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Author: Torben Heick Jensen
Publisher: Springer Science & Business Media
ISBN: 1441978410
Category : Medical
Languages : en
Pages : 161
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Book Description
The diversity of RNAs inside living cells is amazing. We have known of the more “classic” RNA species: mRNA, tRNA, rRNA, snRNA and snoRNA for some time now, but in a steady stream new types of molecules are being described as it is becoming clear that most of the genomic information of cells ends up in RNA. To deal with the enormous load of resulting RNA processing and degradation reactions, cells need adequate and efficient molecular machines. The RNA exosome is arising as a major facilitator to this effect. Structural and functional data gathered over the last decade have illustrated the biochemical importance of this multimeric complex and its many co-factors, revealing its enormous regulatory power. By gathering some of the most prominent researchers in the exosome field, it is the aim of this volume to introduce this fascinating protein complex as well as to give a timely and rich account of its many functions. The exosome was discovered more than a decade ago by Phil Mitchell and David Tollervey by its ability to trim the 3’end of yeast, S. cerevisiae, 5. 8S rRNA. In a historic account they laid out the events surrounding this identification and the subsequent birth of the research field. In the chapter by Kurt Januszyk and Christopher Lima the structural organization of eukaryotic exosomes and their evolutionary counterparts in bacteria and archaea are discussed in large part through presentation of structures.
Author: Torben Heick Jensen
Publisher: Springer Science & Business Media
ISBN: 1441978410
Category : Medical
Languages : en
Pages : 161
Get Book Here
Book Description
The diversity of RNAs inside living cells is amazing. We have known of the more “classic” RNA species: mRNA, tRNA, rRNA, snRNA and snoRNA for some time now, but in a steady stream new types of molecules are being described as it is becoming clear that most of the genomic information of cells ends up in RNA. To deal with the enormous load of resulting RNA processing and degradation reactions, cells need adequate and efficient molecular machines. The RNA exosome is arising as a major facilitator to this effect. Structural and functional data gathered over the last decade have illustrated the biochemical importance of this multimeric complex and its many co-factors, revealing its enormous regulatory power. By gathering some of the most prominent researchers in the exosome field, it is the aim of this volume to introduce this fascinating protein complex as well as to give a timely and rich account of its many functions. The exosome was discovered more than a decade ago by Phil Mitchell and David Tollervey by its ability to trim the 3’end of yeast, S. cerevisiae, 5. 8S rRNA. In a historic account they laid out the events surrounding this identification and the subsequent birth of the research field. In the chapter by Kurt Januszyk and Christopher Lima the structural organization of eukaryotic exosomes and their evolutionary counterparts in bacteria and archaea are discussed in large part through presentation of structures.
Author: Ross Galbreath
Publisher:
ISBN:
Category : History
Languages : en
Pages : 268
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Book Description
" ... Describes the development of wildlife administration and management in New Zealand which led to this combination of functions in the Wildlife Service, and the changes in attitudes towards wildlife and conservation which eventually in 1987 brought about its replacement. Against this background of shifting ideas and policies, "Working for wildlife" also presents the exploits and achievements of the dedicated band of Wildlife officers. They were pre-eminently people of action rather than bureaucratic administrators: fisheries technicians wading in chilly streams to record and measure migrating trout; fauna conservation field officers and scientists searching for the last of the kakapo in the precipitous Fiordland country, or scaling the cliffs of Little Mangere Island to find ways to rescue the black robins ; deer-cullers in the hills fighting the "Deer Menace". They were the original good keen men; the exploits of those who worked for Wildlife will stir the pride of all New Zealanders."--Back cover.
Author: Charlotte Lance
Publisher: Allen & Unwin
ISBN: 1743317816
Category : Juvenile Fiction
Languages : en
Pages : 36
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Book Description
I have a dog. An inconvenient dog. When I wake up, my dog is inconvenient. When I'm getting dressed, my dog is inconvenient. And when I'm making tunnels, my dog is SUPER inconvenient. But sometimes, an inconvenient dog can be big and warm and cuddly. Sometimes, an inconvenient dog can be the most comforting friend in the whole wide world.
Author: Clay Dawson
Publisher: Jove Books
ISBN: 9781557731746
Category :
Languages : en
Pages : 196
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Book Description
There is something about gold that makes a white man go crazy. And Danville was right in the middle of the richest gold and silver territory in the world. Long Rider was not looking for a fortune when he rode into town. But what he found was a town gone mad with gold fever and a tycoon mad with jealousy.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 16
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Book Description
Author: Harley Laroux
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Jessica Martin is not a nice girl. As Prom Queen and Captain of the cheer squad, she'd ruled her school mercilessly, looking down her nose at everyone she deemed unworthy. The most unworthy of them all? The "freak," Manson Reed: her favorite victim. But a lot changes after high school. A freak like him never should have ended up at the same Halloween party as her. He never should have been able to beat her at a game of Drink or Dare. He never should have been able to humiliate her in front of everyone. Losing the game means taking the dare: a dare to serve Manson for the entire night as his slave. It's a dare that Jessica's pride - and curiosity - won't allow her to refuse. What ensues is a dark game of pleasure and pain, fear and desire. Is it only a game? Only revenge? Only a dare? Or is it something more? The Dare is an 18+ erotic romance novella and a prequel to the Losers Duet. Reader discretion is strongly advised. This book contains graphic sexual scenes, intense scenes of BDSM, and strong language. A full content note can be found in the front matter of the book.
Author: Ann Druffel
Publisher: Granite Pub Llc
ISBN: 9780926524583
Category : Body, Mind & Spirit
Languages : en
Pages : 609
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Book Description
The authorised biography of Dr James E McDonald's research into the UFO phenomenon. McDonald worked in the 1950s and 1960s to raise the UFO issue in the scientific community as a serious problem. This book documents his brave fight for justice and truth, and his untimely and mysterious end. McDonald is a largely forgotten hero in the long and important battle to uncover the truth of the alien presence on Earth. With this landmark work, Ann Druffel places McDonald clearly where he belongs among the great pioneers of UFOlogy.
