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Author: Sudhir Gupta
Publisher: Springer Science & Business Media
ISBN: 1468445596
Category : Medical
Languages : en
Pages : 432
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Book Description
During the past 5 years, impressive progress has been made in understanding the etiopathogenesis of expeiimental and clinical diabetes. The rapid progress that has been made in the general field of immunology has made possible new understanding regarding the role of the immune system in the pathogenesis of diabetes. The other two areas in which recent progress has been made in the field of diabetes include genetics and the role of infectious agent(s) in the etiopathogenesis of diabetes. Because of these recent developments, a vast amount of data has been accumulated and published in a number of metabolic, endocrine, immunological, and general medicine journals. The purpose of this book is to consolidate all the available information and present it in its current state. In the present volume, I strive to bring together relevant contributions from leaders in the fields of immunopathology, immunobiology, and genetics. The advancing understanding has in several instances reached the point of clinical applica tion. This volume encompasses the entire scope of modem immunology of diabetes mellitus. This volume has been divided into two major parts, Experimental Diabetes and Clinical Diabetes. In the Experimental part are included chapters dealing with the structure and functions of insulin and the immune response to insulin. Spontaneous and experimentally induced models of type I diabetes mellitus are presented. The role of virus(es) in the etiology of experimental diabetes and the influence of sex on experi mental diabetes are discussed. The transplantation of pancreas and islets is reviewed in detail.
Author: Sudhir Gupta
Publisher: Springer Science & Business Media
ISBN: 1468445596
Category : Medical
Languages : en
Pages : 432
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Book Description
During the past 5 years, impressive progress has been made in understanding the etiopathogenesis of expeiimental and clinical diabetes. The rapid progress that has been made in the general field of immunology has made possible new understanding regarding the role of the immune system in the pathogenesis of diabetes. The other two areas in which recent progress has been made in the field of diabetes include genetics and the role of infectious agent(s) in the etiopathogenesis of diabetes. Because of these recent developments, a vast amount of data has been accumulated and published in a number of metabolic, endocrine, immunological, and general medicine journals. The purpose of this book is to consolidate all the available information and present it in its current state. In the present volume, I strive to bring together relevant contributions from leaders in the fields of immunopathology, immunobiology, and genetics. The advancing understanding has in several instances reached the point of clinical applica tion. This volume encompasses the entire scope of modem immunology of diabetes mellitus. This volume has been divided into two major parts, Experimental Diabetes and Clinical Diabetes. In the Experimental part are included chapters dealing with the structure and functions of insulin and the immune response to insulin. Spontaneous and experimentally induced models of type I diabetes mellitus are presented. The role of virus(es) in the etiology of experimental diabetes and the influence of sex on experi mental diabetes are discussed. The transplantation of pancreas and islets is reviewed in detail.
Author: Thomas Dyrberg
Publisher: Springer Science & Business Media
ISBN: 364275239X
Category : Medical
Languages : en
Pages : 148
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Book Description
Research in diabetes has accelerated in two areas, both of which are being reviewed in CTMI. The first is the use of a variety of animal models; the second is basic research in human investigation, islet cell antigens, and mapping of genes as sociated with susceptibility to disease. Dr. Thomas Dyrberg accepted editorial responsibility for this volume, which covers the first area. A second book, to be published later in the year, is edited by Drs. Brekkeskov and Hansen (CTMI 164, see page VI for contents). Although the contributors to both volumes represent the international scientific community, the editors are from the Hagedorn Research Laboratory in Denmark. Work at this institute and the Steno Memorial Hospital has been dedicated to research in diabetes for decades, and the insti tutions were appointed WHO Collaborating Centres for Re search and Training on the Pathogenesis of Diabetes Mellitus in 1983. It is worth noting that while addressing the hypothesis of the role of class II major histocompatibility glycoproteins in autoimmune diabetes (insulin-dependent diabetes, IDDM) a number of investigators established animal models in which class II molecules were expressed under the control of the rat insulin promoter. While generating interesting information on 100M, the finding of immunologic tolerance in such transgenic mice has attracted the attention of several basic immunologic laboratories for quite different reasons. Thus, we are reminded again of the Pasteur dictum that "chance favors the prepared mind. " Michael B. A. Oldstone, M. D.
Author: George S. Eisenbarth
Publisher: Springer Science & Business Media
ISBN: 9780306478710
Category : Medical
Languages : en
Pages : 364
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Book Description
In the field of immunology, type 1 diabetes has become one of the major areas of investigation with studies that span from characterization of key molecules to trials for the prevention of the disease. Type 1 Diabetes : Molecular, Cellular and Clinical Immunology communicates both the background and the most recent understanding of this disorder, which will almost certainly be central to elucidating the etiology of autoimmunity, and in particular of organ specific autoimmunity. The book covers immunogenetics, immunopathogenesis, epidemiology, disease prediction and clinical application of current knowledge. Both scientists seeking to understand and prevent type 1 diabetes/autoimmunity as well as physicians caring for families with type 1 diabetes will be interested in this book.
Author: Hubert M. Tse
Publisher: Frontiers Media SA
ISBN: 2889459705
Category :
Languages : en
Pages : 188
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Book Description
Author: Immunology of Diabetes Society. International Congress
Publisher: Wiley-Blackwell
ISBN:
Category : Health & Fitness
Languages : en
Pages : 356
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Book Description
This volume an overview of current research in the field of immunology as it relates to diabetes. Topics covered include: autoantibody markers for type 1 diabetes; cellular immune markers for type 1 diabetes; animal models of type 1 diabetes; the pancreas in type 1 diabetes; genetics of type 1 diabetes; the role of toll-like receptors and innate immunity in type 1 diabetes; cell-based therapies for type 1 diabetes; environmental and mechanistic causes of type 1 diabetes; mechanisms of beta-cell death; role of the immune response in type 1 diabetes; and islet transplantation. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member.
Author: Domenico Andreani
Publisher:
ISBN:
Category : Diabetes
Languages : en
Pages : 320
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Book Description
Author: Immunology of Diabetes Society. Meeting
Publisher:
ISBN:
Category : Health & Fitness
Languages : en
Pages : 248
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Book Description
This volume brings together reports from scientists working in the fields of immunology genetics that refer to both human and animal models of diabetes. In addition, developmental and transplantation biologists report on beta cell development and islet transplantation.
Author: Immunology of Diabetes Society. Congress
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 464
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Book Description
The papers included here examine all aspects of diabetes immunology, including studies on the genetics, pathogenesis, prediction, prevention and treatment of the disease. A particular emphasis is given to the human model of the disease as well as to advances in the broader fields of immunology and autoimmunity.
Author: Pratima Tripathi
Publisher: Elsevier
ISBN: 0443131961
Category : Medical
Languages : en
Pages : 444
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Book Description
Biochemical Immunology of Diabetes and Associated Complications offers in-depth coverage of the association of biochemical and immunological aspects of the human body in diabetes. It discusses the suppression and modulation of the immune system and the impact of immunochemicals on the biochemical pathways in diabetes, and associated complications. It enumerates the exigency in knowledge about the immunomodulators as therapeutic targets to cure the syndrome. This book will serve as an important reference for medical practitioners, researchers, medical students, masters and doctoral students of life sciences background. It could also be used as a reference book for science graduates, science teachers and researchers from academia and industry. Presents information on Immunosuppression and Immunomodulation that directly or indirectly affects the biochemistry underlying diabetes Highlights the association of immunological and biochemical aspects in diabetes to gain a better understanding in handling the disease Presents the latest research on inflammatory-mediated responses in the development of diabetes Includes a chapter of Case studies related to the diseases in question
Author: William James Irvine
Publisher:
ISBN: 9780845102107
Category : Diabetes
Languages : en
Pages : 377
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Book Description
