Identifying and Estimating the Genetic Impact of Chemical Mutagens PDF Download
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Author: National Research Council (U.S.). Committee on Chemical Environmental Mutagens
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 312
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Book Description
And conclusions; Introduction; A primer on genetics, mutation, mutagens, and the implications of mutagenesis; Metabolism and pharmacologic disposition of mutagens and promutagens; The nature of test systems; Strategies for risk assessment: the choice and use of test systems to estimative human germinal mututation; Strategies for risk assessment: relation between mutation rate and human welfare; Testing and monitoring human populations; A mutagen assessment program; Some additional issues and research suggestions.
Author: National Research Council (U.S.). Committee on Chemical Environmental Mutagens
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 312
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Book Description
And conclusions; Introduction; A primer on genetics, mutation, mutagens, and the implications of mutagenesis; Metabolism and pharmacologic disposition of mutagens and promutagens; The nature of test systems; Strategies for risk assessment: the choice and use of test systems to estimative human germinal mututation; Strategies for risk assessment: relation between mutation rate and human welfare; Testing and monitoring human populations; A mutagen assessment program; Some additional issues and research suggestions.
Author:
Publisher: National Academies
ISBN:
Category : Medical
Languages : en
Pages : 332
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Book Description
And conclusions; Introduction; A primer on genetics, mutation, mutagens, and the implications of mutagenesis; Metabolism and pharmacologic disposition of mutagens and promutagens; The nature of test systems; Strategies for risk assessment: the choice and use of test systems to estimative human germinal mututation; Strategies for risk assessment: relation between mutation rate and human welfare; Testing and monitoring human populations; A mutagen assessment program; Some additional issues and research suggestions.
Author: Joanna Jankowicz-Cieslak
Publisher: Springer
ISBN: 3319450212
Category : Science
Languages : en
Pages : 343
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Book Description
This book is open access under a CC BY-NC 2.5 license. This book offers 19 detailed protocols on the use of induced mutations in crop breeding and functional genomics studies, which cover topics including chemical and physical mutagenesis, phenotypic screening methods, traditional TILLING and TILLING by sequencing, doubled haploidy, targeted genome editing, and low-cost methods for the molecular characterization of mutant plants that are suitable for laboratories in developing countries. The collection of protocols equips users with the techniques they need in order to start a program on mutation breeding or functional genomics using both forward and reverse-genetic approaches. Methods are provided for seed and vegetatively propagated crops (e.g. banana, barley, cassava, jatropha, rice) and can be adapted for use in other species.
Author: Ernest H.Y. Chu
Publisher: Springer Science & Business Media
ISBN: 1461323991
Category : Science
Languages : en
Pages : 852
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Book Description
During the early 1930s, when I was a graduate student and later a post-doctoral researcher at the National Research Council for the University of Wisconsin at Madison, we had the opportunity to get acquainted with many graduate students from China who were sent to the University for training in modern basic sciences as well as social sciences. The University of Wisconsin continues to graduate a large number of Chinese students. Economic conditions in the 1930s were very precarious for the United States and other parts of the world. Many of us students grew closer together because we were living on similarly tight budgets. As a matter of fact, we subleased a part of our apartment in Madison to some Chinese graduate students. This was a very nice opportunity for us to learn about the scientific and cultural back ground of our Chinese friends. Many of them came from the interior of China and had had very little opportunity to become acquainted with people from a western culture. Living with these students was a very pleasant and educational experience which gave us a good pic ture of the cultural life and educational system of China at that time--an intimate picture that one normally would not see without travelling in that country.
Author:
Publisher:
ISBN:
Category : Delegated legislation
Languages : en
Pages : 2204
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Book Description
Author: John J. Cohrssen
Publisher: DIANE Publishing
ISBN: 0788149989
Category :
Languages : en
Pages : 420
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Book Description
Designed for consumers of risk information, this book offers a balance between the technical and nontechnical literature. The discipline of risk analysis has developed into an organized body of knowledge and methods only within the past 20 years. The passage of federal laws to protect public health and the environment has generated rapid growth in risk analysis in numerous fields. Statements of risk need to be understood to be useful to the public and environmental managers. This guidebook provides a tool for understanding risk analysis. Chapters: overview of risk analysis; hazard identification; risk assessment; and risk communication.
Author: B.A. Ponder
Publisher: Springer Science & Business Media
ISBN: 9401106770
Category : Medical
Languages : en
Pages : 222
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Book Description
It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.
Author: Harry Harris
Publisher: Springer Science & Business Media
ISBN: 1461594006
Category : Medical
Languages : en
Pages : 407
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Book Description
From reviews of previous volumes in the series: 'Extremely valuable ... thoroughly recommended.'-Annals of Human Genetics 'The most lucid and stimulating discussions of the topic to be found anywhere.'-American Scientist.
Author: H.C. Grice
Publisher: Springer Science & Business Media
ISBN: 3642493718
Category : Medical
Languages : en
Pages : 200
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Book Description
The International Life Sciences Institute (lLSI) is a scientific foundation wh ich addresses critical health and safety issues of national and international concern. ILSI promotes international cooperation by pro viding the mechanism for scientists from government, industry and universities to work together on cooperative programs to generate and disseminate scientific data. The members and trustees of the Institute believe that questions regarding health and safety are best resolved when scientists can ex amine and discuss issues, as an independent body, se~arate from the political pressures of individual countries and the economic concerns of individual companies. Frequently, meaningful assessment of the risk of a test substance is hindered by the inherent inconsistencies in the system. The development and refinement of methods and systems to evaluate the safety of chemicals have evolved in a rapid and largely unplanned fashion. Attempts to improve the system have largely been directed toward broad general concerns, with little attention being given to specific problems or issues. A failure to resolve these problems has frequently resulted in increased testing costs and complications in the assessment and extrapolation of the results. Publicity surrounding toxicologic issues has created chronic public apprehension about the ability of science and government to deal effectively with these problems. In response to these difficulties, ILSI has assembled highly qualified and renowned scientists from research institutes, universities, government and industry, with relevant scientific knowledge and expertise regarding the issues that complicate risk assessment procedures.
Author: Albert P. Li
Publisher: CRC Press
ISBN: 9780849388156
Category : Medical
Languages : en
Pages : 508
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Book Description
Genetic Toxicology is a comprehensive book covering the historical perspective of genetic toxicology; basic mechanisms of mutations and chromosomal effects; health consequences of genetic damage, including cancer and inheritable mutations; properties of physical, chemical, and biological mutagens; risk assessment of human exposure to genotoxicants; and the current position of some government regulatory agencies in the United States on the issues of genetic toxicology. The book will be a useful reference for students and researchers in toxicology, genetics, cancer biology, and medicine who are interested in the basic and applied principles of genetic toxicology. It will also benefit industrial toxicologists, products registration specialists, and government regulatory specialists with responsibility for the safety evaluation of industrial and environmental agents.
