Immunogenetic Risk Assessment in Human Disease PDF Download
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Author: Janardan P. Pandey
Publisher: S Karger Ag
ISBN: 9783805562157
Category : Medical
Languages : en
Pages : 0
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Book Description
Recent findings have increased our understanding of HLA and the immunoglobulin allotypes Gm and Km, and their role in the genetic control of immune responsiveness and susceptibility to disease. These significant discoveries, which were presented at the international conference on Immunogenetic Risk Assessment in Human Disease held in Charleston, S.C., in March 1994, are now featured in this special issue. Some of the contributions discuss modern molecular methods for the detection of these polymorphic systems as well as their influence on the predisposition to various human diseases - especially autoimmune and infectious diseases. Other articles review biometrical methods employed to identify genes implicated in human diseases. Furthermore, possible reasons for the evolution of the extensive polymorphism of HLA and Gm systems are given. This fascinating publication on two important gene complexes of the human immune system will be of great value to scientists working in the fields of immunology, and immunogenetics, human genetics, genetic epidemiology, population genetics and physical anthropology.
Author: Janardan P. Pandey
Publisher: S Karger Ag
ISBN: 9783805562157
Category : Medical
Languages : en
Pages : 0
Get Book Here
Book Description
Recent findings have increased our understanding of HLA and the immunoglobulin allotypes Gm and Km, and their role in the genetic control of immune responsiveness and susceptibility to disease. These significant discoveries, which were presented at the international conference on Immunogenetic Risk Assessment in Human Disease held in Charleston, S.C., in March 1994, are now featured in this special issue. Some of the contributions discuss modern molecular methods for the detection of these polymorphic systems as well as their influence on the predisposition to various human diseases - especially autoimmune and infectious diseases. Other articles review biometrical methods employed to identify genes implicated in human diseases. Furthermore, possible reasons for the evolution of the extensive polymorphism of HLA and Gm systems are given. This fascinating publication on two important gene complexes of the human immune system will be of great value to scientists working in the fields of immunology, and immunogenetics, human genetics, genetic epidemiology, population genetics and physical anthropology.
Author: Malcolm J. Simons
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 168
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Book Description
Author: Dennis K. Flaherty
Publisher: Springer Science & Business Media
ISBN: 0306468107
Category : Medical
Languages : en
Pages : 378
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Book Description
This authored book presents basic immunological tenets and mechanisms at the cellular and molecular level while employing the toxicology focus on hazard identification, appropriate assays, dose response, and risk assesment by mathematical models and safety factors. It will be a useful reference to toxicologists because it will incorporate new guidelines that the EPA is bringing out later this year for all chemicals regulated under the Federal Insecticide, Fungicide, and Rodenticide Act and the Toxic Substances Control Act. Regulatory sections in each chapter focus on data from both the US Food and Drug Administration, as well as data applicable to western European Nations.
Author: Muneeb U Rehman
Publisher: Academic Press
ISBN: 0323903355
Category : Medical
Languages : en
Pages : 412
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Book Description
A Molecular Approach to Immunogenetics, Immunogenetics: A Molecular and Clinical Overview, Volume One provides readers with an exclusive, updated overview on the scientific knowledge, achievements and findings in the field of immunogenetics. The book presents readily available, updated information on the molecular and clinical aspects of immunogenetics, from origin and development to clinical applications and future prospects. The breadth of information goes from basics to developments, clinical applications and future prospects. The book's most attractive attribute is its academic and clinical amalgamation that covers both the theoretical and practical aspects of immunogenetics. An additional feature of the book is a special chapter on viral genetics that covers COVID-19. Above all, the book contains chapters that discuss immunogenetics in relation to pharmaco-genomics and immune-toxicology. - Contains exclusive information about research on immunogenetics from around the globe - Includes minute and recent details that will be the prerequisite requirement for any researcher who wants to work on immunogenetics and its applications - Comes fully-equipped with pictures, illustrations and tables that deliver information in a meticulous manner
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309220424
Category : Science
Languages : en
Pages : 200
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Book Description
For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model in the past, most current biomedical research use of chimpanzees is not necessary, though noted that it is impossible to predict whether research on emerging or new diseases may necessitate chimpanzees in the future.
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309169887
Category : Medical
Languages : en
Pages : 304
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Book Description
By two years of age, healthy infants in the United States can receive up to 20 vaccinations to protect against 11 diseases. Although most people know that vaccines effectively protect against serious infectious diseases, approximately one-quarter of parents in a recent survey believe that infants get more vaccines than are good for them, and that too many immunizations could overwhelm an infant's immune system. The Immunization Safety Review Committee reviewed the evidence regarding the hypothesis that multiple immunizations increase the risk for immune dysfunction. Specifically, the committee looked at evidence of potential biological mechanisms and at epidemiological evidence for or against causality related to risk for infections, the autoimmune disease type 1 diabetes, and allergic disorders.
Author:
Publisher: Springer
ISBN: 9781617798436
Category :
Languages : en
Pages : 708
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Book Description
Author: Centers for Disease Control and Prevention CDC
Publisher: Oxford University Press
ISBN: 0190628634
Category : Medical
Languages : en
Pages : 705
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Book Description
THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.
Author: Kenneth Murphy
Publisher: Garland Science
ISBN: 9780815344575
Category : Medical
Languages : en
Pages :
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Book Description
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author: Alexander Choukèr
Publisher: Springer Nature
ISBN: 3030169960
Category : Medical
Languages : en
Pages : 756
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Book Description
This book explains how stress – either psychological or physical – can activate and/or paralyse human innate or adaptive immunity. Adequate immunity is crucial for maintaining health, both on Earth and in space. During space flight, human physiology is specifically challenged by complex environmental stressors, which are most pronounced during lunar or interplanetary missions. Adopting an interdisciplinary approach, the book identifies the impact of these stressors – the space exposome – on immunity as a result of (dys-)functions of specific cells, organs and organ networks. These conditions (e.g. gravitation changes, radiation, isolation/confinement) affect immunity, but at the same time provide insights that may help to prevent, diagnose and address immune-related health alterations. Written by experts from academia, space agencies and industry, the book is a valuable resource for professionals, researchers and students in the field of medicine, biology and technology. The chapters “The Impact of Everyday Stressors on the Immune System and Health”, “Stress and Radiation Responsiveness” and “Assessment of Radiosensitivity and Biomonitoring of Exposure to Space adiation” are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
