and scientific cooperation in halting the spread of SARS. The report provides an illuminating survey of findings from the epidemic, along with an assessment of what might be needed in order to contain any future outbreaks of SARS or other emerging infections.

Socio-Life Science and the COVID-19 Outbreak

Socio-Life Science and the COVID-19 Outbreak PDF Author: Makoto Yano
Publisher: Springer Nature
ISBN: 9811657270
Category : COVID-19 Pandemic, 2020-
Languages : en
Pages : 372

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Book Description
This open access book presents the first step towards building socio-life science, a field of science investigating humans in such a way that both social and life-scientific factors are integrated. Because humans are both living and social creatures, a human action can never be understood fully without knowing both the biological traits of a person and the social scientific environments in which he exists. With this consideration, the editors of this book have initiated a research project promoting a deeper and more integrated understanding of human behavior and human health. This book aims to show what can, and could be, achieved through our interdisciplinary project. One important product is the newly formed three-party collaboration between Pasteur Institut, Kyoto University, and the Research Institute of Economy, Trade and Industry. Covering many different fields, including medicine, epidemiology, anthropology, economics, sociology, demography, geography, and policy, researchers in these institutes, and many others, present their studies on the COVID-19 pandemic. Although based on different methodologies, the studies show the importance of behavioral change and governmental policy in the fight against a huge pandemic. The book explains the unique genome cohort-panel data that the project builds to study social and life scientific aspects of humans.