Human Herpesviruses

Human Herpesviruses PDF Author: Ann Arvin
Publisher: Cambridge University Press
ISBN: 1139461648
Category : Medical
Languages : en
Pages : 1325

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Book Description
This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.

Human Herpesviruses

Human Herpesviruses PDF Author: Ann Arvin
Publisher: Cambridge University Press
ISBN: 1139461648
Category : Medical
Languages : en
Pages : 1325

Get Book Here

Book Description
This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.

Vascular Responses to Pathogens

Vascular Responses to Pathogens PDF Author: Felicity N.E. Gavins
Publisher: Academic Press
ISBN: 0128013257
Category : Medical
Languages : en
Pages : 254

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Book Description
Vascular Responses to Pathogens focuses on the growing research from leaders in the field for both the short and long-term impact of pathogens on the vasculature. It discusses various organisms, including bacteria, parasites, and viruses, and their role in key events leading to vascular disease. Formatted to discuss the topic of the interaction of pathogens with the vascular rather than individual diseases described separately, this reference demonstrates that common mechanisms are at play in many different diseases because they have a similar context, their vasculature. This all-inclusive reference book is a must-have tool for researchers and practicing clinicians in the areas of vascular biology, microvasculature, cardiology, and infectious disease. - Covers a wide spectrum of organisms and provides analysis of pathogens and current therapeutic strategies in the context of their vasculature - Provides detailed perspectives on key components contributing to vascular pathogens from leaders in the field - Interfaces between both vascular biology and microbiology by encompassing information on how pathogens affect both macro and microvasculature - Includes coverage of the clinical aspects of sepsis and current therapeutic strategies and anti-sepsis drugs

Molecular Virology of Human Pathogenic Viruses

Molecular Virology of Human Pathogenic Viruses PDF Author: Wang-Shick Ryu
Publisher: Academic Press
ISBN: 0128009993
Category : Science
Languages : en
Pages : 441

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Book Description
Molecular Virology of Human Pathogenic Viruses presents robust coverage of the key principles of molecular virology while emphasizing virus family structure and providing key context points for topical advances in the field. The book is organized in a logical manner to aid in student discoverability and comprehension and is based on the author's more than 20 years of teaching experience. Each chapter will describe the viral life cycle covering the order of classification, virion and genome structure, viral proteins, life cycle, and the effect on host and an emphasis on virus-host interaction is conveyed throughout the text. Molecular Virology of Human Pathogenic Viruses provides essential information for students and professionals in virology, molecular biology, microbiology, infectious disease, and immunology and contains outstanding features such as study questions and recommended journal articles with perspectives at the end of each chapter to assist students with scientific inquiries and in reading primary literature. - Presents viruses within their family structure - Contains recommended journal articles with perspectives to put primary literature in context - Includes integrated recommended reading references within each chapter - Provides access to online ancillary package inclusive of annotated PowerPoint images, instructor's manual, study guide, and test bank

Fenner and White's Medical Virology

Fenner and White's Medical Virology PDF Author: Christopher J. Burrell
Publisher: Academic Press
ISBN: 0123751578
Category : Science
Languages : en
Pages : 605

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Book Description
Fenner and White's Medical Virology, Fifth Edition provides an integrated view of related sciences, from cell biology, to medical epidemiology and human social behavior. The perspective represented by this book, that of medical virology as an infectious disease science, is meant to provide a starting point, an anchor, for those who must relate the subject to clinical practice, public health practice, scholarly research, and other endeavors. The book presents detailed exposition on the properties of viruses, how viruses replicate, and how viruses cause disease. These chapters are then followed by an overview of the principles of diagnosis, epidemiology, and how virus infections can be controlled. The first section concludes with a discussion on emergence and attempts to predict the next major public health challenges. These form a guide for delving into the specific diseases of interest to the reader as described in Part II. This lucid and concise, yet comprehensive, text is admirably suited to the needs of not only advanced students of science and medicine, but also postgraduate students, teachers, and research workers in all areas of virology. - Features updated and expanded coverage of pathogenesis and immunity - Contains the latest laboratory diagnostic methods - Provides insights into clinical features of human viral disease, vaccines, chemotherapy, epidemiology, and control

Viral Genome Replication

Viral Genome Replication PDF Author: Craig E. Cameron
Publisher: Springer Science & Business Media
ISBN: 038789456X
Category : Medical
Languages : en
Pages : 636

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Book Description
This book provides the first comprehensive review of viral genome replication strategies, emphasizing not only pathways and regulation but also the structure-function, mechanism, and inhibition of proteins and enzymes required for this process.

Virus Taxonomy

Virus Taxonomy PDF Author: International Committee on Taxonomy of Viruses
Publisher: Elsevier
ISBN: 0123846846
Category : Science
Languages : en
Pages : 1463

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Book Description
The practical need to partition the world of viruses into distinguishable, universally agreed upon entities is the ultimate justification for developing a virus classification system. Since 1971, the International Committee on Taxonomy of Viruses (ICTV) operating on behalf of the world community of virologists has taken on the task of developing a single, universal taxonomic scheme for all viruses infecting animals (vertebrate, invertebrates, and protozoa), plants (higher plants and algae), fungi, bacteria, and archaea. The current report builds on the accumulated taxonomic construction of the eight previous reports dating back to 1971 and records the proceedings of the Committee since publication of the last report in 2005. Representing the work of more than 500 virologists worldwide, this report is the authoritative reference for virus organization, distinction, and structure.

Saliva Protection and Transmissible Diseases

Saliva Protection and Transmissible Diseases PDF Author: Crispian Scully
Publisher: Academic Press
ISBN: 0128136820
Category : Medical
Languages : en
Pages : 124

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Book Description
Saliva Protection and Transmissible Diseases provides a review of saliva protection, raising debate on micro-organisms potentially transmissible in saliva, and also considering the evidence on diseases that may be transmitted by kissing. Saliva is a complex body fluid essential to health, especially mastication, swallowing and speech, and hyposalivation can lead to dysfunction and even infection. More serious pathogens, such as herpes viruses and papillomaviruses can be conveyed by kissing, as can potentially lethal micro-organisms present in some saliva, such as meningococci, fungal organisms and Ebola viruses. - Stipulates the defensive roles of saliva, an important topic not previously reviewed in-depth in literature - Provides awareness that saliva also transmits infectious agents that can produce serious or even lethal diseases - Gives understanding that kissing may be an at-risk practice

Assessment of Future Scientific Needs for Live Variola Virus

Assessment of Future Scientific Needs for Live Variola Virus PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309173191
Category : Medical
Languages : en
Pages : 126

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Book Description
In 1980, the World Health Organization (WHO) officially declared that smallpox had been eradicated. In 1986, WHO's international Ad Hoc Committee on Orthopox Virus Infections unanimously recommended destruction of the two remaining official stocks of variola virus, one at the Centers for Disease Control and Prevention and the other at the VECTOR laboratory in Siberia. In June 1999, WHO decided to delay the destruction of these stocks. Informing that decision was Assessment of Future Scientific Needs for Variola Virus, which examines: Whether the sequenced variola genome, vaccinia, and monkey pox virus are adequate for future research or whether the live variola virus itself is needed to assist in the development of antiviral therapies. What further benefits, if any, would likely be gained through the use of variola in research and development efforts related to agent detection, diagnosis, prevention, and treatment. What unique potential benefits, if any, the study of variola would have in increasing our fundamental understanding of the biology, host-agent interactions, pathogenesis, and immune mechanisms of viral diseases.

Biodefense in the Age of Synthetic Biology

Biodefense in the Age of Synthetic Biology PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309465184
Category : Technology & Engineering
Languages : en
Pages : 189

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Book Description
Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.

Latent Herpes Virus Infections in Veterinary Medicine

Latent Herpes Virus Infections in Veterinary Medicine PDF Author: G. Wittmann
Publisher: Springer Science & Business Media
ISBN: 9400956622
Category : Medical
Languages : en
Pages : 503

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Book Description
This seminar referred to latent herpes virus infections in veterinary medicine, with emphasis on the domestic animals. The phenomenon of latency is of particular importance in veterinary medicine because it can jeopardize the successful control and eradication of diseases such as Aujeszky's disease and infectious bovine rhinotracheitis, diseases which are often the cause of great economic losses. For this reason, the Commission of the European Communities (CEC) realized the importance of summarizing the present state of knowledge on latent herpes virus infections in veterinary medicine. A seminar was therefore organized by the Federal Research Institute for Animal Virus Diseases in Ttibingen, Federal Republic of Germany, from September 21 to 23, 1982, as a part of the 'Animal Pathology Programme' of the CEC. The seminar was attended by 50 participants not only from the countries of the CEC, and 38 papers were selected for presentation. In veterinary medicine, more intensive investigations on the latency of animal herpes viruses have only relatively recently been initiated. In contrast, great efforts have been made for many years to elucidate latency in human and primate herpes viruses, and consequently the most considerable advances have been made in this field. Some of the most experienced scientists working on both systems were therefore invited. As a result, this seminar was the first occasion on which scientists from different countries and faculties investigating herpes virus latency had the opportunity to present and exchange their latest results. The.