High Calorie Diet and the Human Brain

High Calorie Diet and the Human Brain PDF Author: Akhlaq A. Farooqui
Publisher: Springer
ISBN: 3319152548
Category : Medical
Languages : en
Pages : 325

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Book Description
The purpose of this monograph is to present readers with a comprehensive and cutting edge description of neurochemical effects of diet (beneficial and harmful effects) in normal human brain and to discuss how present day diet promotes pathogenesis of stroke, AD, PD, and depression in a manner that is useful not only to students and teachers but also to researchers, dietitians, nutritionists and physicians. A diet in sufficient amount and appropriate macronutrients is essential for optimal health of human body tissues. In brain, over-nutrition, particularly with high-calorie diet, not only alters cellular homeostasis, but also results in changes in the intensity of signal transduction processes in reward centers of the brain resulting in food addiction. Over-nutrition produces detrimental effects on human health in general and brain health in particular because it chronically increases the systemic and brain inflammation and oxidative stress along with induction of insulin resistance and leptin resistance in the brain as well as visceral organs. Onset of chronic inflammation and oxidative stress not only leads to obesity and heart disease, but also promotes type II diabetes and metabolic syndrome, which are risk factors for both acute neural trauma (stroke) and chronic age-related neurodegenerative and neuropsychological disorders, such as Alzheimer disease (AD), Parkinson disease (PD) and depression.

High Calorie Diet and the Human Brain

High Calorie Diet and the Human Brain PDF Author: Akhlaq A. Farooqui
Publisher: Springer
ISBN: 3319152548
Category : Medical
Languages : en
Pages : 325

Get Book Here

Book Description
The purpose of this monograph is to present readers with a comprehensive and cutting edge description of neurochemical effects of diet (beneficial and harmful effects) in normal human brain and to discuss how present day diet promotes pathogenesis of stroke, AD, PD, and depression in a manner that is useful not only to students and teachers but also to researchers, dietitians, nutritionists and physicians. A diet in sufficient amount and appropriate macronutrients is essential for optimal health of human body tissues. In brain, over-nutrition, particularly with high-calorie diet, not only alters cellular homeostasis, but also results in changes in the intensity of signal transduction processes in reward centers of the brain resulting in food addiction. Over-nutrition produces detrimental effects on human health in general and brain health in particular because it chronically increases the systemic and brain inflammation and oxidative stress along with induction of insulin resistance and leptin resistance in the brain as well as visceral organs. Onset of chronic inflammation and oxidative stress not only leads to obesity and heart disease, but also promotes type II diabetes and metabolic syndrome, which are risk factors for both acute neural trauma (stroke) and chronic age-related neurodegenerative and neuropsychological disorders, such as Alzheimer disease (AD), Parkinson disease (PD) and depression.

The Hungry Brain

The Hungry Brain PDF Author: Stephan J. Guyenet, Ph.D.
Publisher: Flatiron Books
ISBN: 1250081238
Category : Health & Fitness
Languages : en
Pages : 304

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Book Description
A Publishers Weekly Best Book of the Year From an obesity and neuroscience researcher with a knack for engaging, humorous storytelling, The Hungry Brain uses cutting-edge science to answer the questions: why do we overeat, and what can we do about it? No one wants to overeat. And certainly no one wants to overeat for years, become overweight, and end up with a high risk of diabetes or heart disease--yet two thirds of Americans do precisely that. Even though we know better, we often eat too much. Why does our behavior betray our own intentions to be lean and healthy? The problem, argues obesity and neuroscience researcher Stephan J. Guyenet, is not necessarily a lack of willpower or an incorrect understanding of what to eat. Rather, our appetites and food choices are led astray by ancient, instinctive brain circuits that play by the rules of a survival game that no longer exists. And these circuits don’t care about how you look in a bathing suit next summer. To make the case, The Hungry Brain takes readers on an eye-opening journey through cutting-edge neuroscience that has never before been available to a general audience. The Hungry Brain delivers profound insights into why the brain undermines our weight goals and transforms these insights into practical guidelines for eating well and staying slim. Along the way, it explores how the human brain works, revealing how this mysterious organ makes us who we are.

Insulin Resistance as a Risk Factor in Visceral and Neurological Disorders

Insulin Resistance as a Risk Factor in Visceral and Neurological Disorders PDF Author: Akhlaq A. Farooqui
Publisher: Academic Press
ISBN: 0128201843
Category : Medical
Languages : en
Pages : 499

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Book Description
Insulin Resistance as a Risk Factor in Visceral and Neurological Disorders provides an overview on the risk factors for insulin resistance in visceral and neurological disorders. The book focuses on molecular mechanisms and signal transduction processes associated with the links. The comprehensive information in this monograph will not only help in the early detection of insulin resistance related visceral and neurological disorders, but also promote the discovery of new drugs which may block or delay onset in elderly patients. Understanding these processes is important not only for patients, caregivers and health professionals, but also for health policymakers who must plan for national resources. - Presents the first comprehensive book dedicated to insulin resistance as a risk factor for neurological disorders - Focuses on the molecular mechanisms and signal transduction processes associated with insulin resistance - Discusses insulin resistance to heart disease, obesity, diabetes, stroke, Alzheimer's, Parkinson's, dementia and depression

Gut Microbiota in Neurologic and Visceral Diseases

Gut Microbiota in Neurologic and Visceral Diseases PDF Author: Tahira Farooqui
Publisher: Academic Press
ISBN: 0128210400
Category : Medical
Languages : en
Pages : 388

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Book Description
Gut Microbiota in Neurologic and Visceral Diseases presents readers with comprehensive information on the involvement of microbiota in the pathogenesis of neurological disorders. Chapters cover the effect of microbiota on the development of visceral (obesity, type 2 diabetes, heart disease) and neurological disorders (Alzheimer's disease, Parkinson's, depression, anxiety, and autism). Sections focus on the molecular mechanisms and signal transduction processes associated with the links among microbiota-related visceral and neurological disorders. It is hoped that this discussion will not only integrate and consolidate knowledge in this field but will also jumpstart more studies on the involvement of microbiota in the pathogenesis of neurological disorders. - Reviews the relationship between gut microbiome, diseases and disorders - Discusses the relationship between diet, microbiota and inflammation - Includes neurodegenerative, neuropsychiatric and cardiovascular disorders - Covers diabetes, obesity and metabolic disorders - Identifies molecular mechanisms and signal transduction processes - Encompasses dietary fiber, fat, prebiotics and probiotics

Molecular Mechanisms of Dementia

Molecular Mechanisms of Dementia PDF Author: Akhlaq A. Farooqui
Publisher: Academic Press
ISBN: 0128167319
Category : Medical
Languages : en
Pages : 387

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Book Description
Considerable progress has been made in neurochemical and therapeutic aspects of dementia research in recent years. Molecular and Therapeutic Aspects of Dementia presents readers with comprehensive and cutting-edge information on the neurochemical mechanisms of various types of dementias. It provides a clearly written and logically organized and comprehensive overview of molecular aspects of risk factors, symptoms, pathogenesis, biomarkers, and therapeutic strategies for various types of dementia. This book is written for the international audience of neurochemists, neuroscientists, neurologists, neuropharmacologists, and clinicians. The hope is that this discussion will not only integrate and consolidate knowledge in this field, but will jumpstart more studies on molecular mechanisms and therapeutic aspects of dementia. The comprehensive information in this monograph may not only help in early detection of various types of dementia and dementia linked neurological disorders, but also promote discovery of new drugs, which may block or delay the onset of dementia in elderly patients. Understanding the course of dementia is important not only for patients, caregivers, and health professionals, but also for health policy-makers, who have to plan for national resources needed in the management of an increasing number of dementia cases. - Provides a comprehensive overview of molecular aspects of risk factors, symptoms, pathogenesis, biomarkers, and therapeutic strategies for various types of dementia - Summarizes cutting edge research information on signal transduction processes associated with neurochemistry of dementia - Discusses the synthesis, metabolism, and role of lipid mediators in dementia

Food Components to Enhance Performance

Food Components to Enhance Performance PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 030905088X
Category : Medical
Languages : en
Pages : 560

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Book Description
The physiological or psychological stresses that employees bring to their workplace affect not only their own performance but that of their co-workers and others. These stresses are often compounded by those of the job itself. Medical personnel, firefighters, police, and military personnel in combat settingsâ€"among othersâ€"experience highly unpredictable timing and types of stressors. This book reviews and comments on the performance-enhancing potential of specific food components. It reflects the views of military and non-military scientists from such fields as neuroscience, nutrition, physiology, various medical specialties, and performance psychology on the most up-to-date research available on physical and mental performance enhancement in stressful conditions. Although placed within the context of military tasks, the volume will have wide-reaching implications for individuals in any job setting.

The "I" Diet

The Author: Susan B. Roberts Ph.D
Publisher: Workman Publishing Company
ISBN: 0761161996
Category : Health & Fitness
Languages : en
Pages : 384

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Book Description
The "I" Diet is a breakthrough: A diet based on impeccable research. A diet where the dieter never goes hungry or feels deprived. A diet that's completely healthy for you, grounded in the metabolic, genetic and psychological workings of the human body. A diet that shows how the hardwired food instincts that once ensured our survival are now driving too many on the road to obesity—and how we can turn those same instincts into an engine for permanent, healthy weight loss. And a fat-burning marvel of a diet that helped the men and women pictured on the cover and inside the book lose 30 pounds on average in a few short months. Start the "I" Diet and be amazed. The diet has been universally praised. From Jane Brody in The New York Times: "Perhaps the most comprehensive approach to eating for effective weight control." From Women's World: "Obesity cure!" From world-class nutritional researchers and scientists: "A real paradigm shift;" "wise guidance along the road to long-term weight management;" "an honest, straightforward and helpful guide." And not to mention from Harvard's Henry Louis Gates Jr., who recommends the book to "anyone who has struggled with weight gain or obesity, and has given up hope. This diet will change their life."

Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders

Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders PDF Author: Akhlaq A. Farooqui
Publisher: Academic Press
ISBN: 0128217014
Category : Medical
Languages : en
Pages : 404

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Book Description
Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders presents readers with comprehensive and cutting-edge information on the neurochemical mechanisms of various types of neurological disorders. The book covers information on signal transduction processes associated with neurochemistry of neurological disorders, including neurodegenerative, neurotraumatic, and neuropsychiatric disorders. The book also discusses risk factors, symptoms, pathogenesis, biomarkers, and the potential treatments of neurological disorders. The comprehensive information in this monograph may not only help in early detection of various neurological disorders, but will also promote the discovery of new drugs. - Provides a comprehensive overview of the molecular aspects of neurodegeneration, neuroprotection, and neuro-regeneration, along with therapeutic strategies for various types of neurological disorders - Provides cutting-edge research information on the signal transduction processes associated with the neurochemistry of neurological disorders - Discusses risk factors, symptoms, pathogenesis, biomarkers, and the potential for treatments of neurological disorders

Neurochemical Aspects of Alzheimer's Disease

Neurochemical Aspects of Alzheimer's Disease PDF Author: Akhlaq A. Farooqui
Publisher: Academic Press
ISBN: 0128099380
Category : Psychology
Languages : en
Pages : 416

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Book Description
Neurochemical Aspects of Alzheimer's Disease provides a comprehensive overview of molecular aspects of risk factors, pathogenesis, biomarkers, and therapeutic strategies. The book focuses on molecular mechanisms and signal transduction processes associated with the pathogenesis, biomarkers, and therapeutic strategies of AD. The comprehensive and cutting edge information in this monograph may not only help in early detection of AD, but also promote discovery of new drugs to treat this chronic disease. Chapters discuss involvement of neural membrane phospholipids, sphingolipids, and cholesterol-derived lipid mediators, abnormal APP processing, and nucleic acid damage, risk factors, biomarker, and therapeutic strategies of Alzheimer's disease. This book is written for neurologists, neuroscientists, neurochemists, neuropharmacologists, and clinicianswho are interested in molecular mechanisms associated with the pathogenesis of age-related neurological disorders. - Provides a comprehensive overview of molecular aspects of risk factors, pathogenesis, biomarkers, and therapeutic strategies for Alzheimer's disease - Written for researchers, clinicians, and advanced graduate students in neurology, neuroscience, neurochemistry, and neuropharmacology - Acts as the first book to provide a comprehensive description of the signal transduction processes associated with pathogenesis of Alzheimer's disease

An Introduction to Nutritional Medicine

An Introduction to Nutritional Medicine PDF Author: John Nichols
Publisher: Cambridge Scholars Publishing
ISBN: 1527557626
Category : Medical
Languages : en
Pages : 153

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Book Description
This book imagines a meeting between Charles Darwin and Hippocrates, the ancient Greek father of medicine, supposing that any dialogue between these two great thinkers should be quite sensational. It presents a short dialogue at the start of each chapter to act as an introduction to the topic discussed. With the help of Darwin and Hippocrates, it covers some of the main areas of the large topic of nutritional medicine, and especially some of the more controversial topics such as the use of nutritional supplements, the efficacy of probiotics and when to categorise a food as “junk food.” Any reader who wants to know what constitutes nutritional medicine (as opposed to homeopathy and herbalism) will find this book a useful introduction to the subject. For those wanting to read up on the subject in greater detail, the appendix of the text includes a comprehensive reading list.