An Introduction to Bioreactor Hydrodynamics and Gas-Liquid Mass Transfer PDF Download
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Author: Enes Kadic
Publisher: John Wiley & Sons
ISBN: 1118869834
Category : Science
Languages : en
Pages : 330
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Book Description
Reviews and compares the major types of bioreactors, defines their pros and cons, and identifies research needs and figures of merit that have yet to be addressed Describes common modes of operation in bioreactors Covers the three common bioreactor types, including stirred-tank bioreactors, bubble column bioreactors, and airlift bioreactors Details less common bioreactors types, including fixed bed bioreactors and novel bioreactor designs Discusses advantages and disadvantages of each bioreactor and provides a procedure for optimal bioreactor selection based on current process needs Reviews the problems of bioreactor selection globally while considering all bioreactor options rather than concentrating on one specific bioreactor type
Author: Enes Kadic
Publisher: John Wiley & Sons
ISBN: 1118869834
Category : Science
Languages : en
Pages : 330
Get Book Here
Book Description
Reviews and compares the major types of bioreactors, defines their pros and cons, and identifies research needs and figures of merit that have yet to be addressed Describes common modes of operation in bioreactors Covers the three common bioreactor types, including stirred-tank bioreactors, bubble column bioreactors, and airlift bioreactors Details less common bioreactors types, including fixed bed bioreactors and novel bioreactor designs Discusses advantages and disadvantages of each bioreactor and provides a procedure for optimal bioreactor selection based on current process needs Reviews the problems of bioreactor selection globally while considering all bioreactor options rather than concentrating on one specific bioreactor type
Author: M. Y. Chisti
Publisher:
ISBN:
Category :
Languages : en
Pages : 323
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Book Description
Author: M. Y. Chisti
Publisher: Springer
ISBN:
Category : Science
Languages : en
Pages : 368
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Book Description
Author: Roger King
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 460
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Book Description
Author: Jerome Morchain
Publisher: Elsevier
ISBN: 0081011660
Category : Technology & Engineering
Languages : en
Pages : 220
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Book Description
Dynamic simulation of bioreactors is a challenge for both the industrial and academic worlds. Beyond the large number of physical and biological phenomena to be considered and the wide range of scales involved, the central difficulty lies in the need to account for the dynamic behavior of suspended microorganisms. In the case of chemical reactors, knowledge of the thermodynamic equilibrium laws at the interfaces makes it possible to produce macroscopic models by integrating local laws. Microorganisms, on the other hand, have the ability to modulate the rate of substrate assimilation. Moreover, the nature of the biochemical transformations results from a compromise between the needs of the cell and the available resources. This book revisits the modeling of bioreactors using a multi-scale approach. It addresses issues related to mixing, phase-to-phase transfers and the adaptation of microorganisms to variations in concentration, and explores the use of population balances for the simulation of bioreactors. By adopting a multidisciplinary perspective that draws on process engineering, fluid mechanics and microbiology, this book sheds new light on the particularity of bioprocesses in relation to physical and chemical phenomena. Presents a multiphase description of bioreactor modeling Includes a combination of concepts issued from different scientific fields to address a practical issue Provides a detailed description of the population balance concept as applied to biological systems Covers a set of illustrative examples of the interaction between hydrodynamics and biological response
Author: Joaquim M.S. Cabral
Publisher: CRC Press
ISBN: 0203303040
Category : Science
Languages : en
Pages : 550
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Book Description
Bioreaction engineering is fundamental to the optimization of biotechnological processes and the production of biochemicals by enzymes, microbial, plant and animal cells and higher organisms. A reference text for postgraduate students and researchers in biochemical engineering and bioreactor design, Multiphase Bioreactor Design describes the
Author: Stanimir S. Drandev
Publisher:
ISBN:
Category :
Languages : en
Pages : 184
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Book Description
Despite the increasing importance of air-lift reactors, very little published information is available on how the ratio of aerated to non-aerated cross-sectional areas (Ad/Ar) of the reactor, and the aerating system affect the oxygen mass transfer, energy efficiency and other performance characteristics. The main goal of this work was to define the optimal operating conditions in terms of oxygen mass transfer, hydrodynamics and energy utilization in a rectangular air-lift reactor for use in a biological fuel cell by identifying its oxygen mass transfer coefficient and liquid circulation behavior. A new empirical model for the dependence of the mass transfer coefficient on the non-aerated to aerated compartment ratio in the air-lift reactor was developed and used for optimization of the operating conditions. We believe that this work may be useful for the design and optimization of biochemical and other processes that require air-lift reactors.
Author: Gregory T. Benz
Publisher: John Wiley & Sons
ISBN: 1119650496
Category : Technology & Engineering
Languages : en
Pages : 448
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Book Description
AGITATOR DESIGN FOR GAS-LIQUID FERMENTERS AND BIOREACTORS Explore the basic principles and concepts of the design of agitation systems for fermenters and bioreactors Agitator Design for Gas-Liquid Fermenters and Bioreactors delivers a concise treatment and explanation of how to design mechanically sound agitation systems that will perform the agitation process function efficiently and economically. The book covers agitator fundamentals, impeller systems, optimum power and air flow at peak mass transfer calculations, optimizing operation for minimum energy per batch, heat transfer surfaces and calculations, shaft seal considerations, mounting methods, mechanical design, and vendor evaluation. The accomplished author has created a practical and hands-on tool that discusses the subject of agitation systems from first principles all the way to implementation in the real world. Step-by-step processes are included throughout the book to assist engineers, chemists, and other scientists in the design, construction, installation, and maintenance of these systems. Readers will also benefit from the inclusion of: A thorough introduction to the design of gas-liquid fermenters and bioreactors An exploration of agitator fundamentals, impeller systems, optimum power, and air flow at peak mass transfer calculations A discussion of how to optimize operation for minimum energy per batch Step-by-step processes to assist engineers, chemists, and scientists An examination of heat transfer surfaces and calculations, shaft seal considerations, mounting methods, and mechanical design Perfect for chemical engineers, mechanical engineers, process engineers, chemists, and materials scientists, Agitator Design for Gas-Liquid Fermenters and Bioreactors will also earn a place in the libraries of pharmaceutical scientists seeking a one-stop resource for designing mechanically sound agitation systems.
Author: Nucharee Rasrikrangkrai
Publisher:
ISBN: 9789741738144
Category :
Languages : en
Pages : 228
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Book Description
This work investigated the performance of various filters in the nitrification process. The modeled systems included the submerged filter, the packed bed airlift filter, the fluidized bed airlift filter. The commonly used trickling filter was also employed as a base experimental case for the purpose of comparison. Firstly, the investigation on the hydrodynamics and gas-liquid mass transfer of the various filters was carried out. It was found that the gas holdup in all the systems increased with an increase in the gas throughput to the system. The submerged filter seemed to be the best among all the systems under investigation as it provided the highest gas holdup and gas-liquid mass transfer rate. The fluidized bed airlift filter, on the other hand, was the poorest among the three filters. This was because the operating conditions employed in the nitrification process were not adequate for the perfect fluidized bed condition. Hence, there existed a "still bed condition" where a large fraction of packing was not fluidized and this caused high pressure drop in the system. This led to a larger gas bubbles which reduced the gas-liquid mass transfer area. Also the gas holdup in this filter was the lowest because large bubbles were formed which left the system more rapidly than smaller bubbles found in other systems. However, certain conditions could lead to a perfect fluidized bed condition and the performance of the system at this condition was found to be comparative to the packed bed airlift system. In terms of nitrification rate, the packed bed airlift filter was found to be the most effective system. The removal rate from the submerged filter was observed to be relatively high at all operating conditions. The performance of fluidized bed airlift filter, however, depended on several factors. At low Ad/Ar, the system was not effective in removing ammonia. This was because the system could not reach full fluidizing condition in the range of gas superficial velocity employed in this work. Increasing Ad/Ar helped create a better fluidizing condition in this system and augmented the removal rate in the fluidized bed airlift filter. However, the specific ammonia removal rate obtained from the fluidized bed at high Ad/Ar was still lower than that obtained from the packed bed airlift filter at low Ad/Ar.
Author: Norton G. McDuffie
Publisher: Butterworth-Heinemann
ISBN: 1483221083
Category : Technology & Engineering
Languages : en
Pages : 150
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Book Description
Bioreactor Design Fundamentals presents the development in the bioreactor field. This book discusses the applications of biological kinetics and thermodynamics. Organized into seven chapters, this book begins with an overview of the design of biological reactors that involves determining operating conditions, sizing the reactor, controlling temperature and sterility, and controlling operating variables. This text then examines the significance of pH considerations in biological reactor and process design. Other chapters consider enzyme kinetics and the equations most commonly used as models for overall enzyme kinetics. This book discusses as well the mass transfer rates in bioreactors, which are significant because of their effects on some chemical reaction rates in transformations by enzymes or by living cells. The final chapter deals with the ideal state of the continuous stirred-tank reactors (CSTRs). This book is a valuable resource for biochemical engineers and industrial microbiologists.
