High Resolution NMR of Macromolecules

High Resolution NMR of Macromolecules PDF Author: Frank A. Bovey
Publisher:
ISBN:
Category :
Languages : en
Pages : 476

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Book Description

High Resolution NMR of Macromolecules

High Resolution NMR of Macromolecules PDF Author: Frank A. Bovey
Publisher:
ISBN:
Category :
Languages : en
Pages : 476

Get Book Here

Book Description


High Resolution NMR of Macromolecules

High Resolution NMR of Macromolecules PDF Author: Frank Bovey
Publisher: Elsevier
ISBN: 032314893X
Category : Science
Languages : en
Pages : 477

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Book Description
High Resolution NMR of Macromolecules presents the development in the NMR study of polymers. This book discusses the exciting area of application of NMR to polymer science as the result of the more general accessibility of instruments of high magnetic field. Organized into 15 chapters, this book begins with an overview of the spectral analysis and the dependence of chemical shifts and J couplings on structure. This text then discusses the isomerism in polymer chains without special reference to NMR. Other chapters consider the interpretation of synthetic polymer spectra in terms of structure, stereochemical configuration, conformation, and chain growth mechanism. This book discusses as well the application of high resolution NMR to the study of nucleic acids, which has not been so well developed as that of polypeptides and proteins. The final chapter deals with biopolymers and their model compounds. This book is a valuable resource for chemists and research workers.

High-resolution NMR Techniques in Organic Chemistry

High-resolution NMR Techniques in Organic Chemistry PDF Author: T. Claridge
Publisher: Elsevier
ISBN: 9780080427997
Category : Science
Languages : en
Pages : 408

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Book Description
From the initial observation of proton magnetic resonance in water and in paraffin, the discipline of nuclear magnetic resonance has seen unparalleled growth as an analytical method. Modern NMR spectroscopy is a highly developed, yet still evolving, subject which finds application in chemistry, biology, medicine, materials science and geology. In this book, emphasis is on the more recently developed methods of solution-state NMR applicable to chemical research, which are chosen for their wide applicability and robustness. These have, in many cases, already become established techniques in NMR laboratories, in both academic and industrial establishments. A considerable amount of information and guidance is given on the implementation and execution of the techniques described in this book.

High-Resolution NMR Techniques in Organic Chemistry

High-Resolution NMR Techniques in Organic Chemistry PDF Author: Timothy D.W. Claridge
Publisher: Elsevier
ISBN: 008099993X
Category : Science
Languages : en
Pages : 554

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Book Description
High-Resolution NMR Techniques in Organic Chemistry, Third Edition describes the most important NMR spectroscopy techniques for the structure elucidation of organic molecules and the investigation of their behaviour in solution. Appropriate for advanced undergraduate and graduate students, research chemists and NMR facility managers, this thorough revision covers practical aspects of NMR techniques and instrumentation, data collection, and spectrum interpretation. It describes all major classes of one- and two-dimensional NMR experiments including homonuclear and heteronuclear correlations, the nuclear Overhauser effect, diffusion measurements, and techniques for studying protein–ligand interactions. A trusted authority on this critical expertise, High-Resolution NMR Techniques in Organic Chemistry, Third Edition is an essential resource for every chemist and NMR spectroscopist.

Biological NMR Spectroscopy

Biological NMR Spectroscopy PDF Author: John L. Markley
Publisher: Oxford University Press
ISBN: 0195094689
Category : Medical
Languages : en
Pages : 375

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Book Description
This book presents a critical assessment of progress on the use of nuclear magnetic resonance spectroscopy to determine the structure of proteins, including brief reviews of the history of the field along with coverage of current clinical and in vivo applications. The book, in honor of Oleg Jardetsky, one of the pioneers of the field, is edited by two of the most highly respected investigators using NMR, and features contributions by most of the leading workers in the field. It will be valued as a landmark publication that presents the state-of-the-art perspectives regarding one of today's most important technologies.

NMR with Biological Macromolecules in Solution

NMR with Biological Macromolecules in Solution PDF Author: Kurt Wüthrich
Publisher: World Scientific Publishing Company
ISBN: 9789811235788
Category : Science
Languages : en
Pages : 270

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Book Description
The book provides insights into the research of the Kurt Wüthrich laboratories from 1996-2020. During this time period, the technique of nuclear magnetic resonance (NMR) spectroscopy in solution went through several breakthroughs, while maturing into a standard method of structural biology. With the introduction of TROSY (transverse relaxation-optimized spectroscopy), the range of accessible molecular sizes was extended about thirty-fold, and efficient protein structure determination resulted from the demands of the structural genomics initiative. Applications in fundamental biology and biomedicine include studies of prion proteins and prion diseases (TSEs), the SARS-Corona virus proteome, trans-membrane signalling by G protein-coupled receptors (GPCRs), and signal transfer by pheromones.Key publications from the Kurt Wüthrich laboratories are placed in perspective, providing insights into new aspects of NMR spectroscopy in structural biology. In addition to methods development, this includes applications in diverse areas of biological research, such as prion proteins and their role in transmissible spongiform encephalopathies (TSEs), trans-membrane signal transfer by G protein-coupled receptors (GPCRs), structural characterization of the SARS-Corona virus proteome, metabolic-flux profiling in bacterial cultures, and signal transfers by pheromones.

Syndiotactic Polystyrene

Syndiotactic Polystyrene PDF Author: Jürgen Schellenberg
Publisher: John Wiley & Sons
ISBN: 0470556994
Category : Technology & Engineering
Languages : en
Pages : 486

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Book Description
Syndiotactic Polystyrene (SPS), synthesized in a laboratory for the first time in 1985, has become commercialized in a very short time, with wide acceptance on the global plastics market. Written by leading experts from academia and industry from all over the world, Syndiotactic Polystyrene offers a comprehensive review of all aspects of SPS of interest to both science and industry, from preparation and properties to applications. This essential reference to SPS covers: The preparation of syndiotactic polystyrene by half-metallocenes and other transition metal catalysts The structure and fundamental properties, especially morphology and crystallization and solution behavior The commercial process for SPS manufacturing Properties, processing, and applications of syndiotactic polystyrenes Polymers based on syndiotactic polystyrenes, for example, by functionalization and modification, and nanocomposites Ideal for polymer chemists, physicists, plastics engineers, materials scientists, and all those dealing with plastics manufacturing and processing, this important resource provides the information one needs to compare, select, and integrate an appropriate materials solution for industrial use or research.

High Resolution NMR Spectroscopy: Understanding Molecules and their Electronic Structures

High Resolution NMR Spectroscopy: Understanding Molecules and their Electronic Structures PDF Author:
Publisher: Newnes
ISBN: 0444594140
Category : Science
Languages : en
Pages : 448

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Book Description
The progress in nuclear magnetic resonance (NMR) spectroscopy that took place during the last several decades is observed in both experimental capabilities and theoretical approaches to study the spectral parameters. The scope of NMR spectroscopy for studying a large series of molecular problems has notably broadened. However, at the same time, it requires specialists to fully use its potentialities. This is a notorious problem and it is reflected in the current literature where this spectroscopy is typically only used in a routine way. Also, it is seldom used in several disciplines in which it could be a powerful tool to study many problems. The main aim of this book is to try to help reverse these trends.This book is divided in three parts dealing with 1) high-resolution NMR parameters; 2) methods for understanding high-resolution NMR parameters; and 3) some experimental aspects of high-resolution NMR parameters for studying molecular structures. Each part is divided into chapters written by different specialists who use different methodologies in their work. In turn, each chapter is divided into sections. Some features of the different sections are highlighted: it is expected that part of the readership will be interested only in the basic aspects of some chapters, while other readers will be interested in deepening their understanding of the subject dealt with in them. - Shows how NMR parameters are useful for structure assignment as well as to obtain insight on electronic structures - Emphasis on conceptual aspects - Contributions by specialists who use the discussed methodologies in their everyday work

NMR in Structural Biology

NMR in Structural Biology PDF Author: Kurt Wthrich
Publisher: World Scientific
ISBN: 9789810223847
Category : Science
Languages : en
Pages : 770

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Book Description
The volume presents a survey of the research by Kurt Wthrich and his associates during the period 1965 to 1994. A selection of reprints of original papers on the use of NMR spectroscopy in structural biology is supplemented with an introduction, which outlines the foundations and the historical development of the use of NMR spectroscopy for the determination of three-dimensional structures of biological macromolecules in solution. The original papers are presented in groups highlighting protein structure determination by NMR, studies of dynamic properties and hydration of biological macromolecules, and practical applications of the NMR methodology in fields such as enzymology, transcriptional regulation, immunosuppression and protein folding.

In-cell NMR Spectroscopy

In-cell NMR Spectroscopy PDF Author: Yutaka Ito
Publisher: Royal Society of Chemistry
ISBN: 1839160934
Category : Science
Languages : en
Pages : 322

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Book Description
In-cell NMR spectroscopy is a relatively new field. Despite its short history, recent in-cell NMR-related publications in major journals indicate that this method is receiving significant general attention. This book provides the first informative work specifically focused on in-cell NMR. It details the historical background of in-cell NMR, host cells for in-cell NMR studies, methods for in-cell biological techniques and NMR spectroscopy, applications, and future perspectives. Researchers in biochemistry, biophysics, molecular biology, cell biology, structural biology as well as NMR analysts interested in biological applications will all find this book valuable reading.