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Author: Jeanne Mager Stellman
Publisher: International Labour Organization
ISBN: 9789221098171
Category : Medical
Languages : en
Pages : 922
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Book Description
Author: Heewon Lee
Publisher: CRC Press
ISBN: 1439874204
Category : Medical
Languages : en
Pages : 540
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Book Description
A great deal of confusion and uncertainty over genotoxic impurity (GTI) identification, assessment, and control exists in the pharmaceutical industry today. Pharmaceutical Industry Practices on Genotoxic Impurities strives to facilitate scientific and systematic consensus on GTI management by presenting rationales, strategies, methods, interpretations, practices, and case studies from the pharmaceutical industry. Featuring the contributions of industry leaders from nine major pharmaceutical companies, this authoritative text: Explores the safety, quality, and regulatory aspects of GTIs Provides an overview of the latest FDA and EMEA guidelines Explains the how and why of various GTI control tactics and practices Describes genotoxicity evaluation, acceptable exposure calculation, and analytical methods for testing Includes real-life examples of GTI control in drug substance and drug product development processes Containing case studies from large and small pharmaceutical firms in multiple geographical regions, Pharmaceutical Industry Practices on Genotoxic Impurities supplies an overview of—and a current framework for—GTI control in the pharmaceutical industry, demonstrating how proper management of GTIs can occur with the appropriate guidance, a firm grasp of the practical implications, and effective information sharing between disciplines.
Author: Inamuddin
Publisher: Springer Nature
ISBN: 3030441768
Category : Science
Languages : en
Pages : 502
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Book Description
Traditional methods in synthetic chemistry produce chemical waste and byproducts, yield smaller desired products, and generate toxic chemical substances, but the past two centuries have seen consistent, greener improvements in organic synthesis and transformations. These improvements have contributed to substance handling efficiency by using green-engineered forerunners like sustainable techniques, green processes, eco-friendly catalysis, and have minimized energy consumption, reduced potential waste, improved desired product yields, and avoided toxic organic precursors or solvents in organic synthesis. Green synthesis has the potential to have a major ecological and monetary impact on modern pharmaceutical R&D and organic chemistry fields. This book presents a broad scope of green techniques for medicinal, analytical, environmental, and organic chemistry applications. It presents an accessible overview of new innovations in the field, dissecting the highlights and green chemistry attributes of approaches to green synthesis, and provides cases to exhibit applications to pharmaceutical and organic chemistry. Although daily chemical processes are a major part of the sustainable development of pharmaceuticals and industrial products, the resulting environmental pollution of these processes is of worldwide concern. This edition discusses green chemistry techniques and sustainable processes involved in synthetic organic chemistry, natural products, drug syntheses, as well various useful industrial applications.
Author: Jeanne Mager Stellman
Publisher: International Labour Organization
ISBN: 9789221098171
Category : Medical
Languages : en
Pages : 922
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Book Description
Author:
Publisher: John Wiley & Sons
ISBN: 3527325921
Category : Science
Languages : en
Pages : 378
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Book Description
The shift towards being as environmentally-friendly as possible has resulted in the need for this important volume on the role of ionic liquids in green chemistry. Edited by Peter Wasserscheid, one of the pioneers of ionic liquid research, and Annegret Stark, this is an essential resource for anyone wishing to gain an understanding of the world of green chemistry, as well as for chemists, environmental agencies and chemical engineers.
Author: International Occupational Safety and Health Information Centre
Publisher:
ISBN:
Category : Industrial hygiene
Languages : en
Pages : 448
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Book Description
Author:
Publisher:
ISBN:
Category : Environmental health
Languages : en
Pages : 824
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Book Description
Author: William Popendorf
Publisher: CRC Press
ISBN: 1351238035
Category : Technology & Engineering
Languages : en
Pages : 781
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Book Description
Are you a practicing occupational hygienist wondering how to find a substitute organic solvent that is safer to use than the hazardous one your company is using? Chapter 6 is your resource. Are you a new hygienist looking for an alternative technology as a nonventilation substitute for an existing hazard? Chapter 8 is your resource. Are you looking for an overview of ventilation? Chapters 10 and 11 are your resource? Are you an industrial hygiene student wanting to learn about local exhaust ventilation? Chapters 13 through 16 are your resource. Are you needing to learn about personal protective equipment and respirators? Chapters 21 and 22 are your resources. This new edition brings all of these topics and more right up-to-date with new material in each chapter, including new governmental regulations. While many of the controls of airborne hazards have their origins in engineering, this author has been diligent in explaining concepts, writing equations in understandable terms, and covering the topics of non-ventilation controls, both local exhaust and general ventilation, and receiver controls at the level needed by most IHs without getting too advanced. Taken as a whole, this book provides a unique, comprehensive tool to learn the challenging yet rewarding role that industrial hygiene can play in controlling airborne chemical hazards at work. Most chapters contain a set of practice problems with the solutions available to instructors. Features Written for the novice industrial hygienist but useful to prepare for ABIH certification Explains engineering concepts but requires no prior engineering background Includes specific learning goals that differentiate the depth of learning appropriate to each topic within the fuller information and explanations provided for each chapter Contains updated governmental regulations and abundant references Presents a consistent teaching philosophy and approach throughout the book Deals with both ventilation and non-ventilation controls
Author: Neal G. Anderson
Publisher: Elsevier
ISBN: 0080514480
Category : Science
Languages : en
Pages : 380
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Book Description
This book provides a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries. Process R&D describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. More people are being hired for work in this area as increasing numbers of drug candidates are identified through combinatorial chemistry and high-throughput screening. The book is directed to industrial (primarily organic) chemists, and academicians (particularly those involved in a growing number of start-up companies) and students who need insight into industrial process R&D. Current books do not describe hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." "Practical Process Research and Development" will be a valuable resource for researchers, managers, and graduate students. - Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules" - Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more - Includes over 100 tips for rapid process development - Presents guidelines for implementing and troubleshooting processes
Author:
Publisher:
ISBN:
Category : Industrial hygiene
Languages : en
Pages : 924
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Book Description
Author:
Publisher:
ISBN:
Category : Dose-response relationship (Biochemistry)
Languages : en
Pages : 428
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Book Description
