Immunology and Immunopathology of the Liver and Gastrointestinal Tract

Immunology and Immunopathology of the Liver and Gastrointestinal Tract PDF Author: Stephan R. Targan
Publisher: Igaku-Shoin Medical Publishers
ISBN:
Category : Medical
Languages : en
Pages : 680

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Immunology and Immunopathology of the Liver and Gastrointestinal Tract

Immunology and Immunopathology of the Liver and Gastrointestinal Tract PDF Author: Stephan R. Targan
Publisher: Igaku-Shoin Medical Publishers
ISBN:
Category : Medical
Languages : en
Pages : 680

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Immunological Aspects of the Liver and Gastrointestinal Tract

Immunological Aspects of the Liver and Gastrointestinal Tract PDF Author: A. Ferguson
Publisher: Springer Science & Business Media
ISBN: 940116150X
Category : Medical
Languages : en
Pages : 413

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Book Description
We have been privileged to start our academic careers at the begin ning of the decade in which the immunological roles and hypersensitivity diseases of the gastrointestinal tract and liver have been defined. In the early 1960s IgA was reported to be the main secretory immunoglobulin, immunoblasts were shown to home to the intestinal mucosa and certain serum autoantibodies were described in patients with chronic liver disease. Shortly thereafter IgE and Australia antigen were discovered. Parallel advances in clinical investigation, in particular closed biopsy techniques, facilitated correlation of morphological changes with im munological mechanisms in disease of the gastrointestinal tract and liver. Only 10 years later, the concepts of immunity and hypersensitivity are regularly applied to the pathogenesis, diagnosis, treatment and prog nosis of many chronic diseases in these organs. In designing this book we have attempted to integrate theorectical and clinical immunology as they pertain in 1975; our ultimate aim is aptly described by Brachet as quoted by Professor Paronetto (page 319). We would like to think that this review provides a basis for the next major advances in the fields of gastrointestinal and hepatic immunology. As we see it, the outstanding problem in both sites is how to produce protective immunity without hypersensitivity.

Clinical Immunology of the Liver and Gastrointestinal Tract

Clinical Immunology of the Liver and Gastrointestinal Tract PDF Author: David R. Triger
Publisher: Butterworth-Heinemann
ISBN:
Category : Medical
Languages : en
Pages : 260

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Immunology of the Gastrointestinal Tract and Liver

Immunology of the Gastrointestinal Tract and Liver PDF Author: Martin F. Heyworth
Publisher: Lippincott Williams & Wilkins
ISBN:
Category : Medical
Languages : en
Pages : 250

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Gastrointestinal and Hepatic Immunology

Gastrointestinal and Hepatic Immunology PDF Author: Richard Heatley
Publisher: Cambridge University Press
ISBN: 0521445094
Category : Medical
Languages : en
Pages : 412

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Book Description
This 1994 volume summarizes basic scientific advances in the area of the gut immune system and the immune abnormalities relevant to gastrointestinal and liver disease.

Liver and Gastrointestinal Immunology

Liver and Gastrointestinal Immunology PDF Author: Michael P. Manns
Publisher:
ISBN: 9780702021879
Category : Cellular immunity
Languages : en
Pages : 162

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Book Description
This work on liver and gastroenterology covers such topics as the regulation of the mucosal epithelial cell barrier; antigen preservation in the intestinal tract; special features of the intestinal lymphatic system; and the immunopathology of primary biliary cirrhosis.

Immunology of Gastrointestinal and Liver Disease

Immunology of Gastrointestinal and Liver Disease PDF Author: Ralph Wright (M.D.)
Publisher: Hodder Education
ISBN:
Category : Medical
Languages : en
Pages : 148

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Immunological Aspects of Liver Disease

Immunological Aspects of Liver Disease PDF Author: H.C. Thomas
Publisher: Springer Science & Business Media
ISBN: 3642684467
Category : Medical
Languages : en
Pages : 338

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Book Description
Howard C. Thomas In normal subjects the regulatory apparatus of the immune system permits responses to foreign antigens but suppresses those directed to "self' components. Autoimmune disease occurs as a failure ofthis system either as a result of a primary defect in the regulatory apparatus (primary autoimmunization) or because of a change in the antigenicity of the tissues (secondary autoimmunization). Autoaggressive reactions are characterised by the presence of autoantibodies. When these are directed to membrane displayed antigens (Fig. 1) they are probably of importance in the lysis of hepatocytes. Those directed to cytoplasmic antigens may be useful diagnostically but are of unknown pathogenic significance. When no extrinsic aetiological factor can be identified, the process is assumed to be the result of a failure ofthe regulatory system, allowing the spontaneous expansion of a clone of autoreactive lymphocytes. The defect may be generalised or specific to certain groups of self-antigens and thus the autoimmune disease may be either multi- or unisystemic. The recent development of techniques to enumerate and measure the functional activity of the suppressor lymphocytes which control the effector limbs of the immune system has enabled investigators to test whether the various purported autoimmune diseases do have as their basis a generalised defect in immunoregu lation. Assessment of antigen-specific immunoregulatory function is, however, not yet readily available. liver Membrane I Antigen (LIM) I Liver I HLA, A, B, C, Sensitisation to Specific -;::!IIIL. .

Immunological Diseases of Liver and Gut

Immunological Diseases of Liver and Gut PDF Author: M. Lukás
Publisher: Springer Science & Business Media
ISBN: 9780792387923
Category : Medical
Languages : en
Pages : 338

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Book Description
This book is the proceedings of the Falk Symposium No. 135 held in Prague, Czech Republic, on September 12-13, 2003, and is dedicated to the important issue of immunological aspects of diseases of the liver and gut. Without any doubt, immunological pathways are among the most important and universal factors in the pathogenesis of all diseases. Their importance is also constantly increasing, because these principles have been adopted in clinical practice for both diagnostic and therapeutic procedures. Chapters by prominent experts will stimulate new ideas and set the scene for productive discussion on this topic.

Immunology of Gastrointestinal Disease

Immunology of Gastrointestinal Disease PDF Author: T.T. Macdonald
Publisher: Springer Science & Business Media
ISBN: 9401129789
Category : Medical
Languages : en
Pages : 312

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Book Description
Gastrointestinal diseases present a considerable problem in human medicine in terms of both morbidity and mortality. The aim of this book is to cover the different immunological disorders of the gut with special reference to immunopathological and protective mechanisms. It will be of general interest to clinicians, scientists and students concerned with the gastrointestinal tract. Topics covered include: the current status of research into toxin-secreting pathogens, Campylobacter, Giardia and HIV; the immunological features of idiopathic inflammatory gut diseases such as Crohn's disease and intractable diarrhoea; the genesis of the flat mucosa; the iatrogenic diseases of the gut such as graft-versus-host disease and small bowel allografts; the immune mechanisms and lesions in the gut of patients with parasitic nematode infections (very important in the tropics). Basic background on the immune apparatus in the intestine is also discussed, as are the effects of inflammation on intestinal permeability.