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Author: Jean Bousquet
Publisher: CRC Press
ISBN: 9780824701765
Category : Medical
Languages : en
Pages : 0
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Book Description
This massive reference thoroughly analyzes the mechanisms implicated in the pathophysiology of asthma, such as T helper lymphocyte subsets, and the consequences of various extrinsic and intrinsic factors, and IgE receptor expression-reviewing current concepts in immunotherapeutic approaches for the treatment of this and other allergic diseases. Investigates the only category of treatment showing the potential to affect the natural course of allergic diseases and prevent the onset of asthma. Written by more than 80 internationally renowned pulmonary experts, allergic disease specialists, and basic researchers, Immunotherapy in Asthma discusses the efficacy of new medications examines the role of metachromatic cells, lymphocytes, macrophages, and other cell types present in bronchial biopsies presents basic topics such as the functional and phenotypic properties of Th1 and Th2 cells and their role in allergic disease and the regulation of IgE-mediated inflammatory responses addresses the deleterious effects of smoking and passive exposure to cigarette smoke in children and adults assesses differences and similarities between intrinsic and antigen-induced asthma describes the effects of immunogenic peptides on the cytokine production profile of allergen-specific CD4+ T cells explains the different clinical aspects of allergic responses, such as bronchial hyperreactivity and eosinophilic inflammation of the airways reviews the genetic basis of allergy, as well as risk factors for asthma explores oral, sublingual, local nasal, and local bronchial routes for noninjective immunotherapies evaluates various agents with modulatory effects on normal and pathogenic immune responses focuses on strategies for the prevention of childhood asthma and more! Containing over 3000 references, drawings, and tables, Immunotherapy in Asthma is an indispensable resource for pulmonologists, immunologists, allergists, and medical school students in these disciplines.
Author: Jean Bousquet
Publisher: CRC Press
ISBN: 9780824701765
Category : Medical
Languages : en
Pages : 0
Get Book Here
Book Description
This massive reference thoroughly analyzes the mechanisms implicated in the pathophysiology of asthma, such as T helper lymphocyte subsets, and the consequences of various extrinsic and intrinsic factors, and IgE receptor expression-reviewing current concepts in immunotherapeutic approaches for the treatment of this and other allergic diseases. Investigates the only category of treatment showing the potential to affect the natural course of allergic diseases and prevent the onset of asthma. Written by more than 80 internationally renowned pulmonary experts, allergic disease specialists, and basic researchers, Immunotherapy in Asthma discusses the efficacy of new medications examines the role of metachromatic cells, lymphocytes, macrophages, and other cell types present in bronchial biopsies presents basic topics such as the functional and phenotypic properties of Th1 and Th2 cells and their role in allergic disease and the regulation of IgE-mediated inflammatory responses addresses the deleterious effects of smoking and passive exposure to cigarette smoke in children and adults assesses differences and similarities between intrinsic and antigen-induced asthma describes the effects of immunogenic peptides on the cytokine production profile of allergen-specific CD4+ T cells explains the different clinical aspects of allergic responses, such as bronchial hyperreactivity and eosinophilic inflammation of the airways reviews the genetic basis of allergy, as well as risk factors for asthma explores oral, sublingual, local nasal, and local bronchial routes for noninjective immunotherapies evaluates various agents with modulatory effects on normal and pathogenic immune responses focuses on strategies for the prevention of childhood asthma and more! Containing over 3000 references, drawings, and tables, Immunotherapy in Asthma is an indispensable resource for pulmonologists, immunologists, allergists, and medical school students in these disciplines.
Author: Linda S. Cox
Publisher: Elsevier Health Sciences
ISBN: 0323544282
Category : Medical
Languages : en
Pages : 402
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Book Description
Get a quick, expert overview of the use of current and novel immunotherapies for use in the management and treatment of allergic reactions and diseases. This concise resource by Dr. Linda Cox covers the full range of allergic disease, including aeroallergens, asthma, food allergies, atopic dermatitis, and stinging insects. With essential coverage of allergen immunotherapies in addition to key topics on emerging allergen-associated immunomodulators, this succinct, comprehensive reference consolidates today’s available information on this timely topic into a single convenient resource. Discusses timely topics such as food tolerance, allergy, and allergen unresponsiveness; biologics for COPD and pediatric asthma; and adherence and pharmacoeconomics. Summarizes practical guidelines and recommendations for use of immunotherapies in clinical practice. Provides insight into the background and history of immunotherapies as a treatment for allergic disease. Includes developments on the horizon, including alternative immunotherapy routes and modified allergens.
Author: A.B. Singh
Publisher: CRC Press
ISBN: 1351800345
Category : Medical
Languages : en
Pages : 311
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Book Description
Allergy and Allergen Immunotherapy: New Mechanisms and Strategies is a valuable and comprehensive book that covers allergy and causative allergens and provides diagnostic and therapeutic aspects as well. With chapters from internationally recognized experts in the field, the book provides a balanced approach to enumerating pollen allergens as well as allergy diagnosis and therapeutic management and safety assessment of genetically engineered food allergens. The book features a special section on allergic diseases and allergens from tropical countries, including such countries such as India, Sri Lanka, Iran, and South Korea, giving the book a global appeal. The book is broken in the following sections: Epidemiology, Pathophysiology, and Diagnosis of Allergy Aerobiology and Allergic Diseases Pollen Allergy in the Tropics and Temperate Regions Allergy in Children Food Allergy Evaluation Allergen Immunotherapy and Anti IgE The book deals not only on basics of allergy and allergen immunotherapy but also discusses indoor environments and safety considerations of genetically modified food allergens. The first of its kind volume from the Indian subcontinent that caters to the needs of clinicians, aerobiologists, environmentalists, and regulatory agencies as well, the volume will be of immense interest for clinicians and patients of allergy as well as diagnostic and therapeutic management of allergy in tropics.
Author: Jean Bousquet
Publisher: CRC Press
ISBN: 9780824701765
Category : Medical
Languages : en
Pages : 0
Get Book Here
Book Description
This massive reference thoroughly analyzes the mechanisms implicated in the pathophysiology of asthma, such as T helper lymphocyte subsets, and the consequences of various extrinsic and intrinsic factors, and IgE receptor expression-reviewing current concepts in immunotherapeutic approaches for the treatment of this and other allergic diseases. Investigates the only category of treatment showing the potential to affect the natural course of allergic diseases and prevent the onset of asthma. Written by more than 80 internationally renowned pulmonary experts, allergic disease specialists, and basic researchers, Immunotherapy in Asthma discusses the efficacy of new medications examines the role of metachromatic cells, lymphocytes, macrophages, and other cell types present in bronchial biopsies presents basic topics such as the functional and phenotypic properties of Th1 and Th2 cells and their role in allergic disease and the regulation of IgE-mediated inflammatory responses addresses the deleterious effects of smoking and passive exposure to cigarette smoke in children and adults assesses differences and similarities between intrinsic and antigen-induced asthma describes the effects of immunogenic peptides on the cytokine production profile of allergen-specific CD4+ T cells explains the different clinical aspects of allergic responses, such as bronchial hyperreactivity and eosinophilic inflammation of the airways reviews the genetic basis of allergy, as well as risk factors for asthma explores oral, sublingual, local nasal, and local bronchial routes for noninjective immunotherapies evaluates various agents with modulatory effects on normal and pathogenic immune responses focuses on strategies for the prevention of childhood asthma and more! Containing over 3000 references, drawings, and tables, Immunotherapy in Asthma is an indispensable resource for pulmonologists, immunologists, allergists, and medical school students in these disciplines.
Author: Michael J. Parnham
Publisher: Springer Nature
ISBN: 3030108112
Category : Medical
Languages : en
Pages : 888
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Book Description
Principles of Immunopharmacology provides a unique source of essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals. The 4th edition of this internationally recognized textbook has been revised to include recent developments, but continues the established format, dealing with four related fields in a single volume, thus obviating the need to refer to several different textbooks. The first section of the book, providing a basic introduction to immunology and its relevance for human disease, has been updated to accommodate new immunological concepts, particularly the role of epigenetics and the latest understanding of cancer immunology. The second section on immunodiagnostics offers a topical description of widely used molecular techniques and a new chapter on imaging techniques. This is followed by a systematic coverage of drugs affecting the immune system, including natural products. This third section contains 15 updated chapters, covering classical immunopharmacological topics such as anti-asthmatic, anti-rheumatic and immunosuppressive drugs, but also deals with antibiotics, plant-derived and dietary agents, with new chapters on monoclonal antibodies, immunotherapy in sepsis and infection, drugs for soft-tissue autoimmunity and cell therapy. The book concludes with a chapter on immunotoxicology and drug safety tests. Aids to the reader include a two-column format, glossaries of technical terms and appendix reference tables. The emphasis on illustrations is maintained from the first three editions. The book is a valuable single reference for undergraduate and graduate medical and biomedical students, postgraduate chemistry and pharmacy students, researchers in chemistry, biochemistry and the pharmaceutical industry and researchers lacking basic immunological knowledge, who want to understand the actions of drugs on the immune system.
Author: Immunotherapy in Allergic Asthma Consensus Conference (2000, New York, NY)
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Arnaldo Cantani
Publisher: Springer Science & Business Media
ISBN: 3540333959
Category : Medical
Languages : en
Pages : 1634
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Book Description
Easy to understand and easy to use, this essential book reflects the rapid progress in one of the most intriguing fields of medicine. It offers state-of-the-art information on basic immunology, fetal-neonatal immunology, and many more fascinating areas.
Author: Richard F. Lockey
Publisher: CRC Press
ISBN: 1842145738
Category : Medical
Languages : en
Pages : 548
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Book Description
This fifth edition of the bestselling Allergens and Allergen Immunotherapy is now completely updated and revised to include subcutaneous, sublingual, and oral immunomodulator treatments of allergic disease. The redesigned book continues to provide comprehensive coverage of all types of allergens and allergen vaccines, giving clinicians the essential information they need to accurately make a diagnosis and offer the best possible treatments. The fifth edition contains many new and revised chapters—particularly in the fields of skin testing—and extensive updates to the sublingual and oral immunotherapy chapters. Key Features: Comprehensive – covers a vast range of allergens and allergen immunotherapies, providing all the necessary information in one volume Synoptic – supplies the essential information using figures and tables for instant access Up-to-date – includes the very latest information on subcutaneous, sublingual and oral allergen immunotherapies to offer the best possible treatments Reliable – provides basic information that all clinicians need to know about cross-reactivity among allergens and how it influences diagnosis and treatment, as well as the key information necessary to carry out any form of immunotherapy in a safe and effective manner Supplemental forms – contains template forms that can be used by the clinician in daily practice The fifth edition of this classic text continues to be an essential touchstone for any practitioner who conducts skin tests and prescribes subcutaneous, sublingual, and oral immunotherapies.
Author: Massoud Mahmoudi
Publisher: Springer
ISBN: 3319308351
Category : Medical
Languages : en
Pages : 682
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Book Description
This highly practical, easy-to-read, fully updated and expanded resource offers a wide range of targeted guidelines and insights in allergy medicine. Written by a leading allergy clinician -- along with a renowned group of nationally recognized expert contributors in allergy and immunology, pulmonary, and infectious diseases -- this title is a proven resource for front-line general practitioners, especially primary care physicians. The most clinically relevant information is provided on the pathophysiology, diagnosis, treatment, and prevention of all major allergic disorders. Each chapter has a section on “Evidence-Based Medicine” that introduces one to two recent research publications on the subject, and several chapters have been written by new authors. Covering the entire scope of adult and pediatric allergy and asthma and organized by specific organ which guides the reader to diagnostic and therapeutic solutions quickly and easily, the book offers a wealth of outstanding illustrations, key concepts, management protocols, and updated references. An invaluable contribution to the field, Allergy and Asthma: Practical Diagnosis and Management, 2nd Edition will be of immense value not only to primary care physicians, but also to fellows in training, residents, nurses, nurse practitioners, and medical and allied health students.
Author: U. S. Department of Health and Human Services
Publisher: Createspace Independent Pub
ISBN: 9781489521620
Category : Medical
Languages : en
Pages : 494
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Book Description
Allergic rhinitis is a widespread clinical problem, estimated to affect 20 to 40 percent of the population in the U.S. Inhalant allergens, such as plant pollens, characteristically cause seasonal rhinoconjunctivitis and/or asthma; whereas, cat dander, cockroaches, or dust mite allergens may induce symptoms year-round, and are associated with perennial rhinitis and/or asthma. The prevalence of asthma in the U.S. is approximately 9 percent, and approximately 62 percent of individuals with asthma show evidence of also having atopy (i.e., one or more positive-specific IgE levels). The medical management of patients with allergic rhinitis and asthma includes allergen avoidance, pharmacotherapy, and immunotherapy. Allergen-specific immunotherapy (SIT) is typically recommended for patients whose allergic rhinoconjunctivitis and asthma symptoms cannot be controlled by medication and environmental controls, for patients who cannot tolerate medications, or for patients who do not comply with chronic medication regimens. Currently, two forms of specific immunotherapy are used clinically in the U.S. The U.S. Food and Drug Administration (FDA) has approved the use of allergen extracts for subcutaneous administration (subcutaneous immunotherapy) for the treatment of seasonal and perennial allergic rhinitis and allergic asthma. In the U.S., a patient with allergies receives subcutaneous injections of an allergen-containing extract, comprised of the relevant allergens to which the patient is sensitive, in increasing doses, in an attempt to suppress or eliminate allergic symptomatology. Considerable interest has also evolved in using sublingual immunotherapy as an alternative to subcutaneous injection immunotherapy. Sublingual immunotherapy involves placement of the allergen under the tongue for local absorption to desensitize the allergic individual over a period of months to years and diminish allergic symptoms. In 1996, an Immunotherapy Task Force, assembled by the World Allergy Organization, cited the emerging clinical data on sublingual immunotherapy, recognized its potential as a viable alternative to subcutaneous therapy, and encouraged continued clinical investigation to characterize optimal techniques. Over the past two decades, sublingual forms of immunotherapy have gained favor in Europe; sublingual tablet immunotherapy has been approved by the European regulatory authorities. In the U.S., there are currently no FDA-approved sublingual forms of immunotherapy. In the absence of FDA-approved sublingual forms of immunotherapy, some researchers and physicians in the U.S. are exploring the off-label use of subcutaneous aqueous allergens for sublingual desensitization. An increasing number of U.S. physicians are employing this alternate desensitization approach in the treatment of allergic respiratory conditions based on European and U.S. studies, and on the European Medicines Agency's approval of certain oral products; however, due to differing standardization of potency in Europe and the United States, doses have been hard to translate between countries. The primary objective of this comparative effectiveness review is to evaluate the efficacy, effectiveness, and safety of SIT (including both subcutaneous and sublingual immunotherapy) that are presently available for use by clinicians and patients in the U.S. We addressed the following Key Questions (KQs): KQ1. What is the evidence for the efficacy and effectiveness of SIT in the treatment of allergic rhinoconjunctivitis and/or asthma? KQ2. What is the evidence for safety of SIT in patients with allergic rhinoconjunctivitis and/or asthma? KQ3. Is the safety and effectiveness of SIT different in distinct subpopulations with allergic rhinoconjunctivitis and/or asthma? Specifically: Children, Adults, Elderly, Pregnant women, Minorities, Inner-city and rural residents, Monosensitized individuals, Patients with severe asthma.
