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Author: Wanda M. Haschek
Publisher: Academic Press
ISBN: 0128218290
Category : Medical
Languages : en
Pages : 1154
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Book Description
Haschek and Rousseaux's Handbook of Toxicologic Pathology, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive and timely coverage. The fourth edition has been expanded to four separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, Volume 1, "Principles and the Practice of Toxicologic Pathology," covers the practice of toxicologic pathology in three parts: Principles of Toxicologic Pathology, Methods in Toxicologic Pathology, and the Practice of Toxicologic Pathology. Other volumes in this work round out the depth and breadth of coverage.Volume 2 encompasses "Toxicologic Pathology in Safety Assessment" and "Environmental Toxicologic Pathology". These two sections cover the application of toxicologic pathology in developing specific product classes, principles of data interpretation for safety assessment, and toxicologic pathology of major classes of environmental toxicants. Volumes 3 and 4 provide deep and broad treatment of "Target Organ Toxicity", emphasizing the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. These volumes comprise the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Each volume is being published separately. - Provides new chapters on digital pathology, juvenile pathology, in vitro/in vivo correlation, big data technologies and in-depth discussion of timely topics in the area of toxicologic pathology - Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology - Features hundreds of full-color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations
Author: Wanda M. Haschek
Publisher: Academic Press
ISBN: 0128218290
Category : Medical
Languages : en
Pages : 1154
Get Book Here
Book Description
Haschek and Rousseaux's Handbook of Toxicologic Pathology, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive and timely coverage. The fourth edition has been expanded to four separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, Volume 1, "Principles and the Practice of Toxicologic Pathology," covers the practice of toxicologic pathology in three parts: Principles of Toxicologic Pathology, Methods in Toxicologic Pathology, and the Practice of Toxicologic Pathology. Other volumes in this work round out the depth and breadth of coverage.Volume 2 encompasses "Toxicologic Pathology in Safety Assessment" and "Environmental Toxicologic Pathology". These two sections cover the application of toxicologic pathology in developing specific product classes, principles of data interpretation for safety assessment, and toxicologic pathology of major classes of environmental toxicants. Volumes 3 and 4 provide deep and broad treatment of "Target Organ Toxicity", emphasizing the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. These volumes comprise the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Each volume is being published separately. - Provides new chapters on digital pathology, juvenile pathology, in vitro/in vivo correlation, big data technologies and in-depth discussion of timely topics in the area of toxicologic pathology - Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology - Features hundreds of full-color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations
Author: Wanda M. Haschek
Publisher: Academic Press
ISBN: 0323910521
Category : Medical
Languages : en
Pages : 694
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Book Description
Haschek and Rousseaux's Handbook of Toxicologic Pathology, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive and timely coverage. The fourth edition has been expanded to five separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, Volume 2: Toxicologic Pathology in Safety Assessment is an essential part of the most authoritative reference on toxicologic pathology principles and techniques for assessing product safety and human risk. Volume 2 describes the integration of product-induced structural and functional changes in tissues and the interpretation of their biological implications. Completely revised with many new chapters, Volume 2 of the Fourth Edition covers product safety assessment from many angles including current and emerging issues in toxicologic pathology for many product classes. Volume 2 of the Handbook of Toxicologic Pathology is a key resource for pathologists, toxicologists, research scientists, and regulators who use toxicologic pathology methods to study and make decisions on product safety. - Previous chapters on such topics as drug discovery and development, toxicity and carcinogenicity testing, report preparation, and risk assessment and communication have undergone extensive revision that includes in-depth discussion of new developments in the field - New chapters consider fundamental attributes for additional product classes including protein therapeutics, nucleic acid pharmaceutical agents, gene therapy and gene editing, stem cell and other cell therapies, vaccines, agricultural and bulk chemicals, and assigning adversity - Chapters dealing with product-specific practices address pathology and regulatory issues - Chapters offer high-quality and up-to-date content in a trusted work written by the collaborative efforts of many leading international subject matter experts - Hundreds of full-color images and diagrams are featured in both the print and electronic versions of this book to illustrate classic examples and highlight difficult concepts
Author: Wanda M. Haschek
Publisher: Elsevier
ISBN: 032399282X
Category : Medical
Languages : en
Pages : 910
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Book Description
Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume Four: Toxicologic Pathology of Organ Systems is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. Organ systems covered include cardiac, vascular and skeletal muscle systems and the endocrine, respiratory, reproductive, digestive and nervous systems. Completely revised with a new olfactory chapter, this new release is an essential part of the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. - Presents updated chapters on systems toxicologic pathology, including new chapter on olfactory - Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology - Features hundreds of full-color images in both the print and electronic versions to highlight difficult concepts with clear illustrations
Author: Wanda M. Haschek
Publisher: Elsevier
ISBN: 0443161542
Category : Medical
Languages : en
Pages : 974
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Book Description
Haschek and Rousseaux's Handbook of Toxicologic Pathology, Fourth Edition, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive coverage. The fourth edition has been expanded to five separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, this book covers the toxicologic pathology of major classes of environmental toxicants. Volumes emphasize the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. This series comprises the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Each volume is being published separately. - Provides updated and revised chapters for in-depth discussions of toxicologic pathology for the protection of the environment and food supplies - Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology - Features hundreds of full-color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations
Author: Dr. Sanjeev Kumar
Publisher: JEC PUBLICATION
ISBN: 9361750046
Category : Medical
Languages : en
Pages : 248
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Book Description
It gives me great pleasure to recommend this book on clinical pathology and biochemistry to everyone who is interested in the dynamic and ever-evolving field of medical research. The study and use of biochemical concepts and diagnostic tools to comprehend disease processes and direct therapeutic treatments are fundamental disciplines in contemporary medicine, including biochemistry and clinical pathology. The goal of this book is to provide researchers, students, and medical professionals an all-encompassing and up-to-date review of the basic ideas, procedures, and applications of biochemistry and clinical pathology. This book's content has been carefully chosen to address a broad range of subjects, from the interpretation of clinical laboratory tests and their diagnostic importance to the biochemical underpinnings of cellular activity. Every chapter is carefully designed to make learning and application easier. It provides clear explanations, practical examples, and insights from both conventional wisdom and the most recent scientific research. In a time when the integration of contemporary and traditional medicine is becoming more widely acknowledged, healthcare professionals need to have a strong foundation in clinical pathology and biochemistry in order to provide patients evidence-based, comprehensive care. My heartfelt appreciation goes out to all of the reviewers, writers, and supporters whose knowledge and commitment helped to develop this book. Their insightful criticism and steadfast assistance have been crucial in guaranteeing the calibre and applicability of the information offered on these pages. I also want to thank the publishing staff for all of their help and professionalism throughout the publishing process. I urge you to join me as we set out on this exciting voyage of research and discovery as we dig into the fascinating fields of clinical pathology and biochemistry. I really hope that this book becomes a reliable and valuable tool for you as you pursue greatness and knowledge in the area of medical science.
Author: Wanda M Haschek
Publisher: Academic Press
ISBN: 0124157653
Category : Medical
Languages : en
Pages : 3055
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Book Description
Haschek and Rousseaux's Handbook of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. The 3e has been expanded by a full volume, and covers aspects of safety assessment not discussed in the 2e. Completely revised with many new chapters, it remains the most authoritative reference on toxicologic pathology for scientists and researchers studying and making decisions on drugs, biologics, medical devices and other chemicals, including agrochemicals and environmental contaminants. New topics include safety assessment, the drug life cycle, risk assessment, communication and management, carcinogenicity assessment, pharmacology and pharmacokinetics, biomarkers in toxicologic pathology, quality assurance, peer review, agrochemicals, nanotechnology, food and toxicologic pathology, the environment and toxicologic pathology and more. - Provides new chapters and in-depth discussion of timely topics in the area of toxicologic pathology and broadens the scope of the audience to include toxicologists and pathologists working in a variety of settings - Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology - Features hundreds of full color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations
Author: P. Nagarajan
Publisher: Springer Nature
ISBN: 981160987X
Category : Science
Languages : en
Pages : 797
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Book Description
This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research.It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used for human diseases. It also highlights aspects, such as handling and restraint and administration of drugs, as well as breeding and feeding of laboratory animals, and provides guidelines for developing meaningful experiments using laboratory animals.Further, the book discusses various alternatives to animal experiments for drug and chemical testing, including their advantages over the current approaches. Lastly, it examines the potential effect of harmful pathogens on the physiology of laboratory animals and discusses the state of art in in vivo imaging techniques.The book is a useful resource for research scientists, laboratory animal veterinarians, and students of laboratory animal medicine.
Author: Amy Jnah, DNP, NNP-BC
Publisher: Springer Publishing Company
ISBN: 0826158846
Category : Medical
Languages : en
Pages : 913
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Book Description
"This book is a rare find for APRNs, especially PNPs and NNPs, and provides excellent APRN collaboration instances in everyday clinical and academic settings. The chapters are written by interprofessional healthcare providers, such as NNPs and PharmDs, and provide information and practice guidelines from a collaborative perspective. " –Holly Wei, PhD, RN, CPN, NEA-BC, FAAN Professor and Assistant Dean for PhD Program University of Louisville School of Nursing This is the first text to address fetal and neonatal pharmacology for the APN and nursing student. With a strong focus on interprofessional collaboration, it delivers core pharmacologic concepts and practice guidelines in a clear, systematic manner for ease of use. This resource reflects real-word scenarios as it discusses perinatal and intrapartum pharmacologic therapies and their implications for fetuses and neonates. It covers such postnatal pharmacology considerations as human milk and maternal drug addiction. A table including 100 of the most commonly used medications prescribed in the NICU serves as a quick reference for both academic and clinical settings. The text explores the genesis, evolution, and current knowledge surrounding pharmacologic therapies used to treat common problems afflicting preterm and critically ill neonates. Chapters, written by interprofessional teams, include illustrations and concept maps of key content—promoting active learning for visual and tactile learners, learning objectives, and discussion questions. The text meets the accreditation requirements for MSN and DNP programs offering the 3P courses to neonatal and pediatric NP students, Clinical Nurse Specialist students, and midwifery students. Key Features: Provides clear, concise descriptions of principles of fetal and neonatal pharmacology Includes illustrations and concept maps providing visual and tactile learners with tools to engage and demonstrate active learning Presents illustrations and "concept maps" of key content to foster active learning for visual and tactile learners Offers Learning Objectives and Discussion Questions in each chapter Includes a table of 100 commonly used NICU medications Provides core curricular content, written by interprofessional author teams, which aligns with the 2021 AACN Essentials and 2022 NTFS Standards for Quality Nurse Practitioner Education
Author: Wanda M. Haschek
Publisher: Elsevier
ISBN: 0080491448
Category : Medical
Languages : en
Pages : 2160
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Book Description
A comprehensive understanding of toxicologic pathology is essential for those in industry, academia, and government who make decisions concerning the safety and efficacy of drugs and chemicals. Toxicologic pathology relies heavily on the fields of both toxicology and pathology, which are well covered individually in various texts and references; however, there are few texts that address the field of toxicologic pathology. The Handbook of Toxicologic Pathology fills this void and is thus essential for all health professionals within or interacting with the field of toxicologic pathology. This two-volume set provides the reader with a single reference for toxicologic pathology. In volume I, the book covers toxicologic pathology in its basic aspects, including its definition, the basic biochemical and morphologic mechanisms underlying the discipline, the basic practice of toxicologic pathology (including special techniques) and issues essential to the understanding of toxicologic pathology such as risk assessment, experimental design, and statistical analysis. Next, the book moves to specific issues affecting the "practice" toxicologic pathology, including issues such as knowledge management, regulatory affairs and writing pathology reports. Finally, Volume I closes with several chapters that deal with specific classes of environmental toxicants such as endocrine disruptors and heavy metals. Volume II addresses the toxicologic pathology in a thoroughly standardized systems manner, addressing the basic structure and function of a particular organ system, its response to toxic injury, mechanisms of injury and methods of evaluation of such injury. Key Features * Easy to find, up-to-date reference information * Graphic and photographic plates * Current hot topics and anticipated changes in toxicologic pathology * Standardized chapter format * Topics that are addressed in both a broad and deep manner, resulting in a stand alone text * Added coverage of important environmental toxicants * Chapters authored by internationally recognized experts and peer-reviewed
Author:
Publisher: Academic Press
ISBN: 0128137258
Category : Technology & Engineering
Languages : en
Pages : 1055
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Book Description
This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology's subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools.Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology's presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field.The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children's environmental health. - Introductory chapters provide a backdrop to the science of toxicology, its history, the origin and status of toxicoinformatics, and starting points for identifying resources - Offers an extensive array of chapters organized by subject, each highlighting resources such as journals, databases,organizations, and review articles - Includes chapters with an emphasis on format such as government reports, general interest publications, blogs, and audiovisuals - Explores recent internet trends, web-based databases, and software tools in a section on the online environment - Concludes with a miscellany of special topics such as laws and regulations, chemical hazard communication resources, careers and professional education, K-12 resources, funding, poison control centers, and patents - Paired with Volume Two, which focuses on global resources, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over 120 chapters contributions by experts and leaders in the field
