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Author: Emma Raven
Publisher: Royal Society of Chemistry
ISBN: 1782622624
Category : Science
Languages : en
Pages : 389
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Book Description
Heme peroxidases are widely distributed in biological systems and are involved in a wide range of processes essential for life. This book provides a comprehensive single source of information on the various aspects of heme peroxidase structure, function and mechanism of action. Chapters written and edited by worldwide experts span a range of heme peroxidases from plants, yeast, bacteria and mammals. Discussed functions of peroxidases range from cell wall synthesis, synthesis of prostaglandins, role in drug suppression of tuberculosis, and antibacterial activity. Included is a discussion of peroxidases that also act as catalases and oxygenases. Heme Peroxidases serves as an essential text for those working in industry and academia in biochemistry and metallobiology.
Author: Emma Raven
Publisher: Royal Society of Chemistry
ISBN: 1782622624
Category : Science
Languages : en
Pages : 389
Get Book Here
Book Description
Heme peroxidases are widely distributed in biological systems and are involved in a wide range of processes essential for life. This book provides a comprehensive single source of information on the various aspects of heme peroxidase structure, function and mechanism of action. Chapters written and edited by worldwide experts span a range of heme peroxidases from plants, yeast, bacteria and mammals. Discussed functions of peroxidases range from cell wall synthesis, synthesis of prostaglandins, role in drug suppression of tuberculosis, and antibacterial activity. Included is a discussion of peroxidases that also act as catalases and oxygenases. Heme Peroxidases serves as an essential text for those working in industry and academia in biochemistry and metallobiology.
Author: Emma Raven
Publisher: Royal Society of Chemistry
ISBN: 1849739110
Category : Science
Languages : en
Pages : 388
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Book Description
This book will provide an up to date handbook that is unique in its combination of both the general aspects of heme protein structure and the function in a single volume.
Author: Eduardo Torres
Publisher: Springer Science & Business Media
ISBN: 3642126278
Category : Science
Languages : en
Pages : 360
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Book Description
The last systematic description of heme peroxidases was published in 1999 by Brian Dunford, from the University of Alberta in Canada. The book Heme per- idases covers discussion on three-dimensional structure, reaction mechanism, kinetics, and spectral properties of representative enzymes from bacterial, plant, fungal, and animal origin. Since 1999, vast information on basic but also applied aspects of heme peroxidases has been generated. We believe fusion of these two aspects will bene?t research of those dedicated to development of biocatalytic process. The aim of this book is to present recent advances on basic aspects such as evolution, structure–function relation, and catalytic mechanism, as well as applied aspects, such as bioreactor and protein engineering, in order to provide the tools for rational design of enhanced biocatalysts and biocatalytic processes. The book does not include an exhaustive listing of references but rather a selected collection to enrich discussion and to allow envisioning future directions for research. This book is organized in three parts. In Part I, current knowledge of structure and mechanism of peroxidases is covered. From the molecular phylogeny, going through the in?uence of structural factors over oxidative ability to the molecular mechanism of catalysis, the authors intend to provide an understanding of per- idases at the molecular level. The understanding of the fundamental behavior of peroxidases will allow further adequation, design, and/or optimization of pero- dase-based catalysis to a particular process. In Part II, research on potential applications of peroxidases in several ?elds is presented and discussed.
Author: Clare Hawkins
Publisher: CRC Press
ISBN: 1000450619
Category : Medical
Languages : en
Pages : 340
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Book Description
Mammalian heme peroxidase enzymes play a critical role in innate immune responses and disease prevention. The formation of potent chemical oxidants is essential to this protective physiologic activity in immunity. Although highly beneficial in the context of immune defense, it is now well established that peroxidases and their overproduction of oxidants contribute to the initiation and persistence of many chronic inflammatory conditions in the cardiovascular, neurologic, respiratory, renal, and gastrointestinal systems. Peroxidasins, a protein family related to heme peroxidases, play a novel role in tissue biogenesis and matrix assembly, which are also attracting attention in different pathological contexts. Given the diverse roles of mammalian heme peroxidases and the breadth and incidence of pathologies associated with these enzymes, there has been significant interest in modulating peroxidase activity as a therapeutic strategy. This book highlights recent developments in our understanding of the chemistry, biochemistry and biological roles of mammalian peroxidases and their associated oxidants, their involvement in both innate immunity and chronic inflammatory disease in a variety of end organs, and potential therapeutic approaches to modulate and prevent damaging reactions. Key Features Structure and biosynthesis of mammalian peroxidases Reactivity of hypohalous acids with biological substrates Peroxidases in innate immunity Peroxidases in human pathology Modulation of peroxidase-induced biological damage
Author: J. N. Rodríguez López
Publisher: EDITUM
ISBN: 9788483713792
Category : Mathematics
Languages : en
Pages : 310
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Book Description
Plant Peroxidases: Biochemistry and Physiology recoge los últimos avances en el campo de las peroxidasas vegetales. Las peroxidasas son un grupo de enzimas que se encuentran ampliamente distribuidas en toda la escala filogenética y catalizan la oxidación de un amplio número de sustratos orgánicos e inorgánicos, utilizando el poder oxidante del peróxido de hidrógeno. Además de su interés académico y fisiológico, estas enzimas son ampliamente utilizadas en laboratorios clínicos y en la industria. El presente libro consta de 47 artículos de investigaciónen en los que se tratan diversos aspectos de las peroxidasas como su estructura, enzimología genética, fisiología, localización y aplicaciones. Las aportaciones a este libro han sido realizadas por especialistas de todo el mundo que se reunieron en Murcia en el año 2002 durante el Congreso titulado VI International Plant Peroxidase Symposium
Author: George Georgiou
Publisher:
ISBN:
Category : SCIENCE
Languages : en
Pages : 248
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Book Description
the refolding process is often the critical bottleneck in the production of high-value proteins, and recently acquired insights have yet to be translated into technological advantages. These proceedings bridge the gap between fundamental and applied studies, addressing such issues as in vivo protein folding, protein aggregation and inclusion body formation, elucidation of the folding pathway, characterization of folding intermediates, and practical considerations in protein renaturation. The symposium was part of the 199th ACS National Meeting, Boston, April 1990. Annotation copyrighted by Book News, Inc., Portland, OR
Author: Johannes Everse
Publisher: CRC Press
ISBN: 9780849369636
Category : Medical
Languages : en
Pages : 376
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Book Description
The Peroxidases in Chemistry and Biology series provides up-to-date information on a wide range of developments in the field of Peroxidases, methods and applications. This is Volume 1 originally published in 1990.
Author: B.H. Dunford
Publisher: Springer Science & Business Media
ISBN: 9789027714442
Category : Science
Languages : en
Pages : 542
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Book Description
Proceedings of the NATO Advanced Study Institute, Edmonton, Alberta, Canada, August 23-September 4, 1981
Author: Eugene G. Hrycay
Publisher: Springer
ISBN: 3319160095
Category : Medical
Languages : en
Pages : 376
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Book Description
This book describes in 13 chapters mechanisms of P450 used to monooxygenate substrates via the NAD(P)H/O2 pathway using its peroxidase and peroxygenase functions. P450 also utilizes peroxides, peracids, periodate and iodosobenzene to oxygenate substrates via the shunt pathway. Also described are mechanisms used in the oxidation of pharmaceuticals by CYP3A4; acyl- carbon cleavage by CYP17A1, CYP19A1 and CYP51A1; metabolism of tetrabromodiphenyl ethers and bile acids by CYP2B6 and CYP3A4; metabolism of ω-6 and ω-3 polyunsaturated fatty acids; H2O2-mediated peroxygenation of substrates using substrate misrecognition; P450 oxidative reactions using electrochemical methods; electron transfer to P450 by redox proteins; hydroxylation of 1,8-cineole by P450cin; and peroxygenation by unspecific peroxygenases using H2O2. The topics covered are relevant to P450 researchers, professors and students from a variety of disciplines ranging from pharmacology, toxicology and microbiology to chemistry.
Author: J. A. Cowan
Publisher: John Wiley & Sons
ISBN: 9780471188957
Category : Science
Languages : en
Pages : 458
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Book Description
Das erfolgreiche Werk des jungen, kreativen Autors jetzt in aktualisierter und korrigierter Auflage! Der Text wurde um Fragenkomplexe und Übungsbeispiele, teils mit Lösungen, erweitert; dies empfiehlt ihn besonders zur Ergänzung einer Vorlesung.
