How Family History and Race Influence Prostate Cancer Screening PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download How Family History and Race Influence Prostate Cancer Screening PDF full book. Access full book title How Family History and Race Influence Prostate Cancer Screening by Benjamin Sener Dunlap. Download full books in PDF and EPUB format.
Author: Benjamin Sener Dunlap
Publisher:
ISBN:
Category :
Languages : en
Pages : 22
Get Book Here
Book Description
Background: Most major U.S. medical organizations recommend that screening for prostate cancer using the prostate-specific antigen (PSA) test should be based on individual patient preferences. Men with risk factors for prostate cancer diagnosis and mortality may have different preferences for screening than men without any risk factors. Methods: We used nationally-representative survey data from the 2005 and 2010 National Health Interview Survey to assess PSA-screening patterns by age, family history of prostate cancer and race among men in the United States over 40 years old using bivariate and multivariable logistic regression. Results: Men with any family history of prostate cancer were more likely to be screened using the PSA test in the last two years at any age (OR=2.2, 95% CI 1.8-2.6), and men with a father and brother diagnosed were more likely to be screened than men with only a father diagnosed, after adjustment (p=0.019). Younger (40-54 year old) African-American or black men had a higher odds of being screened than White, non-Hispanic men of the same age, after adjustment (OR=1.5, 95% CI=1.2-1.9), but this same adjusted comparison within other age groups indicated no significant difference in screening rates by race (age 55-69 years old: OR=1.0, 95% CI=0.8-1.3; age 70 years or more: OR=-0.9, 95% CI=0.7-1.3). Conclusion: There is considerable heterogeneity in PSA-screening practices. A family history of prostate cancer, and to a limited degree black or African-American race, both contribute to increased odds of undergoing screening. Understanding how to discuss risk factors with men to ensure individual patient preferences are appropriately integrated into screening decisions should be a priority for providers.
Author: Benjamin Sener Dunlap
Publisher:
ISBN:
Category :
Languages : en
Pages : 22
Get Book Here
Book Description
Background: Most major U.S. medical organizations recommend that screening for prostate cancer using the prostate-specific antigen (PSA) test should be based on individual patient preferences. Men with risk factors for prostate cancer diagnosis and mortality may have different preferences for screening than men without any risk factors. Methods: We used nationally-representative survey data from the 2005 and 2010 National Health Interview Survey to assess PSA-screening patterns by age, family history of prostate cancer and race among men in the United States over 40 years old using bivariate and multivariable logistic regression. Results: Men with any family history of prostate cancer were more likely to be screened using the PSA test in the last two years at any age (OR=2.2, 95% CI 1.8-2.6), and men with a father and brother diagnosed were more likely to be screened than men with only a father diagnosed, after adjustment (p=0.019). Younger (40-54 year old) African-American or black men had a higher odds of being screened than White, non-Hispanic men of the same age, after adjustment (OR=1.5, 95% CI=1.2-1.9), but this same adjusted comparison within other age groups indicated no significant difference in screening rates by race (age 55-69 years old: OR=1.0, 95% CI=0.8-1.3; age 70 years or more: OR=-0.9, 95% CI=0.7-1.3). Conclusion: There is considerable heterogeneity in PSA-screening practices. A family history of prostate cancer, and to a limited degree black or African-American race, both contribute to increased odds of undergoing screening. Understanding how to discuss risk factors with men to ensure individual patient preferences are appropriately integrated into screening decisions should be a priority for providers.
Author: Michelle Elizabeth McDowell
Publisher:
ISBN:
Category : Electronic dissertations
Languages : en
Pages : 764
Get Book Here
Book Description
Abstract : The benefits of early detection screening for prostate cancer are still unclear and current screening guidelines recommend that men make an informed, personal decision based on an understanding of the risks, benefits, and uncertainties associated with screening. Men with a first-degree family history of prostate cancer are at more than double the risk of being diagnosed with prostate cancer than are men without a family history. However, contrary to predictions put forward in previous research, although men with a family history of prostate cancer report greater risk perceptions and prostate cancer screening behaviour, increased risk perceptions do not predict screening. Previous research on how men with a family history of prostate cancer integrate heightened familial risk information into what is already a complex health decision has neglected to examine how men understand, combine, and weigh information about prostate cancer risk and the uncertainties of early detection screening to reach their decisions. The aim of the current thesis was to address these issues by applying three major theoretical models of judgement and decision-making to examine prostate cancer screening decisions for men with a family history and comparing their decisional process with that of men without a family history.
Author: Jack Cuzick
Publisher: Springer Science & Business Media
ISBN: 3642451950
Category : Medical
Languages : en
Pages : 167
Get Book Here
Book Description
Prostate cancer is by far the most common cancer in men and the second leading cause of death due to cancer. It comprises a mixed group of tumours displaying varying clinical behaviour: while some have a very aggressive course, others are rather indolent. Prevention of prostate cancer and discrimination between aggressive and indolent forms are important clinical goals and the acquisition of significant new evidence on means of achieving these aims makes this book particularly timely. A wide range of topics are covered by leading authorities in the field. The biology and natural history of prostate cancer are reviewed and the role of lifestyle and dietary factors, assessed. Detailed attention is paid to risk prediction biomarkers and to the role of novel high-throughput nucleic acid-based technologies in improving risk prediction and thereby allowing tailored approaches to cancer prevention. Potential means of chemoprevention of prostate cancer are also reviewed in depth, covering the very positive new data on the impact of aspirin as well as evidence regarding 5α-reductase inhibitors, DFMO and lycopene. Guidance is provided on the differentiation of aggressive from indolent disease and the policy and research implications of recent findings are examined. This book will be of interest to both clinicians and researchers.
Author: Amelie G. Ramirez
Publisher: Springer Nature
ISBN: 303029286X
Category : Medical
Languages : en
Pages : 320
Get Book Here
Book Description
This open access book gives an overview of the sessions, panel discussions, and outcomes of the Advancing the Science of Cancer in Latinos conference, held in February 2018 in San Antonio, Texas, USA, and hosted by the Mays Cancer Center and the Institute for Health Promotion Research at UT Health San Antonio. Latinos – the largest, youngest, and fastest-growing minority group in the United States – are expected to face a 142% rise in cancer cases in coming years. Although there has been substantial advancement in cancer prevention, screening, diagnosis, and treatment over the past few decades, addressing Latino cancer health disparities has not nearly kept pace with progress. The diverse and dynamic group of speakers and panelists brought together at the Advancing the Science of Cancer in Latinos conference provided in-depth insights as well as progress and actionable goals for Latino-focused basic science research, clinical best practices, community interventions, and what can be done by way of prevention, screening, diagnosis, and treatment of cancer in Latinos. These insights have been translated into the chapters included in this compendium; the chapters summarize the presentations and include current knowledge in the specific topic areas, identified gaps, and top priority areas for future cancer research in Latinos. Topics included among the chapters: Colorectal cancer disparities in Latinos: Genes vs. Environment Breast cancer risk and mortality in women of Latin American origin Differential cancer risk in Latinos: The role of diet Overcoming barriers for Latinos on cancer clinical trials Es tiempo: Engaging Latinas in cervical cancer research Emerging policies in U.S. health care Advancing the Science of Cancer in Latinos proves to be an indispensable resource offering key insights into actionable targets for basic science research, suggestions for clinical best practices and community interventions, and novel strategies and advocacy opportunities to reduce health disparities in Latino communities. It will find an engaged audience among researchers, academics, physicians and other healthcare professionals, patient advocates, students, and others with an interest in the broad field of Latino cancer.
Author: Scott M. Dehm
Publisher: Springer Nature
ISBN: 303032656X
Category : Medical
Languages : en
Pages : 483
Get Book Here
Book Description
The purpose of this book is to provide a contemporary overview of the causes and consequences of prostate cancer from a cellular and genetic perspective. Written by experts in the fields of epidemiology, toxicology, cell biology, genetics, genomics, cell-cell interactions, cell signaling, hormone signaling, and transcriptional regulation, the text covers aspects of prostate cancer from disease initiation to metastasis. Chapters explore in depth the cells of origin for prostate cancer, its genomic subtypes, neural transcription factors in disease progression, epigenetic regulation of chromatin, and many other topics. This book distinguishes itself from other texts on prostate cancer by its focus on cellular and genetic mechanisms, as opposed to clinical diagnosis and management. As a result, this book will be of broad interest to basic and translational scientists with familiarity of these topics, as well as to trainees at earlier stages of their research careers.
Author: Gayathri Sridhar
Publisher:
ISBN:
Category :
Languages : en
Pages :
Get Book Here
Book Description
This is a compilation of 3 abstracts for the three manuscripts included in this dissertation. I. Meta-Analysis: Racial Disparities in Prostate Cancer Survival: Prostate cancer is the second leading cause of cancer-related mortality in men. Previous studies have drawn inconsistent conclusions on racial differences in prostate cancer survival. This meta-analysis was conducted to investigate the relationship between race and survival from prostate cancer. A systematic review of published articles from 1968 to 2007 assessing survival from prostate cancer among African American and White men was conducted. The search yielded 20 eligible published manuscripts. Analysis of unadjusted studies showed African American men have an increased risk of all-cause mortality (Hazard ratio (HR) = 1.47, 95% confidence interval (CI): 1.31, 1.65, P
Author: SEER Program (National Cancer Institute (U.S.))
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 104
Get Book Here
Book Description
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309170133
Category : Medical
Languages : en
Pages : 564
Get Book Here
Book Description
Cancer ranks second only to heart disease as a leading cause of death in the United States, making it a tremendous burden in years of life lost, patient suffering, and economic costs. Fulfilling the Potential for Cancer Prevention and Early Detection reviews the proof that we can dramatically reduce cancer rates. The National Cancer Policy Board, part of the Institute of Medicine, outlines a national strategy to realize the promise of cancer prevention and early detection, including specific and wide-ranging recommendations. Offering a wealth of information and directly addressing major controversies, the book includes: A detailed look at how significantly cancer could be reduced through lifestyle changes, evaluating approaches used to alter eating, smoking, and exercise habits. An analysis of the intuitive notion that screening for cancer leads to improved health outcomes, including a discussion of screening methods, potential risks, and current recommendations. An examination of cancer prevention and control opportunities in primary health care delivery settings, including a review of interventions aimed at improving provider performance. Reviews of professional education and training programs, research trends and opportunities, and federal programs that support cancer prevention and early detection. This in-depth volume will be of interest to policy analysts, cancer and public health specialists, health care administrators and providers, researchers, insurers, medical journalists, and patient advocates.
Author: Andrew W. Bruce
Publisher: Springer Science & Business Media
ISBN: 1447113985
Category : Medical
Languages : en
Pages : 363
Get Book Here
Book Description
Carcinoma of the prostate increasingly dominates the attention of urologists for both scientific and clinical reasons. The search for an explanation and the prediction of the variable behaviour of the malignant prostatic cell continues unabated. The search for more precise tumour staging and more effective treatment is equally vigorous. Editors Andrew Bruce and John Trachtenberg have assembled acknowledged leaders in prostate cancer to present those areas of direct interest to the clinician. There are a number of other topics that might have been considered but most of these, such as experimental tumour models or biochemical factors affecting cell growth, still lack immediate application for the clinician. Carcinoma of the prostate continues to have its highest incidence in the western world, and the difference in comparison with the incidence in the Far East appears to be real and not masked by diagnostic or other factors. A number of other epidemiological aspects need careful analysis: Is the incidence increasing? Is the survival improving? Is the prognosis worse in the younger patient? Epidemiological data are easily misused and misinterpreted so that a precise analysis of the known facts makes an important opening chapter to this book.
Author:
Publisher: Office of the Surgeon General
ISBN:
Category : Health & Fitness
Languages : en
Pages : 80
Get Book Here
Book Description
Promotes the recognition, treatment, and prevention of conditions of overweight and obesity in the United States.
