Handbook of Human Tissue Sources. A National Resource of Human Tissue Samples

Handbook of Human Tissue Sources. A National Resource of Human Tissue Samples PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 263

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Book Description
One aspect of the recent and rapid advances in biological and medical research is that human tissue is being used in an increasing variety of new ways. Now that techniques exist to extract DNA from minuscule archival samples, Including frozen blood or tissue samples and even paraffin-embedded tissue blocks, genetic tests could potentially be performed on virtually any size stored tissue sample. These technological advances, which have been so instrumental in recent biomedical discoveries, have also raised several legal, ethical, and societal issues, including concerns about privacy and informed consent.

Handbook of Human Tissue Sources. A National Resource of Human Tissue Samples

Handbook of Human Tissue Sources. A National Resource of Human Tissue Samples PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 263

Get Book Here

Book Description
One aspect of the recent and rapid advances in biological and medical research is that human tissue is being used in an increasing variety of new ways. Now that techniques exist to extract DNA from minuscule archival samples, Including frozen blood or tissue samples and even paraffin-embedded tissue blocks, genetic tests could potentially be performed on virtually any size stored tissue sample. These technological advances, which have been so instrumental in recent biomedical discoveries, have also raised several legal, ethical, and societal issues, including concerns about privacy and informed consent.

The Stored Tissue Issue

The Stored Tissue Issue PDF Author: Robert F. Weir
Publisher: Oxford University Press
ISBN: 0195123689
Category : Medical
Languages : en
Pages : 358

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Book Description
This book provides a thorough, well-balanced analysis of common research practices with banked tissues, DNA, and genetic data. Describing many examples of beneficial tissue research, the authors focus on problematic research practices, controversial cases, and federal and institutional policies that limit the informed choices of patients and research participants. They offer a series of recommendations to help overcome these problems.

Case Studies of Existing Human Tissue Repositories

Case Studies of Existing Human Tissue Repositories PDF Author: Elisa Eiseman
Publisher: Rand Corporation
ISBN: 0833035932
Category : Medical
Languages : en
Pages : 247

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Book Description
Case studies of twelve existing human biospecimen repositories performed to evaluate their utility for genomics- and proteomics-based cancer research and to identify "best practices" in collection, processing, annotation, storage, privacy, ethical concerns, informed consent, business plans, operations, intellectual property rights, public relations, marketing, and education that would be useful in designing a national biospecimen network.

Monitoring Human Tissues for Toxic Substances

Monitoring Human Tissues for Toxic Substances PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309044375
Category : Science
Languages : en
Pages : 224

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Book Description
The National Human Monitoring Program (NHMP) identifies concentrations of specific chemicals in human tissues, including toxicologic testing and risk assessment determinations. This volume evaluates the current activities of the NHMP; identifies important scientific, technical, and programmatic issues; and makes recommendations regarding the design of the program and use of its products.

Tietz Textbook of Laboratory Medicine - E-Book

Tietz Textbook of Laboratory Medicine - E-Book PDF Author: Nader Rifai
Publisher: Elsevier Health Sciences
ISBN: 0323834671
Category : Medical
Languages : en
Pages : 4232

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Book Description
Use THE definitive reference for laboratory medicine and clinical pathology! Tietz Textbook of Laboratory Medicine, 7th Edition provides the guidance necessary to select, perform, and evaluate the results of new and established laboratory tests. Comprehensive coverage includes the latest advances in topics such as clinical chemistry, genetic metabolic disorders, molecular diagnostics, hematology and coagulation, clinical microbiology, transfusion medicine, and clinical immunology. From a team of expert contributors led by Nader Rifai, this reference includes access to wide-ranging online resources on Expert Consult — featuring the comprehensive product with fully searchable text, regular content updates, animations, podcasts, over 1300 clinical case studies, lecture series, and more. Authoritative, current content helps you perform tests in a cost-effective, timely, and efficient manner; provides expertise in managing clinical laboratory needs; and shows how to be responsive to an ever-changing environment. Current guidelines help you select, perform, and evaluate the results of new and established laboratory tests. Expert, internationally recognized chapter authors present guidelines representing different practices and points of view. Analytical criteria focus on the medical usefulness of laboratory procedures. Use of standard and international units of measure makes this text appropriate for any user, anywhere in the world. Expert Consult provides the entire text as a fully searchable eBook, and includes regular content updates, animations, podcasts, more than 1300 clinical case studies, over 2500 multiple-choice questions, a lecture series, and more. NEW! 19 additional chapters highlight various specialties throughout laboratory medicine. NEW! Updated, peer-reviewed content provides the most current information possible. NEW! The largest-ever compilation of clinical cases in laboratory medicine is included on Expert Consult. NEW! Over 100 adaptive learning courses on Expert Consult offer the opportunity for personalized education.

Biobanking of Human Biospecimens

Biobanking of Human Biospecimens PDF Author: Pierre Hainaut
Publisher: Springer Nature
ISBN: 3030559017
Category : Medical
Languages : en
Pages : 210

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Book Description
Over the past 25 years, biobanks of human specimens have become a cornerstone for research on human health and have empowered the “omics “revolution that characterizes biomedical science in the XXIst Century. Today, biobanking of human specimens is a critical component of the interface between clinical practice and translational research, supporting the discovery and validation of new biomarkers of disease etiology, risk, early detection, diagnosis, prognosis, prediction and relapse. With the development of personalized medicine, biobanking of cryopreserved specimens has become standard practice in order to investigate genetic, transcriptomic, proteomic, metabolomics and immunological biomarkers useful to inform caregivers for therapeutic decisions. Data generated from biobanked specimens represent a rapidly growing and highly valuable resource, participating in the emergence of Big Data Medicine. With the development of large computing capabilities and artificial intelligence, data associated with biobanked specimens constitute a unique resource for the discovery and validation of new biomarkers and therapeutically actionable targets. Interconnecting, interoperating and sharing this data have become major issues for national health systems, raising enormous stakes as well as major societal, legal and cybersecurity challenges in terms of compliance with the protection of personal sensitive information. This book project is the second part of an initiative launched in 2012 to produce a published corpus of knowledge encompassing all aspects of human biobanking as a central practice for research and medicine. The first volume, published in 2017, is entitled: Human Biobanking: Principles and Practice. This first volume compiled a series of high level contributions overseeing the main developments that carried the progression of human biobanking as a research and biotechnological field over the past two decades. This new book project will constitute de facto Volume 2 of the same initiative, under the title: Biobanking of Human Biospecimens: lessons from 25 years of biobanking experience. Hence, the two volumes will share the same generic title (Biobanking of Human Biospecimens), with different subtitles, making clear that the two volumes are interrelated while highlighting their specificities in terms of what they actually cover. As a result, the two books are “twins” but can also be used independently of each other. The overarching aim of the two volumes of Biobanking of Human Biospecimens is to provide a published “one-stop shop” for state-of-the-art information on what constitutes the field of human biobanking, from conception of a biobank, standard operating procedures, ethical and societal aspects, governance, networking, interoperability and economic sustainability. This inclusive publication concept meets the needs of a vast readership, including scientists, doctors and technical staffs who are directly involved in biobanking operations, scientists in other disciplines that heavily rely on biobanking (such as genomics or proteomics), stakeholders and policy makers, and of course students for whom biobanking is becoming an important part of the training curriculum. So far, there has been a lack of major textbooks on biobanking. Documentation for biobanking is widely available through numerous publications, regulatory documents published by International or Governmental Agencies, and sets of recommendations essentially accessible through the Internet. However, it is difficult to access a single, top-of-the shelf reference that provides at a glance a large coverage of all aspects of human biobanking. Fulfilling this need is the main origin of the concept for this back-to-back publication project. To our knowledge, there is currently no other publication project with the same breath and scope as this one in the field of biobanking.

Genetic Databases

Genetic Databases PDF Author: Oonagh Corrigan
Publisher: Routledge
ISBN: 1134373341
Category : Social Science
Languages : en
Pages : 228

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Book Description
Genetic Databases offers a timely analysis of the underlying tensions, contradictions and limitations of the current regulatory frameworks for, and policy debates about, genetic databases. Drawing on original empirical research and theoretical debates in the fields of sociology, anthropology and legal studies, the contributors to this book challenge the prevailing orthodoxy of informed consent and explore the relationship between personal privacy and the public good. They also consider the multiple meanings attached to human tissue and the role of public consultations and commercial involvement in the creation and use of genetic databases. The authors argue that policy and regulatory frameworks produce a representation of participation that is often at odds with the experiences and understandings of those taking part. The findings present a serious challenge for public policy to provide mechanisms to safeguard the welfare of individuals participating in genetic databases.

Management of Chemical and Biological Samples for Screening Applications

Management of Chemical and Biological Samples for Screening Applications PDF Author: Mark Wigglesworth
Publisher: John Wiley & Sons
ISBN: 3527645268
Category : Medical
Languages : en
Pages : 435

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Book Description
Filling an obvious gap in the scientific literature, this practice-oriented reference is the first to tie together the working knowledge of large screening centers in the pharmaceutical and biotechnological field. It spans the entire fi eld of this emerging discipline, from compound acquisition to collection optimization for specific purposes, to technology and quality control. In so doing, it applies two decades of expertise gathered by several large pharmaceutical companies to current and future challenges in high-throughput screening. With its treatment of libraries of small molecules as well as biobanks containing biomolecules, microorganisms and tissue samples, this reference is universally applicable for any molecular scientist involved in a large screening program.

Journal of the National Cancer Institute

Journal of the National Cancer Institute PDF Author:
Publisher:
ISBN:
Category : AIDS (Disease)
Languages : en
Pages : 1092

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Book Description


Human Tissue Samples

Human Tissue Samples PDF Author: United States Congress House of Represen
Publisher: Scholar's Choice
ISBN: 9781296011826
Category :
Languages : en
Pages : 296

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Book Description
This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.