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Category : Carcinogenicity testing
Languages : en
Pages : 0
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Book Description
This volume of the IARC Monographs provides an assessment of the carcinogenicity of 14 drugs and herbal products. The IARC Monographs Working Group relied on epidemiological studies to evaluate the carcinogenic hazard to humans exposed to the drugs digoxin (widely prescribed for the treatment of chronic heart failure), pioglitazone (used for the treatment of type 2 diabetes mellitus), and hydrochlorothiazide (used to treat hypertension). Other agents evaluated included the drugs primidone, sulfasalazine, pentosan polysulfate sodium, and triamterene, and five herbal products (or their components): Aloe vera whole leaf extract, goldenseal root powder, Ginkgo biloba leaf extract, kava extract, and pulegone. In view of the limited agent-specific information available from epidemiological studies, assessments of these agents relied mainly on carcinogenicity bioassays to reach conclusions as to the carcinogenic hazard to exposed humans.
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ISBN:
Category : Carcinogenicity testing
Languages : en
Pages : 0
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Book Description
This volume of the IARC Monographs provides an assessment of the carcinogenicity of 14 drugs and herbal products. The IARC Monographs Working Group relied on epidemiological studies to evaluate the carcinogenic hazard to humans exposed to the drugs digoxin (widely prescribed for the treatment of chronic heart failure), pioglitazone (used for the treatment of type 2 diabetes mellitus), and hydrochlorothiazide (used to treat hypertension). Other agents evaluated included the drugs primidone, sulfasalazine, pentosan polysulfate sodium, and triamterene, and five herbal products (or their components): Aloe vera whole leaf extract, goldenseal root powder, Ginkgo biloba leaf extract, kava extract, and pulegone. In view of the limited agent-specific information available from epidemiological studies, assessments of these agents relied mainly on carcinogenicity bioassays to reach conclusions as to the carcinogenic hazard to exposed humans.
Author: E.W. Fünfgeld
Publisher: Springer Science & Business Media
ISBN: 3642736866
Category : Medical
Languages : en
Pages : 360
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Book Description
In this compendium the clinical and pharmacological properties of Ginkgo biloba, a standardized drug and the subject of increasing worldwide interest, are closely portrayed. Results of studies are presented here which illustrate the influence of Ginkgo on haemodynamic and rheologic parameters, metabolism and neurotransmitters. In addition to papers reporting on experimental research, data are also presented which provide firm interdisciplinary evidence for its successful therapeutic application, above all in the following indication areas: cerebral insufficiency with accompanying symptoms of dizziness, tinnitus, headache and memory loss, lability of mood and anxious states, and peripheral arterial disease.
Author: Teris A vanBeek
Publisher: CRC Press
ISBN: 0203304942
Category : Science
Languages : en
Pages : 565
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Book Description
A present and up-to-date overview of this particular genus, the contents of this volume include a history of its use, biotechnology, extraction of ginkgo leaves and extensive coverage of the ginkolides; their discovery, biosynthesis, chemical analysis, clinical use and pharmacological activity. Other important constituents are also given attention.
Author: Peter Crane
Publisher: Yale University Press
ISBN: 0300190476
Category : Science
Languages : en
Pages : 689
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Book Description
DIVPerhaps the world’s most distinctive tree, ginkgo has remained stubbornly unchanged for more than two hundred million years. A living link to the age of dinosaurs, it survived the great ice ages as a relic in China, but it earned its reprieve when people first found it useful about a thousand years ago. Today ginkgo is beloved for the elegance of its leaves, prized for its edible nuts, and revered for its longevity. This engaging book tells the full and fascinating story of a tree that people saved from extinction—a story that offers hope for other botanical biographies that are still being written./divDIV /divDIVInspired by the historic ginkgo that has thrived in London’s Kew Gardens since the 1760s, renowned botanist Peter Crane explores the evolutionary history of the species from its mysterious origin through its proliferation, drastic decline, and ultimate resurgence. Crane also highlights the cultural and social significance of the ginkgo: its medicinal and nutritional uses, its power as a source of artistic and religious inspiration, and its importance as one of the world’s most popular street trees. Readers of this extraordinarily interesting book will be drawn to the nearest ginkgo, where they can experience firsthand the timeless beauty of the oldest tree on Earth./div
Author: Hyman J. Zimmerman
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781719520
Category : Medical
Languages : en
Pages : 848
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Book Description
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Author: Francis V. DeFeudis
Publisher:
ISBN: 9783861261735
Category : Extracts
Languages : en
Pages : 401
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Book Description
Author: Shahid Akbar M.D. Ph.D.
Publisher: Trafford Publishing
ISBN: 1698708394
Category : Reference
Languages : en
Pages : 181
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Book Description
Ginkgo biloba leaf has been used as Chinese herbal medicine to treat a variety of health disorders for centuries, especially for vascular insufficiency. As dietary supplement, Ginkgo ranks among the most extensively used phytopharmaceutical products in the United States, and around the world. More than 24 different brands of Ginkgo extract are sold in the United States. In Europe, Ginkgo leaf extract EGb 761® is a registered drug for the treatment of age-related cognitive decline, including memory and concentration problems. Clinical studies have demonstrated effectiveness of Ginkgo extract in a wide range of health problems associated with cerebrovascular insufficiency. However, it is primarily known and appreciated for its effects on age-related decline in cognition and memory. This book discusses the results of published scientific studies regarding its various anecdotal uses.
Author: Mark Paul Mattson
Publisher: Springer Science & Business Media
ISBN: 9781402071294
Category : Medical
Languages : en
Pages : 284
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Book Description
"Diet - Brain Connections fills a void between the fields of nutrition, behavior and cellular and molecular neurosciences by providing an integrated collection of articles that critically dissect the link between what we eat and how the brain develops and functions in health and disease ... This book provides an unprecedented resource for scientists in academia and government labs as well as in the pharmaceutical, nutraceutical and food industries" -- Back cover.
Author: Hyla Cass
Publisher: Basic Health Publications, Inc.
ISBN: 9781591200192
Category : Health & Fitness
Languages : en
Pages : 100
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Book Description
In the months following the September 11 attacks, world leaders began a flurry of attempts to muzzle the press. Some governments prevented journalists from covering anti-US demonstrations or criticizing US policies. Others opportunistically adopted the rhetoric of the war on terrorism to justify repressive measures against the media. Still other leaders took a cue from the tactics used by the US military in Afghanistan to keep the press away from the battlefield.
Author: A. Agnoli
Publisher:
ISBN:
Category : Brain damage
Languages : en
Pages : 124
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Book Description
