Author: Claudia Kuntner-Hannes
Publisher: Springer
ISBN: 3030029735
Category : Medical
Languages : en
Pages : 212
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Book Description
This book provides an accessible and comprehensive overview of the state of the art in multimodal, multiparametric preclinical imaging, covering all the modalities used in preclinical research. The role of different combinations of PET, CT, MR, optical, and optoacoustic imaging methods is examined and explained for a range of applications, from research in oncology, neurology, and cardiology to drug development. Examples of animal studies are highlighted in which multimodal imaging has been pivotal in delivering otherwise unobtainable information. Hardware and software image registration methods and animal-specific factors are also discussed. The readily understandable text is enhanced by numerous informative illustrations that help the reader to appreciate the similarities to, but also the differences from, clinical applications. Image Fusion in Preclinical Applications will be of interest to all who wish to learn more about the use of multimodal/multiparametric imaging as a tool for in vivo investigations in preclinical medical and pharmaceutical research.
Author: Chun Yin
Publisher: Springer Nature
ISBN: 9819982162
Category : Technology & Engineering
Languages : en
Pages : 280
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Book Description
The book focuses on infrared thermographic NDT systems and approaches. Both principles and engineering practice are covered, with more emphasis on the engineering practice of spacecraft damage detection and analysis. This is achieved by providing an in-depth study of several major topics such as infrared feature extraction, damage reconstruction, reconstructed image fusion, reconstructed image stitching, reconstructed image segmentation, defect positioning, defect edge detection and quantitative calculation. A number of application cases are discussed in detail, including impact damage to single-layer and multi-layer protective configurations, simple impact damage, and complex multi-type impact damage. The comprehensive and systematic treatment of practical problems in infrared detection and spacecraft damage identification is one of the main features of this book, which is particularly suitable for those interested in learning practical solutions in infrared detection technology. This book can benefit researchers, engineers, and graduate students in the fields of aerospace design and manufacturing, spacecraft environmental engineering, and non-destructive testing technology, etc.
Author: Srivastava, Rajeev
Publisher: IGI Global
ISBN: 1466645598
Category : Computers
Languages : en
Pages : 451
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Book Description
Similar to the way in which computer vision and computer graphics act as the dual fields that connect image processing in modern computer science, the field of image processing can be considered a crucial middle road between the vision and graphics fields. Research Developments in Computer Vision and Image Processing: Methodologies and Applications brings together various research methodologies and trends in emerging areas of application of computer vision and image processing. This book is useful for students, researchers, scientists, and engineers interested in the research developments of this rapidly growing field.
Author: Ardeshir R. Rastinehad
Publisher: Springer Nature
ISBN: 3030735656
Category : Medical
Languages : en
Pages : 567
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Book Description
This updated text provides a concise yet comprehensive and state-of-the-art review of evolving techniques in the new and exciting subspecialty of interventional urology. Significant advances in imaging technologies, diagnostic tools, fusion navigation, and minimally invasive image-guided therapies such as focal ablative therapies have expanded the interventional urologists’ clinical toolkit over the past decade. Organized by organ system with subtopics covering imaging technologies, interventional techniques, recipes for successful practice, pitfalls to shorten the learning curves for new technologies, and clinical outcomes for the vast variety of interventional urologic procedures, this second edition includes many more medical images as well as helpful graphics and reference illustrations. The second edition of Interventional Urology serves as a valuable resource for clinicians, interventional urologists, interventional radiologists, interventional oncologists, urologic oncologists, as well as scientists, researchers, students, and residents with an interest in interventional urology.
Author: Stefan R. Schmidt
Publisher: John Wiley & Sons
ISBN: 1118354583
Category : Medical
Languages : en
Pages : 995
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Book Description
The state of the art in biopharmaceutical FUSION PROTEIN DESIGN Fusion proteins belong to the most lucrative biotech drugs—with Enbrel® being one of the best-selling biologics worldwide. Enbrel® represents a milestone of modern therapies just as Humulin®, the first therapeutic recombinant protein for human use, approved by the FDA in 1982 and Orthoclone® the first monoclonal antibody reaching the market in 1986. These first generation molecules were soon followed by a plethora of recombinant copies of natural human proteins, and in 1998, the first de novo designed fusion protein was launched. Fusion Protein Technologies for Biopharmaceuticals examines the state of the art in developing fusion proteins for biopharmaceuticals, shedding light on the immense potential inherent in fusion protein design and functionality. A wide pantheon of international scientists and researchers deliver a comprehensive and complete overview of therapeutic fusion proteins, combining the success stories of marketed drugs with the dynamic preclinical and clinical research into novel drugs designed for as yet unmet medical needs. The book covers the major types of fusion proteins—receptor-traps, immunotoxins, Fc-fusions and peptibodies—while also detailing the approaches for developing, delivering, and improving the stability of fusion proteins. The main body of the book contains three large sections that address issues key to this specialty: strategies for extending the plasma half life, the design of toxic proteins, and utilizing fusion proteins for ultra specific targeting. The book concludes with novel concepts in this field, including examples of highly relevant multifunctional antibodies. Detailing the innovative science, commercial realities, and brilliant potential of fusion protein therapeutics, Fusion Protein Technologies for Biopharmaceuticals is a must for pharmaceutical scientists, biochemists, medicinal chemists, molecular biologists, pharmacologists, and genetic engineers interested in determining the shape of innovation in the world of biopharmaceuticals.
Author: Fred S. Azar
Publisher: Artech House
ISBN: 1596933089
Category : Medical
Languages : en
Pages : 431
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Book Description
Supported with 119 illustrations, this milestone work discusses key optical imaging techniques in self-contained chapters; describes the integration of optical imaging techniques with other modalities like MRI, X-ray imaging, and PET imaging; provides a software platform for multimodal integration; presents cutting-edge computational and data processing techniques that ensure rapid, cost-effective, and precise quantification and characterization of the clinical data; covers advances in photodynamic therapy and molecular imaging, and reviews key clinical studies in optical imaging along with regulatory and business issues.
Author: Yves Lemoigne
Publisher: Springer Science & Business Media
ISBN: 1402056532
Category : Science
Languages : en
Pages : 403
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Book Description
This book introduces the fundamental aspects of digital imaging and covers four main themes: ultrasound techniques and imaging applications, magnetic resonance and MPJ in hospital, digital imaging with X-rays, and emission tomography (PET and SPECT). Each topic is developed by analyzing the underlying physics principles and their implementation, quality and safety aspects, clinical performance, and recent advancements in the field.
Author: Petr Skoda
Publisher: Elsevier
ISBN: 0128191554
Category : Computers
Languages : en
Pages : 474
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Book Description
Knowledge Discovery in Big Data from Astronomy and Earth Observation: Astrogeoinformatics bridges the gap between astronomy and geoscience in the context of applications, techniques and key principles of big data. Machine learning and parallel computing are increasingly becoming cross-disciplinary as the phenomena of Big Data is becoming common place. This book provides insight into the common workflows and data science tools used for big data in astronomy and geoscience. After establishing similarity in data gathering, pre-processing and handling, the data science aspects are illustrated in the context of both fields. Software, hardware and algorithms of big data are addressed. Finally, the book offers insight into the emerging science which combines data and expertise from both fields in studying the effect of cosmos on the earth and its inhabitants. - Addresses both astronomy and geosciences in parallel, from a big data perspective - Includes introductory information, key principles, applications and the latest techniques - Well-supported by computing and information science-oriented chapters to introduce the necessary knowledge in these fields
Author: Wolfhard Semmler
Publisher: Springer Science & Business Media
ISBN: 3540727183
Category : Medical
Languages : en
Pages : 298
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Book Description
The aim of this textbook of molecular imaging is to provide an up to date review of this rapidly growing field and to discuss basic methodological aspects necessary for the interpretation of experimental and clinical results. Emphasis is placed on the interplay of imaging technology and probe development, since the physical properties of the imaging approach need to be closely linked with the biologic application of the probe (i.e. nanoparticles and microbubbles). Various chemical strategies are discussed and related to the biologic applications. Reporter-gene imaging is being addressed not only in experimental protocols, but also first clinical applications are discussed. Finally, strategies of imaging to characterize apoptosis and angiogenesis are described and discussed in the context of possible clinical translation.
Author: George C. Kagadis
Publisher: CRC Press
ISBN: 1315362791
Category : Medical
Languages : en
Pages : 624
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Book Description
The use of small animal models in basic and preclinical sciences constitutes an integral part of testing new pharmaceutical agents prior to their application in clinical practice. New imaging and therapeutic approaches need to be tested and validated first in animals before application to humans. Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Applications collects the latest information about various imaging and therapeutic technologies used in preclinical research into a single source. Useful to established researchers as well as newcomers to the field, this handbook shows readers how to exploit and integrate these imaging and treatment modalities and techniques into their own research. The book first presents introductory material on small animal imaging, therapy, and research ethics. It next covers ionizing radiation and nonionizing radiation methods in small animal imaging, hybrid imaging, and imaging agents. The book then addresses therapeutic research platforms and image quantification, explaining how to ensure accurate measurements of high-quality data. It concludes with an overview of many small animal imaging and therapy applications that demonstrate the strength of the techniques in biomedical fields.
