Handbook of Hemorheology and Hemodynamics PDF Download
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Author: Oguz K. Baskurt
Publisher: IOS Press
ISBN: 1586037714
Category : Medical
Languages : en
Pages : 468
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Book Description
This publication primarily focuses on the macro- and micro- rheological behavior of blood and its formed elements, on interactions between the formed elements and blood vessel walls, and on the microvascular aspects of hemodynamics. Since many aspects of hemorheology and hemodynamics are affected by disease or clinical states, these effects are discussed as are hyperviscosity syndromes, therapy for disturbed blood rheology, and methods in hemorheology and hemodynamics. Sections of the Handbook include History of Hemorheology; Hemorheology, covering basic aspects, blood composition, blood rheology, cell mechanics, pathophysiology, methods and comparative studies; Hemodynamics, covering basic principles, microcirculation, in vivo effects, endothelium and methods; and Clinical Aspects of Hemorheology, covering hyperviscosity, clinical significance and treatment. The goal is to foster greater interchange between workers in the fields so as to promote collaborative efforts and, hopefully, improved health. In selecting topics for this handbook the editors have attempted to provide a general overview of both basic science and clinical hemorheology and hemodynamics. Hemorheology and hemodynamics are closely related, the former dealing with all aspects of the flow and interactions of the individual blood cells mostly studied in vitro, the latter with the in vivo relationships among vessel architecture, driving pressure, flow rate and shear stress. The linkage between the in vitro and in vivo research described in the book will be of interest to both basic science and clinical investigators. The editors of the handbook have each been active in the fields of bio- and hemorheology for many years, and have published extensively. They have successfully achieved their objective to publish a well-written and well-edited handbook that will be valuable for researchers and students in the field.
Author: Oguz K. Baskurt
Publisher: IOS Press
ISBN: 1586037714
Category : Medical
Languages : en
Pages : 468
Get Book Here
Book Description
This publication primarily focuses on the macro- and micro- rheological behavior of blood and its formed elements, on interactions between the formed elements and blood vessel walls, and on the microvascular aspects of hemodynamics. Since many aspects of hemorheology and hemodynamics are affected by disease or clinical states, these effects are discussed as are hyperviscosity syndromes, therapy for disturbed blood rheology, and methods in hemorheology and hemodynamics. Sections of the Handbook include History of Hemorheology; Hemorheology, covering basic aspects, blood composition, blood rheology, cell mechanics, pathophysiology, methods and comparative studies; Hemodynamics, covering basic principles, microcirculation, in vivo effects, endothelium and methods; and Clinical Aspects of Hemorheology, covering hyperviscosity, clinical significance and treatment. The goal is to foster greater interchange between workers in the fields so as to promote collaborative efforts and, hopefully, improved health. In selecting topics for this handbook the editors have attempted to provide a general overview of both basic science and clinical hemorheology and hemodynamics. Hemorheology and hemodynamics are closely related, the former dealing with all aspects of the flow and interactions of the individual blood cells mostly studied in vitro, the latter with the in vivo relationships among vessel architecture, driving pressure, flow rate and shear stress. The linkage between the in vitro and in vivo research described in the book will be of interest to both basic science and clinical investigators. The editors of the handbook have each been active in the fields of bio- and hemorheology for many years, and have published extensively. They have successfully achieved their objective to publish a well-written and well-edited handbook that will be valuable for researchers and students in the field.
Author: Oguz Baskurt
Publisher: CRC Press
ISBN: 1439841802
Category : Medical
Languages : en
Pages : 326
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Book Description
Red blood cells in humans—and most other mammals—have a tendency to form aggregates with a characteristic face-to-face morphology, similar to a stack of coins. Known as rouleaux, these aggregates are a normally occurring phenomenon and have a major impact on blood rheology. What is the underlying mechanism that produces this pattern? Does this really happen in blood circulation? And do these rouleaux formations have a useful function? The first book to offer a comprehensive review of the subject, Red Blood Cell Aggregation tackles these and other questions related to red blood cell (RBC) aggregates. The book covers basic, clinical, and physiological aspects of this important biophysical phenomenon and integrates these areas with concepts in bioengineering. It brings together state-of-the-art research on the determinants, mechanisms, and measurement and effects of RBC aggregation as well as on variations and comparative aspects. After an introductory overview, the book outlines factors and conditions that affect RBC aggregation. It presents the two hypotheses—the bridging model and the depletion model—that provide potential mechanisms for the adhesive forces that lead to the regular packing of the cells in rouleaux formations. The book also reviews the methods used to quantify RBC aggregation in vitro, focusing on their importance in clinical practice. Chapters discuss the effect of RBC aggregation on the in vitro rheology of blood as well as on tube flow. The book also looks at what happens in the circulation when red blood cells aggregate and examines variations due to physiological and pathophysiological challenges. The concluding chapter explores the formation of red blood cell aggregates in other mammals. Written by leading researchers in the field, this is an invaluable resource for basic science, medical, and clinical researchers; graduate students; and clinicians interested in mammalian red blood cells.
Author:
Publisher: IOS Press
ISBN:
Category :
Languages : en
Pages : 10439
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Book Description
Author: Giles R. Cokelet
Publisher: Morgan & Claypool Publishers
ISBN: 1615041621
Category : Medical
Languages : en
Pages : 143
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Book Description
From the perspective of blood flow, blood has some unusual properties: it is a suspension of blood cells of which the red blood cells are most numerous and are both deformable (at moderate and high flow rates) and will aggregate under conditions of slow flow. Also, the cellular volume concentration is high (about 40-45%). These features cause blood to have variable viscosity, dependent on flow conditions, and cause both red blood cell sedimentation and syneresis effects under slow flow conditions (which can lead to rheological artifacts). These effects also cause unusual flow phenomena when blood flows in systems of small diameter vessels (especially for diameters of about 500 μm or less). These phenomena are seen in non-uniform cell distributions in vessel cross sections, a cell-poor layer of mostly blood plasma at vessels walls, non-proportionate cellular distribution during blood flow through vascular bifurcations, which leads to a very wide distribution of vessel cellular concentrations (from zero to systemic values) in the smaller vessels of the microcirculation, etc. All these phenomena are discussed in this book, as well as the difficulties presented by in vivo microvessels having non-ideal geometries. Table of Contents: Introduction / The Composition of Blood / Viscometers / Constitutive Equations / At Last, Experimental Data! / Some In Vitro Blood Flows / The Fahraeus Effect / The Fahreus-Lindqvist Effect / In Vitro Arterial-Type Bifurcation Experimental Data / In Vivo Experimental Bifurcation Data / Flow in Microvascular Networks / Optimization / Concluding Statement / References
Author: Oguz Baskurt
Publisher: CRC Press
ISBN: 1439841810
Category : Medical
Languages : en
Pages : 310
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Book Description
Red blood cells in humans-and most other mammals-have a tendency to form aggregates with a characteristic face-to-face morphology, similar to a stack of coins. Known as rouleaux, these aggregates are a normally occurring phenomenon and have a major impact on blood rheology. What is the underlying mechanism that produces this pattern? Does this real
Author: Antonio Fasano
Publisher: Springer
ISBN: 3319605135
Category : Mathematics
Languages : en
Pages : 352
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Book Description
This book illustrates applications of mathematics to various processes (physiological or artificial) involving flowing blood, including hemorheology, microcirculation, coagulation, kidney filtration and dialysis, offering a historical overview of each topic. Mathematical models are used to simulate processes normally occurring in flowing blood and to predict the effects of dysfunctions (e.g. bleeding disorders, renal failure), as well as the effects of therapies with an eye to improving treatments. Most of the models have a completely new approach that makes patient-specific simulations possible. The book is mainly intended for mathematicians interested in medical applications, but it is also useful for clinicians such as hematologists, nephrologists, cardio-surgeons, and bioengineers. Some parts require no specific knowledge of mathematics. The book is a valuable addition to mathematics, medical, biology, and bioengineering libraries.
Author: Shannan Hamlin
Publisher: Elsevier Health Sciences
ISBN: 0323323200
Category : Medical
Languages : en
Pages : 153
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Book Description
Critical care clinicians must be knowledgeable about the anatomic, physiologic, and biochemical processes that are critical to the restoration of a functioning microvascular affecting organ perfusion. These basic physiologic processes critical to tissue perfusion and cellular oxygenation are presented in this issue on Monitoring Tissue Perfusion and Oxygenation. A working knowledge of oxygen delivery and oxygen consumption at the microvascular level will provide critical information needed for clinicians to continuously question the adequacy of tissue perfusion given our current lack of microvascular bedside monitoring.
Author: Philippe Connes
Publisher: IOS Press
ISBN: 1607504960
Category : Medical
Languages : en
Pages : 692
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Book Description
There is no doubt that if the field of exercise physiology is to make further advancements, the various specialized areas must work together in solving the unique and difficult problems of understanding how exercise is initiated, maintained and regulated at many functional levels, and what causes us to quit. Exercise is perhaps the most complex of physiological functions, requiring the coordinated, integrated activation of essentially every cell, tissue and organ in the body. Such activation is known to take place at all levels - from molecular to systemic. Focusing on important issues addressed at cellular and systemic levels, this handbook presents state-of-the-art research in the field of exercise physiology. Each chapter serves as a comprehensive resource that will stimulate and challenge discussion in advanced students, researchers, physiologists, medical doctors and practitioners. Authored by respected exercise physiologists from nineteen countries, each chapter has been significantly updated to provide up-to-date coverage of the topics and to offer complete descriptions of the many facets of the most physiological responses from a cellular to an integrative approach within individual body systems in normal and disease states and includes some chapters that are rarely addressed in exercise physiology books, such as the influence of exercise on endothelium, vasomomotor control mechanisms, coagulation, immune function and rheological properties of blood, and their influence on hemodynamics. This book represents the first iteration to provide such a work. Normal exercise responses divided into muscle function, bioenergetics, and respiratory, cardiac and blood/vascular function; Fitness, training, exercise testing and limits to exercise; Exercise responses in different environments; Beneficial effects of exercise rehabilitation on ageing and in the prevention and treatment of disease states; Rarely addressed issues such as the influence of exercise on endothelium, vasomotor control mechanisms, coagulation, immune function and rheological properties of blood and their influence on hemodynamics. IOS Press is an international science, technical and medical publisher of high-quality books for academics, scientists, and professionals in all fields. Some of the areas we publish in: -Biomedicine -Oncology -Artificial intelligence -Databases and information systems -Maritime engineering -Nanotechnology -Geoengineering -All aspects of physics -E-governance -E-commerce -The knowledge economy -Urban studies -Arms control -Understanding and responding to terrorism -Medical informatics -Computer Sciences
Author: Ali Ostadfar
Publisher: Academic Press
ISBN: 0128026006
Category : Science
Languages : en
Pages : 384
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Book Description
Biofluid Mechanics is a throrough reference to the entire field. Written with engineers and clinicians in mind, this book covers physiology and the engineering aspects of biofluids. Effectively bridging the gap between engineers' and clinicians' knowledge bases, the text provides information on physiology for engineers and information on the engineering side of biofluid mechanics for clinicians. Clinical applications of fluid mechanics principles to fluid flows throughout the body are included in each chapter. All engineering concepts and equations are developed within a biological context, together with computational simulation examples as well. Content covered includes; engineering models of human blood, blood rheology in the circulation system and problems in human organs and their side effects on biomechanics of the cardiovascular system. The information contained in this book on biofluid principles is core to bioengineering and medical sciences. - Comprehensive coverage of the entire biofluid mechanics subject provides you with an all in one reference, eliminating the need to collate information from different sources - Each chapter covers principles, needs, problems, and solutions in order to help you identify potential problems and employ solutions - Provides a novel breakdown of fluid flow by organ system, and a quick and focused reference for clinicians
Author: Ayse Basak Engin
Publisher: CRC Press
ISBN: 1466582790
Category : Medical
Languages : en
Pages : 462
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Book Description
The function and life span of endothelial cells have a large impact upon the quality and expectancy of an individual's life. During low perfusion, the adaptation of different cells to hypoxia precipitate the aggressive progression of diseases. Although the clinical studies have convincingly shown that endothelial dysfunction occurs whenever the biological functions or bioavailability of nitric oxide are impaired, in all these scenarios, the role of endothelial cell-destructive process cross-talk is yet poorly understood. This book focuses on the contribution of molecular mechanisms to endothelial dysfunction in related metabolic disorders.
