Author: Olivier Girard
Publisher: Taylor & Francis
ISBN: 1040118984
Category : Medical
Languages : en
Pages : 358
Book Description
While severe hypoxia has detrimental health consequences, the controlled application of hypoxia can be protective and holds great promise as a performance-enhancing and therapeutic intervention. Hypoxia Conditioning in Health, Exercise and Sport: Principles, Mechanisms and Applications delivers an understanding of systemic and molecular mechanisms involved in hypoxia adaptations and examines the most promising forms of hypoxia conditioning with a view to create performance-enhancing strategies for athletes, as well as an offering an examination on clinical applications for numerous pathologies. This cutting-edge book examines how positive physiological adaptations not only acutely enhance tolerance to hypoxia but can also induce sustained health benefits. This has enabled the development and refinement of approaches utilizing hypoxia, strategies also termed hypoxia conditioning, to improve health and performance outcomes. By linking research with recommendations for real-world situations, this volume will serve as an invaluable resource for students, academics, exercise science professionals and sports medicine specialists, especially those in environmental physiology and coaching subjects.
Hypoxia Conditioning in Health, Exercise and Sport
Author: Olivier Girard
Publisher: Taylor & Francis
ISBN: 1040118984
Category : Medical
Languages : en
Pages : 358
Book Description
While severe hypoxia has detrimental health consequences, the controlled application of hypoxia can be protective and holds great promise as a performance-enhancing and therapeutic intervention. Hypoxia Conditioning in Health, Exercise and Sport: Principles, Mechanisms and Applications delivers an understanding of systemic and molecular mechanisms involved in hypoxia adaptations and examines the most promising forms of hypoxia conditioning with a view to create performance-enhancing strategies for athletes, as well as an offering an examination on clinical applications for numerous pathologies. This cutting-edge book examines how positive physiological adaptations not only acutely enhance tolerance to hypoxia but can also induce sustained health benefits. This has enabled the development and refinement of approaches utilizing hypoxia, strategies also termed hypoxia conditioning, to improve health and performance outcomes. By linking research with recommendations for real-world situations, this volume will serve as an invaluable resource for students, academics, exercise science professionals and sports medicine specialists, especially those in environmental physiology and coaching subjects.
Publisher: Taylor & Francis
ISBN: 1040118984
Category : Medical
Languages : en
Pages : 358
Book Description
While severe hypoxia has detrimental health consequences, the controlled application of hypoxia can be protective and holds great promise as a performance-enhancing and therapeutic intervention. Hypoxia Conditioning in Health, Exercise and Sport: Principles, Mechanisms and Applications delivers an understanding of systemic and molecular mechanisms involved in hypoxia adaptations and examines the most promising forms of hypoxia conditioning with a view to create performance-enhancing strategies for athletes, as well as an offering an examination on clinical applications for numerous pathologies. This cutting-edge book examines how positive physiological adaptations not only acutely enhance tolerance to hypoxia but can also induce sustained health benefits. This has enabled the development and refinement of approaches utilizing hypoxia, strategies also termed hypoxia conditioning, to improve health and performance outcomes. By linking research with recommendations for real-world situations, this volume will serve as an invaluable resource for students, academics, exercise science professionals and sports medicine specialists, especially those in environmental physiology and coaching subjects.
Exercise Under Hypoxia as an Effective Intervention for Athletic Performance and Health Promotion
Author: Hun-Young Park
Publisher:
ISBN: 9781636481708
Category :
Languages : en
Pages : 322
Book Description
This book contains original and review article performed in our lab (Physical Activity and Performance Institude, Konkuk University, Korea). This content explains the effectiveness of various exercise training and intervention under hypoxia for enhancing athletic performance and various cardiometabolic health including obesity. By reading this textbook, it is believed that many readers will better understand the effectiveness of hypoxic training and hypoxic therapy.
Publisher:
ISBN: 9781636481708
Category :
Languages : en
Pages : 322
Book Description
This book contains original and review article performed in our lab (Physical Activity and Performance Institude, Konkuk University, Korea). This content explains the effectiveness of various exercise training and intervention under hypoxia for enhancing athletic performance and various cardiometabolic health including obesity. By reading this textbook, it is believed that many readers will better understand the effectiveness of hypoxic training and hypoxic therapy.
Intermittent Hypoxia and Human Diseases
Author: Lei Xi
Publisher: Springer Science & Business Media
ISBN: 1447129067
Category : Medical
Languages : en
Pages : 310
Book Description
Intermittent hypoxia can cause significant structural and functional impact on the systemic, organic, cellular and molecular processes of human physiology and pathophysiology. This book focuses on the most updated scientific understanding of the adaptive (beneficial) and maladaptive (detrimental) responses to intermittent hypoxia and their potential pathogenetic or prophylactic roles in the development and progression of major human diseases. This is a comprehensive monograph for clinicians, research scientists, academic faculty, postgraduate and medical students, and allied health professionals who are interested in enhancing their up-to-date knowledge of intermittent hypoxia research and its translational applications in preventing and treating major human diseases.
Publisher: Springer Science & Business Media
ISBN: 1447129067
Category : Medical
Languages : en
Pages : 310
Book Description
Intermittent hypoxia can cause significant structural and functional impact on the systemic, organic, cellular and molecular processes of human physiology and pathophysiology. This book focuses on the most updated scientific understanding of the adaptive (beneficial) and maladaptive (detrimental) responses to intermittent hypoxia and their potential pathogenetic or prophylactic roles in the development and progression of major human diseases. This is a comprehensive monograph for clinicians, research scientists, academic faculty, postgraduate and medical students, and allied health professionals who are interested in enhancing their up-to-date knowledge of intermittent hypoxia research and its translational applications in preventing and treating major human diseases.
Hypoxia Conditioning in Health, Exercise and Sport
Author: Grégoire Millet
Publisher: Routledge
ISBN: 9781032515724
Category : Health & Fitness
Languages : en
Pages : 0
Book Description
While severe hypoxia has detrimental health consequences, the controlled application of hypoxia can be protective and holds great promise as a performance-enhancing and therapeutic intervention. Hypoxia Conditioning in Health, Exercise and Sport: Principles, Mechanisms and Applications delivers an understanding of systemic and molecular mechanisms involved in hypoxia adaptations and examines the most promising forms of hypoxia conditioning with a view to create performance-enhancing strategies for athletes, as well as an offering an examination on clinical applications for numerous pathologies. This cutting-edge book examines how positive physiological adaptations not only acutely enhance tolerance to hypoxia but can also induce sustained health benefits. This has enabled the development and refinement of approaches utilizing hypoxia, strategies also termed hypoxia conditioning, to improve health and performance outcomes. By linking research with recommendations for real-world situations, this volume will serve as an invaluable resource for students, academics, exercise science professionals and sports medicine specialists, especially those in environmental physiology and coaching subjects.
Publisher: Routledge
ISBN: 9781032515724
Category : Health & Fitness
Languages : en
Pages : 0
Book Description
While severe hypoxia has detrimental health consequences, the controlled application of hypoxia can be protective and holds great promise as a performance-enhancing and therapeutic intervention. Hypoxia Conditioning in Health, Exercise and Sport: Principles, Mechanisms and Applications delivers an understanding of systemic and molecular mechanisms involved in hypoxia adaptations and examines the most promising forms of hypoxia conditioning with a view to create performance-enhancing strategies for athletes, as well as an offering an examination on clinical applications for numerous pathologies. This cutting-edge book examines how positive physiological adaptations not only acutely enhance tolerance to hypoxia but can also induce sustained health benefits. This has enabled the development and refinement of approaches utilizing hypoxia, strategies also termed hypoxia conditioning, to improve health and performance outcomes. By linking research with recommendations for real-world situations, this volume will serve as an invaluable resource for students, academics, exercise science professionals and sports medicine specialists, especially those in environmental physiology and coaching subjects.
Respiratory Muscle Training
Author: Alison McConnell
Publisher: Elsevier Health Sciences
ISBN: 0702054550
Category : Medical
Languages : en
Pages : 403
Book Description
Respiratory Muscle Training: theory and practice is the world's first book to provide an "everything-you-need-to-know" guide to respiratory muscle training (RMT). Authored by an internationally-acclaimed expert, it is an evidence-based resource, built upon current scientific knowledge, as well as experience at the cutting-edge of respiratory training in a wide range of settings. The aim of the book is to give readers: 1) an introduction to respiratory physiology and exercise physiology, as well as training theory; 2) an understanding of how disease affects the respiratory muscles and the mechanics of breathing; 3) an insight into the disease-specific, evidence-based benefits of RMT; 4) advice on the application of RMT as a standalone treatment, and as part of a rehabilitation programme; and finally, 5) guidance on the application of functional training techniques to RMT. The book is divided into two parts – theory and practice. Part I provides readers with access to the theoretical building blocks that support practice. It explores the evidence base for RMT as well as the different methods of training respiratory muscles and their respective efficacy. Part II guides the reader through the practical implementation of the most widely validated form of RMT, namely inspiratory muscle resistance training. Finally, over 150 "Functional" RMT exercises are described, which incorporate a stability and/or postural challenge – and address specific movements that provoke dyspnoea. Respiratory Muscle Training: theory and practice is supported by a dedicated website (www.physiobreathe.com), which provides access to the latest information on RMT, as well as video clips of all exercises described in the book. Purchasers will also receive a three-month free trial of the Physiotec software platform (via www.physiotec.ca), which allows clinicians to create bespoke training programmes (including video clips) that can be printed or emailed to patients. - Introductory overviews of respiratory and exercise physiology, as well as training theory - Comprehensive, up-to-date review of respiratory muscle function, breathing mechanics and RMT - Analysis of the interaction between disease and respiratory mechanics, as well as their independent and combined influence upon exercise tolerance - Analysis of the rationale and application of RMT to over 20 clinical conditions, e.g., COPD, heart failure, obesity, mechanical ventilation - Evidence-based guidance on the implementation of inspiratory muscle resistance training - Over 150 functional exercises that incorporate a breathing challenge - www.physiobreathe.com - access up-to-date information, video clips of exercises and a three-month free trial of Physiotec's RMT exercise module (via www.physiotec.ca)
Publisher: Elsevier Health Sciences
ISBN: 0702054550
Category : Medical
Languages : en
Pages : 403
Book Description
Respiratory Muscle Training: theory and practice is the world's first book to provide an "everything-you-need-to-know" guide to respiratory muscle training (RMT). Authored by an internationally-acclaimed expert, it is an evidence-based resource, built upon current scientific knowledge, as well as experience at the cutting-edge of respiratory training in a wide range of settings. The aim of the book is to give readers: 1) an introduction to respiratory physiology and exercise physiology, as well as training theory; 2) an understanding of how disease affects the respiratory muscles and the mechanics of breathing; 3) an insight into the disease-specific, evidence-based benefits of RMT; 4) advice on the application of RMT as a standalone treatment, and as part of a rehabilitation programme; and finally, 5) guidance on the application of functional training techniques to RMT. The book is divided into two parts – theory and practice. Part I provides readers with access to the theoretical building blocks that support practice. It explores the evidence base for RMT as well as the different methods of training respiratory muscles and their respective efficacy. Part II guides the reader through the practical implementation of the most widely validated form of RMT, namely inspiratory muscle resistance training. Finally, over 150 "Functional" RMT exercises are described, which incorporate a stability and/or postural challenge – and address specific movements that provoke dyspnoea. Respiratory Muscle Training: theory and practice is supported by a dedicated website (www.physiobreathe.com), which provides access to the latest information on RMT, as well as video clips of all exercises described in the book. Purchasers will also receive a three-month free trial of the Physiotec software platform (via www.physiotec.ca), which allows clinicians to create bespoke training programmes (including video clips) that can be printed or emailed to patients. - Introductory overviews of respiratory and exercise physiology, as well as training theory - Comprehensive, up-to-date review of respiratory muscle function, breathing mechanics and RMT - Analysis of the interaction between disease and respiratory mechanics, as well as their independent and combined influence upon exercise tolerance - Analysis of the rationale and application of RMT to over 20 clinical conditions, e.g., COPD, heart failure, obesity, mechanical ventilation - Evidence-based guidance on the implementation of inspiratory muscle resistance training - Over 150 functional exercises that incorporate a breathing challenge - www.physiobreathe.com - access up-to-date information, video clips of exercises and a three-month free trial of Physiotec's RMT exercise module (via www.physiotec.ca)
High-Intensity Exercise in Hypoxia - Beneficial Aspects and Potential Drawbacks
Author: Olivier Girard
Publisher: Frontiers Media SA
ISBN: 2889454061
Category :
Languages : en
Pages : 169
Book Description
In the past, ‘traditional’ moderate-intensity continuous training (60-75% peak heart rate) was the type of physical activity most frequently recommended for both athletes and clinical populations (cf. American College of Sports Medicine guidelines). However, growing evidence indicates that high-intensity interval training (80-100% peak heart rate) could actually be associated with larger cardiorespiratory fitness and metabolic function benefits and, thereby, physical performance gains for athletes. Similarly, recent data in obese and hypertensive individuals indicate that various mechanisms – further improvement in endothelial function, reductions in sympathetic neural activity, or in arterial stiffness – might be involved in the larger cardiovascular protective effects associated with training at high exercise intensities. Concerning hypoxic training, similar trends have been observed from ‘traditional’ prolonged altitude sojourns (‘Live High Train High’ or ‘Live High Train Low’), which result in increased hemoglobin mass and blood carrying capacity. Recent innovative ‘Live Low Train High’ methods (‘Resistance Training in Hypoxia’ or ‘Repeated Sprint Training in Hypoxia’) have resulted in peripheral adaptations, such as hypertrophy or delay in muscle fatigue. Other interventions inducing peripheral hypoxia, such as vascular occlusion during endurance/resistance training or remote ischemic preconditioning (i.e. succession of ischemia/reperfusion episodes), have been proposed as methods for improving subsequent exercise performance or altitude tolerance (e.g. reduced severity of acute-mountain sickness symptoms). Postulated mechanisms behind these metabolic, neuro-humoral, hemodynamics, and systemic adaptations include stimulation of nitric oxide synthase, increase in anti-oxidant enzymes, and down-regulation of pro-inflammatory cytokines, although the amount of evidence is not yet significant enough. Improved O2 delivery/utilization conferred by hypoxic training interventions might also be effective in preventing and treating cardiovascular diseases, as well as contributing to improve exercise tolerance and health status of patients. For example, in obese subjects, combining exercise with hypoxic exposure enhances the negative energy balance, which further reduces weight and improves cardio-metabolic health. In hypertensive patients, the larger lowering of blood pressure through the endothelial nitric oxide synthase pathway and the associated compensatory vasodilation is taken to reflect the superiority of exercising in hypoxia compared to normoxia. A hypoxic stimulus, in addition to exercise at high vs. moderate intensity, has the potential to further ameliorate various aspects of the vascular function, as observed in healthy populations. This may have clinical implications for the reduction of cardiovascular risks. Key open questions are therefore of interest for patients suffering from chronic vascular or cellular hypoxia (e.g. work-rest or ischemia/reperfusion intermittent pattern; exercise intensity; hypoxic severity and exposure duration; type of hypoxia (normobaric vs. hypobaric); health risks; magnitude and maintenance of the benefits). Outside any potential beneficial effects of exercising in O2-deprived environments, there may also be long-term adverse consequences of chronic intermittent severe hypoxia. Sleep apnea syndrome, for instance, leads to oxidative stress and the production of reactive oxygen species, and ultimately systemic inflammation. Postulated pathophysiological changes associated with intermittent hypoxic exposure include alteration in baroreflex activity, increase in pulmonary arterial pressure and hematocrit, changes in heart structure and function, and an alteration in endothelial-dependent vasodilation in cerebral and muscular arteries. There is a need to explore the combination of exercising in hypoxia and association of hypertension, developmental defects, neuro-pathological and neuro-cognitive deficits, enhanced susceptibility to oxidative injury, and possibly increased myocardial and cerebral infarction in individuals sensitive to hypoxic stress. The aim of this Research Topic is to shed more light on the transcriptional, vascular, hemodynamics, neuro-humoral, and systemic consequences of training at high intensities under various hypoxic conditions.
Publisher: Frontiers Media SA
ISBN: 2889454061
Category :
Languages : en
Pages : 169
Book Description
In the past, ‘traditional’ moderate-intensity continuous training (60-75% peak heart rate) was the type of physical activity most frequently recommended for both athletes and clinical populations (cf. American College of Sports Medicine guidelines). However, growing evidence indicates that high-intensity interval training (80-100% peak heart rate) could actually be associated with larger cardiorespiratory fitness and metabolic function benefits and, thereby, physical performance gains for athletes. Similarly, recent data in obese and hypertensive individuals indicate that various mechanisms – further improvement in endothelial function, reductions in sympathetic neural activity, or in arterial stiffness – might be involved in the larger cardiovascular protective effects associated with training at high exercise intensities. Concerning hypoxic training, similar trends have been observed from ‘traditional’ prolonged altitude sojourns (‘Live High Train High’ or ‘Live High Train Low’), which result in increased hemoglobin mass and blood carrying capacity. Recent innovative ‘Live Low Train High’ methods (‘Resistance Training in Hypoxia’ or ‘Repeated Sprint Training in Hypoxia’) have resulted in peripheral adaptations, such as hypertrophy or delay in muscle fatigue. Other interventions inducing peripheral hypoxia, such as vascular occlusion during endurance/resistance training or remote ischemic preconditioning (i.e. succession of ischemia/reperfusion episodes), have been proposed as methods for improving subsequent exercise performance or altitude tolerance (e.g. reduced severity of acute-mountain sickness symptoms). Postulated mechanisms behind these metabolic, neuro-humoral, hemodynamics, and systemic adaptations include stimulation of nitric oxide synthase, increase in anti-oxidant enzymes, and down-regulation of pro-inflammatory cytokines, although the amount of evidence is not yet significant enough. Improved O2 delivery/utilization conferred by hypoxic training interventions might also be effective in preventing and treating cardiovascular diseases, as well as contributing to improve exercise tolerance and health status of patients. For example, in obese subjects, combining exercise with hypoxic exposure enhances the negative energy balance, which further reduces weight and improves cardio-metabolic health. In hypertensive patients, the larger lowering of blood pressure through the endothelial nitric oxide synthase pathway and the associated compensatory vasodilation is taken to reflect the superiority of exercising in hypoxia compared to normoxia. A hypoxic stimulus, in addition to exercise at high vs. moderate intensity, has the potential to further ameliorate various aspects of the vascular function, as observed in healthy populations. This may have clinical implications for the reduction of cardiovascular risks. Key open questions are therefore of interest for patients suffering from chronic vascular or cellular hypoxia (e.g. work-rest or ischemia/reperfusion intermittent pattern; exercise intensity; hypoxic severity and exposure duration; type of hypoxia (normobaric vs. hypobaric); health risks; magnitude and maintenance of the benefits). Outside any potential beneficial effects of exercising in O2-deprived environments, there may also be long-term adverse consequences of chronic intermittent severe hypoxia. Sleep apnea syndrome, for instance, leads to oxidative stress and the production of reactive oxygen species, and ultimately systemic inflammation. Postulated pathophysiological changes associated with intermittent hypoxic exposure include alteration in baroreflex activity, increase in pulmonary arterial pressure and hematocrit, changes in heart structure and function, and an alteration in endothelial-dependent vasodilation in cerebral and muscular arteries. There is a need to explore the combination of exercising in hypoxia and association of hypertension, developmental defects, neuro-pathological and neuro-cognitive deficits, enhanced susceptibility to oxidative injury, and possibly increased myocardial and cerebral infarction in individuals sensitive to hypoxic stress. The aim of this Research Topic is to shed more light on the transcriptional, vascular, hemodynamics, neuro-humoral, and systemic consequences of training at high intensities under various hypoxic conditions.
Antioxidants in Sport Nutrition
Author: Manfred Lamprecht
Publisher: CRC Press
ISBN: 1466567570
Category : Medical
Languages : en
Pages : 304
Book Description
The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.
Publisher: CRC Press
ISBN: 1466567570
Category : Medical
Languages : en
Pages : 304
Book Description
The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.
Hypoxia and exercise: Tissue specific and systemic adaptive responses
Author: Xu Yan
Publisher: Frontiers Media SA
ISBN: 2832509983
Category : Science
Languages : en
Pages : 153
Book Description
Publisher: Frontiers Media SA
ISBN: 2832509983
Category : Science
Languages : en
Pages : 153
Book Description
Encyclopedia of Exercise Medicine in Health and Disease
Author: Frank C. Mooren
Publisher: Springer
ISBN: 9783540360650
Category : Medical
Languages : en
Pages : 0
Book Description
The Encyclopedia of Exercise Medicine is intelligently structured, easy accessible and user-friendly: A-Z format, clear, concise language and uniform essay structure as well as extensive cross references between keywords and related articles enables efficient searches in a user-friendly manner both for experts and newcomers. It is intended to be a comprehensive up-to-date data base on the adaptation of the human body to exercise and on the therapeutic use of exercise with up to 2,000 keywords. It covers all aspects within the full range of modern exercise medicine of each particular scientific discipline (cancer, parasitology, aging, etc.). This includes information on methodological approaches to measuring the principle components of motor fitness, and practical aspects of their enhancement by trainings regimes as well as by nutrition and the application of drugs. Such a wide range of entries, all written by leading experts in their respective fields, will therefore address both the basic/clinical scientist as well as the practitioner. Moreover, the Encyclopedia of Exercise Medicine is aimed at people in related fields, health care professionals, physiotherapists, trainers, students, informed athletes and interested laypersons. It is available both in print and as a fully searchable and hyperlinked electronic online edition.
Publisher: Springer
ISBN: 9783540360650
Category : Medical
Languages : en
Pages : 0
Book Description
The Encyclopedia of Exercise Medicine is intelligently structured, easy accessible and user-friendly: A-Z format, clear, concise language and uniform essay structure as well as extensive cross references between keywords and related articles enables efficient searches in a user-friendly manner both for experts and newcomers. It is intended to be a comprehensive up-to-date data base on the adaptation of the human body to exercise and on the therapeutic use of exercise with up to 2,000 keywords. It covers all aspects within the full range of modern exercise medicine of each particular scientific discipline (cancer, parasitology, aging, etc.). This includes information on methodological approaches to measuring the principle components of motor fitness, and practical aspects of their enhancement by trainings regimes as well as by nutrition and the application of drugs. Such a wide range of entries, all written by leading experts in their respective fields, will therefore address both the basic/clinical scientist as well as the practitioner. Moreover, the Encyclopedia of Exercise Medicine is aimed at people in related fields, health care professionals, physiotherapists, trainers, students, informed athletes and interested laypersons. It is available both in print and as a fully searchable and hyperlinked electronic online edition.
Pulmonary Gas Exchange
Author: G. Kim Prisk
Publisher: Biota Publishing
ISBN: 1615044515
Category : Science
Languages : en
Pages : 88
Book Description
The lung receives the entire cardiac output from the right heart and must load oxygen onto and unload carbon dioxide from perfusing blood in the correct amounts to meet the metabolic needs of the body. It does so through the process of passive diffusion. Effective diffusion is accomplished by intricate parallel structures of airways and blood vessels designed to bring ventilation and perfusion together in an appropriate ratio in the same place and at the same time. Gas exchange is determined by the ventilation-perfusion ratio in each of the gas exchange units of the lung. In the normal lung ventilation and perfusion are well matched, and the ventilation-perfusion ratio is remarkably uniform among lung units, such that the partial pressure of oxygen in the blood leaving the pulmonary capillaries is less than 10 Torr lower than that in the alveolar space. In disease, the disruption to ventilation-perfusion matching and to diffusional transport may result in inefficient gas exchange and arterial hypoxemia. This volume covers the basics of pulmonary gas exchange, providing a central understanding of the processes involved, the interactions between the components upon which gas exchange depends, and basic equations of the process.
Publisher: Biota Publishing
ISBN: 1615044515
Category : Science
Languages : en
Pages : 88
Book Description
The lung receives the entire cardiac output from the right heart and must load oxygen onto and unload carbon dioxide from perfusing blood in the correct amounts to meet the metabolic needs of the body. It does so through the process of passive diffusion. Effective diffusion is accomplished by intricate parallel structures of airways and blood vessels designed to bring ventilation and perfusion together in an appropriate ratio in the same place and at the same time. Gas exchange is determined by the ventilation-perfusion ratio in each of the gas exchange units of the lung. In the normal lung ventilation and perfusion are well matched, and the ventilation-perfusion ratio is remarkably uniform among lung units, such that the partial pressure of oxygen in the blood leaving the pulmonary capillaries is less than 10 Torr lower than that in the alveolar space. In disease, the disruption to ventilation-perfusion matching and to diffusional transport may result in inefficient gas exchange and arterial hypoxemia. This volume covers the basics of pulmonary gas exchange, providing a central understanding of the processes involved, the interactions between the components upon which gas exchange depends, and basic equations of the process.