Drug-Induced Liver Injury PDF Download
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Author:
Publisher: Academic Press
ISBN: 0128173173
Category : Medical
Languages : en
Pages : 290
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Book Description
Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series
Author:
Publisher: Academic Press
ISBN: 0128173173
Category : Medical
Languages : en
Pages : 290
Get Book Here
Book Description
Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series
Author: Hyman J. Zimmerman
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781719520
Category : Medical
Languages : en
Pages : 850
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Book Description
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Author: Robert C. Bast, Jr.
Publisher: John Wiley & Sons
ISBN: 111900084X
Category : Medical
Languages : en
Pages : 2004
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Book Description
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Author: Minjun Chen
Publisher: Humana Press
ISBN: 9781493976768
Category : Medical
Languages : en
Pages : 667
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Book Description
This book provides a comprehensive view of the methodologies used for the study of liver toxicity encountered throughout the whole life cycle of a drug, from drug discovery, to clinical trial, post-marketing, and even clinical practice. Organized into six sections, the first section introduces the mechanisms contributing to drug-induced liver toxicity. The second and third section explore in silico and in vitro approaches used to help mitigate hepatotoxicity liability at the early stages of drug development. The fourth section describes methodologies applied in regulatory processes, including preclinical studies, clinical trials, and post-marketing surveillance. The fifth section discusses clinical hepatotoxicity. Emerging technologies are examined in the final section. As a volume in the Methods in Pharmacology and Toxicology series, chapters include the kind of expert advice that will lead to optimal results. Authoritative and practical, Drug-Induced Liver Toxicity serves all those who aim to improve assessment and understanding of hepatotoxic potentials of new medications and marketed drugs. Chapter 30 is open access under a CC BY 4.0 license via link.springer.com.
Author: Patricia A. Talcott
Publisher: Elsevier Health Sciences
ISBN: 0323241980
Category : Medical
Languages : uk
Pages : 955
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Book Description
- 20 new chapters have been added - New topics include a list of toxicants affecting body systems, management of toxins in pregnancy, diagnostic toxicology, bacterial toxins, and cosmetic/toilet articles - Snake-bite injuries are treated in two separate, expanded chapters: Pit Vipers and Coral Snakes - Section on pharmaceuticals includes bromides, anticonvulsants, tricycle antidepressants, monoamine oxidize inhibitors, B-adrenergic toxicities, and vitamins A and D - Additional specific toxicants are covered, including Amitraz, hydramethylon, ethanol, mercury, toad toxins, poisonous frogs, salamanders, newts and venomous arthropods•Additional specific toxicants are covered, including Amitraz, hydramethylon, ethanol, mercury, toad toxins, poisonous frogs, salamanders, newts and venomous arthropods.
Author: Lawrence Samuel Friedman
Publisher:
ISBN: 9780443066337
Category : Medical
Languages : en
Pages : 481
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Book Description
Here's instant access to the symptoms, signs, differential diagnosis, and treatment for the full range of liver disorders. Written by an international 'who's who' of hepatology-and now in full color-this new 2nd Edition provides readers with top-notch, authoritative guidance they can count on! Discusses the hottest topics in the field, such as non-alcoholic steatohepatitis (NASH) and the latest information on liver transplantation. Includes expanded coverage of chronic hepatitis C, most notably the use of combination therapy with peginterferon and ribavirin and improvements in the management of the side effects of antiviral therapy. Offers the most recent therapeutic options for the management of chronic hepatitis B and advances in the understanding of the molecular biology of this virus. Updates the approach to the diagnosis of many liver diseases due to newer tests based on molecular techniques and advances in imaging. Features over 340 full-color illustrations. Uses a redesigned templated, outline format that makes reference a snap. Presents a concise, in-depth clinical summary-in an outline format-of the current practice of hepatology for each major disease entity. Provides a liberal use of tables, algorithms, and figures, rendering complex concepts understandable. Includes key point boxes at the beginning of each chapter, providing at-a-glance access to vital information. Includes alert symbols that highlight information that's critical to patient safety.
Author: Ronald Ross Watson
Publisher: Academic Press
ISBN: 0123977649
Category : Technology & Engineering
Languages : en
Pages : 801
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Book Description
Bioactive Food as Dietary Interventions for Liver and Gastrointestinal Disease provides valuable insights for those seeking nutritional treatment options for those suffering from liver and/or related gastrointestinal disease including Crohn's, allergies, and colitis among others. Information is presented on a variety of foods including herbs, fruits, soy and olive oil. This book serves as a valuable resource for researchers in nutrition, nephrology, and gastroenterology. - Addresses the most positive results from dietary interventions using bioactive foods to impact diseases of the liver and gastrointestinal system, including reduction of inflammation, improved function, and nutritional efficiency - Presents a wide range of liver and gastrointestinal diseases and provides important information for additional research - Associated information can be used to understand other diseases, which share common etiological pathways
Author: Pablo Muriel
Publisher: Academic Press
ISBN: 0128043210
Category : Science
Languages : en
Pages : 917
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Book Description
Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants. Written by the most prominent authors in the field, this book will be of use to basic and clinical scientists and clinicians working in the biological sciences, especially those dedicated to the study and treatment of liver pathologies. - Presents the most recent advances in hepatology, with a special focus on the role of oxidative stress in liver injury. - Provides in vivo and in vitro models to study human liver pathology. - Explains the beneficial effects of antioxidants on liver diseases. - Contains the most recent and modern treatments of hepatic pathologies, including, but not limited to, stem cells repopulation, gene therapy and liver transplantation.
Author: Ntambwe Malangu
Publisher: BoD – Books on Demand
ISBN: 1789231388
Category : Medical
Languages : en
Pages : 164
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Book Description
This book is a fruit of a collaborative work from several international scientists. It will be a useful resource for researchers, students, and clinicians. Each individual chapter could serve as a prescribed reading for postgraduate students and clinicians specializing in and practicing clinical pharmacology and toxicology, pharmacotherapy and pharmacotherapeutics, pharmacovigilance, and toxicovigilance, as well as those involved in clinical research, drug discovery, and development. Every chapter in this book discusses and provides illustrations on the theme discussed based on authors' understanding and experience while summarizing existing knowledge. In doing so, each chapter provides a new insight that would benefit a novice as well as a seasoned reader in understanding the pharmacokinetic mechanisms and risk factors involved in the occurrence of adverse effects of drugs.
Author: T Pullaiah
Publisher: CRC Press
ISBN: 1000064778
Category : Health & Fitness
Languages : en
Pages : 794
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Book Description
This important volume provides a comprehensive overview of hepatotoxicity and medicinal plants used for protecting the liver and for curing liver toxicity and liver diseases. To date, there has been no extensive resource on the plants that are used in this capacity, both in traditional medicine and in modern medicine. This book fills that gap. It presents information on the medicinal plants used in traditional medicine (both codified and noncodified) and in ethnomedicine, including the plant parts used and methods of use and dosages. The phytochemicals extracted from medicinal plants,screened and used in modern medicine for liver protection and curing liver problems, are given in detail, and the methods of screening are given as well. Methods of assay for screening the medicinal plants are also presented. Key features: • Provides complete information on plants that show hepatoprotective properties • Lists and discusses the phytochemicals useful for liver protection and cures • Considers traditional uses and ethnomedicinal plants for liver protection • Details the plant parts and the extracts that have protection properties and the active principles showing hepatoprotection
