High-Tc SQUIDs for Biomedical Applications: Immunoassays, Magnetoencephalography, and Ultra-Low Field Magnetic Resonance Imaging

High-Tc SQUIDs for Biomedical Applications: Immunoassays, Magnetoencephalography, and Ultra-Low Field Magnetic Resonance Imaging PDF Author: Fredrik Öisjöen
Publisher: Springer Science & Business Media
ISBN: 3642313566
Category : Technology & Engineering
Languages : en
Pages : 111

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Book Description
This thesis describes the challenging task of developing high critical temperature superconducting quantum interference devices (high-Tc SQUIDs) and using them as sensors for biomedical applications, including magnetic immunoassays, magnetoencephalography and magnetic resonance imaging (MRI). The first part of this work discusses the development of fast magnetic immunoassays, which can be used to improve the sensitivity, or to create new, unique point-of-care diagnostics systems. The second part shows that high-Tc SQUIDs might make magnetoencephalography more available, thus opening the field of high-Tc SQUID-based magnetoencephalography for recording brain functions. This technique can be combined with ultra-low field MRI which is discussed in the last part. This combination may provide a new unique tool for studies of brain functions. This work does not simply improve on existing technology but opens possibilities for novel advanced medical devices and techniques.

High-Tc SQUIDs for Biomedical Applications: Immunoassays, Magnetoencephalography, and Ultra-Low Field Magnetic Resonance Imaging

High-Tc SQUIDs for Biomedical Applications: Immunoassays, Magnetoencephalography, and Ultra-Low Field Magnetic Resonance Imaging PDF Author: Fredrik Öisjöen
Publisher: Springer Science & Business Media
ISBN: 3642313566
Category : Technology & Engineering
Languages : en
Pages : 111

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Book Description
This thesis describes the challenging task of developing high critical temperature superconducting quantum interference devices (high-Tc SQUIDs) and using them as sensors for biomedical applications, including magnetic immunoassays, magnetoencephalography and magnetic resonance imaging (MRI). The first part of this work discusses the development of fast magnetic immunoassays, which can be used to improve the sensitivity, or to create new, unique point-of-care diagnostics systems. The second part shows that high-Tc SQUIDs might make magnetoencephalography more available, thus opening the field of high-Tc SQUID-based magnetoencephalography for recording brain functions. This technique can be combined with ultra-low field MRI which is discussed in the last part. This combination may provide a new unique tool for studies of brain functions. This work does not simply improve on existing technology but opens possibilities for novel advanced medical devices and techniques.

High-Tc SQUIDs for Biomedical Applications

High-Tc SQUIDs for Biomedical Applications PDF Author: Frederik Öisjöen
Publisher:
ISBN:
Category : Biomedical engineering
Languages : en
Pages : 97

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Book Description


High -T[subscript C] SQUIDs for Biomedical Applications

High -T[subscript C] SQUIDs for Biomedical Applications PDF Author: Fredrik Öisjöen
Publisher:
ISBN: 9789173856195
Category :
Languages : en
Pages : 150

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Book Description


The SQUID Handbook

The SQUID Handbook PDF Author: John Clarke
Publisher: John Wiley & Sons
ISBN: 3527609504
Category : Science
Languages : en
Pages : 653

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Book Description
This two-volume handbook offers a comprehensive and coordinated presentation of SQUIDs (Superconducting Quantum Interference Devices), including device fundamentals, design, technology, system construction and multiple applications. It is intended to bridge the gap between fundamentals and applications, and will be a valuable textbook reference for graduate students and for professionals engaged in SQUID research and engineering. It will also be of use to specialists in multiple fields of practical SQUID applications, from human brain research and heart diagnostics to airplane and nuclear plant testing to prospecting for oil, minerals and buried ordnance. While the first volume presents the theory and fabrication of SQUIDs, the second volume is devoted to applications. It starts with an important aspect of the analysis of measured magnetic signals generated by current sources (the inverse problem), and includes several chapters devoted to various areas of application, namely biomagnetism (research on and diagnostics of human brain, heart, liver, etc.), detection of extremely weak signals, for example electromagnetic radiation and Nuclear Magnetic Resonance. The volume closes with a chapter on motion detectors and the detection of gravity waves.

Applied Superconductivity

Applied Superconductivity PDF Author: Paul Seidel
Publisher: John Wiley & Sons
ISBN: 3527412093
Category : Technology & Engineering
Languages : en
Pages : 1334

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Book Description
This wide-ranging presentation of applied superconductivity, from fundamentals and materials right up to the details of many applications, is an essential reference for physicists and engineers in academic research as well as in industry. Readers looking for a comprehensive overview on basic effects related to superconductivity and superconducting materials will expand their knowledge and understanding of both low and high Tc superconductors with respect to their application. Technology, preparation and characterization are covered for bulk, single crystals, thins fi lms as well as electronic devices, wires and tapes. The main benefit of this work lies in its broad coverage of significant applications in magnets, power engineering, electronics, sensors and quantum metrology. The reader will find information on superconducting magnets for diverse applications like particle physics, fusion research, medicine, and biomagnetism as well as materials processing. SQUIDs and their usage in medicine or geophysics are thoroughly covered, as are superconducting radiation and particle detectors, aspects on superconductor digital electronics, leading readers to quantum computing and new devices.

Ultra-Low Field Nuclear Magnetic Resonance

Ultra-Low Field Nuclear Magnetic Resonance PDF Author: Robert Kraus Jr.
Publisher: Oxford University Press
ISBN: 0199796513
Category : Medical
Languages : en
Pages : 266

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Book Description
This book is designed to introduce the reader to the field of NMR/MRI at very low magnetic fields, from milli-Tesla to micro-Tesla, the ultra-low field (ULF) regime. The book is focused on applications to imaging the human brain, and hardware methods primarily based upon pre-polarization methods and SQUID-based detection. The goal of the text is to provide insight and tools for the reader to better understand what applications are best served by ULF NMR/MRI approaches. A discussion of the hardware challenges, such as shielding, operation of SQUID sensors in a dynamic field environment, and pulsed magnetic field generation are presented. One goal of the text is to provide the reader a framework of understanding the approaches to estimation and mitigation of low signal-to-noise and long imaging time, which are the main challenges. Special attention is paid to the combination of MEG and ULF MRI, and the benefits and challenges presented by trying to accomplish both with the same hardware. The book discusses the origin of unique relaxation contrast at ULF, and special considerations for image artifacts and how to correct them (i.e. concomitant gradients, ghost artifacts). A general discussion of MRI, with special consideration to the challenges of imaging at ULF and unique opportunities in pulse sequences, is presented. The book also presents an overview of some of the primary applications of ULF NMR/MRI being pursued.

The SQUID Handbook

The SQUID Handbook PDF Author: John Clarke
Publisher: John Wiley & Sons
ISBN: 3527604588
Category : Science
Languages : en
Pages : 409

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Book Description
This two-volume handbook offers a comprehensive and well coordinated presentation of SQUIDs (Superconducting Quantum Interference Devices), including device fundamentals, design, technology, system construction and multiple applications. It is intended to bridge the gap between fundamentals and applications, and will be a valuable textbook reference for graduate students and for professionals engaged in SQUID research and engineering. It will also be of use to specialists in multiple fields of practical SQUID applications, from human brain research and heart diagnostics to airplane and nuclear plant testing to prospecting for oil, minerals and buried ordnance. The first volume contains chapters presenting the theory of SQUIDs, their fabrication from low- and high-temperature superconductors, the necessary readout electronics, and the design and performance of practical direct current (dc) and radio-frequency (rf) SQUIDs. This volume concludes with an overview of the most important SQUID system issues. An appendix summarizes briefly the foundations of superconductivity that are necessary to understand SQUIDs. A glossary and tables of units and constants are also included. The second volume of the handbook will deal with applications of SQUIDs and SQUID systems.

Advances in Condensed-Matter and Materials Physics

Advances in Condensed-Matter and Materials Physics PDF Author: Jagannathan Thirumalai
Publisher: BoD – Books on Demand
ISBN: 1838805540
Category : Science
Languages : en
Pages : 202

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Book Description
This book, Condensed Matter and Material Physics, incorporates the work of multiple authors to enhance the theoretical as well as experimental knowledge of materials. The investigation of crystalline solids is a growing need in the electronics industry. Micro and nano transistors require an in-depth understanding of semiconductors of different groups. Amorphous materials, on the other hand, as non-equilibrium materials are widely applied in sensors and other medical and industrial applications. Superconducting magnets, composite materials, lasers, and many more applications are integral parts of our daily lives. Superfluids, liquid crystals, and polymers are undergoing active research throughout the world. Hence profound information on the nature and application of various materials is in demand. This book bestows on the reader a deep knowledge of physics behind the concepts, perspectives, characteristic properties, and prospects. The book was constructed using 10 contributions from experts in diversified fields of condensed matter and material physics and its technology from over 15 research institutes across the globe.

Magnetism in Medicine

Magnetism in Medicine PDF Author: Wilfried Andrä
Publisher: John Wiley & Sons
ISBN: 3527610189
Category : Medical
Languages : en
Pages : 655

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Book Description
This second, completely updated and extended edition of the only reference work in this growing field of medical physics focuses on biomagnetic instrumentation as well as applications in cardiology and neurology. New chapters have been added on fetal magnetography and magnetic field therapy, as well as the safety aspects of magnetic fields. Written by well-known specialists from Germany, USA, Canada, Japan, the Netherlands and Scandinavia, the result is a manual for researchers in this field as well as for those who apply modern methods based on magnetism in medical practice. It equally provides a detailed overview for newcomers to the field as well as for experts familiar with only one part of the area.

Sensors in Biomedical Applications

Sensors in Biomedical Applications PDF Author: Gabor Harsanyi
Publisher: CRC Press
ISBN: 1420012916
Category : Medical
Languages : en
Pages : 362

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Book Description
While most books contain some information on related sensors topics, they are limited in their scope on biomedical sensors. Sensors in Biomedical Applications: Fundamentals, Design, Technology and Applications is the first systematized book to concentrate on all available and potential sensor devices of biomedical applications! Sensors in Bi